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N/A Completed N=306 Randomized Health Services Research

Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices

Carcinoma In Situ · Current Smoker · Malignant Neoplasm · Primary Neoplasm
Source: ClinicalTrials.gov NCT03808818 ↗
Enrolled (actual)
306
Serious AEs
7.5%
Results posted
Mar 2025
Primary outcomePrimary: Biochemically-confirmed 7-day Point Prevalence Abstinence at 6 Months (Not Evaluated)

Summary

This phase II trial studies how well smoking cessation treatment plans work in tobacco-dependent cancer patients when delivered virtually as part of their cancer care in community oncology practices. Virtual information and counseling sessions may help cancer patients quit smoking.

Outcome Measures

OutcomeResultp-value
PRIMARY
Biochemically-confirmed 7-day Point Prevalence Abstinence at 6 Months (Not Evaluated)
SECONDARY
Biochemically-confirmed 7-day Point Prevalence Abstinence at 3 Months (Not Evaluated)
SECONDARY
7-day Point-prevalence Tobacco Abstinence at 6 Months - Self Report
21; 42 0.0046 sig
SECONDARY
7-day Point-prevalence Tobacco Abstinence at 3 Months - Self Report
22; 38 0.035 sig
SECONDARY
Self-reported Continuous Tobacco Abstinence
13; 28 0.016 sig
SECONDARY
Sustained Tobacco Abstinence at 6 Months (Not Evaluated)
SECONDARY
Significant Reduction in Smoking
47; 64 0.069
SECONDARY
Significant Reduction in Smoking @ 3 Months
53; 57 0.86

Eligibility Criteria

Inclusion Criteria

  • STAFF ELIGIBILITY CRITERIA:
  • Must be English speaking.
  • Must be employed at NCI Community Oncology Research Program (NCORP) site for at least three months.
  • PATIENT ELIGIBILITY CRITERIA STEP 0:
  • Patient presenting with any type of cancer with a date of diagnosis within the past 4 months. Recurrence, diagnosed within the last 4 months, of tumors in patients with past cancer diagnoses will be considered eligible. Patients with a new primary cancer, diagnosed within the last 4 months, who have been treated previously for other types of cancer will also be considered eligible. ?In situ? cancers, diagnosed within the past 4 months, will also be considered eligible.
  • Patient must be a current smoker. Current smoker is defined as any cigarette smoking (even a puff) in the past 30 days.
  • Patient must be fluent in both, written and spoken, English or both, written and spoken, Spanish.
  • Patient must have telephone, e-mail access, and have access to the internet with a camera-enabled device (e.g., smartphone, tablet, computer, laptop with a webcam/camera)
  • NOTE: The restriction to those with web and e-mail access is based on the primary intention of the study; to assess the implementation of the virtual intervention in the NCORP network.
  • ELIGIBILITY CRITERIA STEP 1: Patient must still meet all criteria outlined in step 0.
  • ELIGIBILITY STEP 2 (RANDOMIZATION): Patient must have completed baseline survey in Eastern Cooperative Oncology Group-American College of Radiology Imaging Network (ECOG-ACRIN) Cancer Research Group Systems for Easy Entry of Patient Reported Outcomes (EASEEPRO) within 1 month (30 days) of the date of informed consent (Step 1).

Exclusion Criteria

  • Patient has an Eastern Cooperative Oncology Group (ECOG) performance status of 3 or above, or is deemed medically unable to participate by study investigators or oncology clinician (i.e., referral to hospice).
  • Patient has no intention to receive their cancer care or monitoring at an NCORP community cancer site.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03808818). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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