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Hemithyroidectomy is associated with a 3% higher risk difference in cancer recurrence rate
ONCOLOGY
Hemithyroidectomy is associated with a 3% higher risk difference in cancer recurrence rate Hemithyroidectomy linked to higher thyroid cancer recurrence
Jun 17, 2026
This meta-analysis of 98,604 patients with differentiated thyroid carcinoma found that hemithyroidectomy (HT) was associated with a 3% higher risk difference in…
A large meta-analysis found that hemithyroidectomy for differentiated thyroid cancer has a higher recurrence rate than total thyroidectomy, with about 8% vs 6% …
Transcatheter aortic valve replacement shows comparable mortality to surgery in severe symptomatic aortic stenosis
NEUROLOGY
Transcatheter aortic valve replacement shows comparable mortality to surgery in severe symptomatic aortic stenosis Trial compares TAVR and surgery for aortic stenosis
Jun 17, 2026
This trial compared transcatheter aortic valve replacement with surgical aortic valve replacement in patients with severe symptomatic aortic stenosis at low sur…
A large trial shows that while TAVR and surgery have similar survival rates, TAVR may lead to more frequent follow-up procedures over time.
Anti-CD19 shRNA-engineered CAR-T cells achieve an 88% overall response rate in B-cell acute lymphoblastic leukemia
ONCOLOGY
Anti-CD19 shRNA-engineered CAR-T cells achieve an 88% overall response rate in B-cell acute lymphoblastic leukemia CAR-T Cells Show Promise for B-cell Acute Lymphoblastic Leukemia
Jun 17, 2026
This meta-analysis evaluates anti-CD19 shRNA-engineered CAR-T cells (interleukin-6 knockdown) for patients with B-cell acute lymphoblastic leukemia. The analysi…
New research into modified CAR-T cells shows high response rates in patients with a specific type of leukemia while managing serious side effects.
HIFU ranks highest for fibroid volume reduction and hormonal stability in network meta-analysis
ONCOLOGY
HIFU ranks highest for fibroid volume reduction and hormonal stability in network meta-analysis High intensity focused ultrasound shows promise for uterine fibroids
Jun 17, 2026
This network meta-analysis of 2622 women with symptomatic uterine fibroids indicates that HIFU ranked highest for fibroid volume reduction, recurrence preventio…
A review of 2,622 patients suggests high-intensity focused ultrasound is highly effective at shrinking fibroid size and preventing regrowth.
Olanzapine significantly improves complete response and total control in chemotherapy-induced nausea for breast cancer
ONCOLOGY
Olanzapine significantly improves complete response and total control in chemotherapy-induced nausea for breast cancer Olanzapine helps manage nausea in breast cancer chemotherapy
Jun 17, 2026
This meta-analysis of 4 studies involving 857 patients found that olanzapine with regular antiemetic treatment improved complete response (RR 1.58) and total co…
Adding olanzapine to standard care can significantly improve nausea control and complete response for patients undergoing breast cancer chemotherapy.
Rural Ugandan adolescents show higher prevalence of ideal cardiovascular health than urban peers
CARDIOLOGY
Rural Ugandan adolescents show higher prevalence of ideal cardiovascular health than urban peers Rural Ugandan adolescents show higher heart health than urban peers
Jun 17, 2026
This cross-sectional study of 1,316 Ugandan adolescents found a 66.8% overall prevalence of ideal cardiovascular health (CVH). Prevalence was significantly high…
A new look at heart health in Uganda shows that rural teens have better cardiovascular markers than those living in urban areas.
Fecal microbiota transplantation improves motor function and constipation in patients with Parkinson disease
NEUROLOGY
Fecal microbiota transplantation improves motor function and constipation in patients with Parkinson disease Fecal transplants improve Parkinson's motor symptoms in short term
Jun 17, 2026
This meta-analysis of 220 adults with mild to moderate Parkinson disease found that fecal microbiota transplantation (FMT) significantly improved motor function…
A meta-analysis finds fecal transplants may temporarily improve motor and constipation symptoms in Parkinson's, but effects fade.
Pseudoprogression in immune checkpoint inhibitor therapy is associated with modest tumor growth and early progression
ONCOLOGY
Pseudoprogression in immune checkpoint inhibitor therapy is associated with modest tumor growth and early progression Immune Checkpoint Inhibitors May Cause Initial Tumor Growth in Cancer
Jun 17, 2026
This meta-analysis of retrospective data examines patients with solid tumors experiencing pseudoprogression during immune checkpoint inhibitor therapy. The anal…
A growing tumor during immunotherapy might actually be a sign that the treatment is working, not a sign that the cancer is spreading.
WBRT yields median survival of 3.6 months in Nigerian brain metastases patients
ONCOLOGY
WBRT yields median survival of 3.6 months in Nigerian brain metastases patients Brain radiation extends life by 3.6 months in Nigerian patients
Jun 17, 2026
This systematic review of 142 patients with brain metastases in Nigeria found that whole brain radiotherapy (WBRT) was associated with a median survival of 3.6 …
Whole brain radiotherapy gave Nigerian breast cancer patients with brain metastases a median survival of 3.6 months. A new review reveals the real-world outcome…
Immunomodulatory interventions targeting the ovarian immune microenvironment may address functional decline in aging and POI
ONCOLOGY
Immunomodulatory interventions targeting the ovarian immune microenvironment may address functional decline in aging and POI Immune system changes drive ovarian aging and fertility decline
Jun 17, 2026
This systematic review examines how dysregulation of the local ovarian immune microenvironment, including Treg/Th17 balance and macrophage polarization, drives …
New research identifies how the immune environment in the ovaries drives age-related decline and may offer a path for new treatments.
Luspatercept and ESA-based regimens show higher rates of erythroid haematological improvement in lower-risk MDS
ONCOLOGY
Luspatercept and ESA-based regimens show higher rates of erythroid haematological improvement in lower-risk MDS Different Medications Show Different Benefits for Myelodysplastic Syndromes
Jun 17, 2026
This systematic review and network meta-analysis of 20 trials involving 2,877 participants evaluated pharmacological treatments for lower-risk myelodysplastic s…
New research shows different medications offer varying benefits for patients with lower-risk myelodysplastic syndromes based on specific health goals.
Large language models provide consistent informational quality but low verifiability for varicose veins information
PRIMARY CARE & FAMILY MEDICINE
Large language models provide consistent informational quality but low verifiability for varicose veins information AI models provide similar quality information on varicose veins
Jun 17, 2026
This benchmarking study evaluated 100 responses from five large language models regarding varicose veins. While models achieved similar informational quality sc…
Different AI tools give similar quality answers about varicose veins, but they all struggle to provide verifiable medical evidence.