Phase 2 Completed N=48 Randomized Double-blind Treatment

Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy

Postoperative Pain

Source: ClinicalTrials.gov NCT01242644 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2020

Primary outcomePrimary: Pain Score 8 Hours Post-operativley — 2.5; 1.8; 1.06 units on a scale

Summary

Hypothesis: Ropivacaine, morphine and ketorolac injected after knee arthroscopy is as effective as this solution plus ropivacaine administered intra-articularly for twenty-four hours. Three groups were assigned random patients, each group provided a different method of pain medication in order to determine the effectiveness of each treatment.

Outcome Measures

Outcome	Result	p-value
PRIMARY Pain Score 8 Hours Post-operativley	2.5; 1.8; 1.06	—
PRIMARY Pain Scale	3.3; 4.05; 3.13	—
SECONDARY Number of Narcotic Pills and Morphine Sulfate Used	2.1; 2.7; 1.7	—

Eligibility Criteria

Inclusion Criteria: All subjects who underwent:

knee arthroscopy + synovectomy
knee arthroscopy + partial or complete meniscectomy
knee arthroscopy + chondroplasty
knee arthroscopy + microfracture
knee arthroscopy + autologous osteoarticular transplantation

Exclusion Criteria

A surgical procedure that required an incision other then an arthroscopic portal
A surgical procedure within the same joint within ninety days
A acute or chronic knee infection
Any diagnosis of complex regional pain syndrome
A known allergy to one of the study drugs
A documented history of narcotic use
A score of less than two standard deviation on the SF-12 mental component
Any major systemic or cardiac illness (heart failure, uncontrolled angina, bifascicular blocks, renal insufficiency, or liver disease)
Under the age of eighteen years

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01242644). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.