HEART score sensitivity 0.96 vs GRACE 0.88 for 30-day MACE in ED chest pain
HEART score better than GRACE at spotting heart attack risk in emergency room patients
This systematic review and meta-analysis of 14,862 ED patients with acute chest pain compared the HEART and GRACE scores for predicting 30-d…
A large review shows the HEART score is better at finding people with heart attacks than the GRACE score, helping doctors safely discharge l…
Systematic review finds aerobic exercise combined with other therapies helps reduce neck pain intensity and improve physical function in adults
Combined neck pain treatments beat aerobic exercise alone
A systematic review of six studies indicates that aerobic exercise alone shows no significant benefit over no treatment for neck pain. Howev…
Mixing aerobic exercise with other therapies helps reduce neck pain better than doing cardio by itself, according to new research on adults.
VR and music therapy alleviate anxiety, chronic pain, and cognitive impairment in diverse patients
Virtual reality and music therapy ease anxiety, pain, and brain fog
A scoping review of 34 articles found that integrating Virtual Reality and Music Therapy significantly alleviates symptoms of anxiety, chron…
A review of 34 studies finds VR combined with music therapy significantly reduces anxiety, chronic pain, and cognitive impairment.
Whole health team intervention reduced pain interference by 0.58 points versus cognitive behavioral therapy in VA patients
A new team approach offers small but real relief for chronic pain in VA patients
This randomized clinical trial enrolled 764 patients with chronic pain receiving VA primary care across six US health systems. Participants …
A new team approach offers small but real relief for chronic pain in VA patients compared to standard care or group therapy sessions.
AI and machine learning improve patient selection and outcomes in spinal cord stimulation
AI may help optimize spinal cord stimulation for chronic pain patients
A mini review suggests AI and ML can optimize patient selection and outcomes for spinal cord stimulation, potentially reducing device failur…
A mini review suggests AI tools could improve spinal cord stimulation outcomes for chronic pain, potentially lowering costs and device failu…
Review of dopamine receptor targeting for chronic pain and mood disorders notes limited causal evidence
Treating dopamine receptors offers new hope for chronic pain and mood disorders
This narrative review examines the role of dopamine receptor system treatment in chronic pain and mood disorders. The authors synthesize fin…
Targeting dopamine receptors shows promise for managing chronic pain and mood issues, though more patient trials are needed to confirm benef…
Review of nicotinic acetylcholine receptors in neuropathic, inflammatory, and cancer-related pain
Nicotinic receptors may help treat several types of pain
This narrative review examines the role of nicotinic acetylcholine receptors in neuropathic, inflammatory, and cancer-related pain. The auth…
A new review suggests targeting nicotinic receptors could ease neuropathic, inflammatory, and cancer pain. More research is needed to confir…
Meta-analysis finds minimal benefit of liposomal bupivacaine in TAP blocks for postoperative pain
Liposomal bupivacaine shows minimal benefit for postoperative pain
This meta-analysis of 1528 patients compared liposomal bupivacaine to standard bupivacaine in transversus abdominis plane blocks for postope…
A review of 1,528 patients found liposomal bupivacaine in TAP blocks offers only small reductions in pain and opioid use after surgery.
Meta-analysis shows VR reduces pain in adult ICU patients receiving conventional care
Virtual reality headsets lower pain scores for adults in the ICU
This meta-analysis and systematic review evaluated virtual reality technology in adult ICU patients. The analysis pooled data from 979 patie…
A review of five studies found that virtual reality headsets with nature scenes significantly reduced pain scores for adults in the ICU.
Psychological interventions significantly reduce anxiety and depression in cancer pain patients compared to conventional care
Cancer Pain Patients Find Unexpected Relief Through Talk Therapy
This meta-analysis evaluated psychological interventions for anxiety and depression in cancer pain patients. The analysis included 879 parti…
• Talk therapy cuts anxiety and depression scores by nearly 9 points • Helps patients suffering pain during chemotherapy or radiation • Not …
Acupuncture combined with Chinese medicine reduces cancer pain intensity compared to usual care in a meta-analysis of 884 patients
Cancer Patients Feel Less Pain With Acupuncture and Herbal Therapy Today
This systematic review and meta-analysis evaluated acupuncture combined with Chinese medicine versus acupuncture alone, analgesic therapy, o…
• Acupuncture plus Chinese herbs cuts cancer pain better than standard treatments • Helps people with moderate to severe pain from cancer ca…
Narrative synthesis on liposomal bupivacaine for autologous breast reconstruction pain
New Pain Strategy Cuts Opioid Use After Breast Surgery
This narrative synthesis reviews evidence on liposomal bupivacaine for autologous breast reconstruction. It finds some studies show reduced …
• May reduce opioid use by 20-30% in some cases • Helps women after breast reconstruction surgery • Works best with specific pain plans, not
Questions about Postoperative Pain
How does spinal cord injury change my brain's response to tDCS therapy?
Spinal cord injury disrupts brain homeostatic plasticity, reducing the normal inhibitory response to repeated tDCS and potentially altering its pain-relieving effects.
Full answer →Does repetitive transcranial magnetic stimulation help neuropathic pain after spinal cord injury?
Yes, repetitive transcranial magnetic stimulation (rTMS) can help reduce neuropathic pain after spinal cord injury, based on meta-analyses and clinical guidelines.
Full answer →Is a mindfulness intervention a feasible option for managing chronic pain after cancer?
Yes, a mindfulness intervention (MORE) is feasible for managing chronic pain in cancer survivors, based on a pilot RCT showing good enrollment, adherence, and satisfaction.
Full answer →Do people with chronic pain and depression show changes in their brain structure?
Yes, people with both chronic pain and depression show measurable differences in brain structure, including reduced volume in key regions and altered white matter, according to a large UK Biobank study.
Full answer →Can a mobile app help me manage my chronic pain in primary care?
Yes, a mobile app can help manage chronic pain in primary care by providing self-management tools, but evidence is still emerging and app quality varies.
Full answer →What themes do nurses identify regarding pain management for pediatric patients?
Nurses identify five key themes in pediatric pain management: feeling defeated by pain, importance of family participation, need for better assessment tools, challenges with medication administration, and desire for more training.
Full answer →Can acupuncture help cancer patients relieve their symptoms according to recent surveys?
Yes, a 2025 survey found 94% of cancer patients are willing to try acupuncture, mainly for sleep, pain, and fatigue relief.
Full answer →Will an animated video reduce pain during a prostate biopsy procedure?
Yes, a randomized controlled trial found that watching an animated video before a transperineal prostate biopsy significantly reduced pain during the procedure and improved patient satisfaction.
Full answer →All Postoperative Pain Articles
- HEART score sensitivity 0.96 vs GRACE 0.88 for 30-day MACE in ED chest pain
- Systematic review finds aerobic exercise combined with other therapies helps reduce neck pain intensity and improve physical function in adults
- VR and music therapy alleviate anxiety, chronic pain, and cognitive impairment in diverse patients
- Whole health team intervention reduced pain interference by 0.58 points versus cognitive behavioral therapy in VA patients
- AI and machine learning improve patient selection and outcomes in spinal cord stimulation
- Review of dopamine receptor targeting for chronic pain and mood disorders notes limited causal evidence
- Review of nicotinic acetylcholine receptors in neuropathic, inflammatory, and cancer-related pain
- Meta-analysis finds minimal benefit of liposomal bupivacaine in TAP blocks for postoperative pain
- Meta-analysis shows VR reduces pain in adult ICU patients receiving conventional care
- Narrative synthesis on liposomal bupivacaine for autologous breast reconstruction pain
- Psychological interventions significantly reduce anxiety and depression in cancer pain patients compared to conventional care
- Acupuncture combined with Chinese medicine reduces cancer pain intensity compared to usual care in a meta-analysis of 884 patients
- Meta-analysis finds no overall link between chronic pain and cancer mortality but notes potential site-specific risks
- Systematic review on nocebo effect induction in chronic conditions and clinical communication
- Narrative review discusses multimodal strategies for rebound pain after extremity fracture surgery
- Meta-synthesis of nurses' perspectives on pediatric pain management reveals key themes
- Acupuncture plus usual care did not improve acute musculoskeletal pain at 1 month
- Systematic review of core acupoint strategies for acute musculoskeletal pain treatment trends
- Meta-analysis shows rTMS associated with reduced VAS and SF-MPQ scores in neuropathic pain
- Network meta-analysis compares analgesic techniques for upper GI surgery pain
- Systematic review of induction methods for pelvic inflammatory disease animal models
- Preoperative Pain Education Reduces Postoperative Pain and Postpartum Depression After Cesarean
- Auricular Acupressure With Music Therapy Reduces Labor Pain and Postpartum Depression
- Adding self-care complementary therapies to practitioner care showed no difference in pain function for Veterans
- Systematic review and meta-analysis shows nonsignificant pain reduction with XR in children
- Combined low-level laser and ultrasound therapy showed possible efficacy and safety for growing pains in children over 30 days
- Meta-analysis finds VR distraction does not reduce pain during IUD insertion but may lower anxiety
- Acupuncture and Celecoxib for Chronic Knee Pain: Genetic Factors May Influence Response
- Systematic review and meta-analysis finds pain and function improve over time in patellofemoral pain, but recovery is variable
- Systematic review of cold vs warm sodium hypochlorite irrigation for postoperative pain in root canal therapy
- Narrative review contrasts pediatric and adult pain management in emergency settings
- Oxycodone PCIA reduces visceral pain vs. sufentanil after repeat cesarean section
- Esketamine vs fentanyl for pediatric tonsillectomy pain shows comparable FLACC scores
- Meta-analysis finds rTMS improves neuropathic pain in spinal cord injury patients
- taVNS with ropivacaine block reduces chronic postsurgical pain after off-pump CABG in elderly patients
- In a cohort of 561 individuals with chronic pain, sex and gender identity influenced repeated prescription refill odds
- Overview of systematic reviews shows limited evidence for telerehabilitation and advanced physiotherapy in spinal pain, stroke
- Topical S. officinale preparations show efficacy for acute back pain, knee osteoarthritis, ankle sprains, and myalgia versus placebo
- Rotational effleurage and connective tissue massage reduced labor pain compared to routine care in primiparous women
- Meta-analysis shows floating needle therapy improves postpartum pain and incontinence outcomes in China
- Albanian Version of Neck Disability Index Demonstrates Strong Psychometric Properties in Neck Pain Cohort
- Observational cohort study links early-life adversity to smaller caudate volumes in children with enduring pain
- Case report of semi-implantable IDDS for advanced cancer pain in three patients
- Topical anesthesia reduces catheter-related bladder discomfort and urethral pain after ureteroscopy lithotripsy in male patients
- Systematic review of neuropathic pain trials reveals high prevalence of restrictive exclusion criteria
- Chronic pain linked to 7.5-fold increase in severe depressive symptoms in UK Biobank analysis
- Mobile app engagement and perceived usefulness in adult primary care patients with chronic pain
- Palm stimulator and cartoon reduce pain and fear during IV catheterization in children aged 5-12
- Thoracic spine manipulation improves pain and function in patients with neck pain compared to sham or alternative treatments
- Cross-sectional study finds brain structure alterations in chronic pain and depression
- Systematic review finds limited evidence for antibiotics in low back pain with Modic changes
- AI applications in acute care showed potential but face significant implementation challenges
- Systematic review finds 54.8% of Indian women with reproductive morbidities seek treatment
- Percutaneous auricular VNS linked to blood pressure reduction in hypertensive chronic pain patients
- Marburg Heart Score and INTERCHEST show modest discrimination comparable to standard protocol for acute chest pain triage
- Systemic inflammation mediates links between sleep, obesity, and musculoskeletal pain but not consistently for psychological factors
- Network meta-analysis compares 155 analgesic regimens for pain after knee and hip arthroplasty
- Federated meta-analysis validates HEART score performance for chest pain risk stratification in EDs
- Self-supervised AI model shows feasibility for detecting myofascial pain in small ultrasound study
- Survey finds 94% of cancer patients willing to try acupuncture for symptom relief
- Nociceptor hypostimulation shows superior long-term benefit for chronic cervical pain in small RCT
- Pilot RCT finds mindfulness intervention feasible for chronic pain in cancer survivors
- Oliceridine PCA non-inferior to sufentanil for knee arthroplasty pain, with lower nausea and vomiting
- Animated video reduces pain and improves satisfaction during transperineal prostate biopsy in RCT
- Retrospective study finds higher sexual problem rates in females with hEDS versus chronic pain controls
- CDC Updates Clinical Practice Guideline for Prescribing Opioids for Pain
- Observational report describes high chronic pain prevalence among U.S. adults
- Spinal cord injury linked to altered cortical excitability response to repeated tDCS
- Genetic study identifies 375 shared loci between major depression and multisite chronic pain
- Symptom burden explains most variance in pain intensity for unexplained myofascial neck/shoulder pain
- Post-thyroidectomy rehabilitation exercise improves swallowing QoL but increases early pain in single-center RCT
- Progressive Muscle Relaxation May Reduce Pain and Improve Sleep After Open Heart Surgery
- Antibiotic duration and type associated with chronic post-amputation pain in military cohort
- Acupuncture and massage reduced pain in AYA cancer patients in small RCT subgroup analysis
- Hypnotic cognitive therapy reduces pain intensity in adults with spinal cord injury
- Liposomal bupivacaine, nerve blocks compared to lidocaine for skin graft donor site pain in burn patients
- Secondary analysis identifies possible mediators for chronic pain treatments in Veterans
- VR application reduced pain and increased comfort after thyroid or parathyroid surgery in small RCT
- Mini-review summarizes AI applications for cancer pain assessment and management
- Narrative review describes bidirectional relationship between sarcopenia and pain in older adults
- Meta-analysis finds opioid-free anesthesia improves postoperative recovery versus opioid anesthesia
- Southeastern US states show highest arthritis-related severe joint pain and inactivity
- Facial micro-movements correlate with erratic heart rate during pressure pain tasks in healthy individuals
- Affective touch intervention improves existential distress and quality of life in advanced cancer patients
- Stabilization exercise shows moderate effect on dynamic balance versus conventional PT in chronic lumbopelvic pain
- Qualitative study identifies themes influencing adherence to foot strengthening in older adults
- Perineural dexamethasone extends analgesia duration in upper limb surgery blocks versus bupivacaine alone
- Mobile App with Contingency Management Improves Pain Outcomes in Adults with NF1
- Anodal tDCS of left motor cortex reduces experimental thermal pain in healthy adults
- Opioid-sparing PCA non-inferior to opioid PCA for pain after total knee arthroplasty
- Combined Versus Deep Serratus Anterior Plane Block Shows No Difference in VATS Postoperative Pain
- Pain Neuroscience Education shows short-term benefit for PTA student attitudes, not sustained at 3 months
- Ketamine may reduce positional pain more than dexmedetomidine or nerve block in femur fracture patients
- Single-shot regional anesthesia likely reduces early pain and opioid use in rib fracture patients
- Phenotype-based pain management in RA patients shows improved outcomes in retrospective cohort
- Dual histamine blockade reduces filgrastim-associated bone pain in breast cancer patients
- Virtual reality reduces intraoperative anxiety and pain in adult oral surgery patients
- Meta-analysis finds nausea in 24% and abdominal pain in 20% of RA patients on methotrexate
- SMS education reduces moderate-to-severe pain (18% vs 38%) in pediatric thoracic surgery patients
- Photobiomodulation reduces severe oral mucositis (RR 0.46) and pain (RR 0.35) in head and neck cancer patients
- Ketamine in Orthopedic Trauma: Potential to Reduce Pain and Opioid Use
- Guided Breathing VR Reduces Opioid Use Post-PTBD in Cancer Patients by 64%