Mast cell activation mediates heart failure and cardiomyopathy through diverse signaling and inflammatory pathways
Mast Cell Activity Linked to Heart Failure and Cardiomyopathy
This narrative review explores the role of cardiac mast cells in heart failure and cardiomyopathy. The authors synthesize evidence that mast…
New research explores how mast cells in the heart may drive heart failure and cardiomyopathy through various inflammatory and signaling path…
Caffeine exposure is associated with higher anxiety scores but no clear effect on depressive symptoms
Caffeine intake shows no clear effect on depressive symptoms
This meta-analysis of 668 participants evaluated the impact of caffeine on anxiety and depressive symptoms. The analysis found no clear evid…
New data shows that caffeine does not reliably change symptoms of depression, but it may increase feelings of anxiety in some people.
Glutathione metabolism acts as a homeostatic orchestrator to regulate browning in fresh-cut produce
Glutathione Metabolism May Help Prevent Browning in Fresh Produce
This mini-review explores the role of glutathione (GSH) metabolism in regulating the browning of fresh-cut produce. The authors synthesize e…
New research suggests that glutathione does more than just fight oxidation; it may actively manage how fresh-cut fruits and vegetables stay …
Oral vitamin D supplementation improves specific metabolic syndrome parameters but shows inconsistent effects on blood pressure
Vitamin D Supplementation Shows Mixed Results for Metabolic Syndrome
This narrative synthesis of 8 trials involving 634 adults with metabolic syndrome found that oral vitamin D consistently increased serum 25(…
Vitamin D supplements may improve some markers of metabolic syndrome, but results for blood pressure and cholesterol remain inconsistent.
GLP-1 receptor agonists provide additional weight loss in various stages of bariatric surgery patients
GLP-1 Medications May Enhance Weight Loss After Bariatric Surgery
This meta-analysis of 27 studies evaluates GLP-1 receptor agonists in patients undergoing metabolic and bariatric surgery. The analysis find…
New data shows that GLP-1 medications can provide additional weight loss at different stages following metabolic and bariatric surgery.
Non-basic oral sensations show varied mechanistic confidence but low food-matrix translation confidence
Scientists map the complex science behind how we taste food
This integrative critical review evaluates the mechanisms and food-matrix translation of ten non-basic oral sensations. While some sensation…
New research identifies the specific biological pathways for sensations like cooling, tingling, and the fatty feel of food in our mouths.
Whey proteins provide rapid aminoacidemia and muscle protein synthesis with limited clinical evidence for other effects
Whey proteins show promise for muscle growth and blood sugar
This narrative review examines the biochemical and physiological properties of whey proteins. The authors conclude that whey proteins provid…
Whey protein may help build muscle and manage blood sugar levels after eating, though some health benefits still need more human testing.
Unhealthy food environments and ultra-processed foods contribute to obesity and related cardiometabolic diseases
Food Environments Linked to Obesity and Type 2 Diabetes
This narrative review examines how food environment factors like accessibility and affordability influence the consumption of ultra-processe…
Unhealthy food environments and ultra-processed foods are linked to serious conditions like insulin resistance, heart disease, and chronic k…
Short-chain fatty acids and intestinal macrophages modulate metabolism in metabolic syndrome and obesity
Short Chain Fatty Acids May Help Manage Metabolic Syndrome
This narrative review explores how short-chain fatty acids (SCFAs) like butyrate, acetate, and propionate influence intestinal macrophage im…
Short-chain fatty acids like butyrate may influence how the body handles inflammation and metabolism in people with obesity and insulin resi…
Continuity of nutrition care for older medical inpatients shows inconsistent outcomes during hospital to home transition
Continuity of Care May Help Malnourished Patients After Hospital Discharge
This mini review examines the impact of continuity of nutrition care on outcomes for older medical inpatients with malnutrition during the t…
New research highlights the need for consistent nutritional support for older patients moving from hospital care to home life.
High prevalence of vitamin B12 deficiency in South Asian pregnant women suggests risk for adverse outcomes
Vitamin B12 deficiency is common among pregnant women in South Asia
This narrative review examines the prevalence of vitamin B12 deficiency in pregnant women in South Asia and its association with maternal an…
Up to 70% of pregnant women in South Asia may have low vitamin B12, a finding that could impact both mother and baby health.
Alcohol consumption is associated with a 1.809 odds ratio for gout and hyperuricemia risk
Alcohol consumption linked to higher risk of gout and hyperuricemia
This meta-analysis of cross-sectional, cohort, and case-control studies examines the link between various beverage consumption and gout. The…
Drinking alcohol may increase your risk of developing gout and hyperuricemia, a condition marked by high levels of uric acid in the blood.
All Nutrition & Obesity Medicine Articles
- Mast cell activation mediates heart failure and cardiomyopathy through diverse signaling and inflammatory pathways
- Glutathione metabolism acts as a homeostatic orchestrator to regulate browning in fresh-cut produce
- Caffeine exposure is associated with higher anxiety scores but no clear effect on depressive symptoms
- Oral vitamin D supplementation improves specific metabolic syndrome parameters but shows inconsistent effects on blood pressure
- GLP-1 receptor agonists provide additional weight loss in various stages of bariatric surgery patients
- Whey proteins provide rapid aminoacidemia and muscle protein synthesis with limited clinical evidence for other effects
- Non-basic oral sensations show varied mechanistic confidence but low food-matrix translation confidence
- Short-chain fatty acids and intestinal macrophages modulate metabolism in metabolic syndrome and obesity
- Continuity of nutrition care for older medical inpatients shows inconsistent outcomes during hospital to home transition
- Alcohol consumption is associated with a 1.809 odds ratio for gout and hyperuricemia risk
- High prevalence of vitamin B12 deficiency in South Asian pregnant women suggests risk for adverse outcomes
- Unhealthy food environments and ultra-processed foods contribute to obesity and related cardiometabolic diseases
- Home nutrition support improves quality of life in adults during first 4 months of treatment
- Institutional gatekeeping of food and beverage marketing impacts marketing presence in schools and youth sports
- Beetroot-derived nitrate and watermelon with citrulline reduce delayed onset muscle soreness at 24 and 48 hours
- Calcium and vitamin D supplementation show small BMD increases but no impact on growth in children
- Culinary medicine improves cooking confidence and self-efficacy but shows inconsistent results for clinical markers
- Flash-heating of expressed human milk preserves nutritional components and ensures microbiological safety for infant feeding
- Vitamin C supplementation may reduce psychotic symptoms in patients with schizophrenia
- Protein Plus Resistance Training Adds 2.63 kg Bench and 7.40 kg Squat Strength in Young Adults
- Gut microbiota and probiotic-derived bioactive metabolites may offer therapeutic potential for metabolic disorders
- SMILE Pro provides more accurate refractive cylinder outcomes than standard SMILE for myopic astigmatism
- Systems biology frameworks may improve the translation of protein and amino acid supplement efficacy
- Food literacy assessment tools commonly incorporate skills, knowledge, behaviors, and attitudes as core domains
- Selenium Shows Inconclusive Mucositis Benefit in Cancer Therapy, Exploratory Toxicity Reduction
- Fragmented evidence exists for exercise and nutritional interventions in managing sarcopenic obesity in older adults
- StEP program promotes Breastfed-High dietary patterns to mediate lower weight-for-age scores in infants
- Multimodal machine learning models using body composition analysis show good performance predicting colorectal cancer complications
- High carbohydrate intake significantly increases skeletal muscle glycogen in recreationally active and endurance trained athletes
- Impact of Vitamin D Carotenoids and Fatty Acids on Coronary Heart Disease Risk
- Impact of Excess Weight on Executive Function in Adolescent Populations
- Mazdutide shows dose-dependent weight reduction and HbA1c reduction in patients with obesity and type 2 diabetes
- Anti-obesity medications during weight maintenance reduce body weight and improve cardiometabolic risk factors
- One anastomosis gastric bypass provides durable weight loss and metabolic improvements over 15 years
- High-definition liposuction is safe and effective across diverse patient populations
- Comparative Analysis of Plant and Animal Protein Sources on Cardiometabolic Health
- Nutritional support may reduce infection risks and improve outcomes in bone infections
- Exercise snacks significantly improve cardiorespiratory fitness in sedentary individuals with a Hedges' g of 1.24
- Maternal gut microbiome and diet influence offspring cardiometabolic programming and metabolic resilience
- Enteral nutrition interruption is common in critically ill patients and reduces energy adequacy
- Loneliness and problematic digital media use correlate with poor eating and sleep behaviors in adolescents
- Phospholipid concentrations in human milk vary across colostrum, transitional, and mature milk stages
- Dietary interventions and gut microbiota modulation may improve cardiometabolic health in older adults
- Post-weigh-in feeding and rehydration impact body mass regain in combat sports athletes
- Higher TyG-BMI scores are associated with increased risk of incident type 2 diabetes
- Higher sugar-sweetened beverage consumption is associated with increased likelihood of ADHD symptoms in children
- Healthyer dietary patterns and physical activity may improve renal and metabolic outcomes in type 2 diabetes
- Sarcopenic obesity is longitudinally associated with impaired physical function and increased mortality in older adults
- Creeping fig polysaccharides exhibit potential anti-colitis, anti-obesity, and immunomodulatory activities in preliminary reviews
- Integrated food supplementation and behavioral counseling protocol for maternal and infant malnutrition in Guatemala
- Metabolomics profiling identifies amino acid and lipid metabolism alterations in patients with diabetes mellitus
- Impact of Time-Restricted Eating on Gut Microbiota Diversity in Overweight and Obese Adults
- Combination therapy of erythromycin and metoclopramide increases feeding success in critically ill patients
- Coumarins and derivatives may protect musculoskeletal health by modulating inflammatory and oxidative mediators
- Quercetin immunity research surges, mapping review finds 12 thematic clusters
- Aging leads to mixed gut hormone changes and altered appetite responses in older adults
- NADH shows strongest cognitive improvement while NAD+ precursors fail to improve perceived fatigue or sleep
- Nut and seed press cakes provide higher protein and lower fat than whole nuts
- Liposuction vs Conservative Therapy for Pain Management in Patients with Lipoedema
- Survodutide Improves Beta Cell Function and Insulin Sensitivity in T2D and Obesity
- Acute caffeine supplementation improves vigilance and cognitive performance during sleep deprivation in military personnel
- Plant-based food biomarkers face significant analytical and biological barriers to clinical application
- Higher adherence to MedDiet and DASH associated with better executive function in aging populations
- Polyphenols modestly reduce post-exercise soreness, but objective recovery evidence remains uncertain
- Intravenous vitamin C associated with reduced mortality in patients with sepsis and septic shock
- Balanced-Pareto food reallocation reduces metabolic syndrome burden and greenhouse gas emissions in 182 countries
- AI-based fat segmentation achieves 0.97 Dice score and is 99% faster than manual methods
- Semaglutide and Phentermine-Topiramate Lead Pediatric Weight Loss
- Semaglutide reduces NT-proBNP levels and heart-failure hospitalization in adults with HFpEF and obesity
- Comparative Efficacy of GLP-1 Receptor Agonists for Adolescent Obesity and Type 2 Diabetes
- Structured monitoring improves intestinal mucosa histology in Celiac Disease patients on gluten-free diets
- Preoperative carbohydrate beverages reduce hospital stay and time to first defecation in colorectal surgery patients
- Polyphenol supplementation combined with resistance training shows small and statistically uncertain improvements in muscle strength
- High-risk adiposity and inflammation trajectories correlate with significantly increased risk of incident Type 2 Diabetes
- Mediterranean diet associated with lower BMI and systolic blood pressure in children with obesity
- Higher PNI scores are associated with lower short-term mortality in patients with sepsis
- Creatine Supplementation and Resistance Training for Enhancing Muscle Strength in Older Adults
- Protein supplementation added to exercise improves grip strength and muscle mass in older adults with sarcopenia
- Enteral nutrition shows greater clinical effectiveness than low residue diet in ulcerative colitis
- Nutrition and hydration education improves sports nutrition knowledge and short-term hydration in youth athletes
- Higher AMY1 gene copy number is associated with improved insulin resistance and postprandial glucose response
- Dairy proteins favor acute metabolic markers while pea protein may favor gut microbiota profiles
- No specific exercise modality significantly reduces gestational weight gain in pregnant women
- Lutein, beta-carotene, and vitamin D are associated with lower risks of several gynecological and breast cancers
- Exclusive human milk diet reduces odds of death before discharge in premature and low birthweight infants
- Habitual tea consumption is associated with 13% lower hypertension risk in cohort studies
- Fenugreek modestly raises total testosterone in men, but evidence is very low certainty
- Multidimensional biomarkers of nutritional, inflammatory, and metabolic status identify risk in geriatric hip fracture patients
- Probiotic supplementation for 12 weeks or more shows a non-significant trend toward clinical improvement in at-risk populations
- Zebrafish platform proposed to bridge natural product sleep research gaps
- Ninjin’yoeito attenuates postoperative Prognostic Nutritional Index decline in patients with oral squamous cell carcinoma
- Prediction models for prolonged air leak show variable discriminatory power ranging from 0.644 to 0.914
- Gastrointestinal endometrioid adenocarcinoma presents as rare metastatic-like lesions in the rectosigmoid and sigmoid colon
- Sarcopenia Assessment Modalities and Mortality Risk Prediction in Patients with Liver Cirrhosis
- Kampo medicine may support appetite and metabolic resilience in patients with sarcopenia
- 6-gingerol improves hepatic lipid profiles and glucose metabolism in animal models of NAFLD
- Bariatric surgery may not always result in parallel updates to perceived body image
- Nutrition phenotype framework provides a structured approach for personalized nutrition care in inflammatory bowel disease
- Nutrition-related laboratory biomarkers provide risk stratification for geriatric patients with hip fractures
- Chitosan, cellulose, and hemicellulose based edible interfaces provide controlled release of bioactive compounds for food preservation
- Curcumin-piperine combination shows superior neuroprotection in preclinical models, but clinical data lacking
- Lacto-fermented vegetables may improve gastrointestinal symptoms, cardiometabolic risk factors, and gut microbial function
- Green-MED diet with Mankai intake significantly increases serum folate levels compared to standard diets
- Eicosapentaenoic acid evidence is most developed for depressive symptoms rather than brain aging
- Mediterranean diet with wine consumption associated with lower mortality and cardiovascular disease risk
- Dietary components like polyphenols and omega-3 fatty acids may modulate the inflammatory environment in endometriosis
- Whey protein ranked first for lean body mass gains during supervised resistance training
- Adding aerobic exercise to energy restriction reduces inflammatory biomarkers in individuals with overweight or obesity
- Steviol glycosides serve as sucrose substitutes, but metabolic benefits need human validation
- Sourdough bread evidence insufficient to support glycemic benefit over yeast-fermented bread
- Mediterranean diet adherence is associated with reduced risk of several site-specific cancers and mortality
- Ketogenic diets reduce seizures in 69% of refractory epilepsy patients in Latin America
- Exercise training prevents 45.7% of fat-free mass loss during calorie restriction in overweight and obese individuals
- Abdominoplasty complications show no significant difference between patients with and without history of metabolic surgery
- Ketogenic diet therapy yields 42.82% seizure reduction in drug-resistant epilepsy
- GLP-1 receptor agonists associated with favorable cardiovascular outcomes in adults with Type 2 Diabetes
- Saffron provides the most coherent signal for fluoxetine-associated sexual dysfunction among plant-derived bioactives
- Enteral nutrition in neurocritical patients shows feeding intolerance rates between 46.38% and 62.0%
- Monkey orange fruit shows high acidity, rich nutrients, but bio-accessibility remains poorly characterized
- Mindfulness Apps Reduce Binge and Emotional Eating in Adults
- Pretreatment Creatinine to Cystatin C Ratio Predicts Survival in Gastrointestinal Cancers
- Marine compounds from Mexican Pacific Sargassum may protect against AMD progression in preclinical models
- Perioperative tube-fed enteral nutrition management for esophageal cancer involves nine key clinical aspects
- Early enteral nutrition reduces mortality in randomized trials of patients with traumatic brain injury
- New IOL calculation formulas and adjustable technologies improve refractive outcomes in post-RK cataract patients
- Fermented dairy consumption and reduced risk of asthma or wheeze in children
- Loss-of-function ABCG5/ABCG8 mutations firmly establish sitosterolemia etiology in systematic review
- Sarcopenia is associated with poorer survival and higher complication rates across multiple cancer types
- Postoperative radiotherapy improves survival and reduces recurrence in resected ESCC
- Time-restricted eating reduces body weight, BMI, and HbA1c in adults with type 2 diabetes
- Lactiplantibacillus plantarum supplementation improves exercise performance and recovery through specific probiotic strains
- Ultra-processed food intake correlates with 12% higher risk of digestive system cancer
- Communal dining is associated with higher nutritional intake and lower depression risk in older adults
- Whey protein combined with structured exercise may support muscle health and metabolic regulation in older adults
- Acute caffeine supplementation improves sprint performance and passing accuracy in rugby players
- Precision synbiotic reduces URTI incidence from 85.4% to 55.4% in toddlers
- Orforglipron tablets and capsules are bioequivalent across six dose levels in adults with obesity
- Incretin-based weight loss lower in type 2 diabetes trials, but confounded by demographics
- Probiotics in functional pet foods face challenges regarding host specificity and processing stability
- Dextrins may increase circulating GLP-1 concentrations and satiety in adults with limited evidence certainty
- Caffeine shows no ergogenic effect on sport-specific or physical performance in female volleyball players
- Pitaya by-products show antioxidant, anti-inflammatory, hypolipidemic, and hypoglycemic potential in systematic review
- Probiotic strains CBA-L74 and SS-K12 significantly reduce acute otitis media incidence in children
- Sugar sweetened beverages and orange juice are associated with increased risk of several cancer types
- Citrus bergamia nutraceuticals significantly reduce body weight and BMI in patients with obesity
- Adverse Childhood Experiences are associated with increased odds of metabolic syndrome and hyperglycemia
- Plant-based dietary patterns reduce C-reactive protein concentration by 1.13 mg/L compared to omnivorous diets
- Preoperative carbohydrate loading improves pediatric anesthesia cooperation and reduces postoperative nausea and vomiting
- Roux-en-Y gastric bypass and sleeve gastrectomy produce distinct and durable post-operative hormonal profiles
- Mediterranean-based diets may offer superior efficacy over traditional dietary advice for irritable bowel syndrome
- Gut microbiota may influence metabolic response to GLP-1 receptor agonists in obesity and type 2 diabetes
- Food additives in ultra-processed foods impact gut microbiome and metabolic function in experimental models
- Bovine milk fortifiers non-inferior to human milk fortifiers for NEC and sepsis in pre-term newborns
- Ketogenic diet may improve insulin sensitivity, lipid profiles, and glycemic control in patients with metabolic syndrome
- Alginate oligosaccharides function as potential modulators for sodium reduction in coated and fried food systems
- Functional sweet tea components may mitigate metabolic risks including hyperglycemia and liver disease
- Dietary management and hypoallergenic formulas impact micronutrient status and growth in children with cow's milk allergy
- In vitro models require improved motility and enzymatic activity to simulate infant intestinal digestion accurately
- Higher weight-adjusted waist index (WWI) correlates with increased all-cause and cardiovascular mortality risks
- Probiotic fermentation of herbal residues may enhance bioactive compounds and gut-liver axis for obesity
- Intermittent fasting combined with resistance training produces similar adaptations to resistance training alone
- Whey protein may mitigate body weight loss and preserve fat-free mass after bariatric surgery
- Antioxidants improve oxidative stress and neuropsychiatric symptoms but not cognition in Alzheimer's
- Impact of Body Mass Index Categories on Outcomes in Patients with DLBCL
- Circadian misalignment associated with increased risk of osteoporosis, sarcopenia, and osteoarthritis
- Enteral immunonutrition reduces infectious complications in patients undergoing surgery for colorectal cancer
- Point-of-care ultrasound supports diverse bedside applications in pediatric enteral nutrition management and assessment
- Multidisciplinary cooperation nutrition management processes provide a standardized framework for critically ill patient care
- Low PNI and GNRI correlate with poorer survival in elderly patients with early gastric cancer
- Digital health technologies offer varying levels of clinical readiness for managing sarcopenia in hemodialysis patients
- Protein plus probiotic supplementation improves physical performance with Hedges g of 0.45 in adults
- Med-Diet LLM agent outperforms general purpose models in generating dietary plans for noncommunicable diseases
- EIP-DGI framework identifies three stages of dietary guideline impact from initial communication to behavior
- 58% of women with PCOS have vitamin D deficiency, meta-analysis finds
- LGI and LGL diets reduce body weight, lipid profiles, and inflammatory markers in humans
- Curcumin as a theranostics agent: intrinsic fluorescence and protein affinity offer dual diagnostic and therapeutic potential
- Ultra-processed food consumption is associated with metabolic syndrome, cardiovascular risk, and allergic diseases in children
- Beta-alanine supplementation improves time to exhaustion in women with a pooled effect of SMD 0.49
- Synthetic food production technologies offer a promising resource for resilient global food systems
- Exercise interventions may improve adiposity and physical function in middle-aged or older adults with sarcopenic obesity
- High glycemic variability in ICU patients linked to 2.29-fold higher mortality risk
- Fish consumption increases vitamin D levels by 4.08 nmol/L in children across randomized trials
- Food insecurity linked to poorer diet and higher obesity risk in older adults
- Vitamin D's role in antifungal immunity remains uncertain due to species differences
- Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
- Semaglutide associated with 35.2% of weight loss as lean mass versus 26.2% with lifestyle interventions
- NAD+ repletion via NMN or NR shows context-dependent effects on muscle stem cell homeostasis and sarcopenia
- Commercial preterm formulas with glucose polymers and reduced lactose show higher necrotizing enterocolitis rates than breast milk
- Modulating endogenous PYY expression offers a theoretical basis for individualized obesity management strategies
- Vitamin D improves strength and reduces injuries in dancers, while iron lowers anemia prevalence
- Insulin degludec/liraglutide ranks highest for HbA1c reduction with SUCRA value of 89.4%
- Tirzepatide maximum tolerated dose leads weight reduction ranking in obesity network meta-analysis
- Cultured meat production requires integrated cell selection and regulatory compliance for complex tissue replication
- Eating later in the biological day is associated with impaired glucose regulation and reduced insulin sensitivity
- Nutrient and metabolite interventions for neurodegenerative diseases show inconsistent clinical translation
- Metabolic and bariatric surgery significantly reduces plasma Fetuin-A levels in patients with obesity
- GLP-1 agonists show short-term metabolic benefit in PCOS but reproductive effects remain uncertain
- Mediterranean diet triples metabolic syndrome reversal rate vs low-fat diet in interim trial
- Preoperative GLP-1 agonists yield moderate weight loss before bariatric surgery, meta-analysis finds
- Higher EAT-Lancet diet adherence linked to lower risks of depression, anxiety, stroke, and dementia in observational cohorts