RELAX digital intervention reduces anxiety and repetitive negative thinking in pregnant individuals
Digital tool helps pregnant people manage anxiety and worry
This Phase 2b randomized clinical trial of 268 pregnant individuals found that the RELAX digital intervention significantly reduced anxiety …
A new digital program helps pregnant people reduce anxiety and repetitive negative thinking during and after pregnancy.
Generative AI maternal health chatbot did not improve anxiety or depression at 12 months
AI Chatbot Does Not Reduce Anxiety for New Mothers
This randomized clinical trial of 400 English-speaking pregnant or postpartum individuals found no significant difference in anxiety or depr…
A study of 400 new mothers found that using a generative AI chatbot did not improve anxiety or depression scores compared to reading childre…
Cognitive behavioral therapy is associated with lower fatigue, anxiety, and depression in rheumatoid arthritis
Cognitive behavioral therapy may lower fatigue and anxiety in RA
This meta-analysis of 1,538 adults with rheumatoid arthritis found that cognitive behavioral therapy (CBT) is associated with lower levels o…
Cognitive behavioral therapy may help adults with rheumatoid arthritis manage heavy feelings of fatigue, anxiety, and depression.
School-based nutrition programs in Greece and Cyprus show favorable changes in BMI and dietary intake
School Nutrition Programs Show Potential for Better Student Health
This scoping review of 21 articles examines school-based nutrition interventions in Greece and the Republic of Cyprus. The review found favo…
School-based nutrition programs in Greece and Cyprus show promise in improving student diet, activity levels, and knowledge.
Gut microbial metabolites modulate neural homeostasis and influence neuroinflammation in several neurological and psychiatric disorders
Gut Metabolites May Influence Alzheimer's and Parkinson's Disease
This narrative review explores how gut microbial metabolites, including short-chain fatty acids, tryptophan metabolites, and bile acids, inf…
Gut microbes produce metabolites that may influence brain health and impact conditions like Alzheimer's, Parkinson's, and chronic insomnia.
Web-Based Mindfulness Program Lowers Depression Relapse in Pregnant Women
Web-Based Mindfulness Program Lowers Depression Relapse Risk for Moms
A web-based mindfulness programme cut depressive relapse risk in pregnant women with recurrent depression, compared with usual care.
A new web-based mindfulness program may help mothers with a history of depression reduce their risk of relapse during the first six months a…
AINAR game intervention associated with greater needle fear reduction in blood donors
AI game helps reduce needle fear for blood donors
This randomized controlled trial of 3000 whole blood donors evaluated the AINAR artificial intelligence-based game for needle anxiety. While…
A new AI game helps blood donors manage needle fear, though more research is needed to confirm its impact on fainting during the donation pr…
Clozapine serum and plasma concentrations correlate with efficacy and safety in schizophrenia spectrum disorders
Clozapine Levels Linked to Better Outcomes in Schizophrenia Treatment
This meta-analysis examined the relationship between clozapine and norclozapine concentrations and various clinical outcomes in patients wit…
New data suggests specific clozapine levels may relate to better symptoms and safety for people with schizophrenia spectrum disorders.
Mindfulness-based cognitive therapy significantly reduces psychological distress, depression, and anxiety in cancer patients
Mindfulness Therapy Reduces Distress and Fatigue in Cancer Patients
This meta-analysis of 11 RCTs involving 1122 adults with cancer found that mindfulness-based cognitive therapy (MBCT) significantly reduced …
Mindfulness-based cognitive therapy can significantly lower depression, anxiety, and fatigue for adults living with various types of cancer.
One in five outpatients drops out of individual CBT for schizophrenia, moderator findings exploratory
One in Five May Drop Out of CBT for Schizophrenia
This secondary analysis of a systematic review and meta-analysis estimates that approximately one in five participants drop out of individua…
About 1 in 5 people in face-to-face CBT for schizophrenia may stop attending, a new analysis finds, with wide variation across studies.
Prenatal Exercise and the Risk of Postpartum Depression in Pregnant Women
Prenatal exercise may lower the risk of postpartum depression
A meta-analysis of 2,231 women suggests that higher levels of prenatal exercise may correlate with a lower incidence of postpartum depressio…
New data suggests that regular exercise during pregnancy could help lower the risk of developing postpartum depression.
DTI-ALPS index markedly lower in schizophrenia than in healthy controls, suggesting glymphatic dysfunction
Brain Waste-Clearing System May Work Less Well in Schizophrenia
This meta-analysis examined the DTI-ALPS index, a surrogate marker of glymphatic function, in patients with schizophrenia versus healthy con…
A brain scan marker tied to how the brain clears waste was notably lower in people with schizophrenia than in healthy people.
All Psychiatry Articles
- Cognitive behavioral therapy is associated with lower fatigue, anxiety, and depression in rheumatoid arthritis
- Generative AI maternal health chatbot did not improve anxiety or depression at 12 months
- RELAX digital intervention reduces anxiety and repetitive negative thinking in pregnant individuals
- School-based nutrition programs in Greece and Cyprus show favorable changes in BMI and dietary intake
- Gut microbial metabolites modulate neural homeostasis and influence neuroinflammation in several neurological and psychiatric disorders
- AINAR game intervention associated with greater needle fear reduction in blood donors
- Web-Based Mindfulness Program Lowers Depression Relapse in Pregnant Women
- Prenatal Exercise and the Risk of Postpartum Depression in Pregnant Women
- Mindfulness-based cognitive therapy significantly reduces psychological distress, depression, and anxiety in cancer patients
- DTI-ALPS index markedly lower in schizophrenia than in healthy controls, suggesting glymphatic dysfunction
- Dopamine partial agonist antipsychotics show no significant impact on suicide outcomes in schizophrenia trials
- Non-invasive brain stimulation significantly increases peripheral BDNF levels and reduces depressive symptoms in MDD
- Clozapine serum and plasma concentrations correlate with efficacy and safety in schizophrenia spectrum disorders
- A 3-factor solution for the Responses to Positive Affect scale outperforms the 2-factor solution
- Metacognition linked to insight in psychosis, but only self-reflection tasks show moderate association
- One in five outpatients drops out of individual CBT for schizophrenia, moderator findings exploratory
- Three-tier surveillance framework addresses resource limitations for Hantavirus and hemorrhagic fever with renal syndrome
- Evidence for restricted and repetitive behaviors in autism is more prevalent in early childhood
- Depression and anxiety prevalence in Behđet's disease reaches approximately 47.44% and 48.48% respectively
- Sodium lactate challenges provoke panic, but exercise hyperlactatemia seldom does, review argues
- Digital health innovations offer accessibility benefits but require careful management of environmental and social risks
- Digital phenotyping enables real-time mental health monitoring and risk prediction in people with diabetes
- Narrative review links adolescent idiopathic scoliosis to anxiety and depression via stress, pain, and body image pathways
- Electrical stimulation improves clinical response and reduces depressive symptom severity in patients with depression
- TPOAb positivity is associated with a 1.52 relative risk of perinatal depression in females
- MBSR matches escitalopram for GAD anxiety, with high-certainty evidence
- Active rTMS to the DLPFC for patients undergoing major abdominal surgery
- Evaluating Digital and In-Person Interventions for Migrant Mental Health in Italy
- rTMS combined with sertraline improves depressive symptoms and cognitive scores in adolescents
- Transcranial magnetic stimulation modulates transcriptomic and connectomic changes in treatment-resistant depression
- Transdiagnostic psychological mechanisms like hopelessness and repetitive negative thinking associate with suicidal ideation in students
- Tunisian Guideline Offers 96 Evidence-Based Recommendations for Autism Care
- Shared gray matter volume reductions in ventromedial prefrontal cortex and insula across schizophrenia, MDD, and AUD
- Systems-oriented One Health approach addresses structural and social barriers in family poultry disease control
- Repetitive negative thinking serves as a transdiagnostic bridge between childhood trauma and depression
- Dance and movement therapies linked to improved depression and anxiety symptoms, but evidence is heterogeneous
- Acupuncture Plus Antidepressants Lowers HAMD Scores in Chinese Depression Patients
- Mosque-based, culturally congruent, and faith-integrated interventions show good acceptability for Muslim American women's mental health
- Green exercise may improve psychological well-being and reduce stress in children and adolescents
- Autistic features like sensory sensitivities and interoceptive differences shape eating disorder experiences and recovery
- Active inference and free energy principles provide a framework for understanding psychopathology as projection disorders
- Verbal de-escalation techniques improve staff confidence and reduce patient agitation in workplace violence settings
- Daridorexant considered appropriate for chronic insomnia across heterogeneous clinical profiles, consensus says
- Training may slightly boost nurses' sexual harassment knowledge and skills
- Medical cannabis may have little to no clinically meaningful effect on insomnia sleep quality
- AI tools demonstrate high diagnostic accuracy for Autism Spectrum Disorder with pooled AUC of 0.936
- Evidence mapping for brain injury mental health and substance use shows low methodological quality
- Social isolation and loneliness are significant determinants of cognitive decline and dementia risk in older adults
- Stem Cell EVs Improve Autistic-Like Behaviors and Lower IL-6 in Animal Models
- Non-steroidal anti-inflammatory drugs are a predictably effective first-line pharmacologic therapy for canine osteoarthritis
- Reproductive coercion is associated with reduced contraceptive self-efficacy and adverse mental health outcomes
- Parent-led online CBT with therapist support increases QALYs by 0.021 in children with anxiety risk
- Higher baseline PANSS Negative scores predict 21% lower relapse risk in schizophrenia
- Music-based interventions significantly improve social communication and autism-related scale outcomes in autistic children
- AI-mediated conversational interventions reduce depression and anxiety symptoms in university students compared to low-intensity controls
- Tai Chi and Yijin Jing rank highest for reducing depression and anxiety in college students
- Fear of negative evaluation shows moderate positive association with social anxiety across 146 independent samples
- Identifying Barriers to Mental Health Treatment in Collaborative Care for Opioid Use Disorder
- Psychiatric Comorbidities in Patients Diagnosed with Dissociative Identity Disorder
- Digital psychological interventions modestly improve pain and anxiety in adolescents with chronic pain and comorbid anxiety or depression
- Daily stopping of sedation may reduce ventilator time and mortality in critically ill patients
- XR-based bullying prevention interventions show mixed evidence for long-term behavioral changes in K-12 students
- Probiotics modestly reduce depressive symptom severity in adults with clinical depression
- Clinician-supported digital mental health services significantly improve anxiety and depression symptoms in Australian consumers
- Virtual reality shows statistically significant superiority over exercise-based interventions for chronic spinal pain
- Age-specific nutritional management strategies address malnutrition and sarcopenia in liver transplant recipients
- Voice and speech biomarkers show clinical interpretability but lack evidence for validity and deployability
- Aviophobia linked to temporal and limbic epileptiform activity in narrative review
- Elicit AI tool shows promise for data extraction but lacks precision for independent systematic reviews
- Retrospective reports of pain intensity are significantly higher than daily diary reports in JFM
- Smartphone-delivered EASE and MR interventions show no significant difference in anxiety and depression
- Autism-related stigma significantly degrades quality of life across mental, physical, and social domains
- Ketamine modulates NMDA receptors and glutamate transmission for treatment-resistant depression and other psychiatric disorders
- Resting-state functional MRI reveals distinct regional homogeneity patterns in MDD, BD, and Schizophrenia
- Antidepressants combined with psychotherapy do not significantly improve depression severity in major depressive disorder
- PGx-guided antidepressants modestly increase short-term response and remission in MDD
- Increased social jetlag is associated with more severe anxiety in adolescents
- Bipolar disorder is associated with increased cerebrospinal fluid and intracranial volumes compared to controls
- Five-Element Music Therapy Impacts Psychological Wellbeing and Physiological Markers in Chemotherapy Patients
- Depression and Schizophrenia Stereotypes Differ in Warmth but Not Competence
- Self-medication of ADHD symptoms with psychoactive substances is predominantly inferred from association or motive reports
- Exercise interventions significantly improve object control, locomotor, and stability skills in children with autism
- Mass Gathering Preparedness Requires Integrated EMS and Hospital Surge Capacity
- Parent and Teacher ADHD Ratings Show Low Agreement, Kappa 0.25 Across 8,796 Youth
- FDA Approves Valium (diazepam) for Anxiety, Alcohol Withdrawal, Muscle Spasm, and Convulsive Disorders
- Aerobic exercise, whey protein, and creatine may support performance and metabolic adaptation in adolescents
- Long-term psychodynamic psychotherapy significantly reduces depressive symptoms compared to all other treatment types
- Implementation bundle reduces guideline-discordant prolonged antimicrobial use in patients undergoing cardiovascular implantable electronic device procedures
- Time-restricted eating reduces body mass and body fat percentage in adult athletes
- Early trauma may drive psychotic experiences in autism through three integrated mechanisms
- LLM-enabled AI chatbots are primarily utilized for text-based, lower-acuity, and information-oriented health purposes
- Metacognitive training improves clinical insight in schizophrenia compared to non-metacognitive targeted approaches
- AI and machine learning tools show potential for screening and managing substance use disorders
- Multidisciplinary interventions and Mediterranean diet adherence may modestly reduce BMI Z-score in pediatric obesity
- Self-compassion and reduced rumination may improve post-traumatic adaptation in individuals with depressive disorders
- Lower baseline IL-2 and IL-6 levels signal potential antidepressant treatment response in Major Depressive Disorder
- TCCWTMS yields best sleep quality improvements among Tai Chi and Baduanjin for sleep disorders
- Meliora video game therapeutic reduces GAS-7 scores by 0.63 points in major depressive disorder
- PROMATER online program aims to improve self-compassion and reduce self-criticism in pregnant women
- Intermittent and periodic fasting trigger metabolic reprogramming and enhance cellular repair and antioxidant defense
- Psilocybin shows more robust evidence for sustained effects in treatment-resistant depression than ayahuasca
- Mindfulness-Based Interventions May Improve Core ADHD Symptoms in Youth, but Heterogeneity Is High
- Music listening sessions did not improve DASS-21 scores in women undergoing artificial insemination
- Macrophage Subsets in Cardiac Disease: Complex Functions and Emerging Therapeutic Directions
- Armed conflict exposure is associated with high PTSD prevalence among civilians in Indian-administered Kashmir
- Dexmedetomidine reduces anxiety scores in adult perioperative patients especially within 24 hours postoperatively
- Childhood maltreatment is associated with specific subcortical and cortical volume changes in MDD and PTSD
- Isolated physical activity programs reduce depressive symptoms in pregnant and postpartum women
- Explainable machine learning may improve risk prediction and clinical decision-making for women with FGS and HIV
- Meta-analysis Evaluating the Correlation Between Sleep Paralysis and Clinical Anxiety Symptoms
- Lifestyle Therapy Matches CBT for Moderate-to-Severe Depression in Australian Trial
- Test anxiety affects 49.8% of medical students across various geographic regions and academic years
- Unexamined relational-proximity priors may lead to misinterpreting neurodivergent behaviors as resistance or lack of insight
- Trazodone improves sleep architecture and duration in patients with depression and sleep disorders
- IBS-M, IBS-D, and IBS-C patients report higher severity scores and lower quality of life
- Unified Protocol for Adolescents shows significant treatment effects for hyperactivity and conduct problems
- Meta-analysis finds no atypical reliance on priors in schizophrenia-spectrum psychosis
- Lumateperone adjunct therapy improves sexual functioning in patients with major depressive disorder
- Silexan shows clinically important adjusted mean value differences of over 0.2 points in MADRS
- Platelet-rich plasma shows potential for tissue repair and functional recovery in various nerve injuries
- DORAs show strongest evidence for insomnia while sedating antidepressants vary in antidepressant activity and side effects
- mHealth app-supported care pathway did not significantly reduce caregiver state anxiety in ENT surgery cases
- Higher baseline PANSS negative symptom severity associated with lower risk of symptom exacerbation
- Identified barriers and enablers provide evidence based insights for scalable health system transformation strategies
- Recurrent implantation failure worsens quality of life and raises depression, anxiety in IVF patients
- Play interventions significantly reduce anxiety and depressive symptoms in children with cancer
- Abundant research exists on sex and gender effects in obsessive-compulsive disorder despite limited evidence synthesis
- Heart rate variability parameters correlate with anxiety severity scores in adults
- Depression affects 22.2% of Black post-secondary students in North America
- Theta binaural beat therapy reduces pain scores in adults with a moderate effect size
- Ketogenic diets and intermittent fasting may improve weight, insulin sensitivity, and hepatic steatosis in MASLD
- Psychobiotic and nutritional interventions may modulate mood symptoms via gut-brain axis pathways
- Home-based and remotely supervised tDCS produces small, statistically significant improvement in Major Depressive Disorder
- Depression, distress, and fear avoidance significantly predict persistent non-specific low back pain and disability
- Barriers to mental health care for Black populations include racism, stigma, and socioeconomic determinants
- Intranasal esketamine and intravenous ketamine provide the strongest evidence for treating depressive disorders
- Depressive disorder in patients with diabetes increases all-cause mortality and metabolic complications
- Mindfulness program shows specific improvements in learning autonomy and positive affect in migrant students
- Deployment-enabling strategies offer more tractable pathways for multimodal medical AI in low-resource healthcare settings
- Trauma-focused cognitive behavioral therapy and narrative exposure therapy show strongest evidence for pediatric war-related trauma
- Corticosteroid exposure was associated with catatonia in two adolescent girls with encephalitis
- Lower income and economic inequality are associated with poorer mental health, especially in women
- Semaglutide and liraglutide are associated with the greatest weight reductions in patients with schizophrenia
- Preoperative anxiety affects 66.7% of women undergoing cesarean delivery across global settings
- Acute exercise significantly reduces state anxiety in children and adolescents across multiple modalities
- Chatbots may offer potential short-term benefits for mental health conditions based on current evidence
- ADHD doubles bruxism odds in meta-analysis of 16,348 individuals
- Evaluating Pharmacogenomic Guided Treatment Efficacy for Patients with Major Depressive Disorder
- Ketamine or esketamine may improve functional motor symptoms and dissociative seizures in functional neurological disorder
- Tai Chi ranks highest among mind-body exercises for depressive symptoms in older adults
- Aerobic exercise combined with tai chi may reduce Positive and Negative Syndrome Scale scores
- Increased Risk of Dementia Diagnosis Among Individuals Diagnosed With Bipolar Disorder
- Impact of Cognitive Behavioural Therapy on Exclusive Breastfeeding in Postpartum Depression
- Inflammatory biomarkers show inconsistent and small associations with antidepressant and ECT treatment response in MDD
- Maximal voluntary breath-holding time identifies shorter interoceptive tolerance in patients with panic disorder
- Perioperative music significantly reduces preoperative anxiety and postoperative pain in children and adolescents
- AGE levels significantly elevated in schizophrenia-spectrum disorders, meta-analysis finds
- Paliperidone ER and LAI show no significant difference in personal and social performance scores
- 5-HTR antagonists improve negative symptoms and cognition in schizophrenia, meta-analysis finds
- Physical activity cuts anxiety and depression in incarcerated individuals, meta-analysis finds
- Conventional and mind-body exercise improve symptoms and quality of life in menopausal women
- Nonpharmacological Behavior Management Strategies for Children and Adolescents with Neurodevelopmental Disorders
- Dementia prevalence 24.3% in older adults with psychotic disorders, meta-analysis finds
- Child Life Specialists reduce pain, distress, and anxiety in paediatric patients across clinical settings
- tDCS is the most efficacious standalone non-invasive brain stimulation for autism social cognition
- Electroconvulsive therapy improves symptoms in all age groups of patients with major depressive disorder
- Indigenous-developed wellbeing models emphasize holistic integration, spirituality, and collective relationality over Western approaches
- Fatty pancreas prevalence 30.5% and linked to higher pancreatitis, cancer risk
- Systemic Barriers Impede HIV Care for African Migrants
- RITA-T shows strong psychometric properties across cultures for autism screening in toddlers
- Desipramine shows large effect in adolescent MDD while other antidepressants show no significant difference
- Telecounseling significantly reduces depressive symptoms in primiparous women during the postpartum period
- tDCS combined with cognitive-behavioral interventions shows no significant benefit over sham for depressive symptoms
- Acupuncture-related stimulation improves subjective sleep quality in insomnia, but objective evidence is less secure
- Exercise and structured physical activity provide multidimensional benefits for individuals with Autism Spectrum Disorder
- Dehydration impacts physical performance, cognitive function, and mood among healthcare workers during shifts
- Virtual reality interventions significantly improve motor skills in children and adolescents with intellectual disabilities
- Higher responsiveness to verbal suggestions correlates with greater placebo symptom relief, r = 0.18
- High intensity exercise training improves dyspnoea management across multiple chronic respiratory and neuromuscular conditions
- Mentalization-based and mentalization-informed approaches may improve parental reflective functioning and cognitive reappraisal in autism
- Fermented foods pose low chemical risk but require strict raw material and processing controls
- Organic waste mismanagement supports free-roaming dog populations and increases rabies risk in endemic regions
- Problem-focused coping and meaning-making facilitate adaptive functioning in families of children with cancer
- FDA Approves Duloxetine Delayed-Release Capsules for MDD and GAD
- eMPower digital program reduced HADS total scores by 2.6 to 2.9 points over waitlist control
- Arabic Motives for Online Gaming Questionnaire shows strong internal consistency and concurrent validity
- Therapist-guided I-BA reduces depression severity more than TAU in adolescents with MDD
- Self-modeling boosts athletic performance and self-efficacy, but gains fade within a week
- Visual art therapy significantly improves global cognitive function and activities of daily living in older adults
- Microdosing psilocybin is associated with reported well-being and mental health benefits in some studies
- AI models using noncontact physiological signals achieve 81.3% accuracy for binary stress classification
- Digital interventions outperform non-digital treatments and wait-list controls for social anxiety disorder
- Specific resting-state functional connectivity alterations correlate with anhedonia severity in Major Depressive Disorder
- Administrative criteria including hospitalization and treatment changes define relapse in Major Depressive Disorder
- Misoprostol and oxytocin show comparable effectiveness for postpartum hemorrhage in Nigerian review
- Stepped-care intervention reduces PHQ-ADS scores by 6.52 points compared to care-as-usual
- Propranolol shows potential for managing various neurological diseases including PTSD, migraine, and autism spectrum disorder
- SHVASAN model aims to improve rural screening and diagnosis of asthma and COPD
- Acupuncture interventions significantly increase regional homogeneity and ALFF in the right cingulum and caudate
- Reduced cortical surface area and amygdala volume are associated with youth internalizing and externalizing disorders