Infectious Disease

All Infectious Disease Articles

• Telitacicept 160 mg plus standard therapy doubles SRI-4 response rate in adults with SLE
• Structured triage and individualized fluid therapy improve dengue management in resource-constrained settings
• Minocycline 40 mg outperforms doxycycline for rosacea in meta-analysis
• Precision-oriented resuscitation for septic shock emphasizes titrated fluid therapy and individualized vasopressor management
• Probiotics and postbiotics demonstrate anti-Candida activity by inhibiting growth, biofilm formation, and virulence genes
• Biopsychosocial determinants shape TB care outcomes across 124 studies
• Fluoroquinolone resistance acquired more frequently during TB treatment than other anti-TB drugs
• Point-of-care ultrasound supports source identification and physiologic reassessment in patients with sepsis and septic shock
• Limited clinical translation of sepsis biomarkers highlights significant gap between discovery and deployment
• Oral HPV reshapes mucosal microbial composition in a sex and population dependent manner
• H5N1 virus shows high mammary tissue tropism and significant viral shedding in dairy cattle milk
• B-cell depletion and S1P inhibitors significantly reduce mRNA vaccine binding antibody levels in immunocompromised patients
• Direct-acting antiviral therapy and diverse viral infections require comprehensive epidemiological and diagnostic strategy review
• LLM-derived embeddings outperform tabular models for end-of-therapy outcome prediction in tuberculosis patients
• Good antiretroviral therapy adherence is associated with a 6.30 odds ratio for viral load suppression
• Ervebo and Zabdeno/Mvabea vaccines show significant differences in antibody cross-reactivity to Bundibugyo virus
• Antigen delivery and immune programming are the primary hurdles for H. pylori vaccine development
• Impact of Intrawound Vancomycin on Surgical Site Infection and Outcomes in Spinal Fusion
• Capmatinib identified as a promising candidate for repurposing against Mpox via in silico screening
• Pegylated erythropoietin provides improved Hb stability and reduced dosing frequency in CKD-related anemia
• Islatravir 60 mg oral qm showed 64.3% adverse event rate compared to 77.1% in comparator
• Moxifloxacin achieves 87.0% microbiological cure in Mycoplasma genitalium compared to 61.2% for azithromycin
• Monoclonal antibodies and various vaccine platforms show potential for human metapneumovirus prevention in children
• Sensititre MYCOTB shows high diagnostic accuracy for rifampicin and isoniazid in tuberculosis isolates
• Typhoidal Salmonella pathogenesis involves a unified network of virulence determinants and metabolic proteins
• Peg-interferon add-on to nucleoside analogues achieves HBsAg loss in 8.6% of patients
• Ceftolozane-tazobactam associated with higher clinical cure rates in multidrug-resistant Pseudomonas aeruginosa infections
• No Reproducible Microbial Signature Found in Medication-Related Osteonecrosis of the Jaw
• Structured exercise improves quality of life and VO2 max in older adults with HIV
• Corticosteroids added to antiviral therapy do not improve outcomes in herpes simplex virus encephalitis
• MRSA nares PCR does not cut vancomycin duration in ICU CAP
• Expanded TB Screening in HIV Inpatients Shows No Benefit
• FDA Approves Cleocin Hydrochloride (clindamycin) for Serious Infections
• Efavirenz 400 mg Shows Noninferiority to 600 mg in Treatment-Naïve Chinese Patients
• Baricitinib plus remdesivir recovery benefit similar across BMI in COVID-19
• Home visits and HIV self-testing increase CHTC uptake to 56.2% and 50.0% in pregnant couples
• Short-course ceftriaxone reduces hospital stay and adverse events in children with pneumonia
• Measurable targets in National Action Plans are essential for effective antimicrobial resistance mitigation and accountability
• Exercise training increases circulating s-Klotho levels in adults with CKD and sarcopenia
• Hybrid fractionation and Lattice boost provide pain relief and necrosis in inoperable pleomorphic liposarcoma
• Doxycycline significantly reduces Wolbachia burden in patients with bancroftian filariasis
• Topical capsaicin 8% patches improve pain in HIV neuropathy, meta-analysis finds
• HPV16 constitutes 92.5% of single infections in oropharyngeal squamous cell carcinoma cases
• Group B Streptococcus Prevalence and Antimicrobial Resistance in African Populations
• Short-course IV or oral antibiotics may match longer regimens for pediatric bone and joint infections
• Doxycycline is the best supported alternative to benzathine penicillin for treating infectious syphilis
• Loneliness affects 46.9% of people with HIV, social isolation 25.9%
• Inhaled antibiotics may improve lung function and microbiological eradication in cystic fibrosis and bronchiectasis
• Pseudomonas aeruginosa in Africa shows 54.4% pooled antibiotic resistance, 100% to tetracyclines
• Beta-lactam/beta-lactamase inhibitor therapy reduces all-cause mortality in multidrug-resistant Gram-negative infections
• Adequate treatment for maternal syphilis reduces stillbirth odds by 84% in pregnant women
• Antibiotic residues found in 42.6% of chicken products across Africa, meta-analysis reports
• Oral topoisomerase II inhibitors show no significant difference from ceftriaxone for uncomplicated gonorrhoea
• Evaluating the Efficacy of Behavioral Interventions to Improve Antiretroviral Therapy Adherence
• FDA Approves Oxacillin Injection for Penicillinase-Producing Staphylococcal Infections
• FDA Approves Cefazolin in Dextrose Injection for Multiple Infections and Perioperative Prophylaxis
• Antibiotic exposure disrupts gut microbiota in 58% to 94% of critically ill children
• FDA Approves Tivicay PD (dolutegravir) for Pediatric HIV-1 Infection
• FDA Approves Tivicay (dolutegravir) for HIV-1 Infection in Adults and Pediatric Patients
• Evaluation of Once-Weekly Islatravir and Lenacapavir for Chronic HIV-1 Management
• Social media and prior study contacts yield higher retention than partner-seeking apps for HIV prevention
• Health communication strategies for Nigerian parents' vaccine hesitancy identified in systematic review
• Transcriptomic analysis identifies conserved interferon-driven host responses during early and late stages of Leishmaniasis infection
• Defensins serve as versatile scaffolds for antimicrobial-resistant pathogens but are not inherently resistance-proof
• Candidiasis prevalence of 13.46% and Cryptococcal meningitis of 3.15% among HIV-positive individuals
• Traditional Chinese Medicine may reprogram tumor-associated macrophages to overcome chemotherapy resistance in gastric cancer
• Quorum sensing inhibitors offer a promising next-generation anti-infective strategy despite nascent clinical translation
• FDA Approves Baraclude (entecavir) for Chronic Hepatitis B Infection
• FDA Approves Baraclude (entecavir) for Chronic Hepatitis B Infection
• FDA Approves Vancomycin Injection for Septicemia, Endocarditis, and Other Infections
• Mobilome dynamics and mobile genetic elements drive antimicrobial resistance across animal and environmental systems
• Porphyromonas gingivalis PPAD links oral infection to systemic disease via citrullination
• Digital twin technology offers potential for precision dosing and antimicrobial stewardship in complex pharmacotherapy
• Low antimicrobial resistance in Lawsonella clevelandensis infections suggests susceptibility to penicillins, carbapenems, clindamycin, and metronidazole
• Seven genome-wide significant loci and eight HLA alleles associated with shingles susceptibility identified
• Chlamydia trachomatis infection prevalence varies significantly across Canadian populations and anatomical sites
• Neonatal neutrophil function varies by assay; chemotaxis and NETs often constrained
• Berberine trial protocol aims to assess 2-year DFS in stage IIIB, IIIC colorectal cancer
• Tuberculosis prevalence among children with severe acute malnutrition is 13% (95% CI: 11-16%)
• TCM addition to hemodialysis increases overall response rate in uremia by RR 1.460
• Resistance exercise is the most effective physical activity for improving self-esteem in children and adolescents
• Doxycycline postexposure prophylaxis associated with increased antimicrobial resistance markers in Neisseria gonorrhoeae infections
• Papilloguard with AS04 shows non-inferior immunogenicity to Gardasil in HPV vaccine trial
• WGS-based tools provide high specificity and sensitivity for rifampicin, isoniazid, and fluoroquinolone resistance detection
• Keverprazan-amoxicillin dual therapy shows non-inferior H. pylori eradication versus esomeprazole-amoxicillin
• Decision support tools lower inappropriate antibiotic use in UK adults
• Autoantibodies neutralizing type I IFNs found in 7.9% of COVID-19 patients, strongly linked to severity
• Lariocidin serves as a structurally novel ribosome-targeting lasso peptide against multidrug-resistant pathogens
• TB-TST mobile application increases treatment success to 82% in drug susceptible tuberculosis
• Evaluating Oral Vancomycin Prophylaxis for Clostridium Difficile Infection in Hematopoietic Stem Cell Transplant Patients
• Impact of Systemic Prophylactic Antibacterials on Ventilator Associated Pneumonia in ICU Patients
• Modified regimens for drug-resistant tuberculosis show higher success rates than standard regimens in Cameroon
• Dapsone 5% and erythromycin 2% significantly reduce inflammatory lesion counts in acne vulgaris
• Intrawound antibiotic powder reduces fracture-related infection odds by 37% in pelvic and lower-limb fractures
• NRF2 signaling promotes tumor cell survival and multidrug resistance in advanced hepatocellular carcinoma
• MRSA prevalence in Indonesia is 41%, rising to 59% in recent years
• Cytomegalovirus and Long COVID represent convergent failures of host-virus resilience networks and inflammatory circuits
• Heterophils lack MPO but share conserved granulopoiesis programs with neutrophils
• Baseline auramine count predicts tuberculosis failure or relapse by 5% higher odds per 100 bacilli
• Tailored TIPS intervention increases anticipated HIV stigma in a church-based community sample
• Faith-based intervention for HIV risk reduction shows significant mediation by self-efficacy in adolescents
• Absolute risk framing increases interest in PrEP by 13.8% compared to relative terms
• Tegoprazan-amoxicillin dual therapy matches quadruple efficacy with fewer adverse events
• Impact of Water Access Vaccination Coverage and Maternal Education on HIV Mortality
• Narratives do not increase perceived susceptibility to antibiotic resistance compared to non-narrative information
• Rifapentine 15 mg/kg and 20 mg/kg yield higher culture conversion than standard 6-month regimen
• Bictegravir-lenacapavir maintains viral suppression with 0.3% difference compared to bictegravir-emtricitabine-tenofovir alafenamide
• Mycophenolate mofetil combined with conventional therapy offers best balance of efficacy and safety
• Treponema phagedenis may contribute to chronic inflammation and lesion recurrence in bovine digital dermatitis
• Evaluating Elective Colectomy for Reducing Diverticulitis Recurrence in Hinchey Ib and II Patients
• HIV co-infection triples MDR-TB mortality risk; low BMI and anaemia also raise risk
• Intraosseous vancomycin reduces primary TKA infection risk and improves local tissue concentrations
• Ceftolozane-tazobactam shows comparable efficacy to ceftazidime-avibactam but lower risk of recurrent infection
• PrEP users show suboptimal vaccination coverage, lowest for HPV at 43%
• C-reactive protein testing impacts antibiotic prescribing rates in acute COPD exacerbations
• FDA Approves Veklury (remdesivir) for COVID-19 in Adults and Pediatric Patients
• Skin colonization by Candida auris is a key factor in high transmissibility and outbreak potential
• Hydrogen sulfide mediates bacterial antibiotic tolerance through iron chelation, efflux pump activation, and metabolic dormancy
• FDA Approves Dyna-hex 4 (chlorhexidine gluconate) for Healthcare Personnel Handwash
• FDA Approves Kaletra (lopinavir/ritonavir) for HIV-1 Infection in Adults and Children
• FDA Approves Kaletra (lopinavir/ritonavir) for HIV-1 Infection in Patients 14 Days and Older
• FDA Approves Dyna-hex 2 (chlorhexidine gluconate) for Surgical Hand Scrub and Healthcare Personnel Handwash
• Digital PCR provides a strong correlation with plaque assays for disinfectant efficacy testing
• Protocol for comparing azithromycin and doxycycline with beta-lactams in community-acquired pneumonia
• Bacteriophages show promise as targeted anti-caries agents in systematic review
• PPI deprescription associated with 3.66 odds of CDI in hospitalized older adults
• Antimicrobial resistance drivers in human and agricultural sectors contribute to 4.95 million annual deaths
• Intravesical aminoglycoside instillations reduce recurrent urinary tract infection risk with an IRR of 0.23
• Comparing antimicrobial resistance to COVID-19 does not reduce antibiotic seeking intentions in US adults
• Voriconazole and surgical management successfully treated Aspergillus flavus infection in a patient with spondylolisthesis
• Ensitrelvir plus standard of care does not improve clinical recovery in hospitalized COVID-19 patients
• 4CMenB vaccine did not reduce infection rates compared to placebo in MSM population
• FDA Approves Augmentin XR (amoxicillin/clavulanate) for Community-Acquired Pneumonia and Acute Bacterial Sinusitis
• FDA Approves Augmentin (amoxicillin/clavulanate) for Bacterial Infections
• FDA Approves Augmentin (amoxicillin/clavulanate) for Bacterial Infections
• Chinese pediatric surgeons know prophylaxis guidelines but often fail to stop antibiotics at 24 hours
• Genome-predicted PBP profiling shows high agreement with phenotypic testing for pneumococcal beta-lactam susceptibility
• Nocardia keratitis virulence factors and host immune pathways mapped in systematic review
• HIV-related factors including antiretroviral therapy and low CD4+ counts associate with higher cardiovascular risk
• SP+AQ cuts malaria incidence 54.6% versus SP alone in African children
• Tablet-guided training improves HIV index case testing fidelity by 30.5 percentage points
• Bidirectional automated texting engages 60.3% of people living with HIV for cardiovascular health
• Dual-ART and triple-ART both reduce plasma biomarkers of immune activation and neuronal injury
• Dolutegravir and lamivudine achieved 78% HIV-1 RNA suppression in patients with isolated reactive anti-HBc
• Impact of Rapid Multiplex Point of Care Testing on Antibiotic Prescribing
• Fidaxomicin and vancomycin pulse and taper regimens show potential for reducing Clostridioides difficile recurrence
• Magnesium phosphate cements demonstrate superior biological interactions and faster resorption than calcium phosphate cements
• Targeted interventions increase condom use and HIV knowledge among long-distance truck drivers
• Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon
• Chlorhexidine reduces alveolar osteitis risk by 42.9% after third molar surgery
• Sotorasib resistance linked to transformation to pulmonary giant cell carcinoma in KRAS G12C lung adenocarcinoma
• Antimicrobial additives in resin-based endodontic sealers enhance antibacterial activity against Enterococcus faecalis
• Multimodal laboratory diagnostics improve detection of biofilm-encased pathogens and polymicrobial infections in bone and joint infections
• TCM-based extracts reduce pain in oral lichen planus by 0.86 points on VAS
• Image-guided RFA and MWA show comparable efficacy and safety for small to medium hepatocellular carcinoma
• NLRP3 inhibition and IL-1 receptor blockade attenuate musculoskeletal pathology in alphavirus infections
• Syphilis prevalence is 5.20-fold higher in low-income countries among forcibly displaced populations
• NSP antibody detection aids DIVA interpretation in foot-and-mouth disease but has key limits
• Brain-Lung-Immune-Microbiome Axis replaces biomechanical models in understanding ventilator-associated pneumonia after traumatic brain injury
• FDA Approves Zithromax (azithromycin) for Mild to Moderate Bacterial Infections
• FDA Approves Zithromax (azithromycin) for Mild to Moderate Bacterial Infections
• FDA Approves Zithromax (azithromycin) for Multiple Bacterial Infections
• FDA Approves Zithromax (azithromycin) for Community-Acquired Pneumonia and Pelvic Inflammatory Disease
• FDA Approves Sporanox (itraconazole) for Blastomycosis, Histoplasmosis, Aspergillosis, and Onychomycosis
• FDA Approves Fetroja (cefiderocol) for Complicated UTIs and Hospital-Acquired Pneumonia
• 5-day oral antibiotics as effective as 10-day course for pediatric GAS pharyngitis
• Cefdinir and cefprozil show superior eradication rates compared to penicillin V for Group A streptococcal pharyngitis
• Vonoprazan-amoxicillin dual therapy is a safe alternative to bismuth-containing quadruple therapy for H. pylori
• Favipiravir co-administration with lopinavir-ritonavir increased favipiravir clearance by twofold in COVID-19 patients
• Evaluating Enhanced Intervention Strategies for Trachoma Elimination in Rural Ethiopian Communities
• Health insurance navigation after HIV testing was acceptable for 50.0% of eligible men
• Novel biomarkers and machine learning algorithms facilitate earlier identification and diagnosis of sepsis
• Three-variable stratification tool identifies risk of invasive pulmonary aspergillosis in SFTS patients
• 0.01% atropine reduces axial length by 0.04 mm/year in children with myopia
• Salmonella prevalence in bovine deep tissue lymph nodes reaches 10.8% across 33 studies
• NF-kB pathway serves as a unifying hub for molecular and clinical phenotypes in post-acute infection syndrome
• APOE ε4 status does not significantly impact neurocognitive performance in adults with HIV infection
• Triple antibiotic paste and calcium hydroxide show comparable success in necrotic immature teeth
• Doxycycline provides higher odds of microbiological cure compared to azithromycin in cis-men with chlamydia
• Antibiotic resistance mutations drive H. pylori treatment failure across Asia-Pacific region
• Colistin-based inhalation regimens rank highest for clinical response in multidrug-resistant Acinetobacter baumannii pneumonia
• Many healthcare students lack knowledge that antibiotics do not speed recovery from colds and flu
• Pooled Salmonella prevalence in Ethiopia is 6.7% with significant regional and source variations
• Long-acting injectable antiretroviral therapy shows equivalence to oral therapy in meta-analysis of 9 RCTs
• Cefmetazole or flomoxef linked to higher 14-day mortality vs carbapenems in ESBL-PE bacteremia
• Non-invasive biomarkers offer potential alternatives to invasive kidney biopsy for monitoring renal allograft pathology
• FDA Approves Bicillin C-R (penicillin G benzathine and procaine) for Streptococcal and Pneumococcal Infections
• FDA Approves Bicillin L-A (penicillin G benzathine) for Streptococcal Infections and Syphilis
• FDA Approves Arikayce (amikacin liposome inhalation suspension) for Refractory MAC Lung Disease
• FDA Approves Zevtera (ceftobiprole) for Staphylococcus aureus Bloodstream Infections, ABSSSI, and CABP
• Intralesional human papillomavirus vaccination significantly increases complete clearance of persistent cutaneous warts
• Ensitrelvir improves viral clearance and reduces viral RNA in patients with mild-to-moderate COVID-19
• HBeAg seroclearance in HBeAg-positive chronic hepatitis B correlates with disease remission and reduced hepatocellular carcinoma risk
• Klebsiella pneumoniae shows 44% pooled prevalence of antibiotic resistance in Burkina Faso healthcare settings
• 6-month bedaquiline, linezolid, delamanid, and levofloxacin or clofazimine regimen is noninferior to 9-month standard care
• Berberine reduces weight, lipids in schizophrenia with metabolic syndrome: meta-analysis
• Doravirine and islatravir combination shows reduced virological failure risk in adults with HIV-1
• Climate change drives increased frequency of vector-borne diseases through expansion of endemic areas
• Sugar acts as a pivotal ecological factor influencing metabolism, biofilm formation, and interspecies interactions in dental caries
• Computational strategies facilitate identification of conserved antigens and potential therapeutics in parasitic diseases