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Oncology

1416 published articles · Updated continuously

This week's Oncology digest · 2026-W24
This Week in Oncology: Muscle Loss, HCC Treatment, Breast Radiotherapy
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HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
PFS and ORR fall short as OS surrogates in metastatic RCC
Oncology Meta-analysis
PFS and ORR fall short as OS surrogates in metastatic RCC Analysis shows limitations in using certain metrics to predict cancer survival
In metastatic RCC, PFS and ORR show only moderate correlation with OS, with surrogate thresholds that are not statistically significant.
A large analysis of kidney cancer cases suggests that common clinical markers may not reliably predict how long a patient will live.
PD-1/PD-L1 inhibitors with anti-angiogenic drugs achieve 48% ORR in recurrent or metastatic nasopharyngeal carcinoma
Oncology Meta-analysis
PD-1/PD-L1 inhibitors with anti-angiogenic drugs achieve 48% ORR in recurrent or metastatic nasopharyngeal carcinoma New drug combinations show promise for advanced nasopharyngeal cancer
This meta-analysis of 10 independent cohorts from 9 studies evaluates PD-1/PD-L1 inhibitors combined with small-molecule anti-angiogenic dru…
Combining certain immunotherapy drugs with anti-angiogenic agents shows a 48% response rate for patients with advanced nasopharyngeal cancer…
FOLFOXIRI plus cetuximab does not improve survival or response rates compared to bevacizumab in mCRC
Oncology Meta-analysis
FOLFOXIRI plus cetuximab does not improve survival or response rates compared to bevacizumab in mCRC Trial Shows No Difference Between Two Colorectal Cancer Treatments
This meta-analysis of 561 patients with metastatic colorectal cancer found no significant differences in overall survival, progression-free …
A review of 561 patients found no difference in survival or response rates between two common drug combinations for metastatic colorectal ca…
Home-based exercise rehabilitation may improve cardiorespiratory fitness and quality of life in cancer
Oncology Meta-analysis
Home-based exercise rehabilitation may improve cardiorespiratory fitness and quality of life in cancer Home exercise programs may improve fitness for people with cancer
This meta-analysis of 632 adults with cancer found that home-based exercise rehabilitation incorporating cardiac rehabilitation principles w…
Home-based exercise programs using heart health principles can improve fitness and quality of life for adults living with cancer.
MOL-led WeChat and face-to-face intervention targets 30-day treatment in upper GI cancer
Oncology RCT
MOL-led WeChat and face-to-face intervention targets 30-day treatment in upper GI cancer New Management Plan Aims to Speed Up Cancer Treatment
This cluster randomised controlled trial protocol will test whether a MOL-led management intervention using WeChat-based health education an…
A new trial plans to use WeChat and face-to-face talks to help patients with upper gastrointestinal cancer start treatment faster.
Fine-needle aspiration outperforms exfoliative cytology in pulmonary salivary gland-type tumors
Oncology Meta-analysis
Fine-needle aspiration outperforms exfoliative cytology in pulmonary salivary gland-type tumors Fine needle aspiration shows better accuracy for lung tumor diagnosis
This meta-analysis of 106 patients with primary pulmonary salivary gland-type tumors found cytohistologic concordance of 48.1%. Fine-needle …
Doctors are finding that fine needle aspiration provides more accurate results than other methods for identifying specific types of lung tum…
Circulating tumor DNA correlates with increased risk of aggressive disease progression and reduced overall survival
Oncology Meta-analysis
Circulating tumor DNA correlates with increased risk of aggressive disease progression and reduced overall survival Circulating tumor DNA levels predict survival in multiple myeloma patients
This meta-analysis of 948 patients with multiple myeloma indicates that circulating tumor DNA (ctDNA) is associated with a higher risk of ag…
Detecting specific DNA fragments from tumors can help doctors identify patients with multiple myeloma who may face a more aggressive disease…
Brexucabtagene autoleucel achieves 88% overall response rate in relapsed or refractory mantle cell lymphoma
Oncology Meta-analysis
Brexucabtagene autoleucel achieves 88% overall response rate in relapsed or refractory mantle cell lymphoma Trial Shows Brexucabtagene Autoleucel Provides Durable Benefit for Blood Cancers
This meta-analysis of 31 cohorts evaluates brexucabtagene autoleucel for relapsed or refractory mantle cell lymphoma and B-cell acute lympho…
Brexucabtagene autoleucel shows high response rates and durable benefits for adults with specific types of relapsed or refractory blood canc…
Lower phase angle values correlate with poorer clinical outcomes in patients with colorectal cancer
Oncology Meta-analysis
Lower phase angle values correlate with poorer clinical outcomes in patients with colorectal cancer Lower Phase Angle Linked to Poorer Outcomes in Colorectal Cancer
This systematic review of observational studies indicates that lower phase angle (PhA) values are consistently associated with adverse clini…
Lower phase angle measurements may signal poorer nutritional status and higher risks of complications for patients with colorectal cancer.
Systemic barriers like delayed diagnosis and limited surgery impact survival in high-grade gliomas
Oncology Meta-analysis
Systemic barriers like delayed diagnosis and limited surgery impact survival in high-grade gliomas Systemic Barriers Impact Survival for Patients with High-Grade Gliomas
This meta-analysis of 30 independent studies evaluates survival outcomes for high-grade gliomas in low- and middle-income countries. Finding…
Limited access to surgery, chemotherapy, and early diagnosis creates significant hurdles for patients with high-grade gliomas in developing …
Molecular testing reduces surgical resection rates for indeterminate thyroid nodules in Western and Asian cohorts
Oncology Meta-analysis
Molecular testing reduces surgical resection rates for indeterminate thyroid nodules in Western and Asian cohorts Molecular testing helps decide if surgery is needed for thyroid nodules
This meta-analysis of 127 studies evaluated the impact of molecular testing on surgical management and risk of malignancy for indeterminate …
Molecular testing can help doctors decide if surgery is necessary for thyroid nodules, showing different clinical roles in Western and Asian…
Metal stents provide longer time to recurrent biliary obstruction than plastic stents in malignant biliary obstruction
Oncology Meta-analysis
Metal stents provide longer time to recurrent biliary obstruction than plastic stents in malignant biliary obstruction Metal stents may last longer for blocked bile ducts
This meta-analysis of six studies evaluated EUS-HGS with metal versus plastic stents for malignant biliary obstruction. Metal stents were as…
Metal stents can keep bile ducts open longer than plastic ones, but they may also carry a higher risk of complications.

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