Oncology

All Oncology Articles

• CD30-directed therapy, JAK/STAT inhibition, and checkpoint blockade offer potential options for ALK-negative anaplastic large cell lymphoma
• Early postoperative chemotherapy reduces risk of death in patients with colorectal cancer
• ICI Safety in Early Breast Cancer: Meta-Analysis of 3977 Patients
• Total neoadjuvant therapy improves disease-free survival and doubles pCR in rectal cancer
• Digital behavioral weight loss interventions significantly reduce BMI and waist circumference in breast cancer survivors
• PFOA exposure linked to modest kidney and breast cancer risk in meta-analysis
• Underwater ESD achieves 99% en bloc resection for duodenal tumors, meta-analysis finds
• RGS gene panel achieves 0.98 AUC for breast cancer diagnosis and risk stratification
• Evaluating Exercise Modalities to Improve Sleep Quality in Breast Cancer Survivors
• Ranibizumab and bevacizumab show comparable short-term efficacy for macular edema in retinal vein occlusion
• Computer-aided detection shows high sensitivity and specificity for detecting colorectal polyps of all sizes
• CD73-adenosine axis serves as a metabolic immune checkpoint and potential target to overcome melanoma resistance
• Biochemical marker decline may not indicate clinical stability in intracranial growing teratoma syndrome
• Clinical breast examination uptake in sub-Saharan Africa is low at 13% across pooled data
• Talazoparib plus enzalutamide improves progression-free survival in metastatic prostate cancer with HR gene alterations
• Ivonescimab plus chemotherapy improves overall survival in patients with EGFR-variant nonsquamous NSCLC
• Spatial patterns of glioblastoma progression following upfront chemoradiation and salvage therapy
• AI-driven chatbot prototype shows feasibility in providing MAT standards information to healthcare professionals
• Ganglioneuroblastoma presents as a malignant adrenal tumor with metastatic potential in adult patients
• Concurrent osteosarcoma can be masked by brown tumors in patients with primary hyperparathyroidism
• Contrast-enhanced mammography increases cancer detection by 9.3 per 1,000 compared to low-energy mammography
• No established correlation exists between paragangliomas and cervical lymph node metastasis in papillary thyroid carcinoma
• Local therapy and intrathecal chemotherapy may manage CNS progression in EGFR-mutant NSCLC patients
• Preoperative inflammatory biomarkers SIRI and NLR associate with worse survival in UTUC after RNU
• Mindfulness-based stress reduction significantly reduces anxiety, depression, and fatigue in breast cancer patients
• Sinonasal NUT carcinoma with leptomeningeal carcinomatosis may require early multimodal treatment and surgical intervention
• Metabolic reprogramming and plasticity drive tumor progression and resistance through interconnected transcription factors and enzymes
• Lenvatinib plus pembrolizumab did not improve overall survival compared to standard of care
• Alectinib improves progression-free survival over crizotinib in ALK-positive NSCLC (HR 0.41)
• Daraxonrasib improves overall survival to 13.2 months in mPDAC patients compared to 6.7 months
• DNA Methylation Tests Show High Accuracy for Cervical Cancer Triage
• Minimally invasive pancreaticoduodenectomy reduces blood loss and hospital stay in distal cholangiocarcinoma surgery
• LAMS and BFMS show higher clinical success rates than DPPS for pancreatic fluid collections
• Circulating microRNAs and lipidomic/metabolomic biomarkers show 0.92 SROC AUC for early breast cancer detection
• 5-ALA fluorescence-guided surgery improves gross total resection rates in patients with glioblastoma
• Guselkumab, Secukinumab, and Brodalumab rank highly for PASI 75 and PASI 90 in plaque psoriasis
• Recurrent intracranial dermoid cysts may cause delayed hydrocephalus following spontaneous rupture and ventricular dissemination
• Adenomatoid tumor should be considered in the differential diagnosis for testicular lesions in patients with cryptorchidism
• CAR T-cell therapies targeting specific antigens show potential for treating pediatric CNS tumors
• SDHD Variant Carriers Face High Penetrance and Multifocal Tumors
• Transsphenoidal surgery achieves 73.88% remission rate in Cushing's Disease
• Successful radiation oncology AI integration requires trustworthy ecosystems and human-centered workflow design
• Endoscopic resection followed by esophagectomy shows favorable recurrence-free and disease-specific survival in superficial esophageal cancer
• Comparative Efficacy of Immunotherapy Combinations in Advanced Renal Cell Carcinoma Management
• Bibliometric Analysis Maps Paraptosis Research Landscape in Cancer
• Oral propranolol remains the primary systemic treatment for infantile hemangioma with no superior alternatives
• Soluble CD146 serves as a marker of microvascular stress and promotes tumor invasion
• CXCL16/CXCR6 axis exerts bidirectional regulatory influence on neoplasms and inflammatory disorders like asthma
• Evidence-based guidelines support team-based perioperative glycemic management for patients with hepatocellular carcinoma
• Immune checkpoint inhibitors plus chemotherapy improve overall survival in advanced triple-negative breast cancer
• HPV shows strong association with oropharyngeal SCC while other oncogenic viruses show limited evidence
• FDA Approves Ogsiveo (nirogacestat) for Progressing Desmoid Tumors
• Internal mammary and medial-supraclavicular irradiation reduces breast cancer mortality without improving overall survival
• DEB-BACE Shows Higher Short-Term Response in Unresectable Lung Cancer
• Robotic-assisted thoracoscopic segmentectomy increases lymph node stations examined and reduces hospital stay duration
• Comparative Analysis of Robot Assisted and Laparoscopic Partial Nephrectomy for Renal Tumors
• Retroperitoneal approach in single-port robot-assisted partial nephrectomy may reduce blood loss and hospital stay
• First-line immune checkpoint inhibitor therapy improves progression-free survival and overall survival in MSI-H/dMMR mCRC
• Forty-seven clinically relevant late-phase programs identify development trajectories for PD-1 and PD-L1 therapies through 2030
• Multimodal fusion and radiogenomic frameworks show promise for capturing heterogeneity in triple-negative breast cancer
• Paclitaxel arm achieves 56.4% pathologic complete response compared to 23.7% with endocrine therapy
• Multifaceted preventive nursing program reduces fall incidence from 19.8% to 7.1% in elderly NHL patients
• 5-ALA PDT improves overall response and HPV clearance in cervical squamous intraepithelial lesions
• FDA Approves Retevmo (selpercatinib) for RET-Driven Cancers
• FDA Approves Retevmo (selpercatinib) for RET Fusion-Positive Solid Tumors
• BIRC3::MALT1 fusion detected in 35% of cells in pulmonary MALT lymphoma case
• Indefinite-duration lenalidomide maintenance shows no significant difference in overall survival compared to fixed-duration
• AI plus celecoxib more than doubles odds of clinical response in ER-positive breast cancer
• Endoscopic transsphenoidal surgery increases gross total resection rates for pituitary tumors compared to microscopic techniques
• Problem-focused coping is moderately to strongly associated with benefit finding in adult cancer patients
• Metabolic reprogramming of chondrocytes through impaired oxidative phosphorylation contributes to articular cartilage collapse
• Artificial intelligence improves diagnostic accuracy and treatment planning in prostate cancer management
• AI diagnostic tools show high accuracy but limited real-world validation in systematic review
• Surgical treatment and multimodal therapies characterize management options for rare penile melanoma cases
• HR-positive HER2-low breast cancer accounts for 60% of cases; deruxtecan reshapes treatment
• Parasite-derived molecules exert both pro-tumour and anti-tumour effects in experimental cancer models
• Olanzapine containing regimens consistently improve complete response across all phases of chemotherapy-induced nausea and vomiting
• Intimate partner violence triples cervical cancer risk in meta-analysis of adult women
• Platelet-rich fibrin may reduce medication-related osteonecrosis of the jaw risk during tooth extractions
• Very late-onset Myasthenia Gravis is associated with higher AChR-antibody positivity and lower thymoma prevalence
• PSMA-targeted radioligand therapies including 177Lu-PSMA-617 improve progression-free survival and overall survival in mCRPC
• PD-1 inhibitor plus chemotherapy improves progression-free survival and overall survival in driver gene-negative NSCLC
• TROP2-targeting ADCs achieve 50.6% ORR in EGFR-mutant NSCLC following tyrosine kinase inhibitor failure
• Doxorubicin-loaded graphene nanoplatform chemo-photothermal therapy significantly suppresses tumor volume in breast cancer xenograft models
• EUS-guided transmural bypass achieves 93.5% technical success in patients with afferent loop syndrome
• Metabolic reprogramming of myeloid cells shapes spatial niches and immunometabolic landscapes in brain tumors
• High red meat consumption increases pancreatic cancer risk by 16% in large population meta-analysis
• Neoadjuvant chemotherapy with angiogenesis inhibitors increases pathological complete response rates in triple-negative breast cancer
• FDA Approves Verzenio (abemaciclib) for Early and Advanced Breast Cancer
• FDA Approves Gleevec (imatinib) for Multiple Kinase-Driven Cancers
• Tamoxifen reduces distant recurrence risk by HR 0.37 in PR-positive postmenopausal breast cancer
• Late grade 2 or higher gastrointestinal toxicity is inversely associated with biochemical recurrence in prostate cancer
• Direct-acting antivirals achieve 89% sustained virologic response in patients with hepatocellular carcinoma and HCV
• Prophylactic PEG tube placement improves nutritional status and reduces hospitalizations for head and neck cancer patients
• FDA Approves Padcev (enfortumab vedotin) for Muscle Invasive Bladder Cancer
• Gut microbiome taxa and metabolites enhance immune checkpoint inhibitor efficacy and mitigate systemic toxicity
• Post-diagnosis physical activity of 7.5 MET-hr/week associated with lower all-cause mortality in prostate cancer
• Comparative Efficacy of PD-1 and PD-L1 Inhibitors in Advanced Non-Small Cell Lung Cancer
• EUS-HGAS provides longer time to recurrent biliary obstruction than EUS-HGS in malignant biliary obstruction
• Axicabtagene ciloleucel shows higher early response but greater toxicity than tisagenlecleucel in large B-cell lymphoma
• Transcriptome-wide meta-analysis identifies over 1,095 differentially expressed genes in vestibular schwannoma
• Neoadjuvant gemcitabine plus nab-paclitaxel vs gemcitabine plus S-1 for geriatric pancreatic cancer
• Hangeshashinto may reduce oral mucositis risk in chemotherapy patients (RR 0.86)
• Omics-guided surgical paradigms may identify specific patients for selective retroperitoneal clearance in advanced ovarian cancer
• 0.018-inch and 0.022-inch bracket slots show no clinically relevant differences in orthodontic outcomes
• Eosinophils as dual pro-inflammatory and immunoregulatory cells in allergic rhinitis
• Intravesical gemcitabine and docetaxel provide effective treatment for high-risk non-muscle-invasive bladder cancer
• 8-year disease-free survival after surgery alone for clear cell adenocarcinoma of the urethra
• Tumor Treating Fields and pulsed electric fields modulate cell death and immune microenvironment in neoplasms
• Olaparib, rucaparib, and niraparib significantly improve progression-free survival across age groups in advanced ovarian cancer
• Small intestinal metastasis from triple-negative breast cancer can mimic lymphoma on imaging
• High tumour-associated neutrophils at the invasive margin are associated with improved overall survival
• One-time EBRT is as effective as multi-fraction treatments for pain management in malignant bone tumors
• Hyperspectral imaging shows strong diagnostic performance for oral cancer detection in scoping review
• Surgical tract dissemination and cerebrospinal fluid spread contribute to ectopic recurrence of adamantinomatous craniopharyngioma
• Histologic-subtype discordance between core needle biopsy and final pathology occurs in malignant breast adenomyoepithelioma
• Chinese herbal decoctions YHHYT, BZT, and FJHQT show varying efficacy for breast cancer treatment outcomes
• MRI-based artificial intelligence models show promise in predicting biochemical recurrence in prostate cancer
• Synergistic Effects of Immune Checkpoint Inhibitors and Radiotherapy in Solid Tumor Management
• Enhanced communication using behavioral economics principles did not significantly increase FIT test completion rates
• Repetitive transcranial magnetic stimulation addresses various mental disorders including depression, bipolar disorder, and schizophrenia
• Endoscopic mucosal resection confirms rare gastric plasmacytoma in 53-year-old man
• Mandala painting and music therapies improve quality of life and psychological well-being in cancer survivors
• Reverse-bevel ProCore FNB provides diagnostic yield comparable to standard FNA for pancreatic mass lesions
• FDA Approves Kisqali (ribociclib) for Adjuvant Treatment of Early Breast Cancer
• FDA Approves Kisqali Femara Co-pack (ribociclib/letrozole) for HR+/HER2- Early and Advanced Breast Cancer
• Neuroendoscopic resection of a collision tumor involving null-cell adenoma and Adamantinomatous craniopharyngioma
• Early recognition of femoral metastasis in HNSCC is essential to facilitate timely palliative intervention
• KYR intervention is non-inferior to conventional genetic counseling in breast cancer risk knowledge
• EGFR inhibitors show reproducible activity and manageable toxicity in locally advanced or metastatic anal squamous cell carcinoma
• SYHX2011 improves objective response rate to 35.8% compared to 25.8% for PAB in breast cancer
• Tai Chi Chih, cognitive behavioral therapy, and massage therapy reduce cancer-related fatigue in breast cancer
• CT-based deep learning models show high accuracy predicting EGFR mutation status in lung adenocarcinoma
• Radiomics-based artificial intelligence models predict VETC presence in patients with hepatocellular carcinoma
• Liquid biopsy technologies utilizing NGS and machine learning improve analytical sensitivity for early cancer detection
• Rural residence and poor knowledge increase odds of delayed health-seeking behavior for cancer patients
• Multicomponent nonpharmacological interventions reduce delirium incidence in adult patients with cancer
• Higher log GDP per capita is associated with higher Comprehensive Score for Financial Toxicity
• Meta Analysis Evaluates Hypokalemia Risks Associated with Androgen Receptor Axis Targeted Therapies
• Neurotoxic chemotherapy causes moderate to large increases in vibration perception threshold in hands and feet
• Serum 25-hydroxyvitamin D shows significant inverse correlation with insulin resistance indices in women with PCOS
• Acupuncture promotes microglial transition from pro-inflammatory glycolysis to anti-inflammatory oxidative phosphorylation metabolism
• Multidimensional models incorporating genomic and microenvironment features likely outperform single-analyte tests to predict immunotherapy response
• miRNA panels show high diagnostic accuracy for endometrial cancer in meta-analysis
• IL-10 rs1800890 variants linked to modestly increased non-Hodgkin lymphoma risk in meta-analysis
• Traditional Chinese medicine may modulate immune resistance barriers in microsatellite-stable colorectal cancer
• Robot-assisted laparoscopic resection provides successful R0 resection for giant pelvic solitary fibrous tumor
• Novel agent-based regimens provide superior efficacy and lower toxicity than traditional chemotherapy in older adults
• CAR-T cell therapy improves progression-free survival (HR 0.55) and overall survival (HR 0.68) in R/R DLBCL
• Robot-assisted radical nephrectomy reduces conversion rates and blood loss compared to laparoscopic surgery for complex tumors
• ALK tyrosine kinase inhibitors achieve 58.5% objective response rate in ALK-positive non-small cell lung cancer
• Paclitaxel monotherapy shows modest activity in relapsed small cell lung cancer
• Preoperative chemoradiotherapy increases R0 resection and pathologic complete response rates in esophageal carcinoma
• Higher serum vitamin D levels linked to small increase in prostate cancer risk
• Second-line immunotherapy combination with etoposide and capecitabine improves extracranial disease control in pulmonary choriocarcinoma
• A 13-year-old female presented with an invasive encapsulated follicular variant of papillary thyroid carcinoma
• Immunohistochemical markers facilitate diagnosis of primary mucinous adenocarcinoma of the bladder in rare cases
• Dexmethylphenidate significantly improves cancer-related fatigue compared to placebo with moderate evidence certainty
• Acupuncture reduces Pittsburgh Sleep Quality Index scores in patients with breast cancer-related insomnia
• FDA Approves Romvimza (vimseltinib) for Symptomatic Tenosynovial Giant Cell Tumor
• FDA Approves Sarclisa (isatuximab) for Multiple Myeloma in Three Combinations
• FDA Approves Trelstar (triptorelin) for Advanced Prostate Cancer
• FDA Approves Trelstar (triptorelin pamoate) for Advanced Prostate Cancer
• FDA Approves Trelstar (triptorelin pamoate) for Advanced Prostate Cancer
• Catheterisation Linked to Small PSA Rise in Men
• Multidisciplinary management of mixed adenoneuroendocrine carcinoma of the gallbladder involves surgery and adjuvant chemotherapy
• Multimodal strategies including bevacizumab and advanced radiotherapy techniques manage radiation-induced brain necrosis
• FDA Approves Orserdu (elacestrant) for ESR1-Mutated Advanced Breast Cancer
• 5-alpha-reductase inhibitors are associated with increased sexual adverse events in androgenetic alopecia patients
• Pretreatment CPS and HPV status correlate with pathological response in neoadjuvant immunotherapy for LAHNSCC
• Non-pharmacological interventions may improve sleep quality, quality of life, and anxiety in lung cancer patients
• Acupuncture Efficacy in Managing Cancer Related Fatigue and Quality of Life
• Multiple clinical and perioperative factors are significantly associated with postoperative abdominal infection in colorectal cancer patients
• Sacituzumab Tirumotecan Combined With Pembrolizumab Improves Outcomes in PD-L1 Positive NSCLC
• Perampanel provides seizure freedom for 42% of patients with brain tumor-related epilepsy
• Meta-analysis Evaluating Occupational Hexavalent Chromium Exposure and Specific Malignancy Risks
• Regenerative medicine strategies show feasibility for dentin-pulp complex regeneration in dental pulp disease
• Extended resection and intensity-modulated radiotherapy managed a rare primary orbit epithelioid sarcoma
• High PTTG1 expression correlates with poorer survival and advanced disease in various solid tumors
• Walking training improves VO2 peak and reduces fatigue in adult cancer patients
• CRT plus EGFR-TKI improves overall survival while EGFR-TKI plus RT ranks first for progression-free survival
• FDA Approves Ibrance (palbociclib) for PIK3CA-Mutated Breast Cancer
• FDA Approves Ibrance (palbociclib) for HR-Positive, HER2-Negative Advanced Breast Cancer
• FDA Approves Trodelvy (sacituzumab govitecan-hziy) for HR+/HER2- Breast Cancer
• Low baseline TKa associated with longer OS of 38.5 months in endocrine-resistant MBC
• HPV prevalence in breast cancer tissue is 23% with higher risk in specific subtypes
• Asparaginase therapy in acute lymphoblastic leukemia patients correlates with increased thromboembolism risk in specific subgroups
• Zinc supplementation shows potential in reducing severe radiation-induced oral mucositis in head and neck cancer patients
• Hybrid multi-component frameworks and qualitative integration characterize best practices in medical device risk management
• Robotic nipple-sparing mastectomy increases total operative time by 64.01 minutes compared to conventional techniques
• Cadmium exposure increases pancreatic cancer risk with an RR of 1.69 across meta-analyzed data
• Mendelian Randomization Evaluates IL-6 Inhibition Effects on Hepatocellular and Colorectal Cancer Risk
• Machine learning models provide statistically significant improvements in 5-year survival prediction for gastric cancer patients
• FH-deficient uterine leiomyoma in young women requires IHC screening and lifelong renal surveillance
• Hypopharyngeal well-differentiated liposarcoma can occur in young adults and may recur early after transoral excision
• Prostatic incidental uptake on FDG PET/CT has a 1.7% prevalence with 21.3% malignancy risk
• Migrated pancreaticojejunal stents may act as chronic local irritants potentially linked to metachronous cholangiocarcinoma
• Combination of Local Treatment and Systemic Therapy Improves Outcomes in Patients with Hepatocellular Carcinoma
• CSF IL-10 demonstrates high diagnostic accuracy and strong rule-in utility for CNSL
• Transoral robotic surgery and transoral laser microsurgery show higher 5-year survival than radiotherapy for supraglottic squamous cell carcinoma