Controlled low central venous pressure with nitroglycerin reduces 7-day postoperative AKI by 14.9% absolute risk
Nitroglycerin may lower kidney injury risk after heart surgery
This randomized controlled trial of 505 patients undergoing cardiac surgery found that controlled low central venous pressure (CLCVP) using …
A new trial shows that using nitroglycerin to manage blood pressure during heart surgery can reduce the risk of early kidney damage.
Acetazolamide reduces AMS risk by 31% but females face 4.8-fold higher risk of side effects
Acetazolamide helps prevent mountain sickness but causes more side effects in women
This randomized clinical trial of 303 healthy residents found that acetazolamide 125 mg twice daily reduced AMS incidence by 31% compared to…
Acetazolamide reduces mountain sickness risk, but women in a new study faced much higher rates of moderate to severe side effects.
Short-term exposure to outdoor air pollution is linked to biochemical markers in emergency department patients
Air Pollution Linked to Biomarkers in Emergency Department Patients
This scoping review examines the impact of short-term exposure to PM2.5, PM10, and NO2 on patients presenting to emergency departments. The …
Short-term exposure to outdoor air pollution is linked to specific markers of inflammation and blood clotting in people visiting emergency d…
Skeletal muscle dysfunction impacts exercise capacity and exacerbation risk in patients with COPD
Muscle Health Linked to Better Outcomes for COPD Patients
This narrative review explores the lung-muscle axis in patients with COPD, linking skeletal muscle dysfunction to impaired physical function…
Weak muscles can lead to lower exercise capacity and higher risk of flare-ups for people living with COPD.
Osimertinib plus chemotherapy improves progression-free survival by 18.4 months in TP53 and EGFR-mutated NSCLC
Adding chemotherapy to osimertinib extends survival for specific lung cancer
This Phase 3 randomized clinical trial of 294 treatment-naive, stage IV or recurrent nonsquamous NSCLC patients with concurrent TP53 and EGF…
A new combination of osimertinib and chemotherapy significantly extends the time patients with specific lung cancer mutations live without d…
Targeted strategies like senolytics and PFKFB3 blockers show preclinical efficacy in chronic kidney disease
New research explores how cells drive chronic kidney disease
This narrative review explores the mechanisms of necroptotic tubular epithelial cell death and glycolytic reprogramming in chronic kidney di…
Scientists identified a self-amplifying cycle of cell death and aging that drives scarring in chronic kidney disease.
Robotic-assisted thoracoscopic segmentectomy results in lower intraoperative blood loss compared to video-assisted thoracoscopic segmentectomy
Robotic surgery shows less blood loss for early lung cancer
This meta-analysis of propensity-matched studies included 14,007 patients with early-stage non-small cell lung cancer undergoing segmentecto…
Robotic surgery may reduce blood loss during lung cancer procedures while providing similar survival rates to traditional methods.
Dysphagia affects 38.2% of COPD patients; advanced disease and tooth loss raise risk
More than one-third of COPD patients struggle with swallowing
This meta-analysis of observational studies including 4608 patients with chronic obstructive pulmonary disease found a pooled dysphagia prev…
Nearly 40% of people with COPD experience dysphagia, a condition that makes swallowing difficult and can impact daily nutrition and safety.
ANCA-associated vasculitis doubles lung cancer risk, meta-analysis finds
Lung Cancer Risk Doubles in Patients with ANCA Vasculitis
This meta-analysis of 8004 patients with ANCA-associated vasculitis (AAV) found a 2-fold increased risk of lung cancer (RR 2.08, 95% CI 1.52…
A large meta-analysis finds that people with ANCA-associated vasculitis have about double the risk of lung cancer compared to the general po…
Etoposide plus cisplatin shows higher treatment completion rate of 89.0% vs. 74.1% in HGNEC
Trial Shows Etoposide and Cisplatin for Neuroendocrine Lung Carcinoma
This post hoc analysis of a Phase III trial evaluated 217 patients with high-grade neuroendocrine carcinoma of the lung who underwent comple…
A trial of 217 patients with lung cancer found that higher doses of certain chemotherapy drugs did not lead to better outcomes.
Endobronchial valve treatment triples peri-procedural mortality odds in severe emphysema
Endobronchial Valve Treatment Shows Mixed Results for Emphysema Mortality
This meta-analysis of 819 patients with severe emphysema found that endobronchial valve (EBV) treatment significantly increased peri-procedu…
New analysis of 819 patients shows that while endobronchial valves do not change overall mortality, risks are higher in the first 90 days.
Tailored Physical Activity Programs Improve Functional Capacity and Symptoms in Lung Cancer Patients
Patient-centered physical activity helps manage lung cancer symptoms
Meta-analysis results indicate that personalized exercise programs significantly improve functional capacity and reduce symptoms in lung can…
Tailored exercise programs can improve physical ability and reduce symptoms for people living with lung cancer.
All Pulmonology & Critical Care Articles
- Controlled low central venous pressure with nitroglycerin reduces 7-day postoperative AKI by 14.9% absolute risk
- Acetazolamide reduces AMS risk by 31% but females face 4.8-fold higher risk of side effects
- Short-term exposure to outdoor air pollution is linked to biochemical markers in emergency department patients
- Skeletal muscle dysfunction impacts exercise capacity and exacerbation risk in patients with COPD
- Osimertinib plus chemotherapy improves progression-free survival by 18.4 months in TP53 and EGFR-mutated NSCLC
- Targeted strategies like senolytics and PFKFB3 blockers show preclinical efficacy in chronic kidney disease
- Etoposide plus cisplatin shows higher treatment completion rate of 89.0% vs. 74.1% in HGNEC
- Endobronchial valve treatment triples peri-procedural mortality odds in severe emphysema
- Tailored Physical Activity Programs Improve Functional Capacity and Symptoms in Lung Cancer Patients
- Critically ill lung cancer patients face 73.5% long-term mortality and 51.9% hospital mortality
- Dysphagia affects 38.2% of COPD patients; advanced disease and tooth loss raise risk
- ANCA-associated vasculitis doubles lung cancer risk, meta-analysis finds
- Robotic-assisted thoracoscopic segmentectomy results in lower intraoperative blood loss compared to video-assisted thoracoscopic segmentectomy
- Triple therapy improves SGRQ scores in stable COPD but increases pneumonia risk compared to dual bronchodilation
- iNKT cell activators show promise in preclinical models for stroke-associated pneumonia immunomodulation
- Exercise reduces inflammatory markers in 45.6% of meta-analytic associations, but evidence quality is low
- FDA Approves Jascayd (bexotegrast) for Idiopathic Pulmonary Fibrosis and Progressive Pulmonary Fibrosis
- COPD and OSA overlap syndrome is associated with greater disease burden than either condition alone
- Low-dose corticosteroids reduce 90-day mortality in adults with severe community-acquired pneumonia
- Personalised CT feedback fails to boost quit rates overall in lung cancer screening
- Ultrasound Assessment of Diaphragm Function for Predicting Weaning Success in AECOPD Patients
- EIT-based PEEP titration reduces mortality rate in patients with acute respiratory distress syndrome
- Probiotic regimens may reduce cough duration and illness length in children with respiratory infections
- FDA Approves Orenitram (treprostinil) for Pulmonary Arterial Hypertension
- Occupational exposure to asbestos-free talc does not support increased risk of lung or laryngeal cancers
- Local ablative therapy integrated with first-line EGFR TKI improves progression-free survival and overall survival
- CDQ yields highest sensitivity and AUC for identifying patients with chronic obstructive pulmonary disease
- Reactive nodular fibrous pseudotumor presents with distinct immunohistochemical profiles and no progression in patients
- Respiratory trajectories vary by gestational age in infants born before 26 weeks' gestation
- Non-pharmacologic therapies improve cough in lung cancer; pulmonary rehabilitation may work best
- Immunocompromised Status Associated with Poorer Outcomes in Patients Requiring ECMO for Acute Respiratory Distress Syndrome
- Delirium prevalence of 41% among patients with acute respiratory distress syndrome
- Rapid on-site evaluation achieves 88.1% sensitivity and 91.7% specificity for lung cancer detection
- Evaluating Bevacizumab Addition to Atezolizumab Carboplatin and Pemetrexed in Nonsquamous NSCLC
- Chemoimmunotherapy improves objective response rate and survival in advanced pulmonary large-cell neuroendocrine carcinoma
- Lily polysaccharide may mitigate radiation-induced pneumonitis by modulating the gut-lung axis and pulmonary signaling
- Early assessment at 4 weeks versus 8 weeks increases abstinence odds in tobacco users
- Treatable traits protocol aims to reduce exacerbations in AECOPD patients
- Polygenic risk scores and air pollutants associated with increased lung cancer risk
- Ensartinib improves 24-month disease-free survival to 86.4% in resected ALK-positive NSCLC
- Low-dose N-acetylcysteine reduces acute exacerbation risk in patients with chronic obstructive pulmonary disease
- Health literacy-sensitive self-management programs improve exercise capacity and symptom burden in patients with COPD
- Biologic therapies targeting T2 inflammatory pathways reduce exacerbation rates in COPD patients
- Organizational resilience and psychological support are key to improving ICU nurse teamwork during pandemics
- Type-2 targeted biologics reduce moderate-to-severe exacerbations in patients with eosinophilic or type 2 COPD
- Individualised PEEP lowers driving pressure but not pulmonary complications in older lung cancer surgery patients
- Aumolertinib Combined with Chemotherapy Improves Progression Free Survival in EGFR Mutated NSCLC
- Nivolumab plus chemotherapy improves pathological complete response in resectable NSCLC with PD-L1 < 1%
- Deep learning AI models for lung nodule malignancy classification show 88% sensitivity and 75% specificity
- Biallelic SLCO2A1 variants may be associated with myelofibrosis in patients with primary hypertrophic osteoarthropathy
- Energy therapies improve exercise capacity and quality of life in patients with chronic obstructive pulmonary disease
- HITHOC with cytoreductive surgery improves survival in pleural mesothelioma without raising early postoperative risk
- WHO reporting system provides balanced diagnostic accuracy for malignancy risk in lung lesions
- Higher Ventilatory Ratio values are associated with increased mortality risk in patients with acute respiratory distress syndrome
- Sublobar resection associated with improved overall survival compared to SBRT in early-stage non-small cell lung cancer
- Osimertinib treatment for EGFR-mutated NSCLC results in hypertension as the most common CVAE
- Inspiratory muscle training improves inspiratory muscle strength and exercise tolerance in stable COPD patients
- Early vvECMO initiation protocol for adult patients with severe ARDS is currently being evaluated
- Metabolic abnormalities are significantly associated with pulmonary infections and asthma exacerbations in children
- Supervised structured exercise improves cardiorespiratory fitness in adults with MASLD by 3.52 mL/kg/min
- COPD caregiver health literacy is low, assessment tools lacking, scoping review finds
- Elevated nocturnal respiratory rate is associated with increased odds of diabetes mellitus in large cohorts
- Vitamin D deficiency increases odds of sepsis and mechanical ventilation in neonates
- FDA Approves Provocholine (methacholine chloride) for Bronchial Airway Hyperreactivity Diagnosis
- Tislelizumab plus chemotherapy improves survival in extensive-stage small cell lung cancer
- Lower PEEP may increase ventilator-free days in ventilated patients without ARDS
- Machine learning models show moderate accuracy predicting neoadjuvant immunotherapy response in NSCLC
- Meta-analysis links baseline and dynamic ctDNA to survival in advanced NSCLC
- COPD patients show heightened sympathetic nerve activity compared to healthy adults
- 1 in 7 COPD patients decline or discontinue long-term PAP therapy, meta-analysis finds
- Pirfenidone reduces lung cancer incidence by 73% in IPF patients with a pooled risk ratio of 0.39
- Immune checkpoint inhibitors before lung cancer surgery show acceptable safety profile
- Irinotecan plus cisplatin shows no RFS benefit over etoposide plus cisplatin in resected lung HGNEC
- Metabolomics profiles show elevated phenylalanine and lactate alongside depleted sphingosine 1-phosphate and citrulline in ARDS patients
- Cutaneous immune-related adverse events associated with improved progression-free survival in non-small cell lung cancer
- Respiratory microbiome composition in children offers new ideas for precision treatment of respiratory diseases and asthma
- Systematic review links specific TCM constitutions to worse COPD outcomes in 2,168 patients
- Subcutaneous astegolimab reduced COPD exacerbations in phase 2b and 3 trials versus placebo
- Case report of 3-year-old girl with bilateral Wilms tumor and TP53 mutation treated with VAD chemotherapy and surgery
- Delayed arousal timing links to higher mortality in sleep apnea patients
- Case report suggests second primary glioblastoma in ALK-positive lung adenocarcinoma patient treated with ensartinib and lorlatinib
- Systematic review and meta-analysis shows individualized EIT-guided PEEP reduces postoperative atelectasis in laparoscopic surgery patients
- FDA Approves Adempas (riociguat) for Chronic Thromboembolic and Pulmonary Arterial Hypertension
- Post hoc reanalysis suggests stereotactic radiotherapy may improve local control in medically inoperable Stage I non-small cell lung cancer
- Meta-analysis finds immunotherapy improves survival in mesothelioma
- Systematic review and meta-analysis of repeat corticosteroids in PPROM shows increased maternal infection risk
- Meta-analysis finds balance training improves balance in COPD patients receiving pulmonary rehabilitation
- Real-world meta-analysis supports pembrolizumab for advanced NSCLC with high PD-L1
- Meta-analysis shows biologic therapies reduce annual exacerbations in COPD patients with high eosinophils while maintaining safety profiles
- FDA Approves Breztri Aerosphere (budesonide/glycopyrrolate/formoterol) for COPD Maintenance
- Review of animal models shows unclear causal links between microbial dysbiosis and pulmonary fibrosis
- RNK08954 shows unconfirmed responses in KRASG12D-mutant NSCLC and PDAC in Phase Ia trial
- Subcutaneous tislelizumab shows comparable trough concentrations to intravenous dosing in treatment-naive advanced non-small cell lung cancer patients
- Evidence-based review of transducer selection for lung ultrasound in dogs and cats with pulmonary pathology
- Toripalimab plus anlotinib maintenance shows promise in ES-SCLC after first-line chemo
- Combination therapy shows promising progression-free survival in advanced non-small cell lung cancer patients with high PD-L1 expression
- Dry NaCl Inhalation Fails to Improve Mucociliary Clearance in COPD
- Pembrolizumab improves overall survival versus chemotherapy in Chinese patients with advanced NSCLC and PD-L1 expression
- Meta-analysis shows platinum-etoposide plus PD-1/PD-L1 inhibitor improves survival in extensive-stage small-cell lung cancer
- Systematic review and meta-analysis shows immune checkpoint inhibitors improve survival in first-line ES-SCLC but not as single agents in second-line
- Network meta-analysis of anti-PD-1/PD-L1 regimens in advanced non-squamous NSCLC without EGFR or ALK alterations
- Lung Ultrasound Shows Good Diagnostic Accuracy for ARDS in Meta-Analysis of 5888 Patients
- Review of CFTR modulator impact on cystic fibrosis outcomes from registry data
- Pulmonary barotrauma incidence and risk factors in non-HIV PCP patients
- LSTM analysis of infant tidal breathing detects bronchopulmonary dysplasia with 97% accuracy
- Review synthesizes pilot data on nasal microbiota and respiratory outcomes in infants
- Smartphone app-based music PR program improves walking distance in COPD patients
- Narrative review discusses tumor draining lymph nodes as a target for NSCLC therapy
- Systematic review and meta-analysis of pharmacist-led care in COPD
- Meta-analysis of 15 observational studies links e-cigarette use to higher COPD odds
- Retrospective Study Shows 3D ResNeXt Classifier Distinguishes NTM-LD from PTB in 409 Patients
- Preclinical pig study tests lung ultrasound for regional strain quantification
- FeNO measurement shows limited diagnostic performance for asthma in school-age children
- CPET reference values established for asymptomatic repaired Tetralogy of Fallot patients
- Lung ultrasound and thoracic radiography for acute respiratory distress in dogs and cats
- Host transcriptional biosignatures for TB progression in Indian household contacts
- Network meta-analysis of acupuncture interventions for acute exacerbation of chronic obstructive pulmonary disease
- Retrospective review of methylprednisolone response in children with TBX4-associated pulmonary hypertension and interstitial lung disease
- Feasibility study abstract evaluates home spirometry and FeNO for asthma diagnosis in adults
- Narrative review examines lung microbiome and mucosal IgA in chronic inflammatory lung diseases
- Review of preclinical EVs for sepsis-associated acute lung injury
- Multicomponent breathing and exercise program improves breathlessness mastery in moderate to severe COPD
- Systematic review and meta-analysis of pulmonary telerehabilitation versus center-based care in COPD
- Systematic review finds high relapse rates in pulmonary sarcoidosis across diverse study designs
- LSTM-based model showed improved ventilator triggering metrics compared to Auto-Trak in a small trial
- Umbilical cord-derived mesenchymal stromal cells for severe COVID-19 ARDS show qualitative improvement and tolerability
- Hospitalized COVID-19 patients receiving antiviral, antiretroviral, or immunosuppressive treatments showed variable outcomes
- SABR shows 46% 5-year overall survival in unfit NSCLC patients in phase 2 trial
- Nine patients with PPFE and DGUOK-associated mitochondriopathy show specific genetic and cellular findings
- Spirometry restriction linked to higher interstitial lung disease and mortality risk in a large cohort
- AI nomogram predicts malignancy risk in surgically resected pulmonary nodules ≤3 cm
- FDA Approves Tyvaso (treprostinil) for Pulmonary Arterial Hypertension and Pulmonary Hypertension Associated with Interstitial Lung Disease
- In a phase 2 trial, [Ga]Ga-SSO120 PET/CT detected malignancies in 18 of 19 patients with small cell or large cell neuroendocrine lung cancer
- Prophylactic rhG-CSF with platinum chemotherapy improves immune markers and response rates in advanced lung cancer patients
- Virtual wards and hospital at home show no survival or readmission benefit for ECOPD patients compared to hospital admission
- Mindfulness interventions show mixed effects on breathlessness and pulmonary function in lung cancer patients
- Phase Ib/II trial of nintedanib plus nivolumab in pretreated NSCLC adenocarcinoma shows 25% 6-month PFS rate
- Non-cirrhotic portal fibrosis identified in 32.6% of pre-cirrhotic primary biliary cholangitis patients in a retrospective analysis
- First-line osimertinib shows high response rates in EGFR-mutated NSCLC with active brain metastases
- EMG measurement is feasible in primary care for stable mild to moderate COPD patients
- Age-period-cohort analysis shows declining bacteriologically confirmed pulmonary tuberculosis incidence in Hunan Province, China, 2009–2023
- Retrospective study links IVIG plus azithromycin to higher response rate in pediatric Mycoplasma pneumoniae pneumonia
- Meta-analysis finds inhaled corticosteroids associated with reduced cardiovascular mortality in COPD patients
- In vitro amikacin resistance linked to kanamycin cross-resistance but not streptomycin in M. avium-intracellulare complex
- Daily Vitamin D increased HDAC2 and 25(OH)D levels in stable COPD patients without improving pulmonary function
- Higher Red Cell Distribution Width to Albumin Ratio (RAR) associated with increased mortality in pulmonary sepsis
- Meta-analysis finds limited evidence for CPET variables in COPD mortality prediction
- Monthly phone counseling increased willingness to set lifestyle goals in patients with chronic obstructive pulmonary disease
- Genetic analysis links oral microbiota to COPD risk in East Asian population
- Low-dose theophylline shows modest FEV improvement but no exacerbation reduction in mild to moderate COPD
- Prolonged prone positioning shows oxygenation benefit but inconclusive mortality effect in COVID-19 ARDS
- FDA Approves Nintedanib Capsules (nintedanib esylate) for Idiopathic Pulmonary Fibrosis and Progressive Fibrosing ILDs
- FDA Approves Nintedanib Capsules (nintedanib esylate) for Idiopathic Pulmonary Fibrosis and Progressive Fibrosing ILDs
- SBRT shows early QoL advantage over CHRT in inoperable stage I NSCLC, but long-term scores converge
- Firmonertinib plus anlotinib shows preliminary efficacy in advanced EGFR-mutant NSCLC
- Retrospective cohort study of 74 patients with Chlamydia psittaci pneumonia identifies prognostic indicators and severity associations
- Systematic review of Traditional Chinese Exercise shows improved function and well-being in 2434 COPD patients
- Nonintubated anesthesia lowers postoperative NLR in thoracoscopic lung cancer resection compared to traditional intubation
- Phase II studies evaluate tislelizumab plus sitravatinib or anlotinib maintenance in extensive-stage small-cell lung cancer
- Extended prone positioning associated with lower mortality but more pressure injuries in COVID-19 ARDS
- BACE plus tislelizumab shows activity in advanced NSCLC patients ineligible for standard care
- Durvalumab plus chemotherapy shows 35% response in phase II trial for metastatic pulmonary sarcomatoid carcinoma
- Meta-analysis compares three lung fiducial marker insertion approaches for stereotactic body radiotherapy
- Non-powered stapler linked to fewer postoperative air leaks than powered stapler in severe emphysema LVRS
- Phase I study finds amrubicin-cisplatin with radiotherapy feasible in limited-stage SCLC
- Sputum quality does not affect Xpert MTB/RIF Ultra accuracy for tuberculosis diagnosis in multi-country study
- Observational report describes hospitalized EVALI cases in the United States
- Updated recommendations issued for tuberculosis prevention, control, and elimination
- Updated clinical guidance issued for suspected e-cigarette or vaping product use-associated lung injury
- Three Cases of Multidrug-Resistant Tuberculosis Identified Among Ohio Food Processing Workers
- Nivolumab with chemotherapy and bevacizumab shows improved 4-year survival in advanced nonsquamous NSCLC
- Residential Ammonia Gas Release Leads to Emergency Visits and Hospitalizations
- Progress toward tuberculosis elimination in the United States has slowed
- U.S. COPD prevalence patterns similar across smoking status groups in 2017 observational data
- 215 possible severe pulmonary disease cases associated with e-cigarette use across 25 states
- Interim guidance issued for evaluating patients with suspected vaping-associated lung injury
- Utah EVALI case series describes patient characteristics and vaping practices
- Report describes changes in tuberculosis incidence across the United States population
- Global report assesses progress toward tuberculosis incidence reduction targets
- US survey finds higher COPD prevalence in nonmetropolitan versus metropolitan areas
- U.S. tuberculosis incidence data reported for 2021 in observational analysis
- Field investigation report describes pneumonic plague case(s) in Wyoming in 2021
- Clinical prediction model differentiates NTM pulmonary disease from tuberculosis in hospitalized patients
- Two lung transplant recipients developed Legionnaires' disease from a single donor
- Observational report examines COPD prevalence in US adults aged 18 years and older
- U.S. TB Incidence Increased in 2022, With Ongoing Racial and Ethnic Disparities
- U.S. workers' idiopathic pulmonary fibrosis mortality described by industry and occupation
- Pilot project describes TB contact management in Ugandan households without reported outcomes
- Tuberculosis Cases Increased in the United States During 2023
- Surveillance report updates tuberculosis elimination progress and program performance in the United States from 2016 to 2022
- CureTB program evaluated continuity of care for tuberculosis patients relocating internationally
- ERAS-guided refined nursing associated with earlier mobilization after lung cancer surgery in retrospective cohort
- Phase 2 trial of high-dose thoracic reirradiation shows 30-month median OS for recurrent lung cancer
- Phase 2 trial finds no significant PFS benefit adding SABR to nivolumab in advanced NSCLC
- Vitamin D3 supplementation improved exercise tolerance in deficient male COPD patients in small RCT
- Perioperative tislelizumab plus chemotherapy improves survival in Chinese patients with resectable NSCLC
- Antenatal dexamethasone reduces respiratory support need in late preterm infants in Vietnamese RCT
- Lung cancer trial patients show disparities in optional biospecimen study participation
- HFNC reduces oxygen desaturation and procedure interruptions during bronchoscopy in high-risk patients
- Amivantamab-lazertinib shows OS benefit over osimertinib in Asian EGFR-mutant NSCLC subset