Gut microbiota-associated metabolites and microbial products influence renal inflammatory and fibrotic responses in diabetic kidney disease
Gut bacteria and metabolites may impact diabetic kidney disease
This narrative review examines the role of gut microbiota-associated metabolites and microbial products in diabetic kidney disease. The auth…
Changes in gut bacteria and the chemicals they produce may play a role in how diabetes affects kidney health.
nsMRA plus SGLT2 inhibitor combination therapy reduces ACR by approximately 33% in CKD patients
Combination therapy shows better kidney protection for chronic disease
This meta-analysis of 1835 adults with CKD and albuminuria found that nsMRA plus SGLT2 inhibitor combination therapy resulted in a greater r…
Combining two specific medications may better reduce protein in the urine for people with chronic kidney disease, though it carries a higher…
Psychosocial interventions significantly reduce depressive symptoms in patients with stage 4 or 5 chronic kidney disease
Psychosocial Interventions Reduce Depression in Chronic Kidney Disease Patients
This meta-analysis of 792 patients with chronic kidney disease found that psychosocial interventions, primarily cognitive-behavioral therapy…
Psychosocial treatments like cognitive-behavioral therapy may help reduce depressive symptoms for patients living with advanced chronic kidn…
Older donor age is associated with higher mortality and graft loss in kidney transplant recipients
Older Donor Age Linked to Lower Survival in Kidney Transplants
This meta-analysis of 7 observational studies involving 19,210 kidney transplant recipients found that older donor age is associated with in…
A large review of kidney transplant data shows that older donor age is linked to higher risks of graft loss and patient mortality.
Higher education reduces cognitive impairment risk while multiple comorbidities and dialysis factors increase cognitive frailty
Factors linked to cognitive decline in patients on hemodialysis
This umbrella review and meta-analysis examines factors associated with cognitive impairment and cognitive frailty in adults receiving hemod…
New data identifies specific risks like stroke history and dialysis duration that may impact brain health for patients on hemodialysis.
Active serum phosphorus reduction reduces all-cause mortality and dialysis risk in non-dialysis CKD patients
Lowering phosphorus levels may help patients with chronic kidney disease
This meta-analysis of randomized controlled trials involving 3149 patients found that actively reducing serum phosphorus significantly reduc…
Lowering phosphorus levels in the blood may reduce the risk of death and delay the need for dialysis for people with chronic kidney disease.
CKD-MBD care should shift from biochemical targets to phenotype-informed, outcome-oriented management
New approach to managing bone and vascular health in kidney disease
This narrative review argues that chronic kidney disease-mineral and bone disorder (CKD-MBD) management should move beyond biochemical targe…
Doctors are pushing for a new way to treat bone and blood vessel issues in patients with chronic kidney disease.
H. pylori eradication linked to lower proteinuria and reduced CKD risk in meta-analysis
Treating a common stomach bacteria may help manage kidney disease
This meta-analysis examines the association between Helicobacter pylori eradication and kidney outcomes in patients with kidney disease or p…
Treating a common stomach infection called H. pylori may lower protein levels in the urine and reduce the risk of chronic kidney disease.
Intermittent Hemodialysis Falls Short of Continuous Therapy in Critically Ill AKI Trial
Trial shows continuous renal-replacement therapy may reduce kidney injury mortality
In critically ill adults with acute kidney injury, intermittent hemodialysis did not prove noninferior to continuous therapy and was linked …
A trial of 554 critically ill adults found that continuous renal-replacement therapy was associated with lower mortality rates than intermit…
Febuxostat lowers serum urate but renal function declines in UMOD-related kidney disease
Febuxostat Treatment Linked to Worsening Kidney Function in Case Study
This case report with literature review describes a 25-year-old man with a UMOD variant and hyperuricemia treated with febuxostat. Serum ura…
A case report shows a patient with a specific kidney disease experienced worsening renal function while taking febuxostat for high uric acid…
Prolonged emergency department boarding is associated with increased aggression and violent incidents in psychiatric patients
Longer wait times in emergency rooms linked to patient aggression
This systematic review of 12 studies examines the impact of emergency department boarding duration on psychiatric patients. The review finds…
Patients with mental health issues are more likely to experience violence or aggression when they have to wait too long in emergency departm…
FDA Approves Velphoro (sucroferric oxyhydroxide) for Serum Phosphorus Control in Dialysis Patients
FDA Approves New Chewable Drug to Lower Phosphorus in Dialysis Patients
The FDA has approved Velphoro, a chewable phosphate binder, for controlling serum phosphorus levels in adults and pediatric patients aged 9 …
The FDA approved Velphoro, a chewable medicine that helps control phosphorus levels in adults and children 9 and older with chronic kidney d…
All Nephrology Articles
- Gut microbiota-associated metabolites and microbial products influence renal inflammatory and fibrotic responses in diabetic kidney disease
- Higher education reduces cognitive impairment risk while multiple comorbidities and dialysis factors increase cognitive frailty
- Psychosocial interventions significantly reduce depressive symptoms in patients with stage 4 or 5 chronic kidney disease
- Active serum phosphorus reduction reduces all-cause mortality and dialysis risk in non-dialysis CKD patients
- nsMRA plus SGLT2 inhibitor combination therapy reduces ACR by approximately 33% in CKD patients
- Older donor age is associated with higher mortality and graft loss in kidney transplant recipients
- CKD-MBD care should shift from biochemical targets to phenotype-informed, outcome-oriented management
- H. pylori eradication linked to lower proteinuria and reduced CKD risk in meta-analysis
- Febuxostat lowers serum urate but renal function declines in UMOD-related kidney disease
- Intermittent Hemodialysis Falls Short of Continuous Therapy in Critically Ill AKI Trial
- Prolonged emergency department boarding is associated with increased aggression and violent incidents in psychiatric patients
- FDA Approves Velphoro (sucroferric oxyhydroxide) for Serum Phosphorus Control in Dialysis Patients
- FDA Approves Sodium Bicarbonate Injection for Metabolic Acidosis and Urinary Alkalization
- HIF-prolyl hydroxylase inhibitors cause modest VEGF increases and reproducible peripheral edema in chronic kidney disease
- Roxadustat-based regimens result in higher mean hemoglobin levels than ESA-based regimens in peritoneal dialysis
- Iron chelation reduces serum ferritin and iron while increasing hemoglobin in chronic kidney disease
- SGLT2 inhibitors attenuate urinary EGF decline and correlate with improved outcomes in chronic kidney disease
- Coagulopathy and hemodialysis significantly increase odds of post-ERCP bleeding in patients with cirrhosis
- Hypoglycemia prediction models show a pooled AUC of 0.846 for patients with diabetic kidney disease
- Selective aldosterone synthase inhibitors reduce systolic blood pressure by 7.9 mmHg in patients with CKD
- FDA Approves Dextrose 5% and Sodium Chloride 0.11% in Plastic Container for Hydration
- DNS-based interventions may reduce low back pain, but heterogeneity is substantial
- Pulmonary hypertension prevalence 37% in maintenance hemodialysis patients, meta-analysis finds
- URS and RIRS do not worsen eGFR in CKD, with possible improvement in ureteral stones
- Virtual reality interventions improve gait speed and reduce pain and depressive symptoms in hemodialysis patients
- Anti-GBM disease can emerge after apparent remission of ANCA-associated vasculitis in elderly patients
- Decellularized dental pulp extracellular matrix supports stem cell behavior and tissue architecture in preclinical models
- Global PD peritonitis incidence 0.31 episodes per patient-year, with wide regional variation
- Traditional Chinese Medicine and modern multi-organ networks offer integrated perspectives on the kidney-bone axis
- Frailty assessments identify risk stratification and functional recovery predictors in patients undergoing hip arthroplasty
- Periodontitis is associated with poorer periodontal status in patients with Parkinson's disease
- FDA Approves Zortress (everolimus) for Organ Rejection Prophylaxis in Kidney and Liver Transplant
- FDA Approves Kerendia (finerenone) for CKD with Type 2 Diabetes and Heart Failure
- FDA Approves Jynarque (tolvaptan) for Autosomal Dominant Polycystic Kidney Disease
- Amino acid-based peritoneal dialysis solutions can cause chemical peritonitis mimicking bacterial peritonitis in patients
- Gut-kidney axis drives sepsis-associated AKI, review argues for microecological and neuromodulatory therapies
- Exergaming improves balance and dynamic gait ability in older adults with chronic conditions
- Endovascular arteriovenous fistula provides a safe and effective alternative to surgical arteriovenous fistula
- AVF ligation reduces left ventricular mass index by 10.92 g/m in end-stage kidney disease
- Vitamin D deficiency is associated with 33% higher odds of progression in chronic kidney disease
- Ferric citrate is non-inferior to sevelamer carbonate for phosphorus reduction in hemodialysis patients
- Alert-based CDS increases UACR testing from 11.5% to 36.0% in patients with type 2 diabetes
- Elevated glucose, chloride, and anion gap levels are associated with increased risk of acute kidney injury
- Self-management education and exercise training significantly reduce fatigue in adults on haemodialysis
- Bispecific antibodies improve progression-free survival and overall survival in patients with solid tumors
- Periodontal conditions and plaque index correlate with lower oral health-related quality of life in ESRD patients
- Salivary urea, creatinine, calcium, and pH are significantly higher in patients with chronic kidney disease
- High-protein diets increase eGFR in adults without chronic kidney disease across 22 randomized controlled trials
- Dysregulated tryptophan metabolism drives neurocognitive complications in approximately 40% of patients with chronic kidney disease
- Protein-energy wasting prevalence reaches 47.0% among patients with chronic kidney disease in Africa
- Lithium-associated nephrogenic diabetes insipidus may cause severe postoperative hypernatremia and polyuria
- Oral microbiome dysbiosis is observed in children and adolescents with chronic kidney disease
- Behavioral adaptations and choices moderate or mediate the impact of air pollution on health outcomes
- Natural products like polysaccharides and TCM formulas may modulate gut microbiota to protect renal function
- Educational interventions significantly improve knowledge and quality of life for patients on peritoneal dialysis
- Elevated acute:chronic workload ratio shows small-to-moderate injury risk link in team-sport athletes
- Acupuncture Lowers Systolic Blood Pressure in Hypertensive Adults
- Dietary fiber reduces indoxyl sulfate by 0.13 mg/dL in humans with CKD
- MASLD is associated with higher CKD prevalence and accelerated renal impairment progression
- MARS treatment significantly improves creatinine and INR levels in hepatic encephalopathy patients
- Telitacicept shows lower incidence of adverse drug reactions in patients with IgA nephropathy
- CKD-MBD medication titration is associated with serum calcium, phosphorus, and parathyroid hormone levels
- Scoring paclitaxel-coated balloon angioplasty improves 6-month target lesion primary patency by 21.2 percentage points
- Chronic kidney disease is associated with increased plaque, calculus, and gingival inflammation
- Combined nutrition and exercise improves physical performance in patients on hemodialysis
- FDA Approves Myfortic (mycophenolic acid) for Kidney Transplant Rejection Prophylaxis
- Non-invasive vagus nerve stimulation reduces monthly headache days in migraine patients
- Natural products offer multi-target renoprotective effects for metabolic, inflammatory, and oxidative stress pathways
- Chronic kidney disease prevalence of 13.7% identified across 19 African countries
- Frailty associated with higher odds of cognitive impairment in patients with chronic kidney disease
- Concurrent primary aldosteronism and micro-pheochromocytoma can coexist in patients with paroxysmal hypertension
- Inflammation and immune dysregulation drive chronic kidney disease progression and associated tissue remodeling
- Finerenone Efficacy and Safety in Patients with Chronic Kidney Disease and Glomerular Disease
- SARS-CoV-2 related microvascular thrombosis is associated with increased risk of acute kidney injury
- Vitamin D supplementation shows low certainty reductions in urinary markers for diabetic kidney disease
- FDA Approves Sodium Bicarbonate Injection for Metabolic Acidosis and Urinary Alkalinization
- Renal vascular variations do not compromise long-term outcomes in patients with complex anatomy
- KidneyTIME digital intervention improves knowledge and listing behaviors but not donor inquiries in kidney transplant candidates
- Inclisiran reduces LDL cholesterol by up to 54.7% in patients with atherosclerotic cardiovascular disease
- Dapagliflozin reduces proteinuria and blood pressure but does not improve eGFR in CAD patients
- Respiratory viral coinfections reshape immune signaling and granuloma stability in Mycobacterium tuberculosis infections
- Acupuncture combined with exercise rehabilitation improves cardiac function and walk distance in heart failure
- Higher Systolic Blood Pressure Time in Target (SBP TTR) associated with 10% lower risk of poor kidney outcomes
- Delayed graft function shows no significant association with BK polyomavirus DNAemia in kidney transplant recipients
- Risk prediction models show 0.83 discriminatory performance for identifying malnutrition in dialysis patients
- Residential greenness is associated with reduced low birth weight risk in maternal populations
- Spontaneous regression observed in a patient with cystic renal cell carcinoma
- Bendamustine and rituximab treatment for Waldenström macroglobulinemia with renal AL amyloidosis shows hematologic response
- Oral squamous papilloma with koilocytic changes may occur in cases of chronic denture-associated irritation
- Precision nutrition offers dynamic optimization for managing patients with chronic liver disease through individualized metabolic profiles
- FDA Approves Terlivaz (terlipressin) for Hepatorenal Syndrome with Rapid Kidney Function Decline
- Intraoperative anesthesia handovers are associated with increased risk of mortality and morbidity in surgical patients
- Adolescent physical activity is associated with improved mental and physical health in early adulthood
- Cystatin C shows good diagnostic performance with an AUC of 0.88 for early detection of SA-AKI
- Gut microbiota dysbiosis and microbial metabolites impair renal function in sepsis-associated acute kidney injury
- ILC dysregulation and gut microbiota dysbiosis may drive kidney disease via the microbiota-gut-kidney axis
- FDA Approves Feraheme (ferumoxytol) for Iron Deficiency Anemia in Adults
- Kidney transplantation reduces left-ventricular mass index by 22 g/m² in end-stage kidney disease
- Chronic kidney disease linked to shorter leukocyte telomere length in meta-analysis
- Education and behavior interventions reduce burden for CKD caregivers in a systematic review
- Gut dysbiosis contributes to CKD complications via interconnected pathways, though mechanistic validation remains incomplete
- Pyrethroid insecticide exposure linked to acute kidney injury in a 55-year-old male
- Systematic review and meta-analysis finds roxadustat improves hemoglobin in peritoneal dialysis patients
- Robotic ISR shows better anal function and fewer complications than laparoscopic approach
- Mini review of Explainable AI for kidney stone segmentation in resource-constrained settings
- Narrative review explores gut-kidney axis in chronic kidney disease progression
- Digital decision support tools showed parallel improvements with no between-group differences in kidney outcomes among adults with chronic kidney disease in Chinese primary care centers
- Meta-analysis links suprarenal aortic repair techniques to higher risk of permanent renal dialysis in AAA patients
- HIF-PHIs alter lipid profiles in CKD patients but show no cardiovascular mortality difference
- Pentoxifylline Improves Kidney Function and Reduces Inflammation in CKD
- Systematic review confirms clip anastomosis improves one and two year primary patency rates for arteriovenous fistula creation compared to suture methods
- Arterioarterial grafts show high patency in hemodialysis patients
- Review of environmental exposures in agricultural communities with chronic kidney disease of unknown cause
- Amiloride and hydrochlorothiazide affect metabolites and ammonium excretion in CKD patients
- Nephrometry Scores Show Limited Discrimination for Adverse Outcomes After RAPN in Larger Renal Tumors
- Pre-admission statin use linked to better 30-day outcomes after aneurysmal SAH
- Kidney-directed SBRT shows modest renal function decline in inoperable patients
- Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients
- Systematic review and meta-analysis of health coaching interventions in chronic kidney disease patients
- Meta-analysis shows systemic heparinization reduces early patency loss in adult AVF or graft placement
- Meta-analysis shows active surveillance and ablative therapy for small renal masses have comparable cancer-specific survival
- Systematic Review and Meta-Analysis Links α-Klotho to Frailty and Bone Health in Aging
- Systematic review and meta-analysis of MRAs in dialysis patients shows reduced nonfatal CVD events but elevated hyperkalemia and gynecomastia risks
- Pre-treatment body composition and acute kidney disease risk in head and neck cancer patients treated with cisplatin
- Mini Review Covers Complement Pathways in Kidney Diseases and Injuries
- Narrative review discusses renal risks in inflammatory bowel disease patients
- Guideline narrative review discusses diabetes risks from immunosuppressive therapy in kidney transplant recipients
- White blood cell indicators predict acute kidney injury in critically ill advanced colorectal cancer patients
- Comprehensive salivary gland–sparing helical tomotherapy reduces radiation-induced xerostomia in nasopharyngeal carcinoma patients
- Observational study links cutaneous microvascular function to chronic kidney disease severity
- Individual-participant data meta-analysis shows blood-pressure lowering reduces cardiovascular risk in CKD and non-CKD populations
- Circulating SVEP1 Protein Associated With Major Adverse Cardiovascular Events in Hemodialysis Patients
- Cross-sectional study links declining nephron number to CKD stage in diabetic nephropathy
- High-altitude ICU study finds 21% AKI incidence in neurocritical patients
- Systematic review and meta-analysis shows dapagliflozin increases hemoglobin in chronic kidney disease patients
- Observational review of layered data models improves DKD risk detection in type 2 diabetes cohorts
- Meta-analysis identifies risk factors for patency loss after PTA in hemodialysis patients
- Preclinical analysis of gnomAD and ClinVar databases on ADPLD variant frequencies
- Preclinical evaluation of five LLMs on nephrology multiple-choice questions
- Endoscopic ulceration and multi-segment GI involvement linked to longer hospitalization in IgA vasculitis
- Higher RAR linked to increased in-hospital mortality in infants with congenital heart disease
- Dyslipidemia linked to poorer renal survival in primary IgA nephropathy patients
- Pilot RCT tests digital inclusion intervention for adults with chronic kidney disease
- Single-centre observational study on hemodialysis duration and outcomes in end-stage renal disease
- Meta-analysis of nutrition education in adult dialysis patients shows improved knowledge and quality of life
- Real-world analysis finds 34% grade 3-4 adverse events in mRCC patients on immune-based combos
- Liuwei Dihuang Pills combined with conventional medicine reduces albuminuria in early diabetic nephropathy
- Hybrid EDF intraocular lens matches monofocal for distance, improves intermediate and near vision
- Rectal Misoprostol Associated With Reduced Fever and Infection After Laparoscopic Myomectomy
- Mini-review links insulin to worse COVID-19 outcomes in type 2 diabetes patients
- Physical exercise reduces all-cause mortality and improves outcomes in chronic kidney disease patients
- Jyothi Trataka yoga practice improves dry eye symptoms in adults with mild-to-moderate condition
- Systematic review of dry needling in sports athletes shows short-term pain relief but uncertain performance benefits
- Mental health syndemics reduce ART adherence and impair viral suppression in people living with HIV
- Physical activity improves cardiopulmonary function and general health in individuals with Sjögren's syndrome
- Hungarian app use associated with lower reported antibiotic, antipyretic, and doctor visit use in children
- Systematic review links gut microbiota dysbiosis to CKD-MBD, RA, OA, and OP pathogenesis
- Podocyte morphometrics correlate with albuminuria and eGFR decline in IgA nephropathy cohort
- UK retrospective cohort study of tolvaptan prescribing in ADPKD reveals significant variation in initiation and substantial national costs
- Electrolyte homeostasis adaptations in pregnancy require distinct norms to avoid misclassifying abnormalities and delaying care
- Vim-targeted tremor surgery shows substantial tremor improvement across various targeting approaches
- Urinary podocin and nephrin show poor short-term prediction of DKD progression in type 2 diabetes
- Novel nomogram predicts long-term survival after TIPS in decompensated cirrhosis
- Retrospective study identifies predictors for dialysis access steal syndrome in ESRD patients
- Hispanic/Latinx adults with IgAN show rapid eGFR decline and high kidney event rates in retrospective cohort
- Serenity therapy reduces symptoms and improves coping in geriatric hemodialysis patients
- Sweden saw a five-fold increase in vibration check-ups among exposed workers between 2016 and 2022
- Systematic review shows high CKD prevalence and undiagnosed cases among hypertensive patients in Arab countries
- Phase 2a trial of dazodalibep plus belatacept shows 25% acute rejection rate in kidney transplant patients
- Hybrid machine learning model predicts CKD progression in Stage 3 adults using longitudinal data
- Swiss IgAN cohort shows 43% ESKD progression, high immunosuppressive use over 8-year follow-up
- Meta-analysis finds higher circulating stearic acid associated with lower CKD risk in 18,193 adults
- FDA Approves Vafseo (vadadustat) for Anemia Due to Chronic Kidney Disease in Adults on Dialysis
- Urinary myoglobin-to-creatinine ratio identified as potential biomarker for chronic benign proteinuria
- Environmental factors predict CKDu prevalence with 85% accuracy in Sri Lankan observational study
- Survey reports on percentage of US adults with kidney disease; specific findings not provided
- Genetic testing identified positive findings in 24% of CKD patients and changed management in most cases
- Endothelial dysfunction prevalent in PCI patients; 33.7% developed contrast-associated AKI
- Narrative review supports regional anesthesia and targeted non-opioids for chronic post-surgical pain and opioid use
- Shift work associated with 43% higher odds of chronic kidney disease in meta-analysis
- Omega-3 fatty acids may reduce CRP in haemodialysis patients, but evidence is limited
- Metabolic syndrome associated with higher cardio-renal risk in kidney transplant recipients
- Narrative review describes inflammatory and lipotoxicity mechanisms in obesity-related chronic kidney disease
- NGAL biomarker shows promise for AKI detection and peritoneal dialysis-related peritonitis management
- Standardized sonographic parameters POV and PVD show association with chronic injury in kidney transplant dysfunction
- Case report: Deep tissue massage linked to renal artery occlusion and kidney infarction in healthy man
- Xenotransplantation shows potential for end-stage kidney disease but remains experimental
- Obinutuzumab induced remission in FSGS patient after rituximab failure in case report
- Cystinosis patients show larger neural conflict monitoring differences versus controls in observational study
- FDA Approves Ringer's In Plastic Container (Ringer's solution) for parenteral replacement of extracellular fluid and electrolyte losses
- Case report: Liver transplant recipient on dialysis for over 10 months recovered kidney function
- Acthar studied in FSGS patients undergoing renal transplantation to measure recurrence rate
- CFZ533 vs Tacrolimus in Kidney Transplant: Phase 2 Study Terminated After Interim Analysis
- Atorvastatin evaluated for dyslipidemia in children with steroid-sensitive nephrotic syndrome
- TRACK trial to assess low-dose rivaroxaban for MACE in advanced CKD/dialysis patients
- PALaDIN Study: High vs. Low Dose Iron in Peritoneal Dialysis Patients
- Phase 2 Study Evaluates Abatacept for Kidney Transplant Recipients
- Phase 2 Study Evaluates Frexalimab, Brivekimig, Rilzabrutinib in FSGS and MCD
- Phase 2 Study: ManNAc for FSGS Shows Promise in Reducing Proteinuria