Bayesian network meta-analysis compares exercise modalities for systemic inflammation in postmenopausal women
Resistance training reduces inflammation in postmenopausal women
This Bayesian network meta-analysis of 39 RCTs evaluated the comparative efficacy of aerobic, resistance, HIIT, and combined training on inf…
New evidence suggests different types of exercise target different inflammatory markers in postmenopausal women with obesity.
Meta-analysis shows exercise interventions impact TNF-alpha but not IL-6 or CRP in older adults
Exercise may lower specific inflammation markers in older adults
This meta-analysis of randomized controlled trials evaluated the effect of exercise interventions on serum inflammatory biomarker levels in …
New evidence shows that exercise interventions can significantly reduce certain inflammatory markers in older adults facing frailty or sarco…
Meta-analysis compares infection rates of teclistamab in clinical trials and real-world evidence
Teclistamab linked to higher infection rates in some patients
This meta-analysis of 714 patients evaluates the incidence of infections in relapsed/refractory multiple myeloma treated with teclistamab. T…
New data shows that patients using teclistamab for multiple myeloma may face a significant risk of developing various types of infections.
Case report and literature review of severe adverse reactions following pucotenlimab treatment
New drug treatment linked to severe neurological reactions
This case report and literature review describes severe adverse reactions following treatment with pucotenlimab in a patient with advanced b…
A single patient facing advanced breast cancer experienced life-threatening neurological symptoms after receiving the drug pucotenlimab.
Inactivated SARS-CoV-2 vaccine dosing schedules and antibody responses in adults aged 60 to 80 years
Older adults get better protection with the right vaccine booster timing
This prospective cohort study of 450 adults aged 60 to 80 years in China examined three inactivated SARS-CoV-2 vaccine dosing schedules. The…
New data shows older adults get the best protection when they receive specific vaccine boosters at the right time.
Systematic review identifies dual role of NLRP3 inflammasome in sepsis induced immune dysregulation
NLRP3 activation plays a dual role in sepsis
This systematic review examines the role of NLRP3 inflammasome activation and modulation in sepsis. The authors synthesize evidence showing …
A review of research shows that a specific protein complex helps drive both inflammation and immune suppression during sepsis.
Probiotic co-administration with berotralstat improves GI tolerability in HAE patients
Probiotics may help manage side effects of HAE treatment
This pilot case series from six Italian centers evaluated probiotic co-administration with berotralstat in 25 adolescents and adults with he…
New early treatment steps for hereditary angioedema might reduce monthly attacks while keeping stomach issues to a minimum.
Th17/Treg ratios and cytokine levels associated with infection risk after kidney transplantation
Immune cell levels may predict kidney transplant infection risk
This cohort study of 200 kidney transplant recipients examined the relationship between Th17/Treg cells and cytokine levels with post-surgic…
Certain immune cell patterns and protein levels could help doctors predict which kidney transplant recipients are most at risk for infection…
Systematic review and meta-analysis of stem cell therapy for dry eye in Sjögren's syndrome
Stem Cell Therapy Eases Dry Eye in Sjögren’s Syndrome Patients
This systematic review and meta-analysis evaluated stem cell therapy for patients with dry eye syndrome caused by Sjögren's syndrome. The an…
New analysis shows stem cell therapy eases dry eye pain and improves tear flow for people with Sjögren’s syndrome.
Review examines thoracic radiotherapy combined with chemoimmunotherapy for extensive-stage small cell lung cancer patients
Doctors are still figuring out the best way to treat extensive-stage small cell lung cancer.
This review examines the use of thoracic radiotherapy combined with chemoimmunotherapy in patients with extensive-stage small cell lung canc…
A review notes that while combining radiation with chemotherapy and immune therapy helps some patients, the best approach is still being stu…
Narrative review examines links between periodontitis and systemic disorders without claiming causation
Oral inflammation may link to systemic disorders, but evidence is not definitive
This narrative review explores the relationship between oral inflammatory diseases, particularly periodontitis, and various systemic disorde…
A narrative review suggests oral inflammatory diseases like periodontitis are associated with systemic disorders, though the evidence is not…
Systematic review outlines theoretical basis for early warning and personalized treatment in IgAVN
New blood tests could replace kidney biopsies for children with IgAVN
This systematic review summarizes current research progress regarding Immunoglobulin A vasculitis nephritis management and diagnosis. The au…
A new review shows blood tests might soon replace painful kidney biopsies for kids with IgAVN