Gastroenterology

All Gastroenterology Articles

• Patients with Irritable Bowel Syndrome have 2.57 times higher odds of undergoing cholecystectomy
• HBsAg-positive kidneys confer similar allograft and patient survival in kidney transplant recipients
• Probiotics reduce infection rates and inflammatory markers in patients with colorectal cancer
• Mucosal immune ecology model of necrotizing enterocolitis suggests precision prevention based on developmental timing
• Dendritic cells bridge innate and adaptive immunity but suffer dysfunction during sepsis-induced immunoparalysis
• Personalized risk information improves screening intent for colorectal cancer among average risk patients
• Atezolizumab and bevacizumab plus TACE improves TACE-PFS to 11.30 months versus 7.03 months
• Baseline anti-HBc positivity does not impact 3-year PFS or OS in HBsAg-negative DLBCL
• Computer-aided quality assurance improves adenoma and advanced adenoma detection during colonoscopy
• Combined US and MRI model yields significantly higher diagnostic accuracy for predicting microvascular invasion in HCC
• EGFR inhibitors show higher response rates but no survival advantage over bevacizumab in CRLM
• Reduced circulating tumor cells correlate with improved progression-free survival and overall survival in colorectal cancer
• Prophylactic HIPEC improves peritoneal metastasis-free survival and disease-free survival in locally advanced colorectal cancer
• Hepatectomy plus splenectomy improves overall survival and recurrence-related survival in patients with hepatocellular carcinoma
• Germline multigene panel testing identifies pathogenic variants in 15.2% of colorectal cancer patients
• GCSF shows survival benefit in alcohol-related hepatitis, but evidence remains uncertain
• Higher intrapancreatic fat deposition is associated with greater liver fat excess in Type 2 Diabetes
• RPAD salvage achieves 12-month remission in TAFRO syndrome with autoimmune background
• Implementation science methods can bridge the 17 year research-practice gap in infant neuromotor development
• Total glucosides of paeony may interrupt the gut-liver axis cycle in liver cirrhosis
• Six amino acid metabolism biomarkers distinguish periodontitis from controls in early in silico and tissue validation
• Environmental factors influence oral tissue alterations through oxidative stress, inflammation, and microbial dysbiosis
• Molecular hydrogen may influence gut microbiota and intestinal barrier integrity in metabolic and gastrointestinal disorders
• Diverse strategies for biofilm control and caries-risk mitigation show varying success in clear aligner interfaces
• mpMRI markers of liver disease are associated with lower health-related quality of life in MASH
• Natural compounds targeting PPARγ provide preclinical mechanistic support for ulcerative colitis treatment
• Rifaximin has the clearest guideline-supported role for IBS with diarrhea among microbiota-directed interventions
• Eight-Week Sofosbuvir-Velpatasvir Matches Twelve-Week Course in Non-Cirrhotic Hepatitis C
• L. reuteri DSM 17938 modestly shortens pediatric acute gastroenteritis diarrhea by 0.68 days
• Pre-clinical evidence suggests polyunsaturated fatty acids may influence gut microbiota and mucosal immunity in IBD
• Refractory ascites significantly reduces social, mental, and physical functioning in patients with advanced chronic liver disease
• Crohn's disease patients exhibit reduced fungal alpha diversity compared to healthy controls
• Intestinal bacteria and their products modulate Toll-like receptor signaling in colorectal cancer development
• Traditional Chinese medicine components show short-term efficacy signals in ulcerative colitis but lack established clinical evidence
• 15 germline loci associated with hepatocellular carcinoma identified across multiple ancestries
• Sugammadex reduces recovery time after surgery by 6.66 minutes compared to anticholinesterase agents
• Neoadjuvant radiation therapy reduces local recurrence risk but not overall survival in upper rectal cancer
• Laparoscopic approach is associated with lower 30-day mortality in nonagenarians undergoing colorectal resection
• Fungal dysbiosis is associated with altered community structures and immune remodeling in several gastrointestinal cancers
• Early liver transplantation shows no significant difference in mortality compared to standard liver transplantation
• Thermal ablation shows no difference in survival but lower complication rates than liver resection
• Degradable Starch Microspheres TACE shows no significant improvement in survival for hepatocellular carcinoma
• Dietary factors and zonulin influence intestinal barrier integrity and mucosal immune activation
• Moxibustion associated with increased microbial richness and reduced pro-inflammatory mediators in preclinical animal models
• Percutaneous catheter drainage outperforms needle aspiration for liver abscess clinical success
• TIPS combined with embolization reduces rebleeding risk in patients with decompensated liver cirrhosis
• Antibiotic exposure is associated with an increased risk of developing Irritable Bowel Syndrome
• Fusobacterium nucleatum promotes chronic inflammation and is associated with colorectal cancer and pregnancy complications
• Higher histologic liver fibrosis stages correlate with increased risk of cirrhosis and hepatic decompensation
• Elafibranor shows a broadly reassuring safety profile in patients with primary biliary cholangitis
• ASA score of 3 or higher is an independent risk factor for UTI in rectal cancer patients
• CADe-assisted colonoscopy did not increase adenoma detection rate compared with conventional colonoscopy
• CADe colonoscopy fails to raise adenoma detection overall; benefit seen only in low performers
• CAD EYE computer-aided assistance did not significantly improve adenoma detection rates in Lynch syndrome patients
• Resmetirom Improves MASH Resolution and Fibrosis in F2-F3 Patients
• Watch-and-wait after total neoadjuvant therapy shows comparable oncologic outcomes to surgery for rectal cancer
• Evaluating Volumetric FDG-PET Parameters for Identifying Microsatellite Instability in Colorectal Cancer
• EUS-PPG Shows Strong Correlation With Invasive Portal Pressure, but Agreement Remains Wide
• Aspirin does not significantly improve disease-free survival or overall survival in colorectal cancer patients
• Placebo Arms Show 13.09 Cirrhosis Events per 100 Person-Years in Fibrotic MASH
• CT Derived Visceral Fat Area as a Predictor of Anastomotic Leakage in Rectal Cancer
• Intersphincteric resection reduces local recurrence and improves five-year survival in lower rectal cancer
• Statins reduce overall mortality and hepatic venous pressure gradient in patients with liver cirrhosis
• Modified endoscopic mucosal resection offers comparable histologic efficacy to ESD for rectal neuroendocrine tumors
• Optimal ELF cutoffs identify significant fibrosis and cirrhosis in patients with MASLD
• Mediterranean diet reduces BMI and triglycerides in patients with NAFLD and MASLD
• Nonbioartificial liver support reduces 28-day mortality in acute-on-chronic liver failure by 28% compared to standard therapy
• Non-combustible nicotine products may reduce smoke-related toxicants but sustain nicotine dependence in users
• Hepatic macrophage metabolic reprogramming and bidirectional signaling dictate the balance between liver injury and regeneration
• AI tongue image analysis shows variable accuracy for gastric cancer screening
• Dietary management serves as a supportive tool for symptom relief in Small Intestinal Bacterial Overgrowth
• White-light colonoscopy sensitivity for adenomas is 0.54 with lower sensitivity for smaller lesions
• Lactobacillus-supplemented therapy increases Helicobacter pylori eradication success by 10% and reduces adverse events
• Layered risk-based biosafety measures and validated specimen pathways improve safety for healthcare workers and patients
• Salivary and oral signatures show potential as non-invasive biomarkers for pediatric H. pylori infection
• FDA Approves Glucagon for Injection as Diagnostic Aid During Radiologic Examinations
• Nurse-led pathways for loneliness and social isolation in older adults show heterogeneous clinical outcomes
• Layered host-directed and regenerative strategies complement conventional control for ASF and swine influenza
• Gut microbiota and nutrition proposed as integrated targets in colorectal cancer cardio-oncology
• Targeted and biological therapies offer potential to reduce disease activity and organ damage in SLE
• MASLD in people living with HIV may represent a distinct immunometabolic condition with rising prevalence
• Global HBsAg prevalence 3.2% in nurses, with 5.6% in Africa and 3.6% in LMICs
• Transcriptomic analysis identifies 846 genes and key pathways associated with MASLD fibrosis progression
• Mycobacterium avium subsp. paratuberculosis may contribute to Crohn's disease through complex pathogenic mechanisms
• Elevated preoperative SIRI correlates with worse survival and progression in patients with bladder cancer
• Mesenchymal stem cells alleviate liver injury and inflammation in preclinical alcoholic hepatitis models
• Robotic liver resection reduces intraoperative blood loss and conversion rates compared to laparoscopic resection
• Natural products like Aloe vera and guar gum show significant improvements in diarrhea management
• Bioactive components of medicinal-food homology substances show marked efficacy in treating functional constipation
• Microbiota-directed interventions reduce hospital stay and infection risk in acute pancreatitis patients
• Seaweed sulfated polysaccharides modulate gut microbiota and mucosal barrier in inflammatory bowel disease
• TZ84-based hepatitis A vaccine shows higher seroconversion rates and GMCs than HM175-based vaccine
• Gut microbiota influence innate immune signaling and promote colibactin-associated mutational signatures in colorectal cancer
• Microbial exopolysaccharides improve intestinal health and gut microbiome modulation in 28 in vivo studies
• Epigenetic mechanisms provide a molecular interface between genetic susceptibility and immune dysregulation in asthma
• Dietary macronutrients influence intestinal barrier integrity and immune responses in inflammatory bowel disease
• Extracellular vesicle-based therapies show potential for tissue repair and barrier restoration in inflammatory bowel disease
• Impact of RAS and BRAF Mutation Status on Immune Checkpoint Inhibitor Efficacy
• Cocaine use is associated with higher mortality and surgical rates in ischemic colitis cases
• Aerosolized liposomal amphotericin B provides strongest evidence for invasive pulmonary aspergillosis prophylaxis in high-risk patients
• Antenatal or intrapartum N-acetylcysteine may reduce severe neonatal morbidity and bronchopulmonary dysplasia rates
• Impact of Mechanical Bowel Preparation and Oral Antibiotics on Rectal Surgery Outcomes
• Evaluating High-Dose Vitamin D3 Supplementation in Metastatic Colorectal Cancer Treatment Regimens
• Huangqi Guizhi Wuwu Decoction reduces grade 2 or higher OIPN from 38.6% to 21.3%
• Phase 2 Trial Evaluating Zalfermin and Semaglutide Combinations for Metabolic Dysfunction Associated Steatohepatitis
• Doublet-LC TNT improves 3-year DFS to 74.8% compared to 66.0% in high-risk rectal cancer
• rs2896019 G allele associated with 51% increased risk of MASLD susceptibility
• Clinical trials for MASLD show limited racial and ethnic diversity despite increasing Hispanic enrollment
• EUS-guided cyanoacrylate injection reduces rebleering rates compared to direct endoscopic cyanoacrylate for gastric varices
• Multidrug-resistant pathogens are prevalent in cirrhosis with higher rates in lower-middle-income countries
• Impact of Visceral Obesity on Surgical Outcomes in Colorectal Cancer Resection
• Multimodal preoperative prehabilitation improves 6-minute walk distance in patients with colorectal cancer
• Major HCV genotypes G1, G2, and G3 account for 98.02% of infections in FSU regions
• Efficacy of High-Intensity Interval Training and Moderate-Intensity Continuous Training in MASLD
• Local therapies for liver, lung, and locoregional recurrence improve survival in pancreatic ductal adenocarcinoma
• 19 G needles provide superior tissue adequacy and histological diagnosis compared to 22 G needles
• PET/CT Matches MRI Sensitivity but Boosts Specificity in Rectal Cancer
• HBsAg prevalence 9.98% in Cameroon, higher-risk groups 12.70%
• Telmisartan leads to modest fasting blood sugar reduction in patients with MASLD
• Prevotella exhibits dual pro-tumorigenic and anti-tumorigenic roles in gastrointestinal cancer progression
• Immune markers correlate with clinical outcomes following nucleos(t)ide analogue withdrawal in chronic hepatitis B
• Precision glucocorticoid dosing remains investigational; genetic markers not yet clinically actionable
• Skin lesions typically precede spinal arthritis in patients with follicular occlusion triad and spondyloarthritis
• Gut-brain axis dysregulation links Crohn's disease activity with heterogeneous mood improvements from emerging therapies
• Infliximab treatment in pediatric IBD is associated with specific microbial shifts rather than uniform diversity recovery
• Pediatric GERD and proton pump inhibitor exposure are associated with reduced microbial diversity
• Traditional Chinese Medicine potentially influences gastrointestinal motility and gut microbiota in Irritable Bowel Syndrome
• Immune checkpoint inhibitors in rectal cancer: balancing anti-tumor effects against ICI-associated colorectal injury
• Gut microbiota alpha diversity increases during the first year of life in infants and toddlers
• FABP2 serves as a sensitive biomarker of intestinal mucosal injury in inflammatory bowel disease
• FDA Approves Iqirvo (elafibranor) for Primary Biliary Cholangitis
• ALPPS yields fastest liver growth but worse 1-year DFS than PVE in meta-analysis
• Dietary quality and precision nutrition may mitigate the vegetarian hepatoprotection paradox in MASLD patients
• MRI-based radiomics models predict tumor budding grade in rectal cancer with 0.88 AUC
• Durvalumab plus tremelimumab median PFS was 5.4 months in HIMALAYA eligible patients
• PCE with indigo carmine increases adenoma detection rate to 51.5% compared to 34.5% for WLE
• CADe improves adenoma detection rate from 44% to 63% in standard-detector endoscopists
• Thromboembolic events cost 2.5-fold more per event than bleeding after high-risk endoscopy
• Itopride 150 mg once daily matches 50 mg thrice daily in functional dyspepsia
• Higher tolerance of ambiguity correlates with higher perceived benefit in colorectal cancer screening
• FIT positivity and neoplasia detection rates peak in the first round of screening programs
• Terminal ileal intubation provides a 0.28% diagnostic yield for clinically significant pathology in asymptomatic patients
• Pelvic peritoneum closure reduces risk of severe postoperative complications in rectal cancer patients
• Carvedilol and endoscopic variceal ligation show similar efficacy for preventing variceal bleeding in cirrhosis
• Steatotic liver disease prevalence reaches 57.75% in patients with primary hypobetalipoproteinemia
• Semaglutide improves MASH resolution (OR 3.48) and liver fat reduction in MASLD patients
• Statin therapy reduces hepatocellular carcinoma risk and hepatic decompensation by 46% in chronic liver disease
• Multidisciplinary team management reduces mortality risk in patients with hepatobiliary and pancreatic malignancies
• Transanal transection and single-stapled anastomosis reduces anastomotic leakage risk in rectal cancer surgery
• Elevated IGF-I levels correlate with increased risk of colorectal adenoma and colorectal cancer
• Intermittent fasting reduces liver fat content and CAP scores in patients with MASLD
• Multidrug-resistant bacterial infections are prevalent among hospitalized patients with cirrhosis
• Viscoelastic Testing Cuts Transfusions in Cirrhosis Procedures
• Heterozygous SERPINA1 genotypes are associated with increased liver disease risks in Alpha-1 Antitrypsin Deficiency
• Organ transplantation impacts oral microbiome composition and bacteria associated with periodontal inflammation
• Bismuth quadruple and concomitant regimens achieve >85% H. pylori eradication amid rising clarithromycin resistance
• FDA Approves Rezdiffra (resmetirom) for Noncirrhotic NASH with Moderate to Advanced Fibrosis
• Acidic microenvironments reprogram immune cells via pH sensors, driving tissue injury
• Subcutaneous semaglutide more than doubles the likelihood of NASH resolution without fibrosis progression
• New guideline tool curates 51 instruments for theory-driven implementation science assessment
• Intensive CV management reduces cIMT progression in RA patients without hepatic steatosis
• Robotic hepatectomy is safe and offers lower blood loss and shorter hospital stays than open surgery
• Probiotics modestly reduce pain intensity and weekly episodes in children with abdominal pain disorders
• Tissue-resident memory T cells drive disease relapse after biologic and JAK inhibitor discontinuation in atopic dermatitis
• CD4+ T cells and Tim-3 regulate immune responses and cytokine-mediated injury in severe pediatric pneumonia
• MAGIC algorithm and multi-omics approaches facilitate precision management of gastrointestinal acute graft-versus-host disease
• Tryptophan metabolism pathways like IDO and TDO2 influence immune cell function in end-stage liver disease
• Training programs improve healthcare professional confidence and competence in video and text based consultations
• Trained immunity drives mucosal inflammation and recurrence in patients with chronic rhinosinusitis
• Physical exercise may attenuate inflammation and alveolar bone loss in patients with periodontitis
• Google NotebookLM achieves 99.77% critical accuracy and 89.3% workflow time reduction in systematic review data extraction
• Linaclotide combined with polyethylene glycol significantly improves bowel preparation quality in patients with constipation
• Robustly generalizable gut microbiome signatures are identified in patients with colorectal cancer regardless of age
• Antibiotic exposure is associated with an 18.7% higher risk of gastrointestinal cancers
• Gut microbiome biomarkers show AUROC of 0.89 for differentiating colorectal cancer from controls
• Prevention interventions may reduce e-cigarette ever use while cessation-focused efforts likely reduce current adolescent usage
• Microbiota-immune-enteric nervous system interactions provide a framework for understanding functional and slow-transit constipation
• Upadacitinib 15 mg daily improves pruritus and skin sclerosis in a case of refractory lichen sclerosus
• Splenic stiffness measurement shows high sensitivity for varices in children with non-cirrhotic portal hypertension
• Twenty-two factors across five ecological levels are significantly associated with fear of cancer recurrence
• MELD and MELD-Na demonstrate higher specificity than Maddrey discriminant function for alcoholic hepatitis mortality
• Persistent descending mesocolon increases operative time and conversion rates in colorectal cancer surgery
• Endoscopic investigation for iron deficiency anemia reveals 52.0% prevalence of normal upper gastrointestinal findings
• Metabolic and bariatric surgery achieves 70% steatohepatitis remission in patients with MAFLD
• Hepatic vein occlusion with portal vein embolization yields 24.5% greater future liver remnant increase
• JAK inhibitors are associated with higher hepatitis B virus reactivation rates than IL-12/23 or IL-17 inhibitors
• Immune crosstalk between innate and adaptive compartments drives inflammatory mechanisms in MASLD and MASH progression
• Schroth combined with sensory integration training shows greatest Cobb angle reduction in adolescent idiopathic scoliosis
• Plant-derived exosome-like nanoparticles mitigate weight loss and improve colon length in ulcerative colitis models
• The bile acid-gut microbiota-vitamin D axis may influence pathogenesis of biliary atresia
• Axial psoriatic arthritis is associated with significantly lower HLA-B27 positivity than axial spondyloarthritis
• Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
• Anthraquinone laxatives may produce active metabolites via gut microbiota conversion leading to melanosis coli
• Long COVID causes consistent long-term deterioration in physical functioning, vitality, fatigue, and respiratory distress
• Astragalus membranaceus derivatives restore immune tolerance and homeostasis in digestive system diseases
• Laparoscopic partial hepatectomy provides definitive diagnosis and treatment for large atypical hepatic lesions in adolescents
• Lower liver-expressed TRIB1AL levels are associated with reduced liver fat and cardiovascular risk
• Infliximab may offer clinical improvement and wound reduction in non-Crohn's disease related fistulas
• Acupuncture modulates the microbiota-gut-brain axis to remodel microbial structure in patients with irritable bowel syndrome
• Reduced Shannon index indicates lower alpha-diversity in the gut microbiota of patients with primary biliary cholangitis