Terminal ileal intubation provides a 0.28% diagnostic yield for clinically significant pathology in asymptomatic patients
Colonoscopy technique shows low yield for finding Crohn's disease
This meta-analysis of 25,659 asymptomatic adults undergoing colonoscopy found that terminal ileal intubation (TII) yields only 0.28% for cli…
A large review of over 25,000 procedures shows that extra checks in the small intestine rarely find significant issues like Crohn's disease.
Pelvic peritoneum closure reduces risk of severe postoperative complications in rectal cancer patients
Pelvic Peritoneum Closure May Reduce Severe Rectal Cancer Complications
This meta-analysis of 2753 patients found that pelvic peritoneum closure (PC) significantly reduced the risk of severe postoperative complic…
Closing the pelvic peritoneum during rectal cancer surgery may lower the risk of severe complications while potentially improving bowel func…
Higher tolerance of ambiguity correlates with higher perceived benefit in colorectal cancer screening
How your comfort with uncertainty affects colorectal cancer screening
This secondary analysis of a cluster randomized clinical trial involving 448 older adults found that higher tolerance of ambiguity was assoc…
People who are more comfortable with medical uncertainty feel more confident in the benefits of colon cancer screenings.
FIT positivity and neoplasia detection rates peak in the first round of screening programs
Consistent screening shows higher detection rates for colorectal cancer
This meta-analysis of 24 studies evaluated FIT performance across multiple rounds in organized screening programs. Findings indicate that FI…
Regularly participating in stool tests may improve the chances of finding early signs of colon cancer and precancerous growths.
Multidisciplinary team management reduces mortality risk in patients with hepatobiliary and pancreatic malignancies
Multidisciplinary teams linked to better outcomes for pancreatic and liver cancers
This meta-analysis of 70,294 patients found that multidisciplinary team (MDT) management significantly reduced mortality risk in both pancre…
A large review suggests that coordinated team care can improve survival rates and reduce complications for patients with complex liver and p…
Multidrug-resistant bacterial infections are prevalent among hospitalized patients with cirrhosis
Analysis shows high rates of drug resistant infections in cirrhosis
This meta-analysis examined the prevalence of multidrug-resistant bacterial infections in hospitalized patients with cirrhosis. The findings…
Over one-third of hospitalized patients with liver cirrhosis face infections from bacteria that are hard to treat with standard medications.
Transanal transection and single-stapled anastomosis reduces anastomotic leakage risk in rectal cancer surgery
New data shows safer stitching methods for rectal cancer surgery
This Bayesian network meta-analysis of 2710 patients evaluated various anastomotic techniques for rectal cancer following total mesorectal e…
A new analysis suggests that specific suturing techniques can significantly lower the risk of leaks after rectal cancer surgery.
Carvedilol and endoscopic variceal ligation show similar efficacy for preventing variceal bleeding in cirrhosis
Comparing Carvedilol and Endoscopic Procedures to Prevent Bleeding in Liver Cirrhosis
This meta-analysis of randomized controlled trials involving 1385 patients found no significant difference between carvedilol and endoscopic…
Doctors are looking at whether the drug carvedilol works as well as endoscopic procedures to stop dangerous bleeding in patients with liver …
Steatotic liver disease prevalence reaches 57.75% in patients with primary hypobetalipoproteinemia
High Prevalence of Fatty Liver Disease in Primary Hypobetalipoproteinemia
This meta-analysis of 462 individuals identifies a pooled steatotic liver disease (SLD) prevalence of 57.75% in those with primary hypobetal…
Over half of people with primary hypobetalipoproteinemia (HBL) show signs of fatty liver disease, regardless of their usual heart health ris…
Semaglutide improves MASH resolution (OR 3.48) and liver fat reduction in MASLD patients
Semaglutide helps resolve liver inflammation in patients with MASH
This meta-analysis of 1908 patients with MASLD and MASH found that semaglutide significantly improved MASH resolution (OR 3.48) and reduced …
New data shows semaglutide can reduce liver fat and inflammation for people with fatty liver disease, though results on scarring vary.
Viscoelastic Testing Cuts Transfusions in Cirrhosis Procedures
New testing method reduces blood transfusions for liver patients
Meta-analysis finds VET-guided transfusions reduce blood product use without raising bleeding risk in cirrhotic patients undergoing procedur…
A new testing method helps patients with cirrhosis receive fewer blood transfusions during invasive procedures without increasing their risk…
Intermittent fasting reduces liver fat content and CAP scores in patients with MASLD
Intermittent fasting may reduce liver fat in fatty liver disease
This meta-analysis of 8 studies involving 389 subjects found that intermittent fasting significantly reduced liver fat content (MD = -3.01) …
New data suggests intermittent fasting can lower liver fat content and body weight for people with metabolic-related fatty liver disease.
All Gastroenterology Articles
- Higher tolerance of ambiguity correlates with higher perceived benefit in colorectal cancer screening
- FIT positivity and neoplasia detection rates peak in the first round of screening programs
- Terminal ileal intubation provides a 0.28% diagnostic yield for clinically significant pathology in asymptomatic patients
- Pelvic peritoneum closure reduces risk of severe postoperative complications in rectal cancer patients
- Carvedilol and endoscopic variceal ligation show similar efficacy for preventing variceal bleeding in cirrhosis
- Steatotic liver disease prevalence reaches 57.75% in patients with primary hypobetalipoproteinemia
- Semaglutide improves MASH resolution (OR 3.48) and liver fat reduction in MASLD patients
- Statin therapy reduces hepatocellular carcinoma risk and hepatic decompensation by 46% in chronic liver disease
- Multidisciplinary team management reduces mortality risk in patients with hepatobiliary and pancreatic malignancies
- Transanal transection and single-stapled anastomosis reduces anastomotic leakage risk in rectal cancer surgery
- Elevated IGF-I levels correlate with increased risk of colorectal adenoma and colorectal cancer
- Intermittent fasting reduces liver fat content and CAP scores in patients with MASLD
- Multidrug-resistant bacterial infections are prevalent among hospitalized patients with cirrhosis
- Viscoelastic Testing Cuts Transfusions in Cirrhosis Procedures
- Heterozygous SERPINA1 genotypes are associated with increased liver disease risks in Alpha-1 Antitrypsin Deficiency
- Organ transplantation impacts oral microbiome composition and bacteria associated with periodontal inflammation
- Bismuth quadruple and concomitant regimens achieve >85% H. pylori eradication amid rising clarithromycin resistance
- FDA Approves Rezdiffra (resmetirom) for Noncirrhotic NASH with Moderate to Advanced Fibrosis
- Acidic microenvironments reprogram immune cells via pH sensors, driving tissue injury
- Subcutaneous semaglutide more than doubles the likelihood of NASH resolution without fibrosis progression
- New guideline tool curates 51 instruments for theory-driven implementation science assessment
- Intensive CV management reduces cIMT progression in RA patients without hepatic steatosis
- Robotic hepatectomy is safe and offers lower blood loss and shorter hospital stays than open surgery
- Probiotics modestly reduce pain intensity and weekly episodes in children with abdominal pain disorders
- Tissue-resident memory T cells drive disease relapse after biologic and JAK inhibitor discontinuation in atopic dermatitis
- CD4+ T cells and Tim-3 regulate immune responses and cytokine-mediated injury in severe pediatric pneumonia
- MAGIC algorithm and multi-omics approaches facilitate precision management of gastrointestinal acute graft-versus-host disease
- Tryptophan metabolism pathways like IDO and TDO2 influence immune cell function in end-stage liver disease
- Training programs improve healthcare professional confidence and competence in video and text based consultations
- Trained immunity drives mucosal inflammation and recurrence in patients with chronic rhinosinusitis
- Physical exercise may attenuate inflammation and alveolar bone loss in patients with periodontitis
- Google NotebookLM achieves 99.77% critical accuracy and 89.3% workflow time reduction in systematic review data extraction
- Linaclotide combined with polyethylene glycol significantly improves bowel preparation quality in patients with constipation
- Robustly generalizable gut microbiome signatures are identified in patients with colorectal cancer regardless of age
- Antibiotic exposure is associated with an 18.7% higher risk of gastrointestinal cancers
- Gut microbiome biomarkers show AUROC of 0.89 for differentiating colorectal cancer from controls
- Prevention interventions may reduce e-cigarette ever use while cessation-focused efforts likely reduce current adolescent usage
- Microbiota-immune-enteric nervous system interactions provide a framework for understanding functional and slow-transit constipation
- Upadacitinib 15 mg daily improves pruritus and skin sclerosis in a case of refractory lichen sclerosus
- Splenic stiffness measurement shows high sensitivity for varices in children with non-cirrhotic portal hypertension
- Twenty-two factors across five ecological levels are significantly associated with fear of cancer recurrence
- MELD and MELD-Na demonstrate higher specificity than Maddrey discriminant function for alcoholic hepatitis mortality
- Persistent descending mesocolon increases operative time and conversion rates in colorectal cancer surgery
- Endoscopic investigation for iron deficiency anemia reveals 52.0% prevalence of normal upper gastrointestinal findings
- Metabolic and bariatric surgery achieves 70% steatohepatitis remission in patients with MAFLD
- Hepatic vein occlusion with portal vein embolization yields 24.5% greater future liver remnant increase
- JAK inhibitors are associated with higher hepatitis B virus reactivation rates than IL-12/23 or IL-17 inhibitors
- Immune crosstalk between innate and adaptive compartments drives inflammatory mechanisms in MASLD and MASH progression
- Schroth combined with sensory integration training shows greatest Cobb angle reduction in adolescent idiopathic scoliosis
- Plant-derived exosome-like nanoparticles mitigate weight loss and improve colon length in ulcerative colitis models
- The bile acid-gut microbiota-vitamin D axis may influence pathogenesis of biliary atresia
- Axial psoriatic arthritis is associated with significantly lower HLA-B27 positivity than axial spondyloarthritis
- Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
- Anthraquinone laxatives may produce active metabolites via gut microbiota conversion leading to melanosis coli
- Long COVID causes consistent long-term deterioration in physical functioning, vitality, fatigue, and respiratory distress
- Astragalus membranaceus derivatives restore immune tolerance and homeostasis in digestive system diseases
- Laparoscopic partial hepatectomy provides definitive diagnosis and treatment for large atypical hepatic lesions in adolescents
- Lower liver-expressed TRIB1AL levels are associated with reduced liver fat and cardiovascular risk
- Infliximab may offer clinical improvement and wound reduction in non-Crohn's disease related fistulas
- Acupuncture modulates the microbiota-gut-brain axis to remodel microbial structure in patients with irritable bowel syndrome
- Reduced Shannon index indicates lower alpha-diversity in the gut microbiota of patients with primary biliary cholangitis
- Probiotic supplementation may improve salivary buffering and reduce cariogenic bacteria
- Balloon-assisted ESD shows comparable outcomes to conventional ESD for colorectal polyps
- Sympathovagal imbalance correlates with IBS symptom severity and shows subtype specificity
- Narrative review offers a theoretical framework for personalized management of acute upper gastrointestinal bleeding in patients
- Adding linaclotide to PEG did not improve bowel prep quality in high-risk colonoscopy patients undergoing screening procedures
- CYP7A1 and SLC39A9 variants linked to bile acid levels and cholestasis in Chinese women
- Gut-liver axis models evolve from static co-cultures to microfluidic systems, review finds
- Macrophage targeting offers new theoretical approaches for treating gastrointestinal motility disorders and constipation
- Dynamic LSM changes predict liver events in advanced chronic liver disease
- Gut microbiota alterations linked to anxiety and depression in inflammatory bowel disease patients
- Large meta-analysis identifies 30 new genetic loci for ankylosing spondylitis risk
- Oxaliplatin addition to rectal cancer chemoradiation improves tumor regression
- PFIC null genotype linked to 2.79-fold higher odds of liver transplantation
- Hepatologist-led palliative care matches specialist care for cirrhosis and cancer patients
- Fecal DNA testing improved colorectal cancer screening rates compared to immunochemical testing in primary care
- 1 in 6 dromedary camels in Africa carries Rift Valley Fever antibodies
- General obesity, central obesity, and high triglycerides increase risk of precancerous polyps in colorectal cancer surveillance
- Combining Pentraxin-3 and AFP increases sensitivity to 0.92 for hepatocellular carcinoma diagnosis in chronic liver disease
- Endovascular interventions reduce rebleeding risk versus endoscopic cyanoacrylate injection in gastric variceal hemorrhage
- Antimicrobial resistance reaches 33.3% in cirrhosis patients with bacterial infections across global settings
- Prophylactic clipping after colorectal ESD reduces delayed bleeding risk by 74%
- FIPS AUC 0.821 outperforms MELD scores for 90-day mortality prediction in TIPS for ascites
- Blood-based ctDNA tests show low sensitivity for advanced colorectal neoplasia in asymptomatic adults
- Chemoimmunotherapy improves survival in solid tumors regardless of liver metastasis status
- Persistent ymrEMVI and ymrTD on post-neoadjuvant MRI predict inferior disease-free and overall survival in rectal cancer patients
- Higher TyG Index Linked to 4.36-Fold Increased Odds of NAFLD in Large Meta-Analysis
- Microbiome and metabolite markers may enhance colorectal cancer detection and therapeutic guidance strategies
- GLP-1 receptor agonists show potential benefits for metabolic dysfunction-associated steatotic liver disease with acceptable safety
- IL-1β inhibition may alleviate aortic aneurysm immunopathology, review suggests
- Narrative review links gut microbial metabolites to colorectal cancer mechanisms
- FDA Approves Linzess (linaclotide) for IBS-C, CIC, and Pediatric Functional Constipation
- Narrative review links hidradenitis suppurativa to metabolic dysfunction and systemic inflammation
- Bayesian network meta-analysis of drugs for pediatric NAFLD steatosis improvement
- FDA Approves Cholbam (cholic acid) for Bile Acid Synthesis Disorders and Peroxisomal Disorders
- Narrative review explores microbiome-targeting therapies for inflammatory bowel disease patients
- Ursodeoxycholic acid reduces ALT and fibrosis in chronic liver disease patients
- Review of chemopreventive strategies for familial adenomatous polyposis including NSAIDs and other agents
- Review of dietary patterns and probiotics in swine production provides theoretical basis for microbiome interventions
- Pediatric Gut Microbiome Links to Metabolic Dysfunction-Associated Steatotic Liver Disease and Type 2 Diabetes
- Systematic review shows high fatigue and pruritus prevalence in primary biliary cholangitis patients
- Meta-analysis shows curcumin reduces weight but lacks impact on BMI or waist circumference in metabolic fatty liver disease patients
- Systematic Review Explores Ubiquitination in Bacterial Infection and Immune Response
- Review of sphincter-preserving techniques for ultra-low rectal cancer
- Network meta-analysis of phase 2-3 therapies for non-cirrhotic metabolic dysfunction-associated steatohepatitis
- Narrative review explores plant-derived extracellular vesicles for rheumatoid arthritis
- Chinese Version of IBS-SSS Validated for Outcome Assessment in IBS Patients
- Critical review links ADMA levels to endothelial impairment in pregnant women with HIV and preeclampsia in sub-Saharan Africa
- Integrative review links chronic heavy metal exposure to intestinal infection susceptibility in Yunnan
- Meta-analysis of perioperative probiotics shows non-significant reduction in postoperative infections for GI surgery patients
- Systematic review and meta-analysis shows worse liver transplant survival for Black patients compared to White patients
- Review of gut microbiota and colorectal cancer highlights unresolved causality and clinical translation challenges
- Systematic review links gut microbial metabolites to colitis-associated colorectal cancer risk
- High CALLY index predicts improved survival outcomes in colorectal cancer patients compared to low scores
- Metabolic dysfunction-associated steatotic liver disease patients with advanced fibrosis face high hepatocellular carcinoma risk over ten years
- Endoscopic submucosal dissection outperforms precut mucosal resection for colorectal polyp removal
- Surgical resection shows superior survival outcomes compared to radiofrequency ablation for small hepatocellular carcinoma cases
- Bismuth quadruple therapy shows higher H. pylori eradication in pediatric patients with clarithromycin resistance
- Early magnesium sulphate catharsis reduces severe acute pancreatitis and mortality in high-risk patients
- Sequential SBRT, pembrolizumab, and resection in oligometastatic colorectal cancer shows 60% 1-year RFS
- Narrative review discusses NF-kB inhibition for inflammatory bowel diseases and related conditions
- Narrative review explores ferroptosis-immune crosstalk in CNS diseases as therapeutic target
- Single 6 mg erdafitinib dose shows similar pharmacokinetics in mild or moderate hepatic impairment versus healthy controls
- Five ACLF diagnostic models and prognostic scores identified markedly different proportions of patients at risk of 28-day mortality in a cohort study
- SABR shows worse survival in ultracentral pulmonary oligometastases compared to nonultracentral tumors
- SABR in oligometastatic cancer showed median overall survival of 64.6 months in a single-arm phase 2 study
- Tislelizumab plus chemotherapy and radiotherapy yields 89.1% 3-year disease-free survival in pMMR/MSS locally advanced rectal cancer
- Patient Buddy App reduced avoidable readmissions in cirrhosis inpatients compared to standard of care
- Chiglitazar reduces liver fat in MASLD patients with hypertriglyceridemia and insulin resistance
- Text reminders and letters increased FIT completion in overdue colorectal cancer screening patients
- AI-Assisted Colonoscopy Improves Right-Sided Adenoma Detection in Gastroenterology Fellows
- Zibotentan plus dapagliflozin shows no HVPG reduction in compensated cirrhosis
- Avelumab plus cetuximab versus cetuximab alone in metastatic colorectal cancer patients
- Preoperative symbiotic supplementation alters gut microbiota in colorectal cancer patients
- HEV 239 vaccine induces durable humoral and cellular immunity in Bangladeshi women
- TaTME shows lower conversion rates with similar short-term safety compared to LapTME for low rectal cancer
- Systematic review and meta-analysis evaluates ML and DL models for diagnosing MASH and fibrosis
- Meta-analysis of placebo responses in metabolic dysfunction-associated steatohepatitis trials reveals modest natural resolution rates and low progression risk
- Meta-analysis finds Virtual Scale Endoscopy improves colorectal polyp measurement accuracy
- Systematic review and meta-analysis of colorectal cancer screening prevalence in survivors versus general population
- Meta-analysis finds R1 vascular margin acceptable for HCC but not CLM in minimally invasive liver surgery
- Educational programs improve self-care values in ostomized colorectal cancer patients
- Systematic review and meta-analysis assesses SWDS diagnostic accuracy for MASLD liver inflammation grading
- Systematic review finds weak link between atypical antipsychotics and MASLD in youth
- Meta-analysis finds blood biomarkers predict outcomes in anal cancer but need validation
- Systematic review shows high rates of fibrosis and cirrhosis in children with Pi*ZZ alpha-1 antitrypsin deficiency
- PPAR Agonists Reduce Pruritus in PBC: Meta-Analysis of 660 Patients
- Systematic review and meta-analysis of biopsy-guided versus clinically guided withdrawal in autoimmune hepatitis
- Narrative review of traditional Chinese medicine for pancreatitis management
- Retrospective review suggests preoperative data predicts skeletal muscle loss in gastric cancer patients
- Probiotic co-administration with berotralstat improves GI tolerability in HAE patients
- Multi-omics profiling identifies molecular associations in recurrent pregnancy loss
- Narrative review of oxidative stress and antioxidant defense in periodontitis and peri-implantitis
- Meta-analysis shows reduced oral microbial Shannon diversity in Crohn's disease versus controls
- Narrative review examines links between periodontitis and systemic disorders without claiming causation
- Bifidobacterium longum BB536 shows no significant effect on GI symptoms in athletes on high-protein diet
- L-taurine shows no overall fatigue benefit in decompensated cirrhosis but may help non-anemic patients
- Ketotifen shows significant improvements in hepatic steatosis and fibrosis indices compared with vitamin E in a pilot study of NAFLD
- Systematic review finds gut microbiota drugs reduce liver enzymes in MASLD patients compared to placebo
- Cochrane review finds vitamin D may slightly reduce ARI healthcare visits in children
- Oral microbiome profiles differ by periodontitis stage in Korean adults
- Protocol for TEAS adjunct with PEG in elective colonoscopy bowel preparation
- Review of genetic risk haplotypes in Celiac disease across diverse ancestries
- Deep Learning and Explainable AI in Cancer Immunotherapy: A Review of Biomarker Integration
- Systematic review links periodontitis to NAFLD progression and HCC risk
- Vaginal hyaluronic acid associated with epithelial transformation in symptomatic benign cervical ectopy
- Systematic review on neuroimmune mechanisms in preeclampsia
- Observational study links metabolites, microbiota, and brain connectivity in functional dyspepsia
- Preoperative model predicts lateral lymph node metastasis in rectal cancer
- IM-PAC Grading Correlates with Chronic Pancreatitis Severity on CT and MRI
- Integrative review of Epimedium flavonoids in hepatitis and cirrhosis shows preclinical promise but lacks clinical validation
- Meta-analysis of 55 studies assesses HCV prevalence trends across Eastern Mediterranean Region populations
- Scoping review identifies health system components reducing avoidable IBD admissions via access and self-management support
- Narrative review covers IBD, bile acid malabsorption, IBS-D, CRC, obesity, NAFLD, and sepsis-related intestinal injury
- Narrative Review Synthesizes Evidence on Extracellular Vesicles for Premature Ovarian Insufficiency and Testicular Damage
- Narrative review discusses M cell manipulation limitations in inflammatory bowel disease models
- Literature review synthesizes Schisandra chinensis effects on gut microbiota and metabolic pathways across multiple conditions
- Probiotics shorten hospital stay and improve gut recovery after open gastrectomy for gastric cancer
- FMT shifts bile acids faster than vancomycin in recurrent C. difficile infection subgroup
- Observational study maps sex-specific molecular architectures in MASLD using multi-omics profiling
- Narrative review outlines mitochondrial organelle interactions in acute pancreatitis pathogenesis
- Review of secondary analysis on IBS predictors in Bangladeshi students
- Hypertension associated with specific reduction of NK subpopulation in male subjects
- Electroacupuncture at ST36, ST37, and PC6 may shorten recovery times after laparoscopic gastrectomy for gastric cancer
- Cross-sectional data suggest IgG glycans discriminate inflammatory bowel disease from controls
- Review of MASLD without reported population data or specific outcomes
- Narrative review examines TCM herbal extracts and formulas regarding cholestatic liver injury
- Meta-analysis of 7,750 saliva samples validates non-invasive disease prediction models for nasopharyngeal carcinoma, colorectal cancer, and PLHIV
- Gemcitabine exposure associated with higher TP53 and PI3K pathway alterations in pancreatic ductal adenocarcinoma tumors
- Meta-analysis of 9 studies estimates HCV seroprevalence of 3.63% among African refugees and displaced persons
- Scoping review of 60 sources in LMICs identifies barriers to AI adoption and governance gaps
- Fecal microbiota transplantation shows efficacy for recurrent C. difficile infection, IBD, and autism spectrum disorder in children
- Narrative review examines perinatal microbiota influences and evidence gaps in dogs and cats
- Network meta-analysis compares preventive measures for esophageal variceal bleeding in 6510 cirrhosis patients
- Review links oral microbiome dysbiosis to malignant transformation in oral lichen planus
- Narrative review outlines clinical framework for managing primary Sjögren's disease with interstitial lung disease
- Immune checkpoint inhibitor regimens improve survival versus tyrosine kinase inhibitor monotherapies in advanced hepatocellular carcinoma
- Robotic simultaneous resection for synchronous colorectal cancer and liver metastases shows feasibility and safety in a meta-analysis
- Systematic review examines immunological analysis of Blau syndrome pathogenesis to define treatment pathways
- Single-cell sequencing reveals T cell clonal patterns in healthy donors and ulcerative colitis patients