Diabetes & Endocrinology

All Diabetes & Endocrinology Articles

• Low baseline temporal muscle thickness correlates with poorer survival in IDH-wildtype glioblastoma
• Vaginal progesterone increases clinical pregnancy and live birth rates in OS-IUI cycles
• Insulin resistance serves as a sentinel biomarker for progression toward multiple cardiometabolic diseases
• Grape seed extract improves oxidative stress and metabolic parameters in non-communicable diseases
• Balanced electrolyte solutions and 0.9% saline show no difference in pediatric diabetic ketoacidosis outcomes
• Ultrasound imaging serves as a versatile diagnostic tool for multiple diabetes-related complications
• Structured Exercise Improves Muscle Strength and Physical Performance in Seniors with T2DM
• Declining erythritol levels during weight loss correlate with lower 2-year ASCVD risk estimates
• Aerobic exercise programs improve anthropometric outcomes and cardiorespiratory fitness in children with obesity
• Endothelin receptor antagonists reduce albuminuria and kidney events in patients with diabetic kidney disease
• Obesity is associated with significantly worse cognitive performance across six domains in youth
• Comparative Efficacy of Cagrilintide-Semaglutide Doses for Weight Loss in Type 2 Diabetes
• Taijiquan and Baduanjin significantly improve depressive symptoms and glycemic control in Type 2 Diabetes
• Efficacy of Non-Pharmacological Interventions in Managing Metabolic Outcomes for Type 2 Diabetes
• Circulating SFRP4 is significantly higher in type 2 diabetes than in healthy controls
• IGF-1R inhibitors significantly improve proptosis and overall response in patients with thyroid eye disease
• Fatty pancreas disorder is associated with higher odds of fatty liver and diabetes mellitus
• Indole-AhR-Treg axis proposed as context-dependent target for restoring tolerance in type 1 diabetes
• Low vitamin D linked to higher obesity risk, but detection methods alter findings
• Cortisol excess drives skeletal fragility beyond BMD in endogenous Cushing's syndrome
• Anti-inflammatory strategies may stabilize mental functioning and promote autonomic and metabolic homeostasis
• PMOS proposed as developmental disorder shaped by gene-environment and epigenetic mechanisms
• Genome-wide meta-analysis identifies 25 trait-loci associations for cardiometabolic phenotypes in Native Hawaiian and Samoan populations
• Efficacy of GLP-1 Receptor Agonists in Managing MASLD and MASH Clinical Outcomes
• Sodium glucose co-transporter inhibitors show strongest cognitive improvement in Type 2 Diabetes patients
• Adipo-B correlates with beta-cell indices in treatment-naive patients with Type 2 Diabetes
• Prenatal exposure to certain psychotropic medications is associated with increased risk of gestational diabetes
• Metabolic profiles and specific metabolites serve as potential biomarkers for diabetic kidney disease progression
• Telemedicine for gestational diabetes reduces fasting glucose and gestational weight gain in women
• Airway epithelial cell and lung macrophage crosstalk provides a basis for targeting asthma endotypes
• Pembrolizumab-induced hypophysitis can cause arginine vasopressin deficiency unmasked by glucocorticoid therapy
• Retatrutide Shifts Fatty Acid Oxidation and Insulin Resistance Metabolites in Obesity Trials
• Epidemiological studies report a modest bidirectional inverse association between cancer and Alzheimer disease
• Metabolic syndrome prevalence varies significantly based on the specific diagnostic criteria and waist thresholds used
• Environmental and early-life exposures may influence microRNA expression and immune pathways in Type 1 Diabetes
• Resistance training improves eGFR in non-dialysis diabetic kidney disease while mind-body exercise reduces UAE
• Faecal microbiota transplantation did not significantly reduce HOMA-IR in patients with metabolic disorders
• Multidomain intervention did not significantly impact body weight in older adults at risk for dementia
• Hepatocyte senescence and SASP signaling contribute to inflammatory and fibrogenic remodeling in MASLD
• Chinese osteoporosis management guidelines show consensus on diagnosis but vary in specific treatment recommendations
• Diabetic Retinopathy Tied to Higher Dementia Incidence in Pooled Analysis
• Chinese clinical practice guidelines for osteoporosis demonstrate moderate methodological and recommendation quality scores
• SGLT-2is and GLP-1RAs significantly reduce heart failure related composite endpoints in type 2 diabetes
• Acute hyperglycemic phenotypes are associated with increased mortality and mechanical ventilation in COVID-19 patients
• Biomarker-guided therapy using MRI signal and granulation patterns optimizes treatment for acromegaly in Gulf region
• South African Guideline Adapts Canadian Obesity Recommendations for Local Care
• Multiple biomarkers show potential associations with kidney function decline in patients with type 2 diabetes
• Case report: gastric-type cervical adenocarcinoma in situ in Peutz-Jeghers syndrome despite normal screening
• GLP-1 Receptor Agonists in Pregnancy Show No Clear Increase in Most Adverse Outcomes
• AI prescreening tool identifies primary aldosteronism with AUROC 0.709 in hypertension
• Cognitive Behavioral Therapy Improves Sleep Quality and Glycemic Control in Diabetes Patients
• Scoping review finds DR trials often omit diabetes type and use small samples
• Tranexamic acid reduces operative duration and hospital stay in patients undergoing laparoscopic sleeve gastrectomy
• Erector Spinae Plane Block Reduces Opioid Consumption in Bariatric Surgery Patients
• Pregnant women show favorable attitudes toward newborn screening despite limited self-perceived understanding of metabolic diseases
• Adult-derived diagnostic criteria for the developing pelvis are often poorly applicable to pediatric patients
• Histaminergic system dysfunction contributes to arousal maintenance and attention regulation in narcolepsy type 1
• Structured exercise reduces triglycerides and LDL-C in adults with type 2 diabetes
• GLP-1 receptor agonists reduce apnea-hypopnea index by 9.99 events per hour in obstructive sleep apnea
• GART expression correlates with proliferative and purine-metabolic states in ulcerative colitis tissue
• GLP-1 RAs and dual incretin agonists cause delayed gastric emptying and lean mass loss in patients
• INSL3 serves as a robust alternative to testosterone or LH for reflecting Leydig cell status
• Resting energy expenditure does not meaningfully differ between women with and without PMOS
• Structured educational and behavioral interventions reduce fear of hypoglycemia in adults with type 2 diabetes
• Comparative Efficacy and Safety of Endoscopic Sleeve Gastroplasty Versus Laparoscopic Sleeve Gastrectomy
• Urinary incontinence is a prevalent and often undermanaged consequence of endometrial cancer and its treatments
• Microglia are currently candidate contributors rather than established clinical targets in polycystic ovary syndrome
• CagriSema Combination Therapy Demonstrates Superior Weight Reduction Over Semaglutide Monotherapy
• IcoSema reduces HbA1c by 3.32 percentage points compared to 2.44 in type 2 diabetes
• SGLT2 inhibitors improve glycemic control and blood pressure in patients with diabetic chronic kidney disease
• Patients with Graves' disease and Hashimoto's thyroiditis have significantly lower serum 25-hydroxyvitamin D levels
• Mongolian Medicine Compounds Show Immunomodulatory Potential in Sepsis, But Direct Evidence Remains Scarce
• Orforglipron demonstrates an acceptable safety profile in Japanese adults with type 2 diabetes over 52 weeks
• Resistance exercise maintains significant net reduction in T2D risk at 1 year
• Adjunctive placental-derived CAMPs raise 12-week diabetic foot ulcer closure versus standard care
• Near-infrared autofluorescence did not significantly improve cure rates in parathyroidectomy for primary hyperparathyroidism
• MACS affects 26.2% of primary aldosteronism patients and tracks with higher cardiometabolic odds
• Tirzepatide ranks highest for weight and waist reduction among GLP-1 and GLP-1/GIP receptor agonists
• Semaglutide is not associated with significantly increased risks of depression, anxiety, or suicidal ideation
• Digital health interventions reduce HbA1c by 0.37 percentage points in adults with type 2 diabetes
• Impact of Antidiabetic Medications on Survival Outcomes in Patients with Cancer
• Serum folate concentrations do not differ significantly in patients with various thyroid disorders
• Bariatric surgery linked to wider retinal arterioles and narrower venules in obesity
• Impact of GLP-1 Receptor Agonists on Body Composition and Bone Health in Obesity
• Multicomponent, family-focused behavioral interventions yield small HbA1C gains in youth with T1D
• Early mobilization may support regulatory mechanism re-engagement in acute neurocritical patients during intensive care
• Ovarian tissue and oocyte cryopreservation are technically feasible and safe for girls with Turner syndrome
• Sarcopenia prevalence of 27.4% among Indian adults with type 2 diabetes
• CFTR intronic variant c.1210-11T>G associated with pancreatic atrophy and type 3c diabetes
• Exercise therapy for osteoporosis faces significant translational gaps and heterogeneous osteogenic effects across modalities
• Age, smoking, and diabetes are associated with increased risk of postmenopausal osteoporosis
• Concurrent training sequences improve glycemic control and lipid profiles in patients with type 2 diabetes
• Most thyroid hormone system-disrupting chemicals cause T4 decreases without corresponding TSH changes in rodent models
• Intrathyroidal dexamethasone injection improves clinical efficacy and shortens remission time in subacute thyroiditis
• Specific serum biomarkers, including CRP and Vitamin D, show distinct associations with sarcopenia and sarcopenic obesity
• Group prenatal care improves maternal health literacy and reduces gestational diabetes and pre-eclampsia rates
• Ferroptosis serves as a mechanistic link between metabolic stress and bone remodeling dysfunction in osteoporosis
• Weight-neutral, insulin-sensitivity-centered clinical pathways for polyendocrine metabolic ovarian syndrome prioritize metabolic and reproductive outcomes
• Excess weight in children and adolescents is associated with impaired cardiac autonomic modulation
• Limited evidence exists for biomarkers in diagnosing or monitoring chronic inducible urticaria
• HDAC3 acts as a central epigenetic hub for Type 2 Diabetes and its complications
• Resting-state brain functional alterations in diabetic retinopathy relate to cognitive domains and 1,101 genes
• High triglyceride-glucose index increases major adverse cardiocerebrovascular events in patients with CKM syndrome
• Healthcare-related time toxicity impacts women managing gestational diabetes mellitus in outpatient settings
• Digital Diabetes Patient Reminder tool protocol evaluates albuminuria monitoring in 201 patients with Type 2 Diabetes
• Higher CGM-derived time in range is associated with lower odds of diabetic kidney disease
• Scoping review protocol aims to evaluate quality of diabetes health education and digital integration
• Exercise-responsive endocrine-metabolic mediators are predominantly adipokines, cytokines, and myokines in obesity and diabetes research
• Hypothyroidism and Metabolic Syndrome Frequently Coexist and Share Metabolic Abnormalities
• Vitamin D and gut microbiota interact to regulate immunity and improve bioavailability in thyroid disorders
• Subclinical humoral immune dysfunctions may drive gut-liver axis breakdown in pediatric MASLD
• Middle East Consensus Sets 25 Statements for Achondroplasia Care and Access
• Laparoscopic nephron-sparing tumorectomy and CEUS provide effective management for pediatric reninoma and hypertension
• Orforglipron 36 mg achieves greater weight and metabolic reductions than 12 mg in obese adults
• Public LLM web interfaces achieved 100% agreement with consensus risk categories in diabetes cases
• Statin therapy reduces major amputation risk in patients with diabetic foot infection
• Efgartigimod alfa targets FcRn across three neuroimmune conditions
• In-utero GDM exposure is associated with higher offspring BMI and increased risk of obesity
• Specific TCM formulas combined with mecobalamin show varying effects on diabetic peripheral neuropathy outcomes
• Host non-coding RNAs orchestrate antiviral defense and are targeted by viral counter-defense strategies
• Primary aldosteronism is associated with lower serum potassium and higher urinary albumin excretion
• Air pollution exposure is associated with higher odds of general and abdominal obesity in adults
• Risk models for sepsis-associated acute kidney injury demonstrate a pooled C-statistic of 0.817
• Fragmented patient-reported outcome measures currently characterize the clinical landscape of type 3c diabetes
• Antidiabetic drugs and gut microbiota interact to influence treatment efficacy and tolerability in metabolic syndrome
• Butyrate and fecal acetate levels are significantly lower in patients with type 2 diabetes
• Higher Triglyceride-glucose index increases MACE risk in patients undergoing coronary artery bypass grafting
• Subclinical hypothyroidism does not significantly alter FSH, LH, estradiol, or total testosterone in PCOS
• Short-bout accumulated physical activity reduces mean glucose in adults with type 2 diabetes
• Older age, longer diabetes duration, and higher HbA1c levels associate with sarcopenia in type 2 diabetes
• Ecnoglutide improves glycemic control and reduces body weight in adults with type 2 diabetes
• DEKODE platform protocol aims to improve clinical and process outcomes in diabetic ketoacidosis
• Chinese herbal medicines may protect ovarian function through multi-pathway regulation of cellular stress and senescence
• Genetic Association of CDKAL1 rs7754840 Polymorphism with Gestational Diabetes Mellitus Risk
• Diabetes-specific nutritional formulas reduce mean blood glucose by 0.54 mmol/L in patients with hyperglycemia
• The Faster-Fewer-and-Finished approach aims to maximize time-to-first-live birth for women of advanced reproductive age
• A 50 nmol/L cortisol threshold may be too low for identifying hypercortisolism in adrenal incidentalomas
• Recombinant influenza vaccine yields higher A(H1N1) and A(H3N2) titers in adults with severe obesity
• Multicomponent interventions are most effective for managing childhood and adolescent overweight and obesity
• Elevated Visceral Adiposity Index is associated with increased risk of diabetic kidney disease
• CEUS combined with AI or elastography improves diagnostic performance for malignant thyroid nodules
• T1D MAPS polygenic score improves discrimination in non-EUR populations compared to T1D GRS2
• OSA Tied to Poorer Glucose Control in Type 2 Diabetes
• Immune dysregulation serves as a plausible mechanistic link between pre-pregnancy obesity and gestational diabetes
• Surgical excision of submandibular masses successfully normalized PTH levels in patients with recurrent secondary hyperparathyroidism
• Children with Type 1 Diabetes Mellitus show higher DMFT index for permanent teeth
• Hyperuricaemia may impact skeletal health in children and adolescents through indirect evidence and experimental models
• CareAide mHealth application improves medication adherence and quality of life in type 2 diabetes
• Press needle and plum-blossom needle combination significantly lowers pro-inflammatory cytokines in diabetic peripheral neuropathy
• Exercise interventions improve metabolic flux and fatty acid oxidation in Type 2 Diabetes
• Clopidogrel monotherapy reduces bleeding risk to 2.1% versus 3.2% in patients with acute coronary syndromes
• Syndrome-informed Traditional Chinese Medicine improves sleep quality and reduces blood pressure in patients with comorbid hypertension and insomnia
• Functional creams and urea-containing formulations significantly reduce xerosis severity in patients with diabetes
• Evaluating Glycemic Control and Weight Reduction of SGLT2 Inhibitors Versus DPP-4 Inhibitors
• Higher Triglyceride-glucose index is associated with increased risk of diabetic peripheral neuropathy
• Moxibustion Combination Therapies Improve Nerve Conduction and Clinical Scores in Diabetic Neuropathy
• FGFR3 N540S variant exhibits phenotypic heterogeneity between proportionate short stature and hypochondroplasia
• rs741301 polymorphism is associated with reduced susceptibility to diabetic nephropathy in meta-analysis
• Hashimoto's thyroiditis is a risk factor for papillary thyroid cancer with associated improved outcomes
• Financial incentives and web coaching significantly reduce HbA1c in young adults with Type 1 Diabetes
• Vitamin D deficiency associated with higher maternal and cord blood lipid and ketone levels
• Early time-restricted eating and bright light therapy protocol for insulin-independent type 2 diabetes
• Tirzepatide reduces MACE in adults with Type 2 Diabetes and obesity (OR 0.87)
• Weight management interventions significantly reduce BMI and waist circumference in young adults in LMICs
• Diabetes self-care adherence prevalence is 47% among patients with diabetes mellitus in Pakistan
• Dual immune checkpoint inhibitor therapy significantly increases risk of developing Type 1 Diabetes Mellitus
• Low fat-free mass metrics are associated with increased risk of weight-related metabolic complications
• Automated insulin delivery systems improve time in range and reduce distress in older adults with type 1 diabetes
• Zinc supplementation raises plasma zinc and lowers insulin resistance in diabetes
• Continuous glucose monitoring improves glycemic control and reduces complications in gestational diabetes mellitus
• Speckle-tracking-derived 2D LV GLS is significantly impaired in youths with Type 1 Diabetes
• Global meta-analysis establishes pooled incidence and prevalence rates for diabetic foot complications
• Rapid weight regain occurs after discontinuation of semaglutide or tirzepatide
• FDA Approves Zepbound (tirzepatide) for Weight Reduction and Obstructive Sleep Apnea
• School-based diet and activity interventions show modest adiposity gains in African youth
• Tocilizumab serves as first-line therapy for CRS in CAR-T and VST cellular immunotherapies
• Hyperuricemia prevalence reaches 44.50% in adolescents with obesity and correlates with metabolic dysfunction
• AI chatbots provide clinically harmful or contradictory antidiabetic advice in 11% of responses during Ramadan
• Tirzepatide reduces HbA1c and fat mass in patients with Rabson-Mendenhall syndrome
• Antenatal corticosteroids provide substantial neonatal benefits for threatened preterm birth despite uncertain long-term effects
• Surgical resolution of insulinoma may not fully reverse chronic hypoglycemia-induced peripheral neuropathy
• Allo-HSCT after CAR-T yields sustained remission in DLBCL patient with secondary MDS
• Magnesium oxide results in modest, non-significant HbA1c reduction in Type 2 Diabetes
• Combined aerobic-resistance training provides superior metabolic benefits for obese patients with type 2 diabetes
• Phytochemicals modulate miRNA-mediated regulatory networks to influence metabolic reprogramming and cancer-associated signaling
• Tirzepatide shows a mean difference of 4.23% weight loss over semaglutide at 6 months
• Sociodemographic, laboratory, and ultrasonographic factors are associated with malignancy risk in thyroid nodules
• Older patients with Type 1 Diabetes are more likely to be permitted to fast during Ramadan
• Higher dietary spermidine intake associates with improved hepatic function in older adults with metabolic syndrome
• Senolytics like dasatinib and quercetin show promise for improving skeletal parameters in osteoporosis models
• Euonymus alatus may improve glucose metabolism and reduce urinary protein in diabetic nephropathy
• Sarcopenia doubles mortality and amputation risk in diabetic foot patients
• DOACs reduce thrombosis recurrence and major bleeding compared to warfarin in morbidly obese VTE patients
• Graves' disease is associated with lower bone mineral density and higher serum calcium levels
• Survodutide reduces mean body weight by 12.2% or 13.0% in adults with obesity
• Hypoglycemic phytochemicals improve male reproductive dysfunction and reduce oxidative stress in preclinical diabetes models
• Inflammaging and immunosenescence emerge as key mechanistic axes in osteoarthritis pathogenesis
• Therapeutic LH window of 1 to 10 IU/L supports optimal follicular development in IVF patients
• CircRNAs demonstrate high diagnostic accuracy for osteoporosis with an AUC of 0.91
• Over 90% of clinicians prefer antithyroid drugs despite high relapse rates in Graves' disease