Diabetes & Endocrinology

All Diabetes & Endocrinology Articles

• Host non-coding RNAs orchestrate antiviral defense and are targeted by viral counter-defense strategies
• Primary aldosteronism is associated with lower serum potassium and higher urinary albumin excretion
• Air pollution exposure is associated with higher odds of general and abdominal obesity in adults
• Risk models for sepsis-associated acute kidney injury demonstrate a pooled C-statistic of 0.817
• Fragmented patient-reported outcome measures currently characterize the clinical landscape of type 3c diabetes
• Antidiabetic drugs and gut microbiota interact to influence treatment efficacy and tolerability in metabolic syndrome
• Butyrate and fecal acetate levels are significantly lower in patients with type 2 diabetes
• Higher Triglyceride-glucose index increases MACE risk in patients undergoing coronary artery bypass grafting
• Subclinical hypothyroidism does not significantly alter FSH, LH, estradiol, or total testosterone in PCOS
• Short-bout accumulated physical activity reduces mean glucose in adults with type 2 diabetes
• Older age, longer diabetes duration, and higher HbA1c levels associate with sarcopenia in type 2 diabetes
• Ecnoglutide improves glycemic control and reduces body weight in adults with type 2 diabetes
• DEKODE platform protocol aims to improve clinical and process outcomes in diabetic ketoacidosis
• Chinese herbal medicines may protect ovarian function through multi-pathway regulation of cellular stress and senescence
• Genetic Association of CDKAL1 rs7754840 Polymorphism with Gestational Diabetes Mellitus Risk
• Diabetes-specific nutritional formulas reduce mean blood glucose by 0.54 mmol/L in patients with hyperglycemia
• The Faster-Fewer-and-Finished approach aims to maximize time-to-first-live birth for women of advanced reproductive age
• A 50 nmol/L cortisol threshold may be too low for identifying hypercortisolism in adrenal incidentalomas
• Recombinant influenza vaccine yields higher A(H1N1) and A(H3N2) titers in adults with severe obesity
• Multicomponent interventions are most effective for managing childhood and adolescent overweight and obesity
• Elevated Visceral Adiposity Index is associated with increased risk of diabetic kidney disease
• CEUS combined with AI or elastography improves diagnostic performance for malignant thyroid nodules
• T1D MAPS polygenic score improves discrimination in non-EUR populations compared to T1D GRS2
• OSA Tied to Poorer Glucose Control in Type 2 Diabetes
• Immune dysregulation serves as a plausible mechanistic link between pre-pregnancy obesity and gestational diabetes
• Surgical excision of submandibular masses successfully normalized PTH levels in patients with recurrent secondary hyperparathyroidism
• Children with Type 1 Diabetes Mellitus show higher DMFT index for permanent teeth
• Hyperuricaemia may impact skeletal health in children and adolescents through indirect evidence and experimental models
• CareAide mHealth application improves medication adherence and quality of life in type 2 diabetes
• Press needle and plum-blossom needle combination significantly lowers pro-inflammatory cytokines in diabetic peripheral neuropathy
• Exercise interventions improve metabolic flux and fatty acid oxidation in Type 2 Diabetes
• Clopidogrel monotherapy reduces bleeding risk to 2.1% versus 3.2% in patients with acute coronary syndromes
• Syndrome-informed Traditional Chinese Medicine improves sleep quality and reduces blood pressure in patients with comorbid hypertension and insomnia
• Functional creams and urea-containing formulations significantly reduce xerosis severity in patients with diabetes
• Evaluating Glycemic Control and Weight Reduction of SGLT2 Inhibitors Versus DPP-4 Inhibitors
• Higher Triglyceride-glucose index is associated with increased risk of diabetic peripheral neuropathy
• Moxibustion Combination Therapies Improve Nerve Conduction and Clinical Scores in Diabetic Neuropathy
• FGFR3 N540S variant exhibits phenotypic heterogeneity between proportionate short stature and hypochondroplasia
• rs741301 polymorphism is associated with reduced susceptibility to diabetic nephropathy in meta-analysis
• Hashimoto's thyroiditis is a risk factor for papillary thyroid cancer with associated improved outcomes
• Financial incentives and web coaching significantly reduce HbA1c in young adults with Type 1 Diabetes
• Vitamin D deficiency associated with higher maternal and cord blood lipid and ketone levels
• Early time-restricted eating and bright light therapy protocol for insulin-independent type 2 diabetes
• Tirzepatide reduces MACE in adults with Type 2 Diabetes and obesity (OR 0.87)
• Weight management interventions significantly reduce BMI and waist circumference in young adults in LMICs
• Diabetes self-care adherence prevalence is 47% among patients with diabetes mellitus in Pakistan
• Dual immune checkpoint inhibitor therapy significantly increases risk of developing Type 1 Diabetes Mellitus
• Low fat-free mass metrics are associated with increased risk of weight-related metabolic complications
• Automated insulin delivery systems improve time in range and reduce distress in older adults with type 1 diabetes
• Zinc supplementation raises plasma zinc and lowers insulin resistance in diabetes
• Continuous glucose monitoring improves glycemic control and reduces complications in gestational diabetes mellitus
• Speckle-tracking-derived 2D LV GLS is significantly impaired in youths with Type 1 Diabetes
• Global meta-analysis establishes pooled incidence and prevalence rates for diabetic foot complications
• Rapid weight regain occurs after discontinuation of semaglutide or tirzepatide
• FDA Approves Zepbound (tirzepatide) for Weight Reduction and Obstructive Sleep Apnea
• School-based diet and activity interventions show modest adiposity gains in African youth
• Tocilizumab serves as first-line therapy for CRS in CAR-T and VST cellular immunotherapies
• Hyperuricemia prevalence reaches 44.50% in adolescents with obesity and correlates with metabolic dysfunction
• AI chatbots provide clinically harmful or contradictory antidiabetic advice in 11% of responses during Ramadan
• Tirzepatide reduces HbA1c and fat mass in patients with Rabson-Mendenhall syndrome
• Antenatal corticosteroids provide substantial neonatal benefits for threatened preterm birth despite uncertain long-term effects
• Surgical resolution of insulinoma may not fully reverse chronic hypoglycemia-induced peripheral neuropathy
• Allo-HSCT after CAR-T yields sustained remission in DLBCL patient with secondary MDS
• Magnesium oxide results in modest, non-significant HbA1c reduction in Type 2 Diabetes
• Combined aerobic-resistance training provides superior metabolic benefits for obese patients with type 2 diabetes
• Phytochemicals modulate miRNA-mediated regulatory networks to influence metabolic reprogramming and cancer-associated signaling
• Tirzepatide shows a mean difference of 4.23% weight loss over semaglutide at 6 months
• Sociodemographic, laboratory, and ultrasonographic factors are associated with malignancy risk in thyroid nodules
• Older patients with Type 1 Diabetes are more likely to be permitted to fast during Ramadan
• Higher dietary spermidine intake associates with improved hepatic function in older adults with metabolic syndrome
• Senolytics like dasatinib and quercetin show promise for improving skeletal parameters in osteoporosis models
• Euonymus alatus may improve glucose metabolism and reduce urinary protein in diabetic nephropathy
• Sarcopenia doubles mortality and amputation risk in diabetic foot patients
• DOACs reduce thrombosis recurrence and major bleeding compared to warfarin in morbidly obese VTE patients
• Graves' disease is associated with lower bone mineral density and higher serum calcium levels
• Survodutide reduces mean body weight by 12.2% or 13.0% in adults with obesity
• Hypoglycemic phytochemicals improve male reproductive dysfunction and reduce oxidative stress in preclinical diabetes models
• Inflammaging and immunosenescence emerge as key mechanistic axes in osteoarthritis pathogenesis
• Therapeutic LH window of 1 to 10 IU/L supports optimal follicular development in IVF patients
• CircRNAs demonstrate high diagnostic accuracy for osteoporosis with an AUC of 0.91
• Over 90% of clinicians prefer antithyroid drugs despite high relapse rates in Graves' disease
• Higher dietary inflammatory index scores are associated with patients diagnosed with polycystic ovary syndrome
• FDA Approves Kazano (alogliptin and metformin HCl) for Type 2 Diabetes
• Medically tailored groceries reduce HbA1c by 0.40 points in Medicaid-insured adults with type 2 diabetes
• TyG-derived indices like TyG-WC and CTI show stronger cardiovascular risk associations than the TyG index
• Intrauterine PRP or PRGF infusion increases endometrial thickness but clinical pregnancy results remain fragile
• Breakfast Macronutrient Adjustments Improve Glycemic Control in Diabetes
• GLP-1 receptor agonists reduce apnea-hypopnea index by 15.28 events per hour in obstructive sleep apnea
• Meta-analysis Evaluating Cardiovascular Mortality Risk in Patients with Overt and Subclinical Hypothyroidism
• Tirzepatide reduces hypertension risk but increases hypotension risk compared to semaglutide in T2DM and obesity
• Evaluation of Once Weekly Subcutaneous Zenagamtide for Management of Type 2 Diabetes
• Obesity increases colorectal cancer risk while normal weight is associated with lower risk
• FDA Approves Synjardy XR (empagliflozin/metformin HCl ER) for Type 2 Diabetes
• FDA Approves Jentadueto XR (linagliptin/metformin) for Type 2 Diabetes
• FDA Approves Segluromet (ertugliflozin/metformin) for Type 2 Diabetes
• FDA Approves Xigduo XR (dapagliflozin/metformin) for Type 2 Diabetes and Related Indications
• FDA Approves Janumet XR (sitagliptin/metformin) for Type 2 Diabetes
• Poor glycemic control in Type 2 Diabetes is associated with lower FEV1 and FVC volumes
• FDA Approves Invokamet (canagliflozin/metformin) for Type 2 Diabetes
• FDA Approves Invokamet XR (canagliflozin/metformin) for Type 2 Diabetes
• FDA Approves Zituvimet XR (sitagliptin/metformin HCl ER) for Type 2 Diabetes
• FDA Approves Trijardy XR (empagliflozin, linagliptin, metformin HCl) for Type 2 Diabetes
• FDA Approves Janumet (sitagliptin/metformin) for Type 2 Diabetes
• Glucagon-like peptide-1 receptor agonists associated with reduced Parkinson's disease risk in type 2 diabetes
• SGLT2 inhibitors raise hematocrit by 2.29% and hemoglobin by 0.51 g/dL in type 2 diabetes
• Ramped position provides comparable first-pass success to sniffing position for intubating obese patients
• Tirzepatide reduces inflammatory markers and improves metabolic biomarkers in patients with obesity
• Curcumin raises femoral bone density in animal osteoporosis models, meta-analysis finds
• BCAA metabolism modulation may improve insulin sensitivity and alleviate metabolic inflammation in Type 2 Diabetes
• Malnutrition affects 29% of elderly diabetes patients; high risk in 42%
• 4-year lifestyle intervention cuts type 2 diabetes risk by 46% in post-GDM women
• Obese parturients require 1.597 times higher norepinephrine dose to prevent hypotension during cesarean delivery
• Multidisciplinary management strategies improve outcomes for pregnant women with pulmonary arterial hypertension
• Ultrasound-guided thermal ablation achieves 67.0% euthyroidism rate at 12 months in patients with Graves' disease
• FSP1 acts as an endogenous inhibitor of endothelial ferroptosis and vascular leakage in sepsis
• Hashimoto thyroiditis is more prevalent in women with polycystic ovary syndrome (OR 2.69)
• Acupuncture may reduce frequency of nausea and vomiting during pregnancy when combined with medication
• Community health worker-led interventions reduce systolic blood pressure by 5.5 mm Hg
• TCM formulas and monomeric compounds restore macrophage polarization balance in Sjögren's syndrome
• Polypharmacy and insulin therapy significantly increase hypoglycemia odds in adults with type 2 diabetes
• COPD patients have higher odds of diabetes mellitus with an adjusted OR of 1.39
• SGLT2 inhibitors significantly reduce dementia risk in patients with type 2 diabetes
• Genetic liability to autoimmune hypothyroidism does not correlate with endometriosis risk or thyroid autoimmunity
• FDA Approves Yorvipath (palopegteriparatide) for Hypoparathyroidism in Adults
• Metabolic bariatric surgery linked to lower breast cancer risk in women with obesity
• SASI bypass results in mean total weight loss of 35.9 kg after 12 months
• Rivaroxaban matches controls for DVT prevention after bariatric surgery, but bleeding risk rises
• Finerenone reduces UACR by 25% in adults with type 1 diabetes and CKD
• Intraoperative dexamethasone increases maximum perioperative blood glucose by 1.86 mM in patients with diabetes
• Group visits lead to greater weight loss than individual visits for patients with high self-esteem
• 16-week behavioral intervention reduces caloric intake by 461 ± 931 kcal/day and UPF proportion
• Undiagnosed Type 2 Diabetes prevalence of 6.67% among adults in South Asia
• Diabetes mellitus prevalence is 6.4% among people living with HIV in East Africa
• Postpartum dietary interventions improve BMI, waist circumference, weight, HOMA-IR, and HbA1c in women with GDM
• Diabetic retinopathy is associated with a significantly higher risk of all-cause dementia
• Face-to-face DSME produces approximately 1.3% HbA1c reduction at 30 weeks in type 2 diabetes
• Orlistat and semaglutide may improve ovulation and pregnancy rates in women with overweight or obesity
• High-intensity interval training associated with -0.73% HbA1c reduction in adults with type 2 diabetes
• Culturally tailored self-management interventions significantly decrease HbA1c levels in people with type 2 diabetes
• High Intensity Interval Training Improves Cardiometabolic Risk Factors in Pediatric Overweight Populations
• Efficacy and Safety Profile of Subcutaneous Semaglutide for Weight Management in Adults
• GLP-1 RA exposure in early pregnancy not significantly tied to hypertensive disorders
• External oblique intercostal block provides greatest opioid-sparing effect for laparoscopic sleeve gastrectomy patients
• Evaluating Enoxaparin Dosing Strategies for Venous Thromboembolism Prophylaxis in Bariatric Surgery Patients
• Mitochondrial metabolic reprogramming and epigenetic modifications drive bidirectional regulation in renal tubular epithelial cells
• Current molecular and cellular phenotypes do not yet support clinical subtype identification for recurrent pregnancy loss
• TNF inhibitors may be effective for juvenile idiopathic arthritis in patients with DiGeorge syndrome
• mHealth apps reduce HbA1c by 0.39% in type 2 diabetes across 19 RCTs
• Oral-health promotion improves outcomes for adults with type 2 diabetes when guidance is provided
• Prediabetes linked to 2.78-fold higher odds of obstructive sleep apnea in meta-analysis
• OSAS not significantly tied to diabetic retinopathy overall, but risk doubles in Asian subgroups
• Radiomics and deep learning provide promising tools for precise assessment of adrenal masses
• Proposed pathway for systematic MASLD/MASH assessment in type 2 diabetes
• Metabolic surgery review outlines framework for T2DM and obesity management
• Protein acetylation serves as a critical regulatory hub for inflammation and metabolism in atherosclerosis
• SGLT2 inhibitors and GLP-1 receptor agonists show similar MACE reduction in type 2 diabetes
• SGLT2 inhibitors reduce body fat without significant impacts on skeletal muscle mass in type 2 diabetes
• Overweight and obesity prevalence in individuals with Down syndrome reaches 22% across mixed-age cohorts
• Gut microbiota dysbiosis and metabolic pathway abnormalities are associated with pediatric Type 1 Diabetes
• Insulin resistance and hyperinsulinemia drive bidirectional links between biological aging and age-related chronic diseases
• Vitamin D deficiency is prevalent among African patients with Type 2 Diabetes and higher HbA1c
• GLP-1 receptor agonists and tirzepatide provide cardiovascular benefits across multiple clinical scenarios
• Laryngeal obstruction as initial sign of MEN2B in two pediatric cases with RET mutations
• T cell signaling and metabolic rewiring are critical for T cell engager efficacy in solid tumors
• Exercise ameliorates both type 1 and type 2 diabetes through multiple mechanisms
• Exercise snacks significantly reduce postprandial glucose iAUC by 5.69 mmol·h/L in sedentary adults
• SSRIs show significant reduction in depressive symptoms only when used for 6 months or longer
• Oral antioxidants improve clinical pregnancy and live birth rates in IVF patients
• Obesity is associated with lower PASI90, PASI75, and PASI100 responses in patients with psoriasis
• AI-OCT reports reduced false-positive DME referral rates from 69.1% to 24.1%
• Diverse transmission dynamics and national control strategies characterize African swine fever and PRRS in Asia
• Dapagliflozin plus pioglitazone reduces HbA1c by 0.49% and improves liver fat content in T2DM
• Coastal regions show higher thyroid cancer prevalence while inland areas have more goiter and hypothyroidism
• Risk factors for intracranial lesions in males with central precocious puberty include neurological symptoms
• Meta-analysis examining the association between diabetes mellitus and low back pain
• Microbial dysbiosis impairs healing of diabetic foot ulcers through reduced diversity and biofilm formation
• GQD plus metformin significantly reduces FPG and 2hPG in adults with Type 2 Diabetes
• A novel PTHLH nonsense variant is associated with brachydactyly type E and short stature
• Women with Polycystic Ovary Syndrome have 24% prevalence of Gestational Diabetes Mellitus
• Balanced nutrition and specific macronutrient guidelines support performance for table tennis athletes
• Age, male sex, low BMI, and comorbidities like diabetes are significant risk factors for sepsis incidence
• High-intensity interval training reduces body weight and fat mass more than moderate-intensity continuous training
• Maternal type 1 diabetes exposure associated with lower offspring risk of developing the condition
• Automated insulin delivery increases time-in-range by 9.88% in young children with type 1 diabetes
• GnRHa treatment for central precocious puberty is associated with 2.7 cm greater adult height gain
• Deep learning models show high sensitivity for identifying various stages of diabetic retinopathy
• Donor KIR B/X genotype is associated with significantly superior overall survival in allogeneic hematopoietic stem cell transplantation
• Shorter cryopreservation duration associated with higher live birth and clinical pregnancy rates in FET
• TCM formulations significantly reduce TCM syndrome scores and improve response rates in Graves' disease
• Orforglipron Demonstrates Superior Glycaemic Control Over Dapagliflozin in Type 2 Diabetes
• Tirzepatide Efficacy and Safety for Managing Type 2 Diabetes in Chinese Patients
• AI models demonstrate high accuracy in predicting progression from Gestational Diabetes to Type 2 Diabetes
• Adrenergic receptor signaling modulates pulmonary innate immunity and barrier integrity in acute lung injury
• Prediction models demonstrate high accuracy for identifying progression from prediabetes to Type 2 Diabetes Mellitus
• Cagrilintide-semaglutide reduces HbA1c by up to 2.33% in adults with type 2 diabetes
• PCSK9 monoclonal antibodies show promise for renal benefit in diabetic kidney disease
• Ubiquitination modifications by E3 ligases and DUBs form tissue-specific regulatory networks in Type 2 Diabetes
• TSH suppression therapy promotes tumor progression via G-protein signaling pathways in differentiated thyroid cancer
• Oral small-molecule GLP-1RAs reduce body weight by 3.93 and HbA1c by 0.94
• Streptozotocin and high-fat diets are common methods for establishing diabetic neurogenic bladder animal models