Digital health interventions do not significantly improve psoriasis severity or quality of life
Digital health tools do not replace standard psoriasis care
This meta-analysis of 1,195 patients with psoriasis found that digital health interventions were not associated with significant improvement…
New data shows that digital health tools do not improve skin scores or quality of life for people with psoriasis compared to standard care.
Biologic therapy for psoriasis reduces incident psoriatic arthritis risk by 46% compared to non-biologic therapy
Biologic Therapy Linked to Lower Risk of Psoriatic Arthritis
This meta-analysis of 124,138 patients found that biologic therapy is associated with a 46% lower risk of developing psoriatic arthritis com…
Biologic therapies, especially IL-23 and IL-17 inhibitors, are linked to a lower risk of developing psoriatic arthritis in adults with psori…
Transcriptomic analysis identifies 1780 immune-related genes consistently dysregulated in lesional plaque psoriasis skin
New analysis identifies key immune genes and metabolic pathways in plaque psoriasis
This meta-analysis of transcriptomic data from 44 independent studies identifies 1780 immune-related genes consistently dysregulated in lesi…
A large review of skin data helps map out the immune signals and metabolic changes that drive plaque psoriasis.
CDKN3 expression varies across cancer types and lacks a universal role in tumor progression
Exploring the Role of CDKN3 Protein in Various Types of Cancer
This narrative review examines the role of CDKN3 across various malignancies, including lung, renal, and hepatocellular cancers. The authors…
Scientists are looking at how the CDKN3 protein affects different cancers, including lung, skin, and breast cancer, to find better treatment…
Baseline immune architecture provides more informative biomarker potential than single immune-cell markers in bladder cancer
Immune Cell Patterns May Help Predict Bladder Cancer Outcomes
This narrative review examines the tumor immune microenvironment (TIME) in bladder cancer, focusing on how immune cell distribution and func…
Understanding how immune cells behave within a tumor may help doctors better predict how bladder cancer patients will respond to various tre…
Icotrokinra increases likelihood of Investigator's Global Assessment 0 or 1 by risk ratio 7.27
Icotrokinra Shows Promise for Moderate to Severe Plaque Psoriasis
This meta-analysis of icotrokinra for moderate-to-severe plaque psoriasis in adolescents and adults found a risk ratio of 7.27 for Investiga…
A new treatment called icotrokinra shows significant skin clearance and improved scores for adults and teens with moderate to severe plaque …
Lysine crotonylation drives tumor progression and may potentiate immunotherapy response in various solid tumors
New Biological Markers May Help Doctors Target Growth in Several Cancer Types
This narrative review explores the role of lysine crotonylation (Kcr) in cancer biology across multiple solid tumor types. The authors concl…
Scientists are looking at how a specific protein change called crotonylation helps cancer grow and may help improve immunotherapy results.
m6A modification dysregulation drives epithelial barrier disruption and airway remodeling in allergic airway diseases
M6A modification plays a key role in allergic airway diseases
This narrative review explores the role of m6A modification in allergic airway diseases. The authors synthesize how m6A dysregulation contri…
New research highlights how a specific molecular change called m6A modification can drive inflammation and damage in allergic airway disease…
Proactive analgesic planning and dexamethasone may mitigate rebound pain in patients undergoing orthopedic surgery
New strategies may help manage pain after orthopedic surgery
This narrative review examines the impact of regional anesthesia management factors, including dexamethasone and multimodal analgesia, on re…
Patients undergoing orthopedic surgery may experience intense rebound pain after local anesthesia wears off, but new management plans are be…
Non-acid reflux components may contribute to the pathogenesis of reflux pharyngitis through multiple pathways
Non-acid reflux may contribute to symptoms of reflux pharyngitis
This narrative review explores the role of non-acid reflux, including bile acids, pancreatic enzymes, pepsin, and gas reflux, in the pathoge…
New insights suggest that substances like bile acids and enzymes, not just acid, may cause damage in people with reflux pharyngitis.
Relational trust and structural support influence women's disclosure of domestic abuse to healthcare professionals
Key Factors Influence Women Sharing Domestic Abuse with Healthcare Providers
This systematic literature review synthesizes factors influencing women's disclosure of domestic abuse and the preparedness of healthcare pr…
Trust and safety are vital for women sharing domestic abuse, but healthcare systems must also be prepared to respond effectively.
AI decision support in nurse-led teledermoscopy associated with 1.73 odds ratio for malignancy detection
AI tools help nurses identify more skin cancer cases
This multi-site observational study evaluated 1,102,382 lesions from 98,422 patients in a teledermoscopy framework. AI decision support was …
Artificial intelligence helped nurses identify more skin cancer cases and provide more frequent treatment recommendations during skin screen…
All Dermatology Articles
- Digital health interventions do not significantly improve psoriasis severity or quality of life
- Transcriptomic analysis identifies 1780 immune-related genes consistently dysregulated in lesional plaque psoriasis skin
- Biologic therapy for psoriasis reduces incident psoriatic arthritis risk by 46% compared to non-biologic therapy
- CDKN3 expression varies across cancer types and lacks a universal role in tumor progression
- Baseline immune architecture provides more informative biomarker potential than single immune-cell markers in bladder cancer
- Icotrokinra increases likelihood of Investigator's Global Assessment 0 or 1 by risk ratio 7.27
- Lysine crotonylation drives tumor progression and may potentiate immunotherapy response in various solid tumors
- m6A modification dysregulation drives epithelial barrier disruption and airway remodeling in allergic airway diseases
- Proactive analgesic planning and dexamethasone may mitigate rebound pain in patients undergoing orthopedic surgery
- Non-acid reflux components may contribute to the pathogenesis of reflux pharyngitis through multiple pathways
- Relational trust and structural support influence women's disclosure of domestic abuse to healthcare professionals
- AI decision support in nurse-led teledermoscopy associated with 1.73 odds ratio for malignancy detection
- PRAME Immunohistochemistry Enhances Diagnostic Accuracy in Acral Cutaneous Melanoma Cases
- Ixekizumab combined with tirzepatide improves disease activity and weight in patients with Psoriatic Arthritis
- Inflammatory memory mechanisms may drive chronic relapse and offer pathways for disease modification in rosacea
- Dupilumab, Lebrikizumab, Tralokinumab All Beat Placebo in Adolescent Eczema, No Clear Winner
- Comparative Efficacy and Safety of Ustekinumab Biosimilars versus Reference Products in Plaque Psoriasis
- Artificial Intelligence Performance in Dermatoscopic Image Interpretation for Skin Cancer Diagnosis
- Mesenchymal Stem Cells Show Early Promise in Moderate-to-Severe Atopic Dermatitis
- Keratinocytes drive psoriasis inflammation through bidirectional epithelial-immune crosstalk
- IRF4 acts as a context-encoded mediator in immune compartments and skin repair processes
- Telestroke systems are consistently associated with higher thrombolysis utilization in patients with suspected stroke
- Pathogenic IKBKG variant identified in a pediatric patient with ectodermal dysplasia and immunodeficiency
- FDA Approves Kybella (deoxycholic acid) for Submental Fat Reduction in Adults
- FDA Approves Ameluz (aminolevulinic acid) for Actinic Keratoses of the Face and Scalp
- Ustekinumab May Improve Inverse Psoriasis in Single Case Report
- Anti-interferon-gamma autoantibody-associated immunodeficiency may explain severe melioidosis and necrotic skin lesions
- Neural interactions and cellular components in psoriasis may offer new therapeutic targets for treatment
- Macrophage metabolic reprogramming and polarization may offer therapeutic targets for chronic airway inflammatory diseases
- Guselkumab achieves 88.8% IGA 0/1 at week 16 in Chinese patients with plaque psoriasis
- BAT2306 shows comparable efficacy and safety to secukinumab in moderate-to-severe plaque psoriasis
- Older age, higher BMI, and comorbidities are associated with lower clearance rates in psoriasis patients
- Larger tumors, higher mitotic counts, and TERT mutations associate with metastasis in CRTC1::TRIM11 fusion tumors
- Preoperative nutritional management and micronutrient supplementation show mixed results for colorectal cancer patients
- Malnutrition and sarcopenia are associated with poorer treatment tolerance and higher toxicity in head and neck cancer
- Rezpegaldesleukin Demonstrates Significant Efficacy in Moderate to Severe Atopic Dermatitis Patients
- Nanomaterial-based delivery systems offer potential strategies for inducing transplantation tolerance in end-stage organ failure
- Adalimumab significantly improves ACR70 and PASI100 outcomes in patients with psoriatic arthritis
- SMART and ART show comparable success for early childhood caries, meta-analysis finds
- Electric welding linked to persistent nodular acne in 2 workers, improving away from exposure
- MDA and ACR20 Best Discriminate Treatment Response in PsA
- Guselkumab improves ACR20 rates to 58.6% and 62.2% in patients with psoriatic arthritis
- Whole goat milk formula reduces atopic dermatitis incidence in infants with parental history
- Pregnancy-associated melanoma does not independently worsen overall survival when stage is adequately controlled
- IL-17 inhibitors rank highly for clearance of scalp, nail, and palmoplantar psoriasis
- Multidisciplinary determination of resectability incorporates tumor biology and perioperative systemic therapy in stage III NSCLC
- Delgocitinib and difamilast rank highest among nonsteroidal topical therapies for pediatric atopic dermatitis
- Single-cell RNA sequencing identifies post-capillary venules and ADAM12+ fibroblasts as potential keloid targets
- Microbiota-directed therapies for atopic dermatitis currently lack consistent human clinical evidence
- FDA Approves Anzupgo (delgocitinib) for Moderate to Severe Chronic Hand Eczema
- FDA Approves Cibinqo (abrocitinib) for Refractory Moderate-to-Severe Atopic Dermatitis
- Mogamulizumab monotherapy achieves 41.2% overall response rate in patients with cutaneous T-cell lymphomas
- EV-associated proteins and miRNAs provide high diagnostic accuracy for Lichen Planus and Oral Lichen Planus
- Motivation-informed digital reminders do not improve task completion compared to standard wording in melanoma trial
- Long-term Safety Profile of Dupilumab in Adults with Moderate to Severe Atopic Dermatitis
- Upadacitinib 30 mg tops JAK inhibitors for moderate-to-severe atopic dermatitis in network meta-analysis
- IO102-IO103 plus pembrolizumab improves progression-free survival in advanced melanoma patients
- Sentinel lymph node biopsy shows 9% positivity rate in patients with desmoplastic melanoma
- FDA Approves Skyrizi (risankizumab) for Ulcerative Colitis in Adults
- FDA Approves Skyrizi (risankizumab) for Ulcerative Colitis in Adults
- FDA Approves Absorica LD (isotretinoin) for Severe Recalcitrant Nodular Acne
- FDA Approves Absorica (isotretinoin) for Severe Recalcitrant Nodular Acne
- Nemolizumab Q4W improves IGA success maintenance by 11.8% over withdrawal in atopic dermatitis
- SSGJ-608 achieves 92.7% to 95.1% PASI75 response in moderate-to-severe plaque psoriasis
- Operating room nurses describe critical trauma management challenges and teamwork dynamics in a qualitative review
- FDA Approves Tremfya (guselkumab) for Ulcerative Colitis and Crohn's Disease
- Early preterm birth linked to lower atopic dermatitis risk in large meta-analysis
- ALK fusion Spitz neoplasms show distinct morphologic patterns and genomic correlates in meta-analysis
- Mohs micrographic surgery reduces local recurrence by 12% versus superficial radiation therapy in nonmelanoma skin cancer
- Quantitative PDA improves understanding and confidence versus qualitative PDA in dysplastic nevus screening
- High-certainty evidence suggests weight-loss interventions improve psoriasis severity and quality of life in adults
- Switching between adalimumab and biosimilar adalimumab-atto shows similar pharmacokinetics in plaque psoriasis
- Icotrokinra 200 mg daily achieves PASI 75 in 73% of patients at Week 16 versus 11% with placebo in moderate-to-severe plaque psoriasis
- Cadonilimab plus chemotherapy improves objective response rate to 0.62 in solid tumor patients
- Real-world meta-analysis of baricitinib for atopic dermatitis shows variable outcomes
- Secondary analysis of Phase 3 trials shows lebrikizumab improves absolute EASI response in moderate-to-severe atopic dermatitis
- Systematic review and meta-analysis of AI for melanoma risk assessment in pigmented skin lesions
- Narrative review explores gut microbiota links to atopic dermatitis pathogenesis and potential therapeutic strategies
- Review highlights emerging mechanisms for allergic contact dermatitis management
- FDA Approves Wezlana (ustekinumab-ttwe) for Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, and Ulcerative Colitis
- FDA Approves Wezlana (ustekinumab-ttwe) for Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, and Ulcerative Colitis
- Marburg MS case shows treatment challenges and fatal outcome
- FDA Approves Siliq (brodalumab) for Moderate to Severe Plaque Psoriasis
- Review of case report suggests multimodal therapy potential for unresectable intraductal papillary mucinous neoplasms of the bile duct
- Narrative review of treatment strategies for primary central nervous system lymphoma
- Narrative review offers theoretical basis for selecting biologic therapies in psoriasis patients with renal concerns
- Meta-analysis of sirolimus for cutaneous squamous cell carcinoma in kidney transplant recipients
- Psoriatic arthritis linked to interstitial lung disease prevalence
- Targeted therapies for psoriasis and psoriatic arthritis significantly alter lipid profiles across diverse patient populations
- Tralokinumab maintains efficacy in adults with moderate-to-severe atopic dermatitis up to 152 weeks
- Brodalumab Improves Palmoplantar Pustulosis in Japanese Adults in Phase 3 Trial
- 5-Fluorouracil and MAL-PDT vs Surgery for Bowen's Disease: 4-Year Outcomes
- Ixekizumab shows efficacy in children with enthesitis-related and juvenile psoriatic arthritis
- Meta-analysis finds early-stage cutaneous angiosarcoma linked to longer survival
- Rapid review and meta-analysis of psychological distress in adults undergoing Mohs micrographic surgery
- Systematic review shows regional differences in HS comorbidity prevalence across North America, Europe, and Asia
- Systematic review of advancements and challenges in NK cell immunotherapy for malignancies
- Preclinical study shows hydrogel microneedle patches sample microbes and immune cells in humans and mice
- Methodological study evaluates synthetic image framework for melanoma classification accuracy in preprint report
- Imsidolimab shows GPPPGA clearance in generalized pustular psoriasis flare at 4 weeks
- Systematic scoping review shows declining filarial infection prevalence in Latin America from 1946 to 2025
- Surgical excision in dromedary camels yields 83.70% recovery with 16.30% complications across cutaneous and subcutaneous masses
- Genetic burden in PI3K–AKT–mTOR pathway linked to microscopic polyangiitis susceptibility in Chinese cohort
- Stapokibart plus glucocorticoids achieves disease control in elderly bullous pemphigoid patients
- 675-nm Diode Laser as Adjuvant Therapy for Telogen Effluvium: A Retrospective Case Series
- Herring roe oil reduces inflammatory biomarkers in mild-to-moderate psoriasis
- Obinutuzumab-guided regimen achieves high remission in refractory membranous nephropathy patients
- Pilot RCT protocol assesses VR-PAT game versus dark screen for pain and anxiety in pediatric laser therapy
- FDA Approves Cosentyx (secukinumab) for moderate to severe plaque psoriasis in adults and pediatric patients 6 years and older
- FDA Approves Cosentyx (secukinumab) for Moderate to Severe Hidradenitis Suppurativa in Adults and Pediatric Patients
- MONO, ORM1, ORM2, and AGP levels show excellent diagnostic value for psoriasis identification in a retrospective case-control study
- Review suggests automated stool management system may reduce costs and nursing time in ICU fecal incontinence
- Review of cohort data finds AD linked to psoriasis risk and biologics associated with lower risk
- FDA Approves Stelara (ustekinumab) for moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis
- FDA Approves Stelara (ustekinumab) for moderate to severe plaque psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis
- Review of chronic skin ulcers in Burkina Faso highlights Buruli ulcer prevalence in pediatric patients
- FDA Approves Abreva () for cold sores/fever blisters on the face or lips to shorten healing time and duration of symptoms
- Guselkumab Phase III trials validate 3VAS and 4VAS measures for psoriatic arthritis disease activity assessment
- Systematic review of public health interventions to curb respiratory infections at sporting mass gatherings
- Machine learning and deep learning applications in inguinal hernia care show promise for risk prediction and training
- Atopic constitution associated with severe Mycoplasma pneumoniae pneumonia in children
- Retrospective study links systemic BP control to better visual outcomes with conbercept for RVO-related macular edema
- Occupational noise exposure linked to cognitive decline in cross-sectional study of 170 workers
- Retrospective pediatric NTM study finds cervical lymphadenitis predominant, diagnostic delays common
- Phase 2 trial finds topical STS01 1% improves SALT scores in patchy alopecia areata
- Pivekimab sunirine shows activity in frontline and relapsed Blastic plasmacytoid dendritic cell neoplasm
- Network meta-analysis finds biologics superior to placebo for pediatric plaque psoriasis
- Outpatient IV sedation for dental care in special needs patients shows 3.3% minor complication rate
- Narrative review suggests endovascular treatment may be feasible and safe for posterior epistaxis
- Centralized hair loss measurement showed better agreement and 50% lower error margins than local rating in mild-to-moderate Alopecia Areata
- AI pipeline shows substantial agreement with dermatologists for grading atopic dermatitis erythema severity
- Meta-analysis compares HAQ-DI, SF36-PF, and SF36-PCS for physical function in psoriatic arthritis trials
- Early proactive TCS for infant AD linked to lower food allergy rates at age 3
- PD-L1 expression shows subtype-specific prognostic value in skin neoplasms, meta-analysis finds
- Bimekizumab maintains complete skin clearance in 73% of psoriasis patients at 4 years
- Retrospective analysis identifies molecular correlates of benefit with encorafenib-based therapy in BRAF-mutant melanoma
- Phase 2 trial: Topical STS01 shows dose-related hair regrowth in mild-moderate alopecia areata
- Meta-analysis finds oral JAK inhibitors increase HDL and LDL cholesterol levels in patients from RCTs
- Smartphone-based wound measurement shows excellent agreement with planimetry in single-center study
- Hair follicle-derived epithelial sheet transplantation shows repigmentation in stable vitiligo patients
- CDC recommends approaches to maintain tuberculin skin testing during expected Aplisol shortage
- Simulation study finds HEPA air cleaners and masking reduce exposure to simulated SARS-CoV-2 aerosols
- Report compares motor vehicle crash death rates across 29 high-income countries
- Case report: Initial positive measles IgM tests in two Samoan children were false positives
- Traffic-related death rates compared between US and 27 other high-income countries
- Report describes emergency department visits for traffic-related pedestrian injuries in the US
- Outbreak of Purpureocillium lilacinum fungal skin infections reported at Washington dermatology clinic
- Chinese APS-1 patients show recurrent AIRE gene deletion, male predominance, and low classic triad incidence
- Review analyzes PANoptosis mechanisms and potential treatments for ischemia-reperfusion injury
- Oral ME3183 shows higher PASI-75 response rates than placebo in moderate to severe plaque psoriasis trial
- Network meta-analysis ranks upadacitinib highest for efficacy in moderate-to-severe atopic dermatitis
- Placebo effect observed in double-blinded food challenges for dogs with atopic dermatitis
- Imiquimod costs substantially less than radiotherapy for lentigo maligna in Australian analysis
- Arthroscopy-assisted curettage and bone grafting for proximal femur giant cell tumor in a 25-year-old man
- Guselkumab Shows Improvement in Inverse Psoriasis in Single Case Report
- Nomogram predicts occupational contact dermatitis risk in Chinese nurses with excellent discrimination
- PFAS mixture exposure shows positive association with serum total IgE levels in Korean adults
- Topical PDE4 inhibitors show efficacy in pediatric atopic dermatitis meta-analysis
- Phase 2 study of lifileucel TIL therapy in 220 patients with metastatic melanoma
- Phase 3 trial of bimekizumab versus placebo in 435 adults with moderate to severe plaque psoriasis
- Phase 3 trial of low-dose IL-2 versus placebo for severe alopecia areata completed in 44 patients
- Phase II trial compares IMCgp100 vs investigator choice in advanced uveal melanoma
- Phase 2a study of bimekizumab in chronic plaque psoriasis reports pharmacokinetics and PASI change at Week 28
- Phase 3 Study Evaluates Barzolvolimab for Chronic Spontaneous Urticaria
- Sliding Cupping Therapy Matches NBUVB in Psoriasis Severity Reduction at 8 Weeks