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Pediatrics

511 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Social and emotional skills training shows non-significant reductions in loneliness among children and adolescents
Pediatrics Meta-analysis
Social and emotional skills training shows non-significant reductions in loneliness among children and adolescents Social and Emotional Training Shows Promise for Youth Loneliness
This meta-analysis of 18 studies evaluated interventions targeting loneliness, including social and emotional skills training, in youth aged…
New research looks at how social and emotional skills training can help reduce feelings of loneliness in children and teenagers.
Prenatal 6:2 Cl-PFESA exposure is associated with lower birth weight in infants across specific sub-analyses
Pediatrics Meta-analysis
Prenatal 6:2 Cl-PFESA exposure is associated with lower birth weight in infants across specific sub-analyses Chemical in everyday products linked to lower birth weight
This meta-analysis of 12 studies examined the association between prenatal 6:2 Cl-PFESA exposure and infant birth weight. While no overall s…
A common chemical may reduce newborn weight by up to 20 grams. New analysis of 12 studies raises concerns for fetal health.
Early enteral feeding reduces hospital stay by 3.53 days and speeds time to full feeds
Pediatrics Meta-analysis
Early enteral feeding reduces hospital stay by 3.53 days and speeds time to full feeds Early feeding helps children recover faster after intestinal surgery
This meta-analysis of randomized controlled trials involving 704 pediatric patients found that early enteral feeding (within 48 hours) signi…
Starting tube feedings within 48 hours of intestinal surgery can help children reach full feeds faster and spend less time in the hospital.
Ambulatory hypertension in pediatric chronic kidney disease patients increases risk of left ventricular hypertrophy
Pediatrics Meta-analysis
Ambulatory hypertension in pediatric chronic kidney disease patients increases risk of left ventricular hypertrophy High Blood Pressure Linked to Heart Changes in Children
This meta-analysis of 51 studies involving 6509 children with chronic kidney disease found that ambulatory hypertension is associated with i…
New data shows a strong link between high blood pressure and heart muscle thickening in children with chronic kidney disease.
Congenital cytomegalovirus is associated with a 10-fold increased risk of vestibular changes in children
Pediatrics Meta-analysis
Congenital cytomegalovirus is associated with a 10-fold increased risk of vestibular changes in children Children with congenital cytomegalovirus face higher risk of balance issues
This meta-analysis of 8 observational studies examined the association between congenital cytomegalovirus (cCMV) and vestibular outcomes in …
Children born with a specific virus may face much higher risks for inner ear and balance problems, though more research is needed to confirm…
NICU noise levels frequently exceed recommended limits and primarily originate from alarms and respiratory devices
Pediatrics Meta-analysis
NICU noise levels frequently exceed recommended limits and primarily originate from alarms and respiratory devices NICU noise levels often exceed safety limits for preterm infants
This systematic review of 113 studies identifies alarm systems and respiratory support as primary sources of high-level noise in NICUs. Whil…
Most neonatal intensive care units have noise levels much higher than recommended, especially from alarms and breathing equipment.
MIRAGE syndrome in a neonate: SAMD9 mutation links 46,XY DSD with multisystem features
Pediatrics Sys. Review
MIRAGE syndrome in a neonate: SAMD9 mutation links 46,XY DSD with multisystem features Rare syndrome identified in newborn with female genitalia and XY chromosomes
This case report with literature review describes a male neonate with 46,XY karyotype and female external genitalia who was diagnosed with M…
A newborn with female genitals but male chromosomes was found to have MIRAGE syndrome, a rare genetic disorder linked to SAMD9 mutations.
Sabin-strain inactivated poliovirus vaccine provides immunogenicity comparable to Salk-strain inactivated poliovirus vaccine
Pediatrics Meta-analysis
Sabin-strain inactivated poliovirus vaccine provides immunogenicity comparable to Salk-strain inactivated poliovirus vaccine Sabin Strain Vaccine Shows Comparable Protection Against Polio
This systematic review and meta-analysis of 4646 infants found that Sabin-strain inactivated poliovirus vaccine (sIPV) yields seroconversion…
New analysis shows the Sabin-strain vaccine provides similar protection against polio as the Salk-strain for infants, supporting global heal…
Reduced-dose craniospinal radiation and smaller volume boost for medulloblastoma patients
Pediatrics Phase III
Reduced-dose craniospinal radiation and smaller volume boost for medulloblastoma patients Trial Shows Reduced Radiation May Help Children With Medulloblastoma
This randomized phase 3 trial evaluated reduced-dose craniospinal radiation (18.00 Gy) and a smaller volume boost in children aged 3 to 7 wi…
A large clinical trial looked at whether reducing radiation doses for children with medulloblastoma can maintain safety and effectiveness.
Multimodal therapy and targeted inhibitors show modest activity for pediatric malignant rhabdoid tumor of the kidney
Pediatrics Sys. Review
Multimodal therapy and targeted inhibitors show modest activity for pediatric malignant rhabdoid tumor of the kidney New Targeted Therapies Show Potential for Rare Kidney Tumors
This mini review examines multimodal therapies, EZH2 inhibition, and CDK4/6 blockade for pediatric patients with malignant rhabdoid tumor of…
Targeted treatments like EZH2 and CDK4/6 inhibitors may offer new options for children with a rare type of kidney cancer.
Aprotinin and tranexamic acid show varying efficacy for hemostasis in neonatal cardiac surgery
Pediatrics Meta-analysis
Aprotinin and tranexamic acid show varying efficacy for hemostasis in neonatal cardiac surgery Trial Shows Aprotinin May Reduce Blood Loss in Infant Heart Surgery
This network meta-analysis of 27 studies involving 4,556 patients evaluated various hemostatic strategies in neonatal and infant cardiac sur…
A large review of 4,556 patients suggests aprotinin may be more effective than other treatments for managing blood loss during infant heart …
Deferred single-stage surgical intervention is a safe option for repairing omphalocele with congenital stoma
Pediatrics Sys. Review
Deferred single-stage surgical intervention is a safe option for repairing omphalocele with congenital stoma Surgical Repair Options for Omphalocele with Congenital Stoma
This scoping review and case report examine the management of neonates with omphalocele associated with a congenital stoma. The authors sugg…
A new look at surgical options shows that some infants with omphalocele and a congenital stoma may benefit from specific staged repair metho…

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