Mini-PCNL and standard PCNL show comparable stone-free rates in pediatric patients with nephrolithiasis
Mini-PCNL and Standard PCNL Show Similar Success for Kidney Stones
This meta-analysis of 490 pediatric patients compared mini-PCNL to standard PCNL for nephrolithiasis. The analysis found comparable stone-fr…
Mini-PCNL and standard PCNL procedures show similar success rates for removing kidney stones in children, despite differences in surgery tim…
Parental Perspectives and Acceptance Rates Regarding Off-Label Medication Use in Pediatric Patients
Parents Show Mixed Views on Off-Label Drug Use for Children
A meta-analysis reveals significant variation in parental awareness and acceptance of off-label drug use, highlighting a need for trust-cent…
Parents show varying levels of awareness and acceptance when it comes to using off-label medications for their children's health.
Family-centered nursing improves asthma control and lung function in preschool children
Family-centered nursing improves asthma control for preschool children
This meta-analysis of randomized controlled trials found that family-centered nursing interventions significantly improved asthma control sc…
Family-centered nursing helps preschool children with asthma breathe better, improves their quality of life, and reduces the need for hospit…
High-intensity interval training does not reduce body weight or BMI more than continuous aerobic training
High Intensity Training Shows No Advantage Over Aerobic Exercise
This meta-analysis of 14 trials involving youth with overweight or obesity found no statistically significant differences between high-inten…
High-intensity interval training does not appear to reduce weight or body fat more than standard aerobic exercise for youth with overweight …
Dexmedetomidine nasal spray vs chloral hydrate for pediatric sedation: protocol only, no results yet
New plan to test nasal spray for calming children during exams
This is a protocol for a single-center randomized controlled trial of 248 children aged 2 to 6 years with ASA physical status I/II requiring…
A new study plan aims to see if a nasal spray can safely calm children during outpatient medical exams instead of using oral syrup.
Prenatal Particulate Matter Exposure Linked to 34% Higher Autism Risk in Meta-Analysis
Prenatal Particulate Matter Exposure Linked to Autism Risk
This meta-analysis of 16 case-control studies found that prenatal particulate matter exposure was associated with a 34% increased risk of au…
Research shows that exposure to particulate matter during the third trimester of pregnancy is linked to a higher risk of autism in children.
Impact of In Utero Electronic Nicotine Delivery System Exposure on Neonatal Birth Outcomes
Vaping during pregnancy may increase risks of preterm birth
Evidence suggests that in utero exposure to electronic nicotine delivery systems significantly increases the odds of preterm birth.
New data suggests that babies exposed to vaping products in the womb face higher risks of being born too early and having lower birth weight…
THA and TKA in patients under 25 improve function and quality of life
Joint Replacement Surgery Improves Quality of Life for Young Patients
This meta-analysis of 3317 patients and 5,632 joints evaluates THA and TKA for end-stage joint disease in patients under 25. The analysis fo…
Younger patients with end-stage joint disease can see significant improvements in function and quality of life after hip or knee replacement…
Optimized weight-based dosing for ethambutol addresses sub-therapeutic exposure in children with tuberculosis
Optimized Ethambutol Dosing May Improve Treatment for Children with Tuberculosis
This meta-analysis evaluates ethambutol pharmacokinetics and dose optimization in children with tuberculosis. The analysis found that curren…
Current dosing for the tuberculosis drug Ethambutol may be too low for some children, potentially affecting how well the medicine works.
OpenNotes may improve treatment adherence and shared decision-making in dental practice based on medical analogies
OpenNotes Could Improve Patient Engagement in Dental Care
This narrative review explores the potential of OpenNotes as a patient engagement strategy in dentistry. The authors suggest that sharing cl…
Sharing clinical notes with patients may improve treatment adherence and shared decision-making, though more dental-specific research is nee…
Functional Status Scale identifies mild to moderate impairment in children on ECMO support
New data shows functional outcomes for children on ECMO machines
This scoping review of 25 publications examines the Functional Status Scale (FSS) to assess outcomes in children on ECMO. The review finds t…
Children surviving on ECMO machines often face mild to moderate physical challenges, particularly with breathing and eating, after they leav…
Hydrocortisone Linked to Favorable Course in First Triple A Syndrome Case in French Guiana
Rare Triple A Syndrome Diagnosed in French Guiana Boy
This is a single case report of a 5-year-old boy in French Guiana with Triple A syndrome, confirmed by a homozygous pathogenic AAAS variant,…
A 5-year-old boy in French Guiana is the first confirmed case of Triple A syndrome there, with a favorable response to hydrocortisone.
All Pediatrics Articles
- Parental Perspectives and Acceptance Rates Regarding Off-Label Medication Use in Pediatric Patients
- Mini-PCNL and standard PCNL show comparable stone-free rates in pediatric patients with nephrolithiasis
- Family-centered nursing improves asthma control and lung function in preschool children
- High-intensity interval training does not reduce body weight or BMI more than continuous aerobic training
- Dexmedetomidine nasal spray vs chloral hydrate for pediatric sedation: protocol only, no results yet
- Impact of In Utero Electronic Nicotine Delivery System Exposure on Neonatal Birth Outcomes
- Prenatal Particulate Matter Exposure Linked to 34% Higher Autism Risk in Meta-Analysis
- Optimized weight-based dosing for ethambutol addresses sub-therapeutic exposure in children with tuberculosis
- THA and TKA in patients under 25 improve function and quality of life
- OpenNotes may improve treatment adherence and shared decision-making in dental practice based on medical analogies
- Functional Status Scale identifies mild to moderate impairment in children on ECMO support
- Hydrocortisone Linked to Favorable Course in First Triple A Syndrome Case in French Guiana
- Hirschsprung disease research shifts toward guideline-driven care and HAEC prevention
- Integrated Intervention Improves Weight and Reduces Anemia in Term SGA Infants
- Meta Analysis Evaluating Efficacy of 0.01% Atropine for Myopic Progression in Children
- Prenatal lead exposure is associated with a modest reduction in standardized IQ scores
- Robot-assisted gait training and resistance training improve motor function in children with cerebral palsy
- Polymyxins in resistant Gram-negative infections: 22% all-cause mortality, 10% nephrotoxicity
- AKI Affects 30.7% of Pediatric Liver Transplant Recipients in Pooled Analysis
- Decision rule based on clinical symptoms and procalcitonin reduces antibiotic use in children with fever
- Exercise interventions significantly improve overall, gross, and fine motor skills in children with autism
- Radiopaque markers, scintigraphy, and manometry remain the most widely used colonic motility assessment modalities
- Exercise interventions improve bone mineral density, cardiorespiratory endurance, and quality of life in children with acute leukemia
- PCV10 vs PCV13 in Infants: Serotype-Specific Seroinfection Risk Differences
- Busulfan-based conditioning favors survival in AML while TBI yields better outcomes in ALL
- PLEX and corticosteroids show highest clinical response rates in chronic inflammatory demyelinating polyradiculoneuropathy
- Adjunctive corticosteroids do not significantly reduce coronary artery abnormalities in patients with Kawasaki disease
- Multifactorial risk factors and preventive strategies for children with precocious puberty
- PDA closure rates decrease significantly after second and third courses of cyclooxygenase inhibitors in preterm infants
- Intraoperative traction shows favorable but imprecise association with correction rates in adolescent idiopathic scoliosis
- PMSA-2025 screening tool achieves high content validity for identifying mild malnutrition in children
- Immediate skin-to-skin contact for 2 hours improves infant and maternal outcomes in neonatal care
- Prophylactic oral antibiotics do not reduce cholangitis incidence in patients with biliary atresia
- Off-label growth hormone yields catch-up growth in Takenouchi-Kosaki syndrome case
- Self-weaning shows no significant difference from dose-adjusted weaning in caffeine duration for apnea of prematurity
- Synchronized nasal intermittent positive pressure ventilation reduces extubation failure in preterm infants with respiratory distress
- Schroth and bracing show a trend toward better short-term Cobb angle control in adolescent idiopathic scoliosis
- Acupuncture and moxibustion improve adenoid to nasopharynx ratio in children with adenoid hypertrophy
- Smoking Cessation Aids Parents of Chronically Ill Children
- Small-donor single-kidney transplants show lower 1-year graft survival and higher acute rejection rates
- DeepSeek-R1 outperforms ChatGPT-4o in Chinese DDH caregiver guidance accuracy
- Early childhood caries results from disrupted developmental ecology of the infant oral ecosystem
- Intravenous Esketamine Reduces Oculocardiac Reflex Incidence During Pediatric Strabismus Surgery
- Evaluating Text Message Video Interventions for Improving Infant Sleep Safety Practices
- Teacher-administered vision screening shows 93.6% specificity and 76.8% sensitivity for refractive errors in children
- Mikhuna intervention increases subcortical fetal brain structure growth in pregnant women in Ecuador
- Bracing and physiotherapeutic scoliosis-specific exercises are confirmed effective for scoliosis in children and adolescents
- Higher paternal sensitivity predicts higher cognitive scores in children born preterm and term
- 211LA care coordination does not improve developmental outcomes in children aged 21 to 42 months
- Evaluating the Association of Childhood Sexual Abuse and Adolescent Anorexia Nervosa
- Congenital hepatic fibrosis care lacks targeted therapies; management focuses on portal hypertension complications
- A de novo RYR1 variant may be pathogenic in a newborn with severe hypotonia and respiratory failure
- Capsular bag fixation is preferred over ciliary sulcus fixation for pediatric cataract surgery
- mNGS achieves 85.83% pathogen detection rate in children with severe pneumonia compared to 49.97% for conventional methods
- Ball sports significantly improve core symptoms in children with autism, meta-analysis finds
- Individuals with autism spectrum disorder exhibit significantly poorer olfactory performance compared to non-autistic peers
- FDA Approves Hemangeol (propranolol) for Proliferating Infantile Hemangioma
- Exercise improves executive function in children with autism, meta-analysis finds
- Convergent hypoactivation in the left fusiform gyrus and inferior parietal lobule characterizes dyslexia across writing systems
- ABO-Incompatible Liver Transplant Outcomes Comparable in Children
- High disease activity in paediatric SLE is associated with increased risk of multisystem involvement
- Honey significantly reduces cough impact on child sleep in pediatric patients with acute cough
- Children with developmental coordination disorder consistently demonstrate lower motor skills across all domains
- Zirconia crowns show higher retention and lower failure rates than composite strip crowns
- Early exclusive enteral feeding does not increase necrotizing enterocolitis risk in preterm infants
- Lower diaphragm thickening fraction linked to extubation failure in ventilated neonates
- Malaria presence at vaccination reduces HPV16 and HPV18 antibody levels in two-dose arms
- Brain-computer interfaces in elderly care raise six core ethical challenges
- Maternal cocaine exposure is associated with neonatal deaths but lacks established lethal concentration thresholds
- AI-assisted telescreening and mobile units may provide cost-effective screening for retinopathy of prematurity
- Smokerface-Poster campaign shows lower increase in smoking prevalence with NNT of 93
- EV-A71 vaccine provides over 98% efficacy against EV-A71-associated hand, foot, and mouth disease in children
- Multisensory interventions improve neurodevelopmental outcomes in preterm infants compared to standard or unisensory care
- Systematic review protocol planned to evaluate iron supplementation on neurodevelopmental outcomes in infants and pregnant women
- Evaluating Mefloquine Dosage Effects and Tolerability in Artesunate-Mefloquine Regimens for Malaria
- Tapering enteroplasty shows no significant difference in postoperative outcomes compared to primary anastomosis
- Endoscopic vacuum-assisted closure achieves 99.81% success rate in pediatric esophageal leaks and perforations
- Active breaks during classroom instruction improve attention and inhibitory control in children and adolescents
- TORCH seroprevalence 32.5% in Malaysia; CMV highest, screening urged
- Dexmedetomidine plus esketamine may reduce postoperative delirium and injury
- Low-dose oral dexamethasone is comparable to high-dose dexamethasone for managing children with croup
- Preoperative evaluation of pediatric neck masses should include ultrasound and thyroid function testing
- Mitochondrial dysfunction and post-translational modifications drive progression of radiation-induced heart disease
- Probiotic supplementation reduces neonatal jaundice and respiratory distress syndrome risk in preterm infants
- Artificial intelligence, robotic-assisted surgery, and 5G-enabled telesurgery are advancing precision in thoracic surgical procedures
- Loneliness as a transdiagnostic diagnostic modifier may improve risk stratification and treatment planning in psychiatric practice
- Internet-based home care education improves medication adherence and caregiver self-efficacy in pediatric pulmonary hypertension
- Cuba maintains a solid normative basis for pediatric palliative care despite identified gaps in training
- Home-based physical exercise improves aerobic capacity in children with chronic diseases like Cerebral Palsy
- No regional anesthesia technique shows statistically significant superiority for pediatric hypospadias repair pain scores
- Robotic-assisted Kasai portoenterostomy shows comparable jaundice clearance and liver survival to open or laparoscopic techniques
- RIT1 p.Thr83Pro variant is associated with severe neonatal outcomes in Noonan syndrome cases
- Azithromycin does not raise macrolide-resistant gene prevalence in preterm infants
- Non-intubated VATS shows lower hazard for OS and DFS/RFS compared with intubated VATS
- Air pollution exposure tied to lower thyroid hormone levels in pregnant women and neonates
- Child and adolescent peer adversity is associated with poorer adult interpersonal functioning in meta-analysis
- Sinovac serum-free rabies vaccine meets non-inferiority criteria for seroconversion rates and geometric mean concentrations
- Minimally invasive tooth extraction techniques and adjunctive socket preservation improve alveolar bone and esthetic outcomes
- Incomplete immunization prevalence of 26% among children under five years in India
- Seasonal influenza vaccine effectiveness increased against A(H3N2) and B strains in post-pandemic period
- Children with cochlear implants report lower quality of life in social and school domains
- LUS aeration score shows high diagnostic accuracy predicting extubation failure in mechanically ventilated neonates
- Oral amoxicillin or amoxicillin-clavulanate is non-inferior to intravenous treatment for severe CAP in children
- Aerobic exercise improves sleep outcomes in children and adolescents, but effect size uncertain
- Nursing Care Improves Pediatric Pneumonia Outcomes
- Probiotics improve hematologic parameters in Chinese children with iron deficiency anemia
- Moments that Matter parenting programme improves caregiving but shows no effect on child development
- HFNC shows significantly lower adverse event rates than CPAP in children with bronchiolitis
- Chronic dermatologic conditions significantly impact psychological distress and health-related quality of life in pediatric patients
- Telemedicine consultations do not differ from telephone consultations in quality of care for seriously ill children
- NICU-FACCE survey shows high reliability and validity for family-centered care
- Awake laryngeal mask removal reduces airway obstruction risk compared to deep laryngeal mask removal
- Combined nasopharyngeal and oral suction reduces respiratory adverse events in children with upper respiratory infections
- Robot-assisted ureteric reimplantation provides comparable success to open surgery for pediatric vesicoureteral reflux
- Eye-tracking gaze measures show 0.845 AUC for autism diagnosis in children
- Surgical exploration of the brachial artery increases immediate pulse return in paediatric supracondylar humerus fractures
- Motor competence is associated with improved mental health outcomes in youth aged 5 to 19
- Primary lip repair reduces anterior cleft width by 6.217 mm and curvature angle by 14.66 degrees
- Allogeneic hematopoietic stem cell transplantation achieves transfusion independence in children with KLF1 mutation-associated CDA IV
- Children with obstructive sleep-disordered breathing have significantly smaller upper airway cross-sectional areas
- Sepsis, not breastfeeding, and no KMC significantly increase mortality risk in low birth weight neonates
- Prebiotics, probiotics, and synbiotics do not provide clinically important benefits on hemoglobin or ferritin in children
- Abdominal ultrasound detects portal venous gas more frequently than conventional radiography in neonatal necrotizing enterocolitis
- PA-VLLF ChatGPT architecture achieves 86.36% accuracy in pediatric pain assessment comparable to senior experts
- New 15-item scale reliably measures parental agency in Chinese NICUs
- Plyometric Training Boosts Jump, Sprint, Agility in Teens
- 28% recurrence rate after antiseizure medication withdrawal in children with epilepsy
- Metagenomic sequencing identifies Rickettsia felis encephalitis in a child who fully recovered
- Compound heterozygous mutations in NPHP4 gene identified in a patient with nephronophthisis and proteinuria
- Echocardiographic Measures Predict Bronchopulmonary Dysplasia in Preterm Infants
- VR-based exercise improves executive function in children with autism, meta-analysis finds
- Physical abuse prevalence is 61.7% among children and youth experiencing homelessness
- Recipe 4 Success improves parenting and toddler outcomes based on working alliance strength
- Shorter rifamycin-containing regimens show comparable efficacy to longer isoniazid monotherapy for latent tuberculosis infection
- ERAS protocols may optimize clinical outcomes and rehabilitation for pediatric patients with fractures
- Scleral-fixated intraocular lenses improve visual acuity and show low complication rates in pediatric eyes
- Propranolol and propafenone provide stable management for CALM2 mutation related LQTS/CPVT overlap in children
- Pediatric delirium affects 38% of critically ill children in meta-analysis
- FDA Approves Augmentin Es-600 (amoxicillin/clavulanate potassium) for Recurrent Acute Otitis Media in Children
- Multimodal lung-protective strategies reduce BPD risk in preterm infants
- Conservative management leads to improvement in Chinese children with Ménétrier disease
- Adjunctive steroids reduce mortality in adult TB meningitis patients but not in children
- Nalmefene reduces sufentanil-induced cough incidence to 11.3% at 0.1 μg/kg in children
- Imatinib achieves complete cytogenetic response in a pediatric patient with suspected chronic myeloid leukemia
- Benzodiazepines increase delirium and sleep fragmentation risk while dexmedetomidine shows mixed evidence in pediatric ICU
- Blood product removal reduces permanent shunting risk and mortality in infants with posthemorrhagic hydrocephalus
- Predictors of Polysomnography Progression in Children with Mild Sleep-Disordered Breathing
- Obstructive Sleep Apnea Affects Nearly Half of Cystic Fibrosis Patients
- Trained general practitioners achieve substantial agreement with radiologists in abdominal aortic aneurysm ultrasound screening
- Meta-analysis reveals significant disparities in childhood anthropometric failure across global regions
- Balloon dilation of the eustachian tube improves audiological outcomes in pediatric patients with ETD
- Arthroscopy-assisted physeal bar resection restores knee motion in toddler
- High-dose IVIG with phototherapy reduces exchange transfusion rates by 76% in neonatal hemolytic disease
- Coronal fragment treatment with calcium silicate bioceramic sealer maintains aesthetic stability in dental trauma
- Early postnatal antibiotic exposure increases BPD risk in very preterm infants across 11 studies
- Infliximab treatment achieved clinical remission in a pediatric patient with autoinflammation with infantile enterocolitis
- Single-stage reconstruction shows no significant difference compared to staged reconstruction for bowel continence
- WDR26 gene variants are associated with Skraban-Deardorff syndrome and delayed language development
- Behavioral therapy produces sustained improvements in tic symptoms for children and adolescents with Tourette syndrome
- Sarcopenic obesity may impair bone formation and reduce mineral content in children and adolescents
- Oxytocin use and high newborn weight are associated with increased episiotomy risk during vaginal birth
- Individuals with developmental dyslexia exhibit medium magnitude impairments in fine motor skills compared to neurotypical peers
- Short-course antibiotics cut complication risk by half in pediatric osteoarticular infections
- Balanced crystalloids reduce time to DKA resolution by 1.60 hours compared to 0.9% saline
- Preterm birth linked to higher pain intensity and heat pain thresholds in meta-analysis
- Lower lip capillary malformation occurs in all patients with CLAPO syndrome
- 30% of pediatric patients with migraine report at least one adverse event during pharmacological prophylaxis
- Dermatitis Herpetiformis prevalence in Celiac Disease patients is 6.8% with high heterogeneity
- Osteopetrosis in children: orthopaedic management guided by bone brittleness and fracture risk
- Aerobic exercise reduces subthreshold depressive symptoms in adolescents compared to psychoeducation
- Observational survey identifies determinants of Infant and Young Child Feeding practices in children with SAM
- Lactobacillus rhamnosus GG does not significantly impact composite outcomes in VLBW infants
- Rotarix PCV-free meets non-inferiority for seroconversion rates compared to Rotarix in infants
- Long-term relapse rate in children with convulsions and mild gastroenteritis is 9.8% (95% CI 5.2%-17.7%)
- SQ-LNS reduces hair cortisol concentration in children of mothers with limited schooling
- Liquefied petroleum gas cookstove intervention showed no significant effect on infant early child development
- Maternal age, BMI, and irregular folic acid supplementation are associated with higher birth defect risk
- Caesarean birth and perinatal antibiotics are associated with reduced gut microbial diversity
- Long-term exercise improves executive function in children with ADHD, meta-analysis finds
- Polymer-based materials provide comparable clinical performance for deep margin elevation in indirect restorations
- Nebulised Chinese herbal medicine as adjunctive therapy improves clinical effective rate in pediatric pneumonia
- Parent-targeted digital health interventions increase the odds of exclusive breastfeeding with an odds ratio of 2.58
- Refugee and asylum seeker status is associated with high prevalence of clinically significant sleep disturbances
- Ketogenic diet therapies improve seizure reduction rates in children and adults with drug-resistant epilepsy
- Monoclonal antibodies reduce RSV-related hospitalizations in premature infants with nirsevimab showing highest SUCRA values
- Thoracoscopic resection provides favorable outcomes for pediatric patients with extralobar pulmonary sequestration complicated by torsion
- Technology-based reading interventions yield small-to-moderate gains in elementary students with reading difficulties
- HFNC reduces treatment failure and PICU stay in pediatric bronchiolitis compared to LFNC
- Cannabidiol is associated with 49.9% seizure reduction in patients with Developmental and Epileptic Encephalopathies
- Childhood psychological abuse is significantly associated with suicidal ideation in college students
- Pediatric Langerhans Cell Histiocytosis presents with skull involvement in 48.8% of cases
- Child maltreatment prevalence reaches 38% among children and adolescents in Ethiopia
- Music education is associated with significant medium-sized improvements in executive function among children
- Girls exhibit greater sit-and-reach flexibility than boys across all ages from 3 to 16
- Children with posterior urethral valves and adverse prognostic features have 1.44 times higher CKD risk
- Clinical decision rules significantly reduce radiography for pediatric ankle injuries in emergency department settings
- Human milk fortifiers for preterm infants: a narrative review of current and investigational options
- RSV infection complicated by acute otitis media in 27.7% of children under 5
- Myopia prevalence among Malaysian children is estimated between 16% and 25% depending on diagnostic methods
- Nirsevimab and maternal RSVpreF vaccination show approximately 80% effectiveness against RSV-associated hospitalization in children