Specific biomarkers like CD4/CD8 ratio inversion and T-cell senescence markers indicate immune aging in HIV
New markers help track immune aging in people living with HIV
This systematic review evaluates candidate biomarkers of immune aging in adults living with HIV undergoing long-term antiretroviral therapy …
New markers like T-cell senescence and cytokine panels help doctors track how immune aging affects people living with HIV on long-term treat…
Once-weekly long-acting growth hormone shows comparable efficacy to daily growth hormone for children with short stature
Weekly growth hormone shows similar results to daily injections
This meta-analysis of 30 studies involving 3,287 patients found that once-weekly long-acting growth hormone (LAGH) provides comparable heigh…
A new review shows that once-weekly growth hormone injections work as well as daily shots for children with short stature.
MRG mutations correlate with worse overall survival and lower remission in NPM1-mutated AML
Specific gene mutations linked to worse outcomes in certain leukemia
This meta-analysis of 4,363 patients found that MRG mutations (such as ASXL1, BCOR, and EZH2) are associated with inferior overall survival …
New data shows that specific gene mutations can predict poorer survival and lower remission rates for patients with a specific type of leuke…
PFMT plus hormonal therapy cuts dysmenorrhea recurrence risk in endometriosis
Pelvic Floor Training May Reduce Endometriosis Pain Recurrence
This retrospective cohort study of 446 women with surgically confirmed endometriosis found that adding pelvic floor muscle training (PFMT) t…
Combining pelvic floor muscle training with hormonal therapy may significantly lower the risk of pain recurrence for women with endometriosi…
Treosulfan-fludarabine improves 24-month event-free survival to 65% versus 53% in AML patients
Treosulfan Shows Better Outcomes for Patients with Acute Myeloid Leukemia
This Phase 3 randomized trial subgroup analysis of 352 patients with AML undergoing alloHCT found treosulfan-fludarabine superior to reduced…
A new analysis of a Phase 3 trial suggests treosulfan may offer better survival rates and fewer complications for patients with acute myeloi…
SYK inhibitors show RR of 10.26 for durable platelet response in immune thrombocytopenia
New IgG-Pathway Inhibitors Show Promise for Immune Thrombocytopenia
This meta-analysis of randomized controlled trials evaluates IgG-pathway inhibitors, including SYK, FcRn, and BTK inhibitors, for immune thr…
New types of medications called IgG-pathway inhibitors may offer more durable platelet responses for adults with immune thrombocytopenia.
Dasatinib 50 mg maintains efficacy while reducing pleural effusion and thrombocytopenia in CP-CML
Lower Dasatinib Dose May Improve Tolerability for Leukemia Patients
This meta-analysis of 7 nonoverlapping reports compared dasatinib 50 mg and 100 mg in adults with chronic-phase chronic myeloid leukemia. Th…
A lower daily dose of dasatinib may offer similar effectiveness with fewer side effects for adults with chronic-phase chronic myeloid leukem…
Clinically significant CMV infection occurs in 9% of patients receiving bispecific antibodies for hematologic malignancies
Bispecific Antibodies Linked to Lower Rates of CMV Infection
This meta-analysis of 23 studies and a single-center cohort evaluated bispecific antibody use in multiple myeloma, B-cell lymphoma, and acut…
New data shows that patients receiving bispecific antibodies for certain blood cancers may have lower rates of serious CMV infections.
6-month IS value predicts MR4.5 attainment and TKI discontinuation eligibility in CML patients
Trial Shows Early Markers Predict Success in Chronic Myeloid Leukemia
This observational study of 431 patients with chronic myeloid leukemia (CML) on second-generation TKIs found that the 6-month IS value is a …
New data from a Phase 3 trial shows that early markers can help predict which patients with chronic myeloid leukemia may reach specific trea…
Cytotoxic T-cell state remodeling and HLA-B genetic associations drive immune pressure in aplastic anaemia
New research reveals how immune cells drive aplastic anaemia
This meta-analysis integrates single-cell RNA sequencing and genetic data to identify cytotoxic T-cell regulatory states in aplastic anaemia…
Researchers identified specific immune cell behaviors and genetic links that may explain why the body stops producing enough blood in aplast…
Elevated syndecan-1 levels correlate with severity and poor outcomes in patients with sepsis
Higher syndecan-1 levels linked to severe sepsis and poor outcomes
This meta-analysis of 4985 patients, including 3902 with sepsis, found significantly higher circulating syndecan-1 levels in sepsis patients…
A new analysis shows that higher levels of a specific protein can help doctors identify patients with the most severe forms of sepsis.
EBV prevalence varies widely across lymphoma subtypes, highest in ENKTL at 92.4%
EBV Presence Linked to Lymphoma Cases in People with HIV
This meta-analysis of 307 studies and over 21,140 lymphoma cases quantifies Epstein-Barr virus (EBV) prevalence across lymphoma subtypes, st…
A large review of over 21,000 cases shows that the Epstein-Barr virus is more common in certain lymphoma types among people living with HIV.
All Hematology Articles
- Specific biomarkers like CD4/CD8 ratio inversion and T-cell senescence markers indicate immune aging in HIV
- Once-weekly long-acting growth hormone shows comparable efficacy to daily growth hormone for children with short stature
- Treosulfan-fludarabine improves 24-month event-free survival to 65% versus 53% in AML patients
- PFMT plus hormonal therapy cuts dysmenorrhea recurrence risk in endometriosis
- MRG mutations correlate with worse overall survival and lower remission in NPM1-mutated AML
- SYK inhibitors show RR of 10.26 for durable platelet response in immune thrombocytopenia
- Dasatinib 50 mg maintains efficacy while reducing pleural effusion and thrombocytopenia in CP-CML
- Clinically significant CMV infection occurs in 9% of patients receiving bispecific antibodies for hematologic malignancies
- 6-month IS value predicts MR4.5 attainment and TKI discontinuation eligibility in CML patients
- Cytotoxic T-cell state remodeling and HLA-B genetic associations drive immune pressure in aplastic anaemia
- Elevated syndecan-1 levels correlate with severity and poor outcomes in patients with sepsis
- EBV prevalence varies widely across lymphoma subtypes, highest in ENKTL at 92.4%
- Local cooling techniques reduce immediate pain after subcutaneous heparin injection with SMD -0.64
- Deep learning for leukemia diagnosis faces fragmented research and limited multimodal integration in current literature
- Leukapheresis not clearly linked to lower 30-day mortality in AML with hyperleukocytosis
- Phage-induced mutations create fitness costs that enhance host immune clearance in bacterial infections
- Mosunetuzumab plus polatuzumab vedotin achieved a 100% overall response rate in Japanese patients with LBCL
- Extracellular vesicles in RA: biomarkers and therapeutic vehicles, but clinical utility remains unproven
- IV-PEG asparaginase compared to IM-EC in children with acute lymphoblastic leukemia
- Four specific miRNAs in extracellular vesicles satisfy high-tier causality for metabolic and inflammatory regulation
- FDA Approves Inrebic (fedratinib) for Intermediate-2 or High-Risk Myelofibrosis
- FDA Approves Jakafi (ruxolitinib) for Steroid-Refractory Acute Graft-Versus-Host Disease
- FDA Approves Vonjo (pacritinib) for Myelofibrosis with Low Platelet Counts
- ctDNA and immune profiling offer a pathway toward individualized treatment for recurrent colorectal cancer
- Susceptibility-guided combination therapy improves neurological status and reduces abscess size in a patient with nocardiosis
- Piezoelectric osteotomy reduces edema, ecchymosis, and pain in patients undergoing rhinoplasty
- Acupuncture Modalities Show Distinct Benefits for Trigeminal Neuralgia
- FDA Approves Sarclisa Escena (isatuximab-irfc) Subcutaneous for Multiple Myeloma
- Vivaray Hb pro shows 1.5 g/dL mean absolute error in hemoglobin measurement
- Immune microenvironment characterization provides a framework for precision immunotherapy in various thyroid cancer types
- Efgartigimod PH20 SC showed no significant difference versus placebo in primary ITP
- Avatrombopag shows 80.0% response rate and 2.82% thromboembolic event rate in adult immune thrombocytopenia
- Venetoclax plus intensive chemo yields 63.79% ORR in relapsed/refractory AML meta-analysis
- FDA Approves Besremi (interferon alfa-2b) for Polycythemia Vera
- AI-augmented screening improves hereditary hemolytic anemia detection with 92.8% pooled sensitivity
- Low-dose ATG plus PTCy shows no significant difference in acute GVHD compared to standard regimens
- Functional appliances induce significant three-dimensional condylar changes and forward positioning in Class II malocclusion
- Acute cellular senescence facilitates tissue repair while chronic accumulation drives intestinal fibrosis in Crohn's disease
- FDA Approves Argatroban in Sodium Chloride for Thrombosis in HIT and PCI
- FDA Approves Hympavzi (marstacimab) for Routine Prophylaxis in Hemophilia A and B Without Inhibitors
- OTUD7B acts as a context-dependent regulator in various cancers and inflammatory conditions
- Anatomical and immunological factors drive pathogenesis in plasma cell mastitis cases
- Precision diagnostics and novel biomarkers improve the management of graft-versus-host disease clinical spectrum
- 7-day venetoclax with intensive chemotherapy achieves 90.3% composite complete remission in AML
- Proximal gastrectomy offers shorter operative time but similar survival vs total gastrectomy in advanced gastric cancer
- Ianalumab plus eltrombopag extends time to treatment failure in primary ITP adults
- FDA Approves Ultomiris (ravulizumab-cwvz) for Generalized Myasthenia Gravis
- Platelet-derived DKK1 enhances leukocyte-platelet aggregation and recruits immune cells in Leishmaniasis models
- Zanubrutinib Delivers High Response Rates And Survival Benefits Across Diffuse Large B-Cell Lymphoma Patient Groups In This Meta-Analysis
- Recombinant ADAMTS13 shows no significant difference in acute TTP events versus standard therapy or placebo in phase 2 and 3 trials
- HMA-venetoclax yields 50% overall response rate in relapsed/refractory AML meta-analysis
- Systematic review reveals high prevalence of sickle cell disease across infants and youth in sub-Saharan Africa
- Non-pharmacological interventions in adult ICU patients did not improve health-related quality of life in this network meta-analysis
- NINJ1 targeting shows potential for multiple sclerosis and other neurological conditions but faces significant knowledge gaps
- Xatmep receives FDA approval for pediatric acute lymphoblastic leukemia and polyarticular juvenile idiopathic arthritis
- Reduced-intensity ATRA plus arsenic with GO or low-dose anthracycline improves event-free survival in high-risk APL
- Clinical and laboratory abnormalities linked to higher mortality in malaria patients with acute kidney injury
- Narrative review suggests idiotype-directed CAAR-T therapy remains hypothetical for B-cell malignancies
- FDA Approves Venclexta (venetoclax) for CLL/SLL and AML
- FDA Approves Argatroban for Thrombosis in Heparin-Induced Thrombocytopenia
- TEG-ROTEM guided transfusion may lower death and bleeding in cardiac surgery
- FDA Approves Inqovi (decitabine/cedazuridine) for Myelodysplastic Syndromes
- Scoping review examines imatinib gonadotoxicity in males with chronic myeloid leukemia or gastrointestinal stromal tumors
- Network meta-analysis of 107 RCTs on blood-invigorating Chinese herbal medicines for endometriosis
- Delphi guideline on Para athletics talent identification and development strategies
- Meta-analysis links HLA alleles and ADAMTS13 variants to thrombotic thrombocytopenic purpura risk
- Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma
- Meta-analysis finds no clear benefit of adding nutrition to BFR training for strength or hypertrophy in healthy adults
- Genetic variants in ABCB1 and ABCG2 raise imatinib trough levels in CML patients
- Systematic review and meta-analysis of interim FDG PET in large B-cell lymphoma patients
- FDA Approves Epysqli (eculizumab-sbja) for PNH, aHUS, and gMG
- Machine learning predicts recreational therapy engagement in veterans
- Systematic review and meta-analysis finds high prevalence of ocular manifestations in leukemia patients
- Fixed-duration subcutaneous mosunetuzumab shows favorable efficacy and safety versus IV in relapsed follicular lymphoma
- Meta-analysis links perinatal factors to childhood acute leukemia risk
- Meta-analysis links maternal infection in pregnancy to childhood ALL risk
- Longitudinal TCR profiling predicts EBV, CMV, and GVHD in 108 allo-HSCT recipients
- Systematic Review Links Lysosomal Pathways to Autoimmune Kidney Disease Progression
- Eight-gene signature associated with survival in patients with Diffuse Large B-cell lymphoma
- Meta-analysis associates emerging lesions after lutetium-177 therapy with worse overall survival in mCRPC
- Systematic review suggests partial glossectomy with speech therapy improves speech retention and reduces costs for oral cancer patients
- Eltrombopag monotherapy assessed in moderate aplastic anemia and unilineage bone marrow failure disorders
- Three Biomarkers Show High Diagnostic Accuracy for Ulcerative Colitis in Cohort Study
- Scoping review of wastewater-based surveillance for AMR and SARS-CoV-2 in GCC countries
- Narrative review discusses sarcopenia and intramuscular vaccination immune landscape gaps
- Network meta-analysis of vital pulp therapy success in mature permanent teeth with carious exposure
- Review summarizes fenofibrate, metformin, and MSC modulation in Primary Sjögren disease management
- Case report and literature review of ENKTL presenting with ocular symptoms and treated with GemOx
- Review of solitary plasmacytoma radiotherapy outcomes in Indian tertiary care
- Observational study identifies PF4-dependent antibodies in ELISA-negative HIT patients via functional testing
- FDA Approves Rytelo (telomerase inhibitor oligonucleotide) for transfusion-dependent anemia in low- to intermediate-1 risk MDS
- AMH Levels in Pediatric Cancer Patients Before and After Treatment
- Phase 2 trial tests single-dose IV iron isomaltoside in severe aortic stenosis with iron deficiency
- BR regimen shows survival outcomes in newly diagnosed Waldenstroms Macroglobulinemia patients
- Meta-analysis of HSCT with treosulfan in Ataxia Telangiectasia patients shows mixed survival outcomes and significant toxicities
- Meta-analysis finds non-clotting factor therapies reduce bleeding in congenital hemophilia
- Biomarkers and clinical factors show statistical associations with sepsis-induced coagulopathy in 37,459 patients
- Systematic review validates iPSC-derived organoids as models for ALS pathology compared to traditional 2D or animal models
- Hyperbaric oxygen pretreatment in autologous HSCT patients shows trends toward improved survival and reduced organ damage
- Recurrent low back pain accounts for disproportionate healthcare costs in Polish working-age adults
- Knowledge graph system for Jin San Zhen acupuncture therapy evaluation
- Hetrombopag increases platelet counts in children with immune thrombocytopenia in phase 3 trial
- Renizgamglogene autotemcel infusion showed engraftment and hemoglobin increases in severe sickle cell disease patients
- Phase 2 trial compares Inotuzumab Ozogamicin plus R-CVP for DLBCL patients unfit for anthracycline
- Phase 2 trial finds mezagitamab increases platelet counts in adults with persistent or chronic ITP
- In children with Ph+ ALL, TKI-based therapy reduced HSCT use while maintaining comparable outcomes versus Ph+ALL04
- Meta-analysis compares CAR T-cell constructs in 1540 relapsed/refractory B-ALL patients
- Direct pressure for 5 minutes reduces ecchymosis after venipuncture in older anticoagulated patients
- Systematic review explores necroptosis as a therapeutic target in multiple myeloma
- Point-of-care hemoglobin meters show high sensitivity but lower specificity versus analyzer in Ghanaian study
- Phase II trial shows high remission and survival with frontline ATRA-ATO for newly diagnosed APL
- Systematic review shows increased fat mass and decreased fat-free mass in children with acute lymphoblastic leukemia during treatment
- Observational study explores daratumumab resistance mechanisms in primary light-chain amyloidosis
- Gene therapy reduces bleeding rates and factor use in adults with severe hemophilia A
- CellSearch CMMC assay shows analytical sensitivity for non-invasive MRD monitoring in multiple myeloma
- Phase 1b trial finds tafasitamab combinations manageable in Japanese B-cell NHL patients
- Meta-analysis reports 53% 2-year overall survival after haploidentical HSCT in older adults
- Case report describes likely first autochthonous Chagas disease case in Missouri blood donor
- CDC updates blood lead reference value policy for US population
- Observational study finds race, ethnicity, and socioeconomic factors affect hemodialysis-associated S. aureus bloodstream infections
- Report examines use of recommended health care measures for sickle cell anemia complications in youth
- Case report links traditional eye cosmetic surma to lead poisoning in NYC family
- Case report associates elevated blood lead levels with kansa and pital metalware use in a pregnant woman
- Single case report describes durable response to nivolumab in relapsed ALK+ large B-cell lymphoma
- Damoctocog alfa pegol shows safety and maintained bleed protection in children with severe haemophilia A
- Phase 3 trial of damoctocog alfa pegol in previously treated children with severe haemophilia A
- R-CVP after radiotherapy improves progression-free survival in early-stage follicular lymphoma
- L-arginine shows no significant benefit for pain or hospital outcomes in sickle cell disease meta-analysis
- Case report: CMML initially diagnosed as ITP in one patient, stabilized with decitabine
- Imatinib reduces TNF-α levels in CML patients; persistent levels correlate with poor response
- Case report: obinutuzumab and venetoclax associated with nephrotic syndrome resolution in two CLL patients
- Siltuximab shows partial response in two iMCD-IPL cases with xanthelasma; skin lesions unchanged
- Spectral flow cytometry panel identifies hematopoietic lineages in mouse bone marrow models
- Perspective highlights diagnostic overlap between idiopathic multicentric Castleman disease and systemic lupus erythematosus
- Retrospective US claims analysis examines complications in non-transfusion-dependent thalassemia
- Case report describes management of Burkitt's lymphoma with concurrent HIV, CMV encephalitis, and salmonella bacteremia
- Phase I/II trial tests IMRT with chemotherapy before transplant for relapsed/refractory ALL/AML
- Phase 2 trial explores idelalisib plus ofatumumab in untreated CLL/SLL requiring treatment
- Phase III trial compares tisagenlecleucel to standard transplant in relapsed aggressive B-cell NHL
- Phase II trial compares quizartinib vs placebo with chemotherapy in FLT3 wild-type AML
- Daratumumab + Len/Dex shows ORR in relapsed/refractory multiple myeloma phase 1/2 trial
- Phase 2 Study of BGB-16673 in B-Cell Malignancies: Safety and Dose Findings
- Phase II Trial: HST-NEETs Shows Promise in HIV-Associated Lymphoma Post-ASCT
- Huaiqihuang Granule Improves Bleeding in Childhood CITP: 71.74% Effectiveness vs 45.65% Placebo
- Concizumab Reduces Bleeding in Hemophilia with Inhibitors: Median ABR 0.8 at 56 Weeks