Acute cellular senescence facilitates tissue repair while chronic accumulation drives intestinal fibrosis in Crohn's disease
Chronic cell aging may drive scarring in Crohn's disease
This systematic review examines the role of cellular senescence in intestinal fibrosis within Crohn's disease. The authors conclude that acu…
New research reveals how the timing of cellular aging determines whether your body heals properly or develops harmful scar tissue.
FDA Approves Argatroban in Sodium Chloride for Thrombosis in HIT and PCI
FDA approves new blood thinner for patients with rare clotting disorder.
The FDA approved argatroban in sodium chloride injection for prophylaxis or treatment of thrombosis in adult patients with heparin-induced t…
The FDA approved Argatroban in Sodium Chloride injection to prevent or treat blood clots in adults with heparin-induced thrombocytopenia (HI…
FDA Approves Hympavzi (marstacimab) for Routine Prophylaxis in Hemophilia A and B Without Inhibitors
FDA approves Hympavzi to prevent bleeding in hemophilia A and B.
The FDA approved Hympavzi (marstacimab) for routine prophylaxis to prevent or reduce bleeding episodes in patients 12 years and older with h…
The FDA approved Hympavzi (marstacimab) to prevent or reduce bleeding episodes in people 12 and older with hemophilia A or B without inhibit…
OTUD7B acts as a context-dependent regulator in various cancers and inflammatory conditions
Protein OTUD7B plays complex roles in cancer and heart health
This systematic review examines the molecular roles of OTUD7B across multiple malignancies and inflammatory models. The findings indicate th…
A protein called OTUD7B acts as a double-edged sword, helping some conditions while fueling the growth of others.
Anatomical and immunological factors drive pathogenesis in plasma cell mastitis cases
New insights into the causes and treatment of mastitis
This narrative review synthesizes the etiology, clinical manifestations, and treatment strategies for plasma cell mastitis. It highlights ho…
Doctors are identifying how structural issues and immune responses lead to chronic inflammation in breast tissue, helping clarify treatment …
Precision diagnostics and novel biomarkers improve the management of graft-versus-host disease clinical spectrum
New guidelines clarify treatment and diagnosis for graft-versus-host disease
This guideline provides a comprehensive overview of the graft-versus-host disease (GVHD) landscape, including acute and chronic forms. It sy…
New clinical guidelines offer a clearer look at how doctors can identify and treat the complex complications of graft-versus-host disease.
7-day venetoclax with intensive chemotherapy achieves 90.3% composite complete remission in AML
Trial shows venetoclax combined with chemotherapy for AML
This clinical trial of 259 newly diagnosed patients with acute myeloid leukemia found a 90.3% composite complete remission rate using a 7-da…
A new clinical trial shows that a short 7-day course of venetoclax combined with chemotherapy can achieve high remission rates in AML patien…
Proximal gastrectomy offers shorter operative time but similar survival vs total gastrectomy in advanced gastric cancer
Proximal Gastrectomy May Be Safe Option for Advanced Stomach Cancer
This systematic review and meta-analysis of propensity score-matched studies compared proximal gastrectomy (PG) to total gastrectomy (TG) in…
For patients with advanced stomach cancer after chemo, keeping part of the stomach may be as safe as removing it entirely, with similar surv…
Ianalumab plus eltrombopag extends time to treatment failure in primary ITP adults
Study tests ianalumab plus eltrombopag for adults with immune thrombocytopenia
This phase 3 randomized, double-blind trial in 152 adults with primary ITP and insufficient response to glucocorticoids found that ianalumab…
Adding ianalumab to standard therapy helped more adults with immune thrombocytopenia stay stable and avoid treatment failure compared to pla…
Platelet-derived DKK1 enhances leukocyte-platelet aggregation and recruits immune cells in Leishmaniasis models
Platelet protein may help fight Leishmaniasis in mice
This review examines the role of platelet-derived DKK1 in Leishmaniasis using BALB/c mice. The authors report enhanced leukocyte-platelet ag…
A review suggests a platelet protein could help the immune system fight Leishmaniasis by recruiting helpful cells and limiting parasite surv…
FDA Approves Ultomiris (ravulizumab-cwvz) for Generalized Myasthenia Gravis
FDA approves Ultomiris for adults with a form of myasthenia gravis.
The FDA approved Ultomiris (ravulizumab-cwvz) for adult patients with generalized myasthenia gravis (gMG) who are anti-acetylcholine recepto…
The FDA approved Ultomiris (ravulizumab-cwvz) for adults with generalized myasthenia gravis who have a specific antibody. This drug helps bl…
Zanubrutinib Delivers High Response Rates And Survival Benefits Across Diffuse Large B-Cell Lymphoma Patient Groups In This Meta-Analysis
Zanubrutinib shows high response rates in diffuse large B-cell lymphoma patients
A meta-analysis of 1,346 patients with diffuse large B-cell lymphoma shows zanubrutinib achieves high response rates and prolonged survival.…
Zanubrutinib helped 95 out of 100 previously untreated patients with diffuse large B-cell lymphoma respond to treatment in this analysis.
All Hematology Articles
- Acute cellular senescence facilitates tissue repair while chronic accumulation drives intestinal fibrosis in Crohn's disease
- FDA Approves Argatroban in Sodium Chloride for Thrombosis in HIT and PCI
- FDA Approves Hympavzi (marstacimab) for Routine Prophylaxis in Hemophilia A and B Without Inhibitors
- OTUD7B acts as a context-dependent regulator in various cancers and inflammatory conditions
- Anatomical and immunological factors drive pathogenesis in plasma cell mastitis cases
- Precision diagnostics and novel biomarkers improve the management of graft-versus-host disease clinical spectrum
- 7-day venetoclax with intensive chemotherapy achieves 90.3% composite complete remission in AML
- Proximal gastrectomy offers shorter operative time but similar survival vs total gastrectomy in advanced gastric cancer
- Ianalumab plus eltrombopag extends time to treatment failure in primary ITP adults
- FDA Approves Ultomiris (ravulizumab-cwvz) for Generalized Myasthenia Gravis
- Platelet-derived DKK1 enhances leukocyte-platelet aggregation and recruits immune cells in Leishmaniasis models
- Zanubrutinib Delivers High Response Rates And Survival Benefits Across Diffuse Large B-Cell Lymphoma Patient Groups In This Meta-Analysis
- Recombinant ADAMTS13 shows no significant difference in acute TTP events versus standard therapy or placebo in phase 2 and 3 trials
- HMA-venetoclax yields 50% overall response rate in relapsed/refractory AML meta-analysis
- Systematic review reveals high prevalence of sickle cell disease across infants and youth in sub-Saharan Africa
- Non-pharmacological interventions in adult ICU patients did not improve health-related quality of life in this network meta-analysis
- NINJ1 targeting shows potential for multiple sclerosis and other neurological conditions but faces significant knowledge gaps
- Xatmep receives FDA approval for pediatric acute lymphoblastic leukemia and polyarticular juvenile idiopathic arthritis
- Reduced-intensity ATRA plus arsenic with GO or low-dose anthracycline improves event-free survival in high-risk APL
- Clinical and laboratory abnormalities linked to higher mortality in malaria patients with acute kidney injury
- Narrative review suggests idiotype-directed CAAR-T therapy remains hypothetical for B-cell malignancies
- FDA Approves Venclexta (venetoclax) for CLL/SLL and AML
- FDA Approves Argatroban for Thrombosis in Heparin-Induced Thrombocytopenia
- TEG-ROTEM guided transfusion may lower death and bleeding in cardiac surgery
- FDA Approves Inqovi (decitabine/cedazuridine) for Myelodysplastic Syndromes
- Scoping review examines imatinib gonadotoxicity in males with chronic myeloid leukemia or gastrointestinal stromal tumors
- Network meta-analysis of 107 RCTs on blood-invigorating Chinese herbal medicines for endometriosis
- Delphi guideline on Para athletics talent identification and development strategies
- Meta-analysis links HLA alleles and ADAMTS13 variants to thrombotic thrombocytopenic purpura risk
- Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma
- Meta-analysis finds no clear benefit of adding nutrition to BFR training for strength or hypertrophy in healthy adults
- Genetic variants in ABCB1 and ABCG2 raise imatinib trough levels in CML patients
- Systematic review and meta-analysis of interim FDG PET in large B-cell lymphoma patients
- FDA Approves Epysqli (eculizumab-sbja) for PNH, aHUS, and gMG
- Machine learning predicts recreational therapy engagement in veterans
- Systematic review and meta-analysis finds high prevalence of ocular manifestations in leukemia patients
- Fixed-duration subcutaneous mosunetuzumab shows favorable efficacy and safety versus IV in relapsed follicular lymphoma
- Meta-analysis links perinatal factors to childhood acute leukemia risk
- Meta-analysis links maternal infection in pregnancy to childhood ALL risk
- Longitudinal TCR profiling predicts EBV, CMV, and GVHD in 108 allo-HSCT recipients
- Systematic Review Links Lysosomal Pathways to Autoimmune Kidney Disease Progression
- Eight-gene signature associated with survival in patients with Diffuse Large B-cell lymphoma
- Meta-analysis associates emerging lesions after lutetium-177 therapy with worse overall survival in mCRPC
- Systematic review suggests partial glossectomy with speech therapy improves speech retention and reduces costs for oral cancer patients
- Eltrombopag monotherapy assessed in moderate aplastic anemia and unilineage bone marrow failure disorders
- Three Biomarkers Show High Diagnostic Accuracy for Ulcerative Colitis in Cohort Study
- Scoping review of wastewater-based surveillance for AMR and SARS-CoV-2 in GCC countries
- Narrative review discusses sarcopenia and intramuscular vaccination immune landscape gaps
- Network meta-analysis of vital pulp therapy success in mature permanent teeth with carious exposure
- Review summarizes fenofibrate, metformin, and MSC modulation in Primary Sjögren disease management
- Case report and literature review of ENKTL presenting with ocular symptoms and treated with GemOx
- Review of solitary plasmacytoma radiotherapy outcomes in Indian tertiary care
- Observational study identifies PF4-dependent antibodies in ELISA-negative HIT patients via functional testing
- FDA Approves Rytelo (telomerase inhibitor oligonucleotide) for transfusion-dependent anemia in low- to intermediate-1 risk MDS
- AMH Levels in Pediatric Cancer Patients Before and After Treatment
- Phase 2 trial tests single-dose IV iron isomaltoside in severe aortic stenosis with iron deficiency
- BR regimen shows survival outcomes in newly diagnosed Waldenstroms Macroglobulinemia patients
- Meta-analysis of HSCT with treosulfan in Ataxia Telangiectasia patients shows mixed survival outcomes and significant toxicities
- Meta-analysis finds non-clotting factor therapies reduce bleeding in congenital hemophilia
- Biomarkers and clinical factors show statistical associations with sepsis-induced coagulopathy in 37,459 patients
- Systematic review validates iPSC-derived organoids as models for ALS pathology compared to traditional 2D or animal models
- Hyperbaric oxygen pretreatment in autologous HSCT patients shows trends toward improved survival and reduced organ damage
- Recurrent low back pain accounts for disproportionate healthcare costs in Polish working-age adults
- Knowledge graph system for Jin San Zhen acupuncture therapy evaluation
- Hetrombopag increases platelet counts in children with immune thrombocytopenia in phase 3 trial
- Renizgamglogene autotemcel infusion showed engraftment and hemoglobin increases in severe sickle cell disease patients
- Phase 2 trial compares Inotuzumab Ozogamicin plus R-CVP for DLBCL patients unfit for anthracycline
- Phase 2 trial finds mezagitamab increases platelet counts in adults with persistent or chronic ITP
- In children with Ph+ ALL, TKI-based therapy reduced HSCT use while maintaining comparable outcomes versus Ph+ALL04
- Meta-analysis compares CAR T-cell constructs in 1540 relapsed/refractory B-ALL patients
- Direct pressure for 5 minutes reduces ecchymosis after venipuncture in older anticoagulated patients
- Systematic review explores necroptosis as a therapeutic target in multiple myeloma
- Point-of-care hemoglobin meters show high sensitivity but lower specificity versus analyzer in Ghanaian study
- Phase II trial shows high remission and survival with frontline ATRA-ATO for newly diagnosed APL
- Systematic review shows increased fat mass and decreased fat-free mass in children with acute lymphoblastic leukemia during treatment
- Observational study explores daratumumab resistance mechanisms in primary light-chain amyloidosis
- Gene therapy reduces bleeding rates and factor use in adults with severe hemophilia A
- CellSearch CMMC assay shows analytical sensitivity for non-invasive MRD monitoring in multiple myeloma
- Phase 1b trial finds tafasitamab combinations manageable in Japanese B-cell NHL patients
- Meta-analysis reports 53% 2-year overall survival after haploidentical HSCT in older adults
- Case report describes likely first autochthonous Chagas disease case in Missouri blood donor
- CDC updates blood lead reference value policy for US population
- Observational study finds race, ethnicity, and socioeconomic factors affect hemodialysis-associated S. aureus bloodstream infections
- Report examines use of recommended health care measures for sickle cell anemia complications in youth
- Case report links traditional eye cosmetic surma to lead poisoning in NYC family
- Case report associates elevated blood lead levels with kansa and pital metalware use in a pregnant woman
- Single case report describes durable response to nivolumab in relapsed ALK+ large B-cell lymphoma
- Damoctocog alfa pegol shows safety and maintained bleed protection in children with severe haemophilia A
- Phase 3 trial of damoctocog alfa pegol in previously treated children with severe haemophilia A
- R-CVP after radiotherapy improves progression-free survival in early-stage follicular lymphoma
- L-arginine shows no significant benefit for pain or hospital outcomes in sickle cell disease meta-analysis
- Case report: CMML initially diagnosed as ITP in one patient, stabilized with decitabine
- Imatinib reduces TNF-α levels in CML patients; persistent levels correlate with poor response
- Case report: obinutuzumab and venetoclax associated with nephrotic syndrome resolution in two CLL patients
- Siltuximab shows partial response in two iMCD-IPL cases with xanthelasma; skin lesions unchanged
- Spectral flow cytometry panel identifies hematopoietic lineages in mouse bone marrow models
- Perspective highlights diagnostic overlap between idiopathic multicentric Castleman disease and systemic lupus erythematosus
- Retrospective US claims analysis examines complications in non-transfusion-dependent thalassemia
- Case report describes management of Burkitt's lymphoma with concurrent HIV, CMV encephalitis, and salmonella bacteremia
- Phase I/II trial tests IMRT with chemotherapy before transplant for relapsed/refractory ALL/AML
- Phase 2 trial explores idelalisib plus ofatumumab in untreated CLL/SLL requiring treatment
- Phase III trial compares tisagenlecleucel to standard transplant in relapsed aggressive B-cell NHL
- Phase II trial compares quizartinib vs placebo with chemotherapy in FLT3 wild-type AML
- Daratumumab + Len/Dex shows ORR in relapsed/refractory multiple myeloma phase 1/2 trial
- Phase 2 Study of BGB-16673 in B-Cell Malignancies: Safety and Dose Findings
- Phase II Trial: HST-NEETs Shows Promise in HIV-Associated Lymphoma Post-ASCT
- Huaiqihuang Granule Improves Bleeding in Childhood CITP: 71.74% Effectiveness vs 45.65% Placebo
- Concizumab Reduces Bleeding in Hemophilia with Inhibitors: Median ABR 0.8 at 56 Weeks