Hematology

All Hematology Articles

• Mini midlines provide superior puncture success and safety compared to peripheral intravenous catheters
• Rituximab monotherapy prolongs time to new treatment but not overall survival in low-tumor-burden follicular lymphoma
• C5aR1 blockade reduces pain-like behavior in chemical osteoarthritis models but lacks clinical validation
• Interleukin-22 promotes tissue regeneration but shows inconsistent effects on barrier function in inflammatory bowel disease
• Ponatinib combined with blinatumomab achieves 84% overall survival in Philadelphia chromosome-positive acute lymphoblastic leukemia
• Hydroxyurea shows statistically significant lower odds for non-proliferative and proliferative sickle cell retinopathy
• FDA Approves Heparin Sodium in 0.45% Sodium Chloride Injection for Thromboembolic Indications
• FDA Approves Monoferric (ferric derisomaltose) for Iron Deficiency Anemia in Adults
• Local ancestry-aware GWAS finds 38 European-tract and 12 African-tract loci for eGFR in sickle cell disease
• Mitapivat Improves Haemoglobin Concentration in Patients with Chronic Sickle Cell Disease
• FDA Approves Reblozyl (luspatercept-aamt) for Anemia in Beta Thalassemia and MDS
• Forty independent genetic loci associated with acute chest syndrome occurrence in sickle cell disease patients
• Consider POAML in Progressive Eyelid Swelling, Even in Young Women
• CSF IL-6 and MCP-1 levels distinguish neuropsychiatric involvement in systemic lupus erythematosus patients
• Sickle cell trait is associated with increased risk of kidney disease, pulmonary embolism, and anemia
• Evaluating Cytokine and Molecular Biomarkers for Diagnosing Primary Vitreoretinal Lymphoma
• BTK inhibitors do not significantly increase second primary malignancy risk in B-cell lymphoma patients
• Blinatumomab plus chemotherapy improves disease-free and overall survival in pediatric B-ALL
• RBC alloimmunization affects 8.76% of transfused sickle cell patients in resource-limited settings
• Mesenchymal stromal cells and MSC-derived extracellular vesicles may reprogram neuroimmune responses in neurodegenerative diseases
• Mechanistic-driven diagnosis and therapy shift focus from platelet counts to underlying pathophysiology of thrombocytopenia
• FDA Approves Gazyva (obinutuzumab) for Chronic Lymphocytic Leukemia
• FDA Approves Scemblix (asciminib) for Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
• Specific biomarkers like CD4/CD8 ratio inversion and T-cell senescence markers indicate immune aging in HIV
• Once-weekly long-acting growth hormone shows comparable efficacy to daily growth hormone for children with short stature
• Treosulfan-fludarabine improves 24-month event-free survival to 65% versus 53% in AML patients
• PFMT plus hormonal therapy cuts dysmenorrhea recurrence risk in endometriosis
• MRG mutations correlate with worse overall survival and lower remission in NPM1-mutated AML
• SYK inhibitors show RR of 10.26 for durable platelet response in immune thrombocytopenia
• Dasatinib 50 mg maintains efficacy while reducing pleural effusion and thrombocytopenia in CP-CML
• Clinically significant CMV infection occurs in 9% of patients receiving bispecific antibodies for hematologic malignancies
• 6-month IS value predicts MR4.5 attainment and TKI discontinuation eligibility in CML patients
• Cytotoxic T-cell state remodeling and HLA-B genetic associations drive immune pressure in aplastic anaemia
• Elevated syndecan-1 levels correlate with severity and poor outcomes in patients with sepsis
• EBV prevalence varies widely across lymphoma subtypes, highest in ENKTL at 92.4%
• Local cooling techniques reduce immediate pain after subcutaneous heparin injection with SMD -0.64
• Deep learning for leukemia diagnosis faces fragmented research and limited multimodal integration in current literature
• Leukapheresis not clearly linked to lower 30-day mortality in AML with hyperleukocytosis
• Phage-induced mutations create fitness costs that enhance host immune clearance in bacterial infections
• Mosunetuzumab plus polatuzumab vedotin achieved a 100% overall response rate in Japanese patients with LBCL
• Extracellular vesicles in RA: biomarkers and therapeutic vehicles, but clinical utility remains unproven
• IV-PEG asparaginase compared to IM-EC in children with acute lymphoblastic leukemia
• Four specific miRNAs in extracellular vesicles satisfy high-tier causality for metabolic and inflammatory regulation
• FDA Approves Inrebic (fedratinib) for Intermediate-2 or High-Risk Myelofibrosis
• FDA Approves Jakafi (ruxolitinib) for Steroid-Refractory Acute Graft-Versus-Host Disease
• FDA Approves Vonjo (pacritinib) for Myelofibrosis with Low Platelet Counts
• ctDNA and immune profiling offer a pathway toward individualized treatment for recurrent colorectal cancer
• Susceptibility-guided combination therapy improves neurological status and reduces abscess size in a patient with nocardiosis
• Piezoelectric osteotomy reduces edema, ecchymosis, and pain in patients undergoing rhinoplasty
• Acupuncture Modalities Show Distinct Benefits for Trigeminal Neuralgia
• FDA Approves Sarclisa Escena (isatuximab-irfc) Subcutaneous for Multiple Myeloma
• Vivaray Hb pro shows 1.5 g/dL mean absolute error in hemoglobin measurement
• Immune microenvironment characterization provides a framework for precision immunotherapy in various thyroid cancer types
• Efgartigimod PH20 SC showed no significant difference versus placebo in primary ITP
• Avatrombopag shows 80.0% response rate and 2.82% thromboembolic event rate in adult immune thrombocytopenia
• Venetoclax plus intensive chemo yields 63.79% ORR in relapsed/refractory AML meta-analysis
• FDA Approves Besremi (interferon alfa-2b) for Polycythemia Vera
• AI-augmented screening improves hereditary hemolytic anemia detection with 92.8% pooled sensitivity
• Low-dose ATG plus PTCy shows no significant difference in acute GVHD compared to standard regimens
• Functional appliances induce significant three-dimensional condylar changes and forward positioning in Class II malocclusion
• Acute cellular senescence facilitates tissue repair while chronic accumulation drives intestinal fibrosis in Crohn's disease
• FDA Approves Argatroban in Sodium Chloride for Thrombosis in HIT and PCI
• FDA Approves Hympavzi (marstacimab) for Routine Prophylaxis in Hemophilia A and B Without Inhibitors
• OTUD7B acts as a context-dependent regulator in various cancers and inflammatory conditions
• Anatomical and immunological factors drive pathogenesis in plasma cell mastitis cases
• Precision diagnostics and novel biomarkers improve the management of graft-versus-host disease clinical spectrum
• 7-day venetoclax with intensive chemotherapy achieves 90.3% composite complete remission in AML
• Proximal gastrectomy offers shorter operative time but similar survival vs total gastrectomy in advanced gastric cancer
• Ianalumab plus eltrombopag extends time to treatment failure in primary ITP adults
• FDA Approves Ultomiris (ravulizumab-cwvz) for Generalized Myasthenia Gravis
• Platelet-derived DKK1 enhances leukocyte-platelet aggregation and recruits immune cells in Leishmaniasis models
• Zanubrutinib Delivers High Response Rates And Survival Benefits Across Diffuse Large B-Cell Lymphoma Patient Groups In This Meta-Analysis
• Recombinant ADAMTS13 shows no significant difference in acute TTP events versus standard therapy or placebo in phase 2 and 3 trials
• HMA-venetoclax yields 50% overall response rate in relapsed/refractory AML meta-analysis
• Systematic review reveals high prevalence of sickle cell disease across infants and youth in sub-Saharan Africa
• Non-pharmacological interventions in adult ICU patients did not improve health-related quality of life in this network meta-analysis
• NINJ1 targeting shows potential for multiple sclerosis and other neurological conditions but faces significant knowledge gaps
• Xatmep receives FDA approval for pediatric acute lymphoblastic leukemia and polyarticular juvenile idiopathic arthritis
• Reduced-intensity ATRA plus arsenic with GO or low-dose anthracycline improves event-free survival in high-risk APL
• Clinical and laboratory abnormalities linked to higher mortality in malaria patients with acute kidney injury
• Narrative review suggests idiotype-directed CAAR-T therapy remains hypothetical for B-cell malignancies
• FDA Approves Venclexta (venetoclax) for CLL/SLL and AML
• FDA Approves Argatroban for Thrombosis in Heparin-Induced Thrombocytopenia
• TEG-ROTEM guided transfusion may lower death and bleeding in cardiac surgery
• FDA Approves Inqovi (decitabine/cedazuridine) for Myelodysplastic Syndromes
• Scoping review examines imatinib gonadotoxicity in males with chronic myeloid leukemia or gastrointestinal stromal tumors
• Network meta-analysis of 107 RCTs on blood-invigorating Chinese herbal medicines for endometriosis
• Delphi guideline on Para athletics talent identification and development strategies
• Meta-analysis links HLA alleles and ADAMTS13 variants to thrombotic thrombocytopenic purpura risk
• Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma
• Meta-analysis finds no clear benefit of adding nutrition to BFR training for strength or hypertrophy in healthy adults
• Genetic variants in ABCB1 and ABCG2 raise imatinib trough levels in CML patients
• Systematic review and meta-analysis of interim FDG PET in large B-cell lymphoma patients
• FDA Approves Epysqli (eculizumab-sbja) for PNH, aHUS, and gMG
• Machine learning predicts recreational therapy engagement in veterans
• Systematic review and meta-analysis finds high prevalence of ocular manifestations in leukemia patients
• Fixed-duration subcutaneous mosunetuzumab shows favorable efficacy and safety versus IV in relapsed follicular lymphoma
• Meta-analysis links perinatal factors to childhood acute leukemia risk
• Meta-analysis links maternal infection in pregnancy to childhood ALL risk
• Longitudinal TCR profiling predicts EBV, CMV, and GVHD in 108 allo-HSCT recipients
• Systematic Review Links Lysosomal Pathways to Autoimmune Kidney Disease Progression
• Eight-gene signature associated with survival in patients with Diffuse Large B-cell lymphoma
• Meta-analysis associates emerging lesions after lutetium-177 therapy with worse overall survival in mCRPC
• Systematic review suggests partial glossectomy with speech therapy improves speech retention and reduces costs for oral cancer patients
• Eltrombopag monotherapy assessed in moderate aplastic anemia and unilineage bone marrow failure disorders
• Three Biomarkers Show High Diagnostic Accuracy for Ulcerative Colitis in Cohort Study
• Scoping review of wastewater-based surveillance for AMR and SARS-CoV-2 in GCC countries
• Narrative review discusses sarcopenia and intramuscular vaccination immune landscape gaps
• Network meta-analysis of vital pulp therapy success in mature permanent teeth with carious exposure
• Review summarizes fenofibrate, metformin, and MSC modulation in Primary Sjögren disease management
• Case report and literature review of ENKTL presenting with ocular symptoms and treated with GemOx
• Review of solitary plasmacytoma radiotherapy outcomes in Indian tertiary care
• Observational study identifies PF4-dependent antibodies in ELISA-negative HIT patients via functional testing
• FDA Approves Rytelo (telomerase inhibitor oligonucleotide) for transfusion-dependent anemia in low- to intermediate-1 risk MDS
• AMH Levels in Pediatric Cancer Patients Before and After Treatment
• Phase 2 trial tests single-dose IV iron isomaltoside in severe aortic stenosis with iron deficiency
• BR regimen shows survival outcomes in newly diagnosed Waldenstroms Macroglobulinemia patients
• Meta-analysis of HSCT with treosulfan in Ataxia Telangiectasia patients shows mixed survival outcomes and significant toxicities
• Meta-analysis finds non-clotting factor therapies reduce bleeding in congenital hemophilia
• Biomarkers and clinical factors show statistical associations with sepsis-induced coagulopathy in 37,459 patients
• Systematic review validates iPSC-derived organoids as models for ALS pathology compared to traditional 2D or animal models
• Hyperbaric oxygen pretreatment in autologous HSCT patients shows trends toward improved survival and reduced organ damage
• Recurrent low back pain accounts for disproportionate healthcare costs in Polish working-age adults
• Knowledge graph system for Jin San Zhen acupuncture therapy evaluation
• Hetrombopag increases platelet counts in children with immune thrombocytopenia in phase 3 trial
• Renizgamglogene autotemcel infusion showed engraftment and hemoglobin increases in severe sickle cell disease patients
• Phase 2 trial compares Inotuzumab Ozogamicin plus R-CVP for DLBCL patients unfit for anthracycline
• Phase 2 trial finds mezagitamab increases platelet counts in adults with persistent or chronic ITP
• In children with Ph+ ALL, TKI-based therapy reduced HSCT use while maintaining comparable outcomes versus Ph+ALL04
• Meta-analysis compares CAR T-cell constructs in 1540 relapsed/refractory B-ALL patients
• Direct pressure for 5 minutes reduces ecchymosis after venipuncture in older anticoagulated patients
• Systematic review explores necroptosis as a therapeutic target in multiple myeloma
• Point-of-care hemoglobin meters show high sensitivity but lower specificity versus analyzer in Ghanaian study
• Phase II trial shows high remission and survival with frontline ATRA-ATO for newly diagnosed APL
• Systematic review shows increased fat mass and decreased fat-free mass in children with acute lymphoblastic leukemia during treatment
• Observational study explores daratumumab resistance mechanisms in primary light-chain amyloidosis
• Gene therapy reduces bleeding rates and factor use in adults with severe hemophilia A
• CellSearch CMMC assay shows analytical sensitivity for non-invasive MRD monitoring in multiple myeloma
• Phase 1b trial finds tafasitamab combinations manageable in Japanese B-cell NHL patients
• Meta-analysis reports 53% 2-year overall survival after haploidentical HSCT in older adults
• Case report describes likely first autochthonous Chagas disease case in Missouri blood donor
• CDC updates blood lead reference value policy for US population
• Observational study finds race, ethnicity, and socioeconomic factors affect hemodialysis-associated S. aureus bloodstream infections
• Report examines use of recommended health care measures for sickle cell anemia complications in youth
• Case report links traditional eye cosmetic surma to lead poisoning in NYC family
• Case report associates elevated blood lead levels with kansa and pital metalware use in a pregnant woman
• Single case report describes durable response to nivolumab in relapsed ALK+ large B-cell lymphoma
• Damoctocog alfa pegol shows safety and maintained bleed protection in children with severe haemophilia A
• Phase 3 trial of damoctocog alfa pegol in previously treated children with severe haemophilia A
• R-CVP after radiotherapy improves progression-free survival in early-stage follicular lymphoma
• L-arginine shows no significant benefit for pain or hospital outcomes in sickle cell disease meta-analysis
• Case report: CMML initially diagnosed as ITP in one patient, stabilized with decitabine
• Imatinib reduces TNF-α levels in CML patients; persistent levels correlate with poor response
• Case report: obinutuzumab and venetoclax associated with nephrotic syndrome resolution in two CLL patients
• Siltuximab shows partial response in two iMCD-IPL cases with xanthelasma; skin lesions unchanged
• Spectral flow cytometry panel identifies hematopoietic lineages in mouse bone marrow models
• Perspective highlights diagnostic overlap between idiopathic multicentric Castleman disease and systemic lupus erythematosus
• Retrospective US claims analysis examines complications in non-transfusion-dependent thalassemia
• Case report describes management of Burkitt's lymphoma with concurrent HIV, CMV encephalitis, and salmonella bacteremia
• Phase I/II trial tests IMRT with chemotherapy before transplant for relapsed/refractory ALL/AML
• Phase 2 trial explores idelalisib plus ofatumumab in untreated CLL/SLL requiring treatment
• Phase III trial compares tisagenlecleucel to standard transplant in relapsed aggressive B-cell NHL
• Phase II trial compares quizartinib vs placebo with chemotherapy in FLT3 wild-type AML
• Daratumumab + Len/Dex shows ORR in relapsed/refractory multiple myeloma phase 1/2 trial
• Phase 2 Study of BGB-16673 in B-Cell Malignancies: Safety and Dose Findings
• Phase II Trial: HST-NEETs Shows Promise in HIV-Associated Lymphoma Post-ASCT
• Huaiqihuang Granule Improves Bleeding in Childhood CITP: 71.74% Effectiveness vs 45.65% Placebo
• Concizumab Reduces Bleeding in Hemophilia with Inhibitors: Median ABR 0.8 at 56 Weeks