Intraosseous-first access in adult cardiac arrest more likely harmful than beneficial
Intravenous access is more likely to improve survival in cardiac arrest
In a Bayesian reanalysis of 6,082 out-of-hospital cardiac arrests, intraosseous-first access was 81.6% likely to be inferior to intravenous-…
New data suggests that starting with intravenous access instead of bone-based access may improve survival for patients in cardiac arrest.
Enteral feeding delivery methods in critical illness: network meta-analysis protocol targets feeding intolerance
No Results Yet: Feeding Method Study for Critically Ill Still in Planning
This is a protocol for a systematic review and network meta-analysis comparing continuous, cyclic, intermittent, and bolus gastric enteral f…
A planned review will compare four ways of tube-feeding critically ill patients, but no results exist yet. Here's what that means.
Third-child fertility intention stays low at 6.6% in Eastern China after policy shift
Fertility intentions remain low in Eastern China after policy changes
This systematic review and meta-analysis examined fertility intention in the reproductive-age population of Eastern China following the thre…
Despite new policies, only a small number of parents in Eastern China plan to have a third child.
Prehospital whole blood resuscitation does not differ from standard blood components in 24-hour mortality
Whole blood and standard blood components show similar survival rates
This meta-analysis of 3 trials involving 2048 adult patients with traumatic haemorrhagic shock found no significant difference in 24-hour or…
New data shows that using whole blood instead of standard blood components does not change survival rates for patients in traumatic shock.
Lactated Ringer's reduces progression to severe acute pancreatitis and local complications compared to normal saline
Lactated Ringer's May Lower Severe Pancreatitis Risk Compared to Normal Saline
This systematic review and network meta-analysis of 1216 patients found that Lactated Ringer's (LR) significantly reduced progression to sev…
A review of 1,216 patients found that Lactated Ringer's fluid may cut the chance of severe acute pancreatitis compared with normal saline.
Echocardiographic assessment identifies long-term myocardial dysfunction in patients with burns, sepsis, and trauma
Heart Damage Found in Patients with Burns, Sepsis, and Trauma
This meta-analysis of 47 studies involving 3,117 patients identifies long-term myocardial dysfunction in survivors of burns, sepsis, and tra…
New analysis shows that patients surviving severe burns, sepsis, and major trauma may experience long-term heart muscle dysfunction.
Serum NSE and S100B Rise in Sepsis-Associated Encephalopathy
NSE and S100B Proteins May Help Identify Sepsis Brain Injury
A meta-analysis of 722 patients finds serum NSE and S100B significantly elevated in sepsis-associated encephalopathy versus sepsis alone.
New research suggests that measuring specific proteins in the blood could help doctors identify brain complications in patients with sepsis …
Virtual reality provides restorative escape and active participation for patients in intensive care units
Virtual reality offers patients a way to escape ICU distress
This qualitative systematic review and thematic synthesis of 247 patients explores the use of virtual reality (VR) in intensive care units. …
Virtual reality can help patients in intensive care move from passive endurance to active participation in their own recovery.
Pre-admission frailty and functional dependency are associated with higher all-cause mortality in ICU patients
Frailty and physical dependence increase risk for ICU patients
This meta-analysis of 55 observational studies indicates that pre-admission frailty and functional dependency are associated with higher mor…
Patients who are physically frail or dependent before entering the ICU face a much higher risk of death during their stay.
Epinephrine and norepinephrine show no significant difference from dopamine in neonatal septic shock
Trial shows no difference between dopamine and other drugs for infants
This meta-analysis of neonates with fluid-refractory septic shock found no significant difference between epinephrine or norepinephrine and …
New data shows that epinephrine and norepinephrine do not perform better than dopamine for treating severe shock in newborns.
Endoscopic transnasal removal is the primary reported management for patients with intranasal teeth
Doctors review common symptoms and risks of intranasal teeth
This narrative review synthesizes 170 patient records from 139 articles regarding the management of intranasal teeth. The authors conclude t…
A review of 170 cases shows that extra teeth in the nasal passage often cause pain, blockage, and discharge, requiring careful surgical remo…
Information ecology theory provides a conceptual framework for digital medical consumables asset management systems
New framework uses information ecology to manage medical supplies
This narrative review explores the construction of a digital medical consumables asset management system based on information ecology theory…
A new conceptual framework uses information ecology to help hospitals manage medical supplies more effectively through a digital management …
All Emergency Medicine Articles
- Intraosseous-first access in adult cardiac arrest more likely harmful than beneficial
- Enteral feeding delivery methods in critical illness: network meta-analysis protocol targets feeding intolerance
- Third-child fertility intention stays low at 6.6% in Eastern China after policy shift
- Lactated Ringer's reduces progression to severe acute pancreatitis and local complications compared to normal saline
- Serum NSE and S100B Rise in Sepsis-Associated Encephalopathy
- Pre-admission frailty and functional dependency are associated with higher all-cause mortality in ICU patients
- Echocardiographic assessment identifies long-term myocardial dysfunction in patients with burns, sepsis, and trauma
- Epinephrine and norepinephrine show no significant difference from dopamine in neonatal septic shock
- Prehospital whole blood resuscitation does not differ from standard blood components in 24-hour mortality
- Virtual reality provides restorative escape and active participation for patients in intensive care units
- Endoscopic transnasal removal is the primary reported management for patients with intranasal teeth
- Information ecology theory provides a conceptual framework for digital medical consumables asset management systems
- Rural setting is associated with 23% higher odds of death in emergency and trauma care
- Impact of Early Vasopressor Therapy and Restricted Fluids in Septic Shock Management
- Physical ICU rehabilitation is potentially safe and improves mobility scores in adults with traumatic brain injury
- Antiseizure medication prophylaxis shows no significant difference in mortality or functional outcomes in aneurysmal subarachnoid hemorrhage
- Higher H3.1 nucleosome levels associate with 48% increased 28-day mortality in septic shock
- Phoenix Sepsis Criteria outperforms IPSCC criteria for pediatric in-hospital mortality risk stratification
- Self-management for motor functional neurological disorder shows limited but promising evidence
- AI-driven medical dataset quality enhancement improves statistical fidelity and downstream utility in select modalities
- Non-surgical management including physical therapy and NSAIDs may improve pain in TFCC tears
- Elevated BMI is associated with lower short-term and long-term mortality in adult sepsis patients
- Ketamine-based sedation reduces ICU length of stay and delirium incidence in critically ill patients
- Sepsis-associated delirium affects 43% of ICU patients, mechanical ventilation strongest risk factor
- Impact of Evidence Based Feeding Protocols on Outcomes in Critically Ill Adults
- Evaluating Intensive Nursing Interventions for Managing Delirium in Intensive Care Units
- Non-invasive biomarkers show promise for managing acute rejection in heart transplant recipients
- Machine learning and deep learning models achieve a pooled AUROC of 0.913 for sepsis prediction
- Self-management interventions for arteriovenous fistulas vary in duration, frequency, and theoretical framework
- Multicomponent telehealth-based rehabilitation improves quality of life and reduces mortality in acute hypoxemic respiratory failure
- Obstructive sleep apnea is associated with a 2- to 3-fold increase in stroke risk
- Admission hypoalbuminemia is associated with increased mortality and acute kidney injury in burn patients
- Impact of Heart Failure Medications and Ventilation on Duchenne Muscular Dystrophy Survival
- Standardized testing frameworks are needed to improve safety of 3D-printed surgical devices in austere environments
- Serum lactate levels associated with 1.40 odds of unfavorable neurobehavioral outcome in pediatric cardiac arrest
- Pantoprazole Benefits COVID-19 ICU Patients Without Raising Mortality
- Early vasopressin initiation in septic shock shows mixed mortality outcomes across different study designs
- Bystander CPR increases 30-day survival odds by 50% in out-of-hospital cardiac arrest
- Impact of Pre-Weaning Fluid Balance on Success Rates in Mechanically Ventilated Patients
- Early Feeding in VLBW Infants Safe, Cuts Sepsis Risk
- Volume-controlled mechanical ventilation shows no difference in ROSC compared to manual ventilation in cardiac arrest
- Mechanical Insufflation-Exsufflation Improves Sputum Clearance in Ventilated ICU Adults
- Neutrophil-to-lymphocyte ratio shows 83.9% sensitivity and 83.9% specificity distinguishing dengue from COVID-19
- Lumbar puncture identifies subarachnoid blood while CT angiography facilitates rapid vascular assessment in SAH
- Stem cell-derived exosomes facilitate cutaneous wound healing and attenuate scarring via signaling pathway modulation
- Butyrylcholinesterase activity predicts in-hospital mortality in critically ill adults with sepsis
- Risk prediction models demonstrate good performance for identifying patients at risk of postherpetic neuralgia
- Ultrasound-indicated cerclage most consistently benefits high-risk singleton pregnancies with prior spontaneous preterm birth
- Evaluating Carbocisteine and Hypertonic Saline for Management of Acute Respiratory Failure
- COVID-19 pandemic associated with lower screening participation and higher mortality in colorectal cancer patients
- Physical rehabilitation improves muscle strength and reduces ICU-acquired weakness in critically ill adults
- Chinese stroke policy shows three-stage progression toward system-embedded and quality-oriented governance structures
- Alexithymia and interoceptive disturbances show consistent links with functional neurological disorder
- Syringe pump alarm misinterpretation can lead to local anesthetic overdose in patients with acute pancreatitis
- Telemedicine Intervention Impacts Spontaneous Breathing Trial Frequency and Ventilation Duration
- Expert consensus recommends universal screening and oral iron therapy for pediatric iron deficiency anemia
- Short mechanical ventilation after successful spontaneous breathing trials may reduce reintubation risk in critically ill adults
- Large language models offer potential benefits and significant challenges for emergency medicine education
- STR genotyping confirms gestational origin of pelvic choriocarcinoma, guiding risk score revision
- Tachypnoea at 60 breaths per minute increases odds of mortality in infants with sepsis
- Hyperphosphatemia is associated with increased ICU and hospital mortality in adult intensive care patients
- Role-modeling video prebriefing improves metacognition and ALS performance among novice ward nurses
- High MAP target of 77 mmHg reduces pulmonary vascular resistance in OHCA survivors
- IgM-enriched immunoglobulin shows directionally favorable but statistically inconclusive results for short-term mortality in sepsis
- Plasma ANXA3 shows superior predictive accuracy for sepsis compared to PCT, IL-6, and SOFA
- Levetiracetam lowers early seizure risk versus phenytoin after neurosurgery, but evidence is weak
- Skin perfusion parameters Mottling Score, CRT, and PPI correlate with higher mortality in sepsis patients
- Sepsis-induced neuromuscular dysfunction affects 60% of ICU adults, pooled meta-analysis finds
- Mechanical CPR does not show statistically significant difference from manual CPR for chest injuries
- Preventive medicine training gaps persist in field epidemiology and emergency response after COVID-19
- Sensory stimulation reduces delirium incidence and duration in ICU patients across meta-analyzed trials
- PEEP Valve in Bag-Valve-Mask CPR for Cardiac Arrest Outcomes
- Efficacy of Resuscitative Endovascular Balloon Occlusion of the Aorta in Hemorrhagic Shock
- PPI Guided Fluid Resuscitation Reduces Incidence of Acute Skin Failure in Critically Ill Patients
- Bleeding, sepsis, and liver impairment each independently raise thrombocytopenia risk in ICU patients
- Miller pyramid based HeartCode BLS teaching improves theoretical knowledge and CPR skills in nursing students
- Sanjad–Sakati syndrome requires urgent calcium correction, airway stabilization, and lifelong vitamin D therapy
- D-dimer shows moderate diagnostic potential for ruling out deep vein thrombosis after total joint arthroplasty
- Flow-controlled expiration (FLEX) significantly improves arterial oxygenation in horses compared to volume-controlled ventilation
- Manual pressure augmentation did not improve survival to hospital discharge in shockable OHCA
- Hyperoxygenation target (PaO2: 100-150 mmHg) reduces 28-day mortality in patients with sepsis
- Standard cardiopulmonary resuscitation improves survival rates in patients with out-of-hospital cardiac arrest
- Chelsea Critical Care Physical Assessment tool shows high content validity and excellent inter-rater reliability
- Higher mechanical power correlates with increased mortality in critically ill patients on invasive ventilation
- Frailty is associated with higher mortality and poorer neurological outcomes in patients with cardiac arrest
- Base excess shows 85.8% sensitivity and 82.9% specificity for neonatal sepsis diagnosis in meta-analysis
- Minimally invasive pulse wave analysis exceeds 30% error threshold for cardiac output and index
- CT-assessed sarcopenia combined with inflammatory markers predicts higher mortality in critically ill and COVID-19 patients
- Multimodal neuromuscular training reduces ACL injury risk and improves performance in adolescent volleyball players
- Elevated HMGB1 levels correlate with sepsis diagnosis and increased mortality risk in adult patients
- Branching-scenario games may improve equity in end-of-life care education through equity-by-design implementation
- Hypertension-frailty research surges after 2015, led by US, China, Italy in bibliometric analysis
- SLE patients have a 2- to 3-fold higher risk of intracerebral hemorrhage compared to non-SLE populations
- Deep learning pipeline detects vertebral fractures with 92.6% sensitivity and 95.8% specificity in older adults during routine CT scans
- Women critically ill adults on EEG have higher intracranial hemorrhage and seizure discharge rates than men
- AI dental reports match human readability but need standardized evaluation before routine clinical implementation
- Gut microbiota modulation offers insights for heat stroke prevention and treatment in clinical practice
- ECMO cannulation by intensivists shows 2% per cannula and 5% per patient complication rates in a meta-analysis of 12 studies
- Dengue vaccines lower viremia rates and hemorrhagic fever risk compared to placebo in a meta-analysis of 175434 participants
- Immunomodulatory therapies showed no mortality benefit or neurological harm in 2605 adults after cardiac arrest
- Initial intraosseous access shows no survival benefit over intravenous access in out-of-hospital cardiac arrest
- Neurostimulation therapies improve swallowing function in acutely ill patients with a standardized mean difference of -0.74
- Interleukin-7 therapy improves lymphocyte counts in sepsis and COVID-19 patients
- Carbon-plated shoes show minimal biomechanical impact in healthy adults
- ERAS protocols may reduce opioid use and shorten stays for patients undergoing orthognathic surgery
- Network meta-analysis ranks blood purification strategies for severe acute pancreatitis
- Ectopic thyroid carcinoma survival worsens with age over 50 years and chest or abdominal tumor location
- Ultrasound-facilitated catheter-directed alteplase reduces early recurrence in intermediate-risk pulmonary embolism
- Early Physical Interventions Reduce ICU-Acquired Weakness Risk
- High mortality rates observed in community-acquired pneumonia patients within intensive care units across low- and middle-income regions
- Evidence summary on glycemic variability management in ICU patients with cerebral infarction
- Scoping review maps burden of diabetic emergencies in African healthcare settings
- Meta-analysis of remimazolam versus propofol in mechanically ventilated ICU patients
- Secondary analysis of 342 sepsis patients reveals limited diagnostic utility for serum biomarkers in invasive candidiasis diagnosis
- Intraosseous route for out-of-hospital cardiac arrest linked to lower outcomes than intravenous access
- Case report details fatal rupture of a solitary fibrous tumor of the pleura in a trauma patient
- Conservative oxygen targets show no mortality difference in mechanically ventilated critically ill adults
- Endoscopic Guidance Does Not Reduce Complications in Tracheostomy
- Subprophylactic anti-Xa levels linked to higher venous thromboembolism risk in critically ill adults receiving low-molecular-weight heparin
- Case report and review highlights ultrasound-guided microwave ablation for metastatic breast cancer in a single patient
- Systematic Review of Injury Patterns in Ultimate Frisbee Athletes
- Early aggressive fluid resuscitation shows no difference in respiratory failure days in severe acute pancreatitis
- Sepsis survivors face high readmission, mortality, and long-term impairments
- Meta-analysis shows association between exclusive human milk and reduced mortality in gastroschisis
- Hospitalized children with HMPV infection had 28.0% severe CAP rates and higher risks of wheezing and co-infection
- POCUS and Laparoscopic Repair for Incarcerated Pediatric Direct Inguinal Hernia
- Hands-free carotid ultrasound improves ROSC detection in cardiac arrest
- Continuous glucose monitoring may reduce mortality and hypoglycemia in ICU patients compared to point of care testing
- Selective decontamination of the digestive tract reduces hospital mortality in mechanically ventilated ICU adults
- Pressure-controlled ventilation reduces peak airway pressure in scoliosis surgery
- Higher Intraoperative Mechanical Power Linked to Impaired Oxygenation and Pulmonary Complications After Orthopedic Surgery
- Hypophosphatemia during KRT linked to fewer ventilator-free days in critically ill patients
- Feasibility trial protocol for ultrasonography-guided therapeutic pleural drainage in ICU patients with pleural effusion and respiratory failure
- ICU CogHab cognitive rehabilitation feasibility study in ICU survivors with cognitive impairment
- Non-routine GRV monitoring does not increase feeding intolerance in ventilated adults
- Systematic review and meta-analysis of arterial catheter failure rates in adult critical care settings
- Systematic review and meta-analysis of procalcitonin diagnostic accuracy in community-acquired bacteraemia
- Meta-analysis finds dietary fibre reduces metabolic endotoxemia and inflammatory cytokines
- Large language models show varying accuracy for data extraction in sepsis guidelines
- Federated analytics platform deployment supports cross-border stroke research without reported clinical outcome data
- Umbrella review of 17 reviews on NTS assessment tools in healthcare settings
- Immediate coronary angiography does not alter 30-day mortality in OHCA survivors without ST elevation
- Systematic review of 68 articles shows systemic factors drive 51% of coal industry occupational accident risks
- Machine learning models for predicting emergency department outcomes and routing
- Conservative fluid management shows no difference in tissue perfusion or kidney injury in critically ill adults
- General Anesthesia Associated With Increased Severe Postpartum Hemorrhage Risk Compared to Neuraxial Anesthesia in Cesarean Deliveries
- Prospective observational study of inflammatory mediators in adult ED patients with suspected infection
- Case report reviews modified TCM use in recurrent gestational thrombocytopenia with improved platelet counts
- Low-use wrist-strap restraint strategy did not improve days free of delirium or coma compared with high-use strategy in mechanically ventilated adults
- Pilot study of fluoxetine and calcium in musculoskeletal trauma victims showed no measurable benefit
- Systematic review outlines EPI-DOM framework for assessing welfare in tilapia across laboratory and production systems
- Systematic review evaluates NLP models for triage accuracy against human triage in outpatient specialist referrals
- FirstCPR cluster randomised trial process evaluation finds leadership and champions drive community BLS uptake
- Corticosteroids reduce short-term and long-term mortality in adult sepsis patients according to a systematic review
- Simplified ventilator built from automotive parts delivered tidal volumes up to 600 mL in severe lung disease models
- Thiamin supplementation associated with reduced mortality in septic shock patients
- Higher plasma potassium levels associate with increased 30-day mortality in ED patients
- A 1-hour sepsis bundle is associated with reduced short-term mortality compared to non-bundle care in a meta-analysis of 4435 patients
- Immune dysregulation score predicts mortality and identifies hydrocortisone responders in community-acquired pneumonia
- Diaphragm ultrasound combined with D-RSBI predicts weaning outcomes in neurocritical patients on mechanical ventilation
- Neuropsychiatric documentation varies widely in adult ED patients with behavioral health complaints requiring clearance
- CytoSorb hemoadsorption shows no benefit and potential harm in small septic shock trial
- AI applications in acute care showed potential but face significant implementation challenges
- Mini-review examines MRSA-influenza co-infection pathogenesis and adjunctive therapies
- EMG provides diagnostic and therapeutic guidance for patients with cervical dystonia
- Retrospective study describes injury patterns and tetanus vaccination practices in Hangzhou trauma patients
- Mini-review examines operational definitions for precision perioperative AI applications
- Early supplemental parenteral nutrition may reduce ventilation time and ICU stay in older underfed ICU patients
- Meta-analysis identifies clinical signs associated with sepsis and mortality in young infants
- Neostigmine infusion in septic shock linked to lower TNF-alpha and 28-day mortality in single-center RCT
- Socioeconomic factors associated with increased mortality in adults with sepsis or septic shock
- Video call-assisted dispatcher guidance improves CPR quality metrics in simulation study of untrained students
- Nurse-led sedation protocols reduce mortality and delirium in mechanically ventilated ICU patients
- Early nutritional support nursing interventions reduce mechanical ventilation and hospital stay in critical cardiac surgery patients
- In adult ED encounters, clinician engagement with EHR-based SDOH data was rare but higher in opioid use disorder cases
- Prehospital point-of-care blood gas analysis associated with higher ambulatory treatment and admission rates in adult EMS patients
- Video laryngoscopes improve success rates and reduce dental compression compared with direct laryngoscopes in pediatric cardiac arrest simulations
- Multi-component environmental control intervention shows feasibility for sleep promotion in ventilated ICU patients
- Meta-analysis finds diaphragmatic atrophy and weakness in critically ill patients on ventilation or with sepsis
- Liposomal bupivacaine, nerve blocks compared to lidocaine for skin graft donor site pain in burn patients
- Supraglottic airway versus endotracheal intubation shows no overall survival benefit in out-of-hospital cardiac arrest
- PDCA Cycle Intervention Improves Critical Value Management Rate in Primary Healthcare Institutions
- Network meta-analysis finds PMX and HA 330 blood purification may reduce mortality in severe septic shock
- Testosterone gel fails to normalize serum levels in critically ill ICU patients in pilot RCT
- Remimazolam infusion associated with easier mask ventilation than propofol during anaesthesia induction
- Higher baseline chondroitin sulfate predicts greater mortality benefit from restrictive fluid strategy in sepsis
- VR and in-person sepsis simulation show similar skill outcomes in medical student pilot study
- Serum procalcitonin shows moderate accuracy for sepsis diagnosis in critically ill ICU patients
- NIRS-measured cerebral oxygen saturation predicts ROSC and neurological outcomes in adult cardiac arrest
- Inspiratory muscle training shows no clear effect on physical function in critically ill adults on mechanical ventilation
- Balanced salt solution in pediatric septic shock linked to lower AKI and RRT rates versus normal saline