Axia smartphone application increases ASAS20 response to 51% in patients with axial spondyloarthritis
Smartphone app improves quality of life for axial spondyloarthritis
This randomized controlled trial of 186 patients with axial spondyloarthritis found that the Axia app significantly improved BASDAI scores a…
A new smartphone app combining exercise and education helps patients with axial spondyloarthritis manage symptoms and improve daily function…
Specific muscle weaknesses following hip fractures correlate with persistent gait impairments and instability
Muscle Weakness Linked to Walking Problems After Hip Fractures
This narrative review synthesizes evidence regarding the relationship between post-hip fracture muscle atrophy and functional mobility in ol…
Specific muscle weaknesses after hip fractures are linked to walking difficulties and instability, highlighting the need for targeted rehabi…
Mapping Global Research Trends and Clinical Hotspots in Ulcerative Colitis and Depression
Ulcerative Colitis and Depression Research Surges
A comprehensive bibliometric analysis identifies key research trends and multidisciplinary approaches for managing patients with ulcerative …
Research on ulcerative colitis and depression is booming, with a focus on drug safety and quality of life.
161Tb-PSMA radioligand therapy achieves 83.9% disease control rate in metastatic castration-resistant prostate cancer
Radioligand Therapy Shows Promise for Metastatic Prostate Cancer
This meta-analysis of 6 studies involving 80 patients evaluates 161Tb-PSMA radioligand therapy for mCRPC. The analysis found a disease contr…
A new radioligand therapy shows a high disease control rate for patients with metastatic castration-resistant prostate cancer.
JAK inhibitors maintain efficacy in patients with multiple prior biologic DMARD failures
New Options Found for Difficult to Treat Rheumatoid Arthritis
This meta-analysis of 131 studies evaluates treatments for difficult-to-treat rheumatoid arthritis (D2T RA). The analysis found that Janus k…
Patients with difficult to treat rheumatoid arthritis may have more effective options when previous medications fail to control their sympto…
RA PRO dashboard shows no significant short-term effects on patient decision-making or medication adherence
New Dashboard Shows Limited Impact on Rheumatoid Arthritis Care
This stepped-wedge cluster randomized pragmatic trial evaluated the RA PRO dashboard in 554 patients with rheumatoid arthritis. The interven…
A new digital dashboard for tracking rheumatoid arthritis symptoms did not significantly improve patient decision making or medication adher…
Certolizumab pegol dose escalation from 200 mg to 400 mg results in 2-fold increase in plasma concentration
Trial shows dose changes impact drug levels in rheumatoid arthritis
This post hoc analysis of a Phase III trial and open-label extension evaluated certolizumab pegol pharmacokinetics in 982 patients with acti…
New analysis shows that changing the dosage of certolizumab pegol directly affects how much medicine stays in a patient's bloodstream.
Neuroimaging meta-analysis identifies specific structural and functional brain alterations in patients with systemic lupus erythematosus
Brain Imaging Reveals Specific Patterns in Lupus Patients
This meta-analysis of neuroimaging data evaluates structural and functional MRI findings in patients with systemic lupus erythematosus (SLE)…
New brain imaging analysis shows specific areas of activity and structure change in people with systemic lupus erythematosus.
P2X3 antagonists and multidisciplinary care offer a framework for managing cough hypersensitivity syndrome
New research identifies how the body triggers chronic cough
This narrative review explores the neuro-immune pathogenesis of cough hypersensitivity syndrome (CHS) involving P2X3 and TRP ion channels. T…
A new look at chronic cough shows how nerve signals and immune responses fail to turn off, potentially leading to better targeted treatments…
sFlt-1/PIGF ratio demonstrates superior diagnostic accuracy for preeclampsia compared to other serum biomarkers
Serum Biomarkers Show Promise for Detecting Preeclampsia
This meta-analysis of 22 studies involving 7,772 participants evaluated the diagnostic performance of various serum biomarkers for preeclamp…
A specific ratio of proteins in the blood may offer high accuracy in identifying preeclampsia during pregnancy, especially in the second tri…
Glucocorticoid use and rheumatoid arthritis significantly increase vertebral fracture risk in postmenopausal women
Several risk factors increase fracture risk for women with osteoporosis
This meta-analysis of 11 studies involving 7,605 participants identifies several risk factors for vertebral fractures in postmenopausal wome…
Women with rheumatoid arthritis or those using certain medications face a much higher risk of spine fractures.
TET2 functions as a tumor suppressor in myeloid malignancies and immunomodulator in solid tumors
TET2 protein acts as a key regulator in several diseases
This systematic review examines the role of TET2 across various conditions including hematological malignancies, solid tumors, and inflammat…
A key protein called TET2 helps control cell behavior and may play a major role in treating cancer and inflammatory conditions.
All Rheumatology Articles
- Axia smartphone application increases ASAS20 response to 51% in patients with axial spondyloarthritis
- Specific muscle weaknesses following hip fractures correlate with persistent gait impairments and instability
- Mapping Global Research Trends and Clinical Hotspots in Ulcerative Colitis and Depression
- 161Tb-PSMA radioligand therapy achieves 83.9% disease control rate in metastatic castration-resistant prostate cancer
- JAK inhibitors maintain efficacy in patients with multiple prior biologic DMARD failures
- RA PRO dashboard shows no significant short-term effects on patient decision-making or medication adherence
- Certolizumab pegol dose escalation from 200 mg to 400 mg results in 2-fold increase in plasma concentration
- P2X3 antagonists and multidisciplinary care offer a framework for managing cough hypersensitivity syndrome
- Neuroimaging meta-analysis identifies specific structural and functional brain alterations in patients with systemic lupus erythematosus
- sFlt-1/PIGF ratio demonstrates superior diagnostic accuracy for preeclampsia compared to other serum biomarkers
- Glucocorticoid use and rheumatoid arthritis significantly increase vertebral fracture risk in postmenopausal women
- TET2 functions as a tumor suppressor in myeloid malignancies and immunomodulator in solid tumors
- Tacrolimus significantly reduces urine protein compared to MMF, placebo, and intravenous cyclophosphamide
- Black and Indigenous patients are under-represented in recent randomized controlled trials for systemic lupus erythematosus
- Multidisciplinary teams and bloodless medicine pathways may improve outcomes for acute gastrointestinal bleeding
- Evaluating Biological DMARD Discontinuation versus Dose Reduction in Rheumatoid Arthritis Remission
- Anifrolumab shows higher odds for BICLA response compared to belimumab in systemic lupus erythematosus
- JAK inhibitors show 81.7% treatment retention in adult patients with rheumatoid arthritis and interstitial lung disease
- MSC therapy improves salivary flow in Sjögren's animal models, meta-analysis finds
- Minimally invasive fixation of thoracolumbar fractures in ankylosing spondylitis reduces operative time and blood loss
- Crohn disease and ulcerative colitis causally raise ankylosing spondylitis risk
- AML infiltration of bile duct identified as primary cause of acute pancreatitis in case report
- Medicinal and edible plants offer potential immunomodulatory mechanisms for various autoimmune diseases
- Intermittent and dynamic NPWT modes may offer advantages over continuous mode for wound healing outcomes
- Digital multi-domain intervention aims to prevent disability in older adults
- R-(+)-propranolol targets SOX18 for anti-hemangioma effect independent of beta-blockade
- Academic partnerships for family medicine education promote contextually grounded curricula and faculty development pathways
- Consistent monitoring principles exist for patients with familial Mediterranean fever across 42 publications
- FLASH radiotherapy transitions from experimental physics toward clinical precision and proton therapy workflows
- Exercise programs improve muscle mass and physical performance indicators in patients with liver cirrhosis
- Electroacupuncture ranks highest for total efficacy in acupuncture interventions for polycystic ovary syndrome
- Sarcopenia linked to 2.16-fold higher odds of atrial fibrillation in meta-analysis
- Symptom-informed updates increase predicted probabilities of hEDS and POTS in comorbid patients
- Higher AMH levels in PCOS patients correlate with higher oocyte yields and increased OHSS risk
- AI-assisted clinicians achieve 1.000 sensitivity in melanoma diagnosis but autonomous AI lacks clear clinical advantage
- Bibliometric analysis reveals expanding multidisciplinary research landscape for diabetes-related hearing loss
- ME/CFS linked to 7-fold higher odds of irritable bowel syndrome in meta-analysis
- AI models provide high accuracy for pulmonary inflammation and COVID-19 detection in diverse populations
- Predictive models for postoperative infection risk in hip fractures show AUC of 0.699 to 0.946
- Acupuncture effectively relieves pain and improves function in chronic low back pain, new guideline states
- Endoscopic closure of congenital bronchoesophageal fistula resolves cough in adult case
- Pyrotinib-based regimen achieves pathological complete response after non-response to standard neoadjuvant therapy in HER2+ breast cancer
- Upadacitinib shows rapid improvement in refractory acrodermatitis continua of Hallopeau
- FGF/FGFR signaling systems provide diverse mechanistic targets across multiple systemic autoimmune rheumatic diseases
- Essential oil interventions reduce acute nausea severity in patients with chemotherapy-induced breast cancer symptoms
- Network meta-analysis protocol aims to rank structured exercise interventions for fall prevention in dementia
- A staged framework integrates dry needling, Fascial Manipulation, and Yijinjing for chronic cervical myofascial pain
- Airway clearance techniques triple odds of treatment success in Chinese pneumonia patients
- Mongolian warm acupuncture improves clinical response in knee osteoarthritis vs oral meds
- Type 2 monoclonal antibodies reduce annual moderate-to-severe exacerbations in patients with eosinophilic COPD
- GNPTAB gene mutations characterize clinical phenotypes and skeletal deformities in Chinese mucolipidosis type II alpha/beta patients
- Tegileridine 0.5 mg reduces fentanyl-induced cough incidence from 28.7% to 11.1%
- Subcutaneous methotrexate improves ACR20 response and reduces GI side effects in RA
- Proposed methodology for developing a Core Outcome Set to standardize Traditional Chinese Medicine trials for pharyngitis
- Dual-channel supraglottic airways may shorten insertion time and reduce hypoxemia during upper gastrointestinal procedures
- IEN plus NACT shows greatest improvement in CD4+ counts among ranked strategies
- Elevated serum M2BPGi is associated with a 4.61 hazard ratio for hepatocellular carcinoma development
- Short-course antibiotic therapy yields comparable clinical and bacteriological success for adults with community-acquired pneumonia
- Opsin 3 serves as a potential therapeutic target for melanoma and inflammatory skin diseases
- Combination therapies with adalimumab, infliximab, tofacitinib, or upadacitinib increase serious infection risk in rheumatoid arthritis
- Integrated simulation-based training models provide a framework for perioperative point-of-care ultrasound competency
- Extracellular vesicles offer immunomodulatory mechanisms and targeted delivery for potential precision therapies in rheumatoid arthritis
- Comprehensive clinical reference system integrates etiology, diagnosis, and management for chronic pancreatitis complications
- EMG biofeedback assisted pelvic floor training improves muscle strength and reduces incontinence severity
- Gut microbiota dysbiosis linked to osteoarthritis pathology in preclinical and human studies
- Intestinal subepithelial myofibroblasts drive mucosal repair and pathological fibrosis in Inflammatory Bowel Disease
- FDA Approves Xeljanz XR (tofacitinib) for Multiple Inflammatory Conditions
- FDA Approves Xeljanz (tofacitinib) for Multiple Inflammatory Conditions
- FDA Approves Xeljanz (tofacitinib) for Pediatric Psoriatic Arthritis and Juvenile Idiopathic Arthritis
- Nafamostat mesylate reduces bleeding risk compared to citrate for anticoagulation during continuous renal replacement therapy
- Evaluating Treat to Target Outcomes in Elderly and Young Rheumatoid Arthritis Patients
- Belimumab linked to higher remission and low disease activity rates in SLE without glucocorticoids
- Upadacitinib 15 mg daily achieves DAS28-CRP ≤3.2 in 43.3% of patients versus 22.4% for adalimumab
- Deucravacitinib modulates up to 2529 genes and SLE-relevant gene sets including interferon-regulated genes
- Belimumab plus standard therapy shows numerically greater reductions in IgA, IgM, and anti-dsDNA antibodies
- Spontaneous splenic rupture occurs as a rare but life-threatening complication in enteric fever infections
- Higher Triglyceride-Glucose index is associated with increased risk of albuminuria in chronic kidney disease
- Tai Chi and Wuqinxi reduce pain while Pilates and Baduanjin improve physical function in knee osteoarthritis
- Peer support may impact fear of disease progression and psychological symptoms in patients with glioma
- Corticosteroid and cyclophosphamide exposure are associated with higher mortality in Middle Eastern and North African SLE
- Hand-dominant joint involvement patterns associate with better clinical outcomes in early rheumatoid arthritis
- Anti-DFS70 antibodies show high specificity but low sensitivity for excluding Systemic Lupus Erythematosus
- Aerobic and resistance exercise improve fatigue, physical function, and pain in systemic lupus erythematosus
- Intervention Mapping framework supports development of tailored behavioral interventions for stroke survivor rehabilitation
- Dipyridamole combined with immunoglobulin and aspirin improves clinical efficacy in children with Kawasaki disease
- Dupilumab as an off-label adjunctive approach facilitates corticosteroid minimization in severe pemphigus vulgaris
- Evaluating the Efficacy of Traditional Chinese Medicine Decoctions for Rheumatoid Arthritis Management
- Peripheral mechanisms like proton-sensing channels and neurovascular remodeling contribute to pain in osteoarthritis
- AI-driven in silico tools enhance sequence design and optimization for monoclonal antibody development
- Superficial heat therapy provides analgesic efficacy for dysmenorrhoea, endometriosis pain, and labor discomfort
- Elevated SII is significantly associated with increased COPD risk, all-cause mortality, and respiratory failure
- Aortic valve opening status best predicts VA-ECMO weaning success in cardiogenic shock
- FDA Approves Prolia (denosumab) for Osteoporosis and Bone Loss in Multiple Settings
- Extreme temperature exposure may worsen COPD outcomes in Chinese populations, protocol outlines
- JAK and IL-6 inhibitors outperform TNF inhibitors for activity limitation in rheumatoid arthritis
- Strengthening-based rehabilitation improves knee muscle strength following ACL reconstruction but shows no effect on hop performance
- Atypical granular cell tumor requires immunohistochemical detection and multimodal imaging to avoid common misdiagnosis as schwannoma
- TCM influenza research surges after 2020, shifting from clinical practice to mechanistic studies
- Sulbactam-durlobactam and tigecycline provide clinical improvement for polymicrobial infections in severe acute pancreatitis
- Six paradigm shifts reframe preeclampsia as a first-trimester villous trophoblast syndrome
- Combination therapies of plant-derived compounds outperform monotherapy for psoriasis vulgaris with specific immunological profiles
- CAR-T cell therapy for lymphoid malignancies presents a biphasic pattern of infectious complications
- EMG-based bioelectrical feedback improves Fugl-Meyer scores by 9.50 points in post-stroke hemiplegia
- Continuous renal replacement therapy may support metabolic and circulatory stability in preterm infants with AKI
- Avacopan is associated with high remission rates and low relapse in ANCA-associated vasculitis
- Bio-inductive collagen scaffolds improve structural integrity but show inconsistent translation to patient-perceived gains
- Tebentafusp provides modest survival benefit and manageable safety profile in metastatic uveal melanoma
- Enteral immunonutrition reduces infectious complications and hospital stay duration in gastric cancer surgery
- Multidisciplinary competency framework for outpatient dental sedation and anesthesia nurses improves perioperative safety
- ACLF-specific prediction models show better discrimination than general models for mortality risk assessment
- Naive pooling of RCTs and non-randomized studies in network meta-analyses is common and problematic
- Long-term personalized exercise therapy shows potential cost-effectiveness for patients with axial spondyloarthritis
- EmiratesMEDs competency framework establishes 9 thematic roles and 14 EPAs for UAE medical education
- Esketamine significantly reduces postoperative anxiety (SMD -1.23) and depressive symptoms (SMD -0.92) in adult patients
- Machine learning and postoperative indicators improve AUC for predicting anastomotic leak in gastric cancer surgery
- Structured physical activity improves FEV1% predicted by 5.79 and PAQLQ scores in patients with asthma
- Structured exercise improves 6-minute walk distance by 38.62 m in idiopathic pulmonary fibrosis
- Dapirolizumab pegol increases BICLA response rate by 14.6% over placebo in moderate-to-severe SLE
- Sepsis Mortality Prediction Models Show Moderate Performance
- Large language models provide automated feedback to improve diagnostic accuracy and report quality in radiology training
- Research in coronary heart disease shows misalignment between investment and clinical guideline priorities
- IoT-assisted pulmonary rehabilitation protocol for moderate-to-severe stable COPD patients in single institution
- Prediction models show moderate discrimination for ARDS occurrence and mortality in sepsis patients
- Nursing process-oriented bundled interventions and digital monitoring may improve surgical site infection prevention
- Video observed therapy improves treatment success and adherence in adults with tuberculosis
- Meropenem and norepinephrine managed a case of chorioamnionitis and septicemia involving Hafnia alvei
- Diverse exercise modalities mitigate systemic and local inflammation in older adults with sarcopenia
- Lower HDL, higher LDL, TG, TC linked to preeclampsia risk in meta-analysis
- Systemic immune-inflammation index and systemic inflammation response index correlate with disease activity in systemic lupus erythematosus
- Twelve-month follow-up shows no signs of recurrence in a 56-year-old male with follicular thyroid carcinoma treated with radioactive iodine
- Adrenal insufficiency is first manifestation in 73.6% of APS patients with adrenal involvement
- Narrowband UVB remains first-line phototherapy for vitiligo, with JAK inhibitors emerging as adjuncts
- Semaglutide use may be associated with kidney damage in 20 cases across 18 studies
- Short-term prednisolone bridging enables 95% discontinuation in new rheumatoid arthritis patients after 24 months
- Higher preoperative NLR and SII show increased risk for postoperative pneumonia and pulmonary complications in lung and esophageal surgery
- Sarcopenia prediction models in China show variable discriminative ability and limited clinical applicability
- PMASD risk models show AUC 0.812 to 0.914 but high bias limits clinical use
- NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia
- Meta-analysis finds rheumatoid arthritis associated with increased thyroid cancer risk in pooled cohort data
- SLE linked to 53% higher odds of cognitive impairment in meta-analysis of 7 million
- ICU nurses in China report femoral vein as the preferred site for temporary hemodialysis catheter removal
- Systematic review shows intralesional vitamin D reduces steroid risks for keloid patients
- AI-driven cardiovascular risk prediction in type 2 diabetes shows promise but bias and lack of diversity limit clinical use
- Combination voriconazole and micafungin improved a boy with CGD and invasive Aspergillus lentulus infection
- Subcutaneous anifrolumab improves BICLA response by 15.5% in moderate to severe SLE
- Tubulointerstitial inflammation and fibrosis predict renal function decline in adult lupus nephritis patients across multiple studies
- Microbiota-targeted interventions for elderly-onset rheumatoid arthritis remain an area requiring further investigation
- Chromoblastomycosis diagnosis is often delayed in immunocompromised patients with atypical clinical manifestations
- Integrated care combining antiangiogenic bridging and ischemia-directed therapies supports long-term success in neovascular glaucoma management
- Network meta-analysis of exercise interventions for COPD rehabilitation
- FDA Approves Tofidence (tocilizumab-bavi) for Multiple Inflammatory Conditions and COVID-19
- Systematic review and meta-analysis of machine learning models for deep vein thrombosis prediction in hospitalized adults
- Systematic review and meta-analysis shows death education improves end-of-life care competence in nurses
- Narrative review of AI and simulation in medical education for student-centered learning
- Case report of cefotaxime treatment for peritoneal dialysis-related peritonitis in an elderly patient
- Case Report and Review of Recurrent Dysplasia Epiphysealis Hemimelica After Surgery
- FDA Approves Rinvoq Lq (upadacitinib) for Polyarticular Juvenile Idiopathic Arthritis
- FDA Approves Tyenne (tocilizumab-aazg) for Multiple Inflammatory Conditions
- FDA Approves Tyenne (tocilizumab-aazg) for Multiple Indications Including RA and COVID-19
- Systematic review and meta-analysis of Wuqinxi for knee osteoarthritis joint function
- Meta-analysis finds hydroxychloroquine does not reduce most pregnancy complications in SLE
- Core set domains capture SLE treatment response in 89.5% of cases at week 52
- Systematic review of acupuncture for sepsis-associated acute gastrointestinal injury
- Umbrella review suggests curcumin may offer comparable efficacy and better tolerability than NSAIDs for osteoarthritis
- Four weekly text messages for 6 months showed modest CVD risk factor improvements in Swedish hypertension patients
- Meta-analysis finds modest PTS reduction with compression stockings after DVT
- Narrative review of short geriatric screening tools in acute care settings
- Meta-analysis of video double-lumen tubes shows trend toward shorter intubation time in thoracic surgery
- Narrative review on non-infectious uveitis and scleritis treatment gaps
- Guideline summarizes evidence on nebulization management for nasal high-flow oxygen therapy
- Case report on acupuncture for diminished ovarian reserve and recurrent IVF failure
- Network meta-analysis of nurse-implementable sedation strategies in mechanically ventilated adults
- Case report on ribbon sign in NIID diagnosis with coincidental intracranial stenosis
- Meta-analysis shows VR reduces pain in adult ICU patients receiving conventional care
- Case report of high-dose ceftazidime in an 84-year-old man with skull base osteomyelitis and type 1 diabetes
- Narrative review offers practical guidance for diagnosing and managing emergency rheumatic disease in children
- Review of 16 cases shows 25% mortality for pulmonary mucormycosis in DKA patients treated with amphotericin B
- Systematic Review of Schisandra chinensis for Metabolic Dysfunction-Associated Steatotic Liver Disease
- Case report and literature review on IgG4-related disease misdiagnosed as pancreatic cancer in a 70-year-old male
- Meta-analysis of ROP treatments finds anti-VEGF linked to less myopia than laser or surgery
- Narrative review explores mitochondrial-targeted therapeutics for oral squamous cell carcinoma
- Enpatoran fails to show dose-response in moderate-to-severe SLE phase 2 trial
- Review of rectal abscess case after endoscopic mucosal resection highlights diagnostic considerations
- Narrative review explores m6A modification and metabolic reprogramming in rheumatoid arthritis
- Meta-analysis shows AI virtual patient simulations improve psychiatric interview training in health professions education
- Review of SC-EVs for SLE and MS highlights immunomodulatory mechanisms and neuroprotective potential
- Narrative review suggests MRgFUS reduces lesion size and symptoms in women with adenomyosis
- Global research on olfactory dysfunction mechanisms shows rising publication trends and key molecular pathways
- Narrative review suggests suprachoroidal injections may improve vision and reduce edema in diabetic macular edema
- Case report describes rare coexistence of giant cell tumor and enchondroma in a 36-year-old woman
- Network meta-analysis of immunomodulatory therapies for sepsis mortality
- Narrative review on multi-omics for spondyloarthritis and psoriatic arthritis
- Systematic review and meta-analysis shows remimazolam versus non-remimazolam anesthesia and delirium risk
- Systematic review and meta-analysis of vismodegib for periocular and orbital basal cell carcinoma
- Scoping review maps educational strategies for clinical medical students in laboratory medicine
- Systematic Review Finds Intersectional Barriers Hinder Nursing Education Access
- Systematic review and meta-analysis of herpes zoster risk in rheumatoid arthritis patients
- Vunakizumab improves ASAS20 response in active radiographic axial spondyloarthritis at 16 weeks
- SLE-DAS Responder Index shows 34% response rate in systemic lupus erythematosus trials
- Review of five language models for rheumatology case evaluation with and without retrieval augmentation