Ketamine is associated with seizure reduction in refractory and super-refractory status epilepticus
Ketamine Shows Potential for Managing Refractory Status Epilepticus
This systematic review of 491 patients with RSE and SRSE indicates that ketamine-containing regimens are associated with clinically relevant…
Ketamine may help stop seizures in patients with severe, drug-resistant epilepsy, with some evidence showing high rates of seizure resolutio…
Higher baseline Prognostic Nutritional Index reduces mortality risk in sepsis and pneumonia patients
Nutritional status helps predict survival in patients with severe infections
This meta-analysis of 28,757 patients with infectious diseases found that higher baseline Prognostic Nutritional Index (PNI) is associated w…
A high nutritional score at the start of treatment can help doctors identify which patients with sepsis or pneumonia are at the highest risk…
Early mobilization reduces ICU-acquired weakness and delirium in patients with acute respiratory distress syndrome
Early Movement Helps ARDS Patients in Intensive Care
This meta-analysis of 7 RCTs indicates that early mobilization in patients with acute respiratory distress syndrome (ARDS) reduces the incid…
Starting movement early in intensive care may cut weakness and confusion for ARDS patients. It also shortens time on a breathing machine.
Multi-omics biomarkers and AI integration offer potential for precision medicine in rheumatoid arthritis
New biomarkers could help personalize treatment for rheumatoid arthritis
This systematic review evaluates multi-omics biomarkers, including TAOK3 and S-adenosylmethionine, for use in rheumatoid arthritis. The find…
New markers like TAOK3 and S-adenosylmethionine could help doctors predict how patients with rheumatoid arthritis will respond to treatment.
Sacituzumab govitecan significantly improves progression-free survival and overall survival in metastatic breast cancer
Sacituzumab Govitecan Shows Improved Survival for Metastatic Breast Cancer
This meta-analysis of 1,900 patients with metastatic breast cancer found that sacituzumab govitecan significantly prolonged progression-free…
Sacituzumab govitecan may improve survival and progression-free time for patients with metastatic breast cancer compared to standard chemoth…
Twin tubal pregnancy may present with disproportionately elevated serum β-hCG and no uterine sac
Twin Ectopic Pregnancy Identified in Rare Case Report
This case report and literature review describes a 40-year-old woman with a unilateral twin tubal pregnancy. The report highlights the impor…
A rare case of a twin ectopic pregnancy was identified when a patient showed high hormone levels and no gestational sac in the uterus.
Isolated gastric Kaposi sarcoma occurs following allogeneic hematopoietic stem cell transplantation in rare cases
Rare Gastric Kaposi Sarcoma Found After Stem Cell Transplant
This case report and literature review identifies 20 cases of Kaposi sarcoma following allogeneic hematopoietic stem cell transplantation. T…
A rare case of stomach cancer linked to stem cell transplants highlights the need for early testing when patients have new digestive symptom…
Liposomal bupivacaine shows statistically significant reduction in pain scores on POD2 for orthopedic surgery
Liposomal Bupivacaine Shows Limited Difference in Orthopedic Surgery Pain
This meta-analysis of 3,389 patients undergoing open orthopedic surgery found that liposomal bupivacaine significantly reduced pain scores o…
New analysis of 3,389 patients shows liposomal bupivacaine may slightly reduce pain on day two of surgery but does not lower opioid use.
Psychological and behavioral interventions significantly reduce depression severity in people with epilepsy
Behavioral Therapies May Help Reduce Depression in People with Epilepsy
This meta-analysis evaluates the efficacy of psychological and behavioral interventions for depression in patients with epilepsy. The analys…
Psychological and behavioral therapies, such as cognitive behavioral therapy, show promise in reducing depression symptoms for people living…
Omadacycline and baloxavir marboxil used in an 89-year-old with influenza A, psittacosis, and Klebsiella pneumonia
New drug combination helps elderly man with severe lung infections
This case report describes an 89-year-old man with influenza A, Chlamydia psittaci pneumonia, and Klebsiella pneumoniae who improved and was…
A combination of omadacycline and baloxavir marboxil helped an 89-year-old man recover from a complex, multi-organ infection in the ICU.
Amniotic membrane transplantation and excision may treat occupationally acquired conjunctival melanosis after exposure cessation
Removing tissue and transplanting membrane helps treat eye discoloration
This case report and review of literature examines a 40-year-old male with conjunctival melanosis following exposure to phenylenediamine. Th…
A man with dark spots on his eye from chemical exposure saw significant improvement after a surgical procedure and avoiding the chemicals.
Ivarmacitinib shows significant clinical improvement in a patient with alopecia areata and systemic lupus erythematosus
Ivarmacitinib Shows Promise for Alopecia Areata and Lupus Hair Loss
This case report and literature review describes a 35-year-old woman with severe patchy alopecia and systemic lupus erythematosus who showed…
A new treatment may help patients with overlapping hair loss conditions like alopecia areata and systemic lupus erythematosus.
All Rheumatology Articles
- Early mobilization reduces ICU-acquired weakness and delirium in patients with acute respiratory distress syndrome
- Ketamine is associated with seizure reduction in refractory and super-refractory status epilepticus
- Higher baseline Prognostic Nutritional Index reduces mortality risk in sepsis and pneumonia patients
- Multi-omics biomarkers and AI integration offer potential for precision medicine in rheumatoid arthritis
- Sacituzumab govitecan significantly improves progression-free survival and overall survival in metastatic breast cancer
- Twin tubal pregnancy may present with disproportionately elevated serum β-hCG and no uterine sac
- Isolated gastric Kaposi sarcoma occurs following allogeneic hematopoietic stem cell transplantation in rare cases
- Liposomal bupivacaine shows statistically significant reduction in pain scores on POD2 for orthopedic surgery
- Psychological and behavioral interventions significantly reduce depression severity in people with epilepsy
- Omadacycline and baloxavir marboxil used in an 89-year-old with influenza A, psittacosis, and Klebsiella pneumonia
- Amniotic membrane transplantation and excision may treat occupationally acquired conjunctival melanosis after exposure cessation
- Ivarmacitinib shows significant clinical improvement in a patient with alopecia areata and systemic lupus erythematosus
- Mediastinal schwannoma with cystic changes mimics malignancy on PET, EBUS-TBNA non-diagnostic
- Nurse-coordinated monitoring of biomarkers and symptoms supports clinical assessment for immune checkpoint inhibitor safety
- Rapid integrated molecular testing shows high diagnostic accuracy for influenza, RSV, and SARS-CoV-2
- Generative AI in medical education poses risks of deskilling and automation bias in clinical training
- Vonoprazan reduces delayed bleeding risk in patients with gastric post-endoscopic submucosal dissection ulcers
- High abdominal aortic calcification index predicts poorer cardiovascular event-free survival in patients with chronic kidney disease
- Mentefact-based algorithmic framework improves conceptual alignment in health sciences education systematic reviews
- Rare cardiac epithelioid hemangioendothelioma demands thorough imaging and pathology workup
- Antisynthetase syndrome can mimic cellulitis, with skin, muscle, and lung improvement on immunosuppression
- Endoscopic full-thickness resection resolves abdominal pain in a patient with a gastric diverticulum
- High-flow nasal cannula shows no significant difference from noninvasive ventilation in acute heart failure
- Delayed margin formation in lung tumor microwave ablation may occur despite lack of immediate intraprocedural margin
- Volumetric inaccuracies in nasopharyngeal carcinoma primary tumor segmentation may reduce tumor control probability
- Bronchoscopic resection and individualized therapy may treat tracheobronchial tuberculosis presenting as endobronchial masses
- Prediction models for post-induction hypotension show a pooled AUC of 0.81 in 17 studies
- FDA Approves Avtozma (tocilizumab-anoh) for Multiple Inflammatory Conditions
- FDA Approves Avtozma (tocilizumab-anoh) for Multiple Inflammatory Conditions
- Prolonged SEMS retention for refractory variceal bleeding allows removal after 387 days
- Deep learning models show high sensitivity and specificity for SLE and lupus nephritis diagnosis
- Specific traditional Chinese medicine formulations show varied outcomes in patients with ischemic stroke
- Complete hydatidiform mole with normal fetus in twin gestation after embryo transfer: case report
- Unilateral biportal endoscopic decompression and pulsed radiofrequency neuromodulation may address symptomatic lumbar spinal stenosis
- Immune signaling and bidirectional neuropeptide release drive nociceptor sensitization in osteoarthritis pain
- AI-enabled language technologies support dental student communication training despite sparse evidence of clinical outcomes
- No direct evidence exists regarding altered ncRNA levels in breast milk from mothers with SLE
- 2023 ACR/EULAR APS criteria show 0.99 specificity but lower sensitivity in obstetric phenotypes
- Structured palliative care and virtue-based competencies mitigate moral distress in Brazilian intensive care units
- Wuqinxi exercise reduces systolic and diastolic blood pressure in adults with primary hypertension
- Voclosporin doubles proteinuria reduction in lupus nephritis but raises adverse events
- ACR20 overestimates treatment effects compared to target-based outcomes in patients with rheumatoid arthritis
- Exercise improves physical function and reduces pain in adults with rheumatoid arthritis
- Moderate-dose early mobilization reduces ICU length of stay by 4.14 days in ventilated patients
- Antibiotics and supportive care effectively treat 2 cases of emphysematous cystitis
- Eighteen assessment tools exist for identifying and managing stroke-related sarcopenia in clinical practice
- Targeted therapy plus dexamethasone resolves S. suis meningitis without surgery in case report
- CDAI and SDAI scores improve prediction of osteoporosis in patients with rheumatoid arthritis
- Fibrosis-informed markers provide a decision architecture for statin allocation in intermediate-risk MASLD patients
- Fetoscopic band release is technically feasible for managing pseudoamniotic band syndrome in twin pregnancies
- Metabolic risk factors including diabetes and metabolic syndrome are associated with increased hepatocellular carcinoma risk
- Multiple concurrent factors including cyst, constriction, and iatrogenic injury can cause radial nerve palsy
- Long-term surveillance and endoscopic screening are critical for patients with synchronous multifocal early gastric cancer
- Obinutuzumab improves SRI-4 response by 23.1 percentage points in active systemic lupus erythematosus
- FDA Approves Benlysta (belimumab) for Active Lupus Nephritis and SLE
- FDA Approves Benlysta (belimumab) for Pediatric and Adult Lupus Nephritis
- Radiofrequency ablation shows lower postoperative pain and paresthesia risk compared to endovenous laser ablation
- Acupuncture combined with manipulation significantly improves clinical effectiveness and function in lateral epicondylitis
- AI, machine learning, and deep learning models facilitate multimodal diagnosis and prognosis in MASLD
- Digital intelligence integrates advanced technologies and diverse educational objectives into dental technology curriculum reform
- Electrosurgical snare combined with laser ablation effectively treats bronchial myelolipoma in a case series
- Star fruit-infused liquor consumption can cause secondary oxalate nephropathy and acute kidney injury
- Low preoperative AGR tied to worse survival in bladder cancer, meta-analysis finds
- Yoga and Baduanjin improve lung function while Tai Chi improves quality of life in COPD
- Indigenous self-determination in governance and cultural safety are critical for Aboriginal general practice pipelines
- Tailor-made DMARD selection based on autoantibody status does not improve DAS scores in RA
- Uni-port video-assisted thoracoscopic surgery with vascular pre-blocking successfully manages large pulmonary arteriovenous malformations
- Pharmacist-led medication therapy management improves adherence and glycemic control in a patient with complex T2DM
- Balanced crystalloid solutions reduce mortality and acute kidney injury in adult patients with sepsis
- AI assisted training improves surgical and invasive procedural skills compared to traditional learning paths
- Clinical Segmentation Evaluation Scale shows strong correlation with IoU for AI nerve segmentation
- Staged traditional Chinese medicine treatment resulted in lesion reduction for a pulmonary inflammatory pseudotumor
- Pharmacist-integrated collaborative outpatient care reduces systolic blood pressure by 7.11 mm Hg in CKM populations
- Machine learning models show high predictive AUC for postpartum stress urinary incontinence
- Frailty prevalence in peritoneal dialysis patients varies from 7.3% to 83% across included studies
- Adalimumab improves axial inflammation in hidradenitis suppurativa with spondyloarthritis features
- Tofacitinib reduces joint swelling in PAPA syndrome but does not reverse structural damage
- Multimodal framework using Lp(a), hs-CRP, and colchicine addresses residual risk in Chinese CAD patients
- System-level reforms and standardized systems improve efficiency in medical device and pharmaceutical clinical trial initiation
- Self-administered acupressure and hypnosis show no group-level effects on blood pressure in hypertension
- Early Full Enteral Feeding Cuts Preterm Hospital Stay
- Reduced-dose daratumumab and bortezomib may achieve partial renal remission in CyBorD-refractory PGNMID
- ChatGPT 5.4 demonstrates high agreement with expert consensus on hemodialysis indications in exploratory study
- Smoking exposure dominates literature on autoimmune inflammatory rheumatic diseases with limited immune-mechanism integration
- Lifestyle modification and optimized proton pump inhibitor therapy are first-line treatments for gastroesophageal reflux disease
- Mucocutaneous manifestations serve as diagnostic indicators for various systemic diseases and paraneoplastic syndromes
- Avacopan Demonstrates Non-Inferiority to Prednisone Taper in Granulomatosis with Polyangiitis and Microscopic Polyangiitis
- Mechanical loading induces innate immune reprogramming and mitochondrial danger signals in osteoarthritis models
- Expedited transfer does not reduce mortality in out-of-hospital cardiac arrest
- Structured education programs reduce HbA1c and multiple cardiometabolic risk factors in Type 2 Diabetes
- FDA Approves Krystexxa (pegloticase) for Chronic Gout Refractory to Conventional Therapy
- FDA Approves Saphnelo (anifrolumab) for Moderate to Severe Systemic Lupus Erythematosus
- Meta-analysis identifies 101 genetic risk loci including 12 novel sites for systemic lupus erythematosus
- Photobiomodulation protocol aims to consolidate preclinical evidence for ophthalmic diseases
- Preoperative exercise-based prehabilitation reduces postoperative pulmonary complications and hospital stay after lung cancer surgery
- Circulating galectin-3 levels are significantly higher in patients with systemic lupus erythematosus
- Intraoperative intravenous methadone reduces 24-h pain intensity and opioid consumption after cardiac surgery
- Pulmonary TB History Linked to Higher COPD Odds
- Chinese medicine external therapies show varying efficacy for symptoms in diarrhea-predominant irritable bowel syndrome
- Psoriasis patients with moderate to severe disease show higher prevalence of type 2 diabetes
- Individualized blood pressure management reduces delirium but does not impact acute kidney injury or mortality
- Ofloxacin shows superior relative efficacy for pain control after photorefractive keratectomy
- Obstructive sleep apnea syndrome is associated with significantly higher blood pressure variability in patients
- Integrated TCM and Western medicine increases pregnancy rate and ovulation rates in PCOS-related infertility
- Most children with congenital myopathies maintain preserved intellectual functioning despite varying neuropsychological profiles
- Glucocorticoid signaling and stress-related neuroendocrine dysregulation influence intraocular pressure and inflammatory pathways in ocular diseases
- Viral mimicry induction via epigenetic therapies and DNA damage may convert cold tumors to hot
- FDA Approves Bonsity (teriparatide) for Osteoporosis Treatment
- FDA Approves Forteo (teriparatide) for Osteoporosis Treatment
- FDA Approves Tymlos (abaloparatide) for Osteoporosis in Postmenopausal Women and Men
- Axia smartphone application increases ASAS20 response to 51% in patients with axial spondyloarthritis
- Specific muscle weaknesses following hip fractures correlate with persistent gait impairments and instability
- Mapping Global Research Trends and Clinical Hotspots in Ulcerative Colitis and Depression
- 161Tb-PSMA radioligand therapy achieves 83.9% disease control rate in metastatic castration-resistant prostate cancer
- JAK inhibitors maintain efficacy in patients with multiple prior biologic DMARD failures
- RA PRO dashboard shows no significant short-term effects on patient decision-making or medication adherence
- Certolizumab pegol dose escalation from 200 mg to 400 mg results in 2-fold increase in plasma concentration
- P2X3 antagonists and multidisciplinary care offer a framework for managing cough hypersensitivity syndrome
- Neuroimaging meta-analysis identifies specific structural and functional brain alterations in patients with systemic lupus erythematosus
- sFlt-1/PIGF ratio demonstrates superior diagnostic accuracy for preeclampsia compared to other serum biomarkers
- Glucocorticoid use and rheumatoid arthritis significantly increase vertebral fracture risk in postmenopausal women
- TET2 functions as a tumor suppressor in myeloid malignancies and immunomodulator in solid tumors
- Tacrolimus significantly reduces urine protein compared to MMF, placebo, and intravenous cyclophosphamide
- Black and Indigenous patients are under-represented in recent randomized controlled trials for systemic lupus erythematosus
- Multidisciplinary teams and bloodless medicine pathways may improve outcomes for acute gastrointestinal bleeding
- Evaluating Biological DMARD Discontinuation versus Dose Reduction in Rheumatoid Arthritis Remission
- Anifrolumab shows higher odds for BICLA response compared to belimumab in systemic lupus erythematosus
- JAK inhibitors show 81.7% treatment retention in adult patients with rheumatoid arthritis and interstitial lung disease
- MSC therapy improves salivary flow in Sjögren's animal models, meta-analysis finds
- Minimally invasive fixation of thoracolumbar fractures in ankylosing spondylitis reduces operative time and blood loss
- Crohn disease and ulcerative colitis causally raise ankylosing spondylitis risk
- AML infiltration of bile duct identified as primary cause of acute pancreatitis in case report
- Medicinal and edible plants offer potential immunomodulatory mechanisms for various autoimmune diseases
- Intermittent and dynamic NPWT modes may offer advantages over continuous mode for wound healing outcomes
- Digital multi-domain intervention aims to prevent disability in older adults
- R-(+)-propranolol targets SOX18 for anti-hemangioma effect independent of beta-blockade
- Academic partnerships for family medicine education promote contextually grounded curricula and faculty development pathways
- Consistent monitoring principles exist for patients with familial Mediterranean fever across 42 publications
- FLASH radiotherapy transitions from experimental physics toward clinical precision and proton therapy workflows
- Exercise programs improve muscle mass and physical performance indicators in patients with liver cirrhosis
- Electroacupuncture ranks highest for total efficacy in acupuncture interventions for polycystic ovary syndrome
- Sarcopenia linked to 2.16-fold higher odds of atrial fibrillation in meta-analysis
- Symptom-informed updates increase predicted probabilities of hEDS and POTS in comorbid patients
- Higher AMH levels in PCOS patients correlate with higher oocyte yields and increased OHSS risk
- AI-assisted clinicians achieve 1.000 sensitivity in melanoma diagnosis but autonomous AI lacks clear clinical advantage
- Bibliometric analysis reveals expanding multidisciplinary research landscape for diabetes-related hearing loss
- ME/CFS linked to 7-fold higher odds of irritable bowel syndrome in meta-analysis
- AI models provide high accuracy for pulmonary inflammation and COVID-19 detection in diverse populations
- Predictive models for postoperative infection risk in hip fractures show AUC of 0.699 to 0.946
- Acupuncture effectively relieves pain and improves function in chronic low back pain, new guideline states
- Endoscopic closure of congenital bronchoesophageal fistula resolves cough in adult case
- Pyrotinib-based regimen achieves pathological complete response after non-response to standard neoadjuvant therapy in HER2+ breast cancer
- Upadacitinib shows rapid improvement in refractory acrodermatitis continua of Hallopeau
- FGF/FGFR signaling systems provide diverse mechanistic targets across multiple systemic autoimmune rheumatic diseases
- Essential oil interventions reduce acute nausea severity in patients with chemotherapy-induced breast cancer symptoms
- Network meta-analysis protocol aims to rank structured exercise interventions for fall prevention in dementia
- A staged framework integrates dry needling, Fascial Manipulation, and Yijinjing for chronic cervical myofascial pain
- Airway clearance techniques triple odds of treatment success in Chinese pneumonia patients
- Mongolian warm acupuncture improves clinical response in knee osteoarthritis vs oral meds
- Type 2 monoclonal antibodies reduce annual moderate-to-severe exacerbations in patients with eosinophilic COPD
- GNPTAB gene mutations characterize clinical phenotypes and skeletal deformities in Chinese mucolipidosis type II alpha/beta patients
- Tegileridine 0.5 mg reduces fentanyl-induced cough incidence from 28.7% to 11.1%
- Subcutaneous methotrexate improves ACR20 response and reduces GI side effects in RA
- Proposed methodology for developing a Core Outcome Set to standardize Traditional Chinese Medicine trials for pharyngitis
- Dual-channel supraglottic airways may shorten insertion time and reduce hypoxemia during upper gastrointestinal procedures
- IEN plus NACT shows greatest improvement in CD4+ counts among ranked strategies
- Elevated serum M2BPGi is associated with a 4.61 hazard ratio for hepatocellular carcinoma development
- Short-course antibiotic therapy yields comparable clinical and bacteriological success for adults with community-acquired pneumonia
- Opsin 3 serves as a potential therapeutic target for melanoma and inflammatory skin diseases
- Combination therapies with adalimumab, infliximab, tofacitinib, or upadacitinib increase serious infection risk in rheumatoid arthritis
- Integrated simulation-based training models provide a framework for perioperative point-of-care ultrasound competency
- Extracellular vesicles offer immunomodulatory mechanisms and targeted delivery for potential precision therapies in rheumatoid arthritis
- Comprehensive clinical reference system integrates etiology, diagnosis, and management for chronic pancreatitis complications
- EMG biofeedback assisted pelvic floor training improves muscle strength and reduces incontinence severity
- Gut microbiota dysbiosis linked to osteoarthritis pathology in preclinical and human studies
- Intestinal subepithelial myofibroblasts drive mucosal repair and pathological fibrosis in Inflammatory Bowel Disease
- FDA Approves Xeljanz XR (tofacitinib) for Multiple Inflammatory Conditions
- FDA Approves Xeljanz (tofacitinib) for Multiple Inflammatory Conditions
- FDA Approves Xeljanz (tofacitinib) for Pediatric Psoriatic Arthritis and Juvenile Idiopathic Arthritis
- Nafamostat mesylate reduces bleeding risk compared to citrate for anticoagulation during continuous renal replacement therapy
- Evaluating Treat to Target Outcomes in Elderly and Young Rheumatoid Arthritis Patients
- Belimumab linked to higher remission and low disease activity rates in SLE without glucocorticoids
- Upadacitinib 15 mg daily achieves DAS28-CRP ≤3.2 in 43.3% of patients versus 22.4% for adalimumab
- Deucravacitinib modulates up to 2529 genes and SLE-relevant gene sets including interferon-regulated genes
- Belimumab plus standard therapy shows numerically greater reductions in IgA, IgM, and anti-dsDNA antibodies
- Spontaneous splenic rupture occurs as a rare but life-threatening complication in enteric fever infections
- Higher Triglyceride-Glucose index is associated with increased risk of albuminuria in chronic kidney disease
- Tai Chi and Wuqinxi reduce pain while Pilates and Baduanjin improve physical function in knee osteoarthritis
- Peer support may impact fear of disease progression and psychological symptoms in patients with glioma
- Corticosteroid and cyclophosphamide exposure are associated with higher mortality in Middle Eastern and North African SLE
- Hand-dominant joint involvement patterns associate with better clinical outcomes in early rheumatoid arthritis
- Anti-DFS70 antibodies show high specificity but low sensitivity for excluding Systemic Lupus Erythematosus
- Aerobic and resistance exercise improve fatigue, physical function, and pain in systemic lupus erythematosus
- Intervention Mapping framework supports development of tailored behavioral interventions for stroke survivor rehabilitation
- Dipyridamole combined with immunoglobulin and aspirin improves clinical efficacy in children with Kawasaki disease
- Dupilumab as an off-label adjunctive approach facilitates corticosteroid minimization in severe pemphigus vulgaris
- Evaluating the Efficacy of Traditional Chinese Medicine Decoctions for Rheumatoid Arthritis Management
- Peripheral mechanisms like proton-sensing channels and neurovascular remodeling contribute to pain in osteoarthritis
- AI-driven in silico tools enhance sequence design and optimization for monoclonal antibody development
- Superficial heat therapy provides analgesic efficacy for dysmenorrhoea, endometriosis pain, and labor discomfort