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ENT (Otolaryngology)

76 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Hybrid minimally invasive oesophagectomy associated with lower rates of conduit necrosis, pneumonia, and nerve paralysis
ENT (Otolaryngology) Meta-analysis
Hybrid minimally invasive oesophagectomy associated with lower rates of conduit necrosis, pneumonia, and nerve paralysis Hybrid minimally invasive surgery shows fewer complications for esophageal cancer
This meta-analysis of 8 studies involving 6053 patients with oesophageal cancer found that hybrid minimally invasive oesophagectomy (HMIE) s…
A large review of surgical data suggests that a hybrid minimally invasive approach may reduce specific risks like pneumonia and nerve damage…
EGFR and TP53 mutations linked to worse survival in sinonasal squamous cell carcinoma
ENT (Otolaryngology) Meta-analysis
EGFR and TP53 mutations linked to worse survival in sinonasal squamous cell carcinoma Genetic markers linked to survival in sinonasal squamous cell carcinoma
A meta-analysis of 25 retrospective cohort studies including 1194 patients with sinonasal squamous cell carcinoma found that EGFR and TP53 m…
Specific genetic mutations and protein levels can help doctors predict how patients with certain head and neck cancers will respond to treat…
High tumor mutational burden correlates with improved objective response rate in HNSCC patients
ENT (Otolaryngology) Meta-analysis
High tumor mutational burden correlates with improved objective response rate in HNSCC patients High tumor mutation burden predicts better results in head cancer
This meta-analysis of 1472 patients with head and neck squamous cell carcinoma (HNSCC) found that high tumor mutational burden (TMB) is asso…
A high number of mutations in a tumor may help doctors predict which patients will respond best to immunotherapy.
Combination Therapies Improve Progression Free Survival in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
ENT (Otolaryngology) Meta-analysis
Combination Therapies Improve Progression Free Survival in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Combination therapies show promise for advanced head and neck cancer
This meta-analysis evaluated combination therapies involving targeted agents or immunotherapy with chemotherapy for patients with recurrent …
Combining immunotherapy or targeted drugs with chemotherapy may help patients with advanced head and neck cancer live longer without the dis…
Completion thyroidectomy follows total thyroidectomy for similar operative safety in differentiated thyroid cancer
ENT (Otolaryngology) Meta-analysis
Completion thyroidectomy follows total thyroidectomy for similar operative safety in differentiated thyroid cancer Less surgery may be safer for thyroid cancer patients
This meta-analysis of 43,362 patients evaluated the surgical safety of completion thyroidectomy (CT) compared to upfront total thyroidectomy…
For some thyroid cancers, a less extensive surgery may be safer with fewer complications.
Endoscopic parotidectomy reduces blood loss and drain output but clinical impact is limited
ENT (Otolaryngology) Meta-analysis
Endoscopic parotidectomy reduces blood loss and drain output but clinical impact is limited Endoscopic surgery shows lower blood loss for parotid gland tumors
This meta-analysis of 1188 patients compared endoscopic-assisted or fully endoscopic parotidectomy with conventional open surgery. Endoscopi…
Endoscopic techniques for parotid gland tumors may reduce blood loss and drainage during surgery while offering similar cosmetic results to …
Postoperative radiotherapy reduces local and peristomal recurrence rates in laryngeal cancer patients with preoperative tracheotomy
ENT (Otolaryngology) Meta-analysis
Postoperative radiotherapy reduces local and peristomal recurrence rates in laryngeal cancer patients with preoperative tracheotomy Radiotherapy May Lower Recurrence Risk After Laryngectomy for Cancer
This meta-analysis of 4339 patients evaluates the impact of postoperative radiotherapy (PORT) on recurrence rates following total laryngecto…
Postoperative radiotherapy may lower the risk of cancer returning in the throat area for patients who had a tracheotomy before surgery.
Camrelizumab and apatinib show higher response rates and survival in treatment-naive patients with ESCC
ENT (Otolaryngology) Meta-analysis
Camrelizumab and apatinib show higher response rates and survival in treatment-naive patients with ESCC Treatment Naive Patients Show Better Survival with Camrelizumab and Apatinib
This meta-analysis evaluates the efficacy of camrelizumab plus apatinib for advanced or metastatic esophageal squamous cell carcinoma. The a…
Patients with advanced esophageal cancer who have not had prior treatment may see better survival rates when using a combination of camreliz…
Zygomatic implants provide high survival rates for maxillary reconstruction in head and neck cancer patients
ENT (Otolaryngology) Meta-analysis
Zygomatic implants provide high survival rates for maxillary reconstruction in head and neck cancer patients Zygomatic implants show high survival for head and neck cancer
This systematic review and meta-analysis of 294 patients with extensive maxillary defects found a 97% overall implant survival rate. The ana…
New data shows zygomatic implants have a 97% survival rate, offering a reliable way to restore jaw function after cancer surgery.
Capecitabine significantly improves progression-free survival (HR 0.69) in advanced oesophagogastric adenocarcinoma
ENT (Otolaryngology) RCT
Capecitabine significantly improves progression-free survival (HR 0.69) in advanced oesophagogastric adenocarcinoma Trial shows capecitabine extends disease control for advanced stomach cancer
This Phase II randomized trial of 266 HER2-negative patients with advanced OGA found that maintenance capecitabine significantly improved pr…
A new trial shows that the drug capecitabine can help keep advanced stomach cancer from progressing for longer.
Music therapy cuts delirium risk by half in ICU patients, meta-analysis finds
ENT (Otolaryngology) Meta-analysis
Music therapy cuts delirium risk by half in ICU patients, meta-analysis finds Music Therapy May Reduce Delirium Risk for ICU Patients
This meta-analysis of 1,552 adult ICU patients found that music therapy significantly reduced delirium incidence (RR=0.49, 95% CI 0.40-0.60)…
Music therapy may help reduce delirium and improve sleep for adults in intensive care units, offering a safe way to support patient well-bei…
Remimazolam significantly reduces hypotension, bradycardia, and respiratory complications during gastrointestinal endoscopies
ENT (Otolaryngology) Meta-analysis
Remimazolam significantly reduces hypotension, bradycardia, and respiratory complications during gastrointestinal endoscopies Remimazolam shows fewer safety risks during gastrointestinal endoscopies
This meta-analysis of 2,455 patients found that remimazolam provides a superior safety profile compared to midazolam and propofol for gastro…
A new sedative may offer a safer way to keep patients stable and comfortable during procedures like gastrointestinal endoscopies.

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