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Do preterm children aged 0 to 2 years grow slower than full-term babies?

high confidence  ·  Last reviewed May 11, 2026

Preterm children (born before 37 weeks) often show slower growth in the first two years compared to full-term babies. A 2024 study found that preterm children had significantly lower growth rates for length and weight during the first 6 months, and for head circumference during the first 3 months, compared to full-term children 2. This slower growth is linked to lower levels of growth-related hormones like IGF-1 and IGFBP-3 in the first year 2. While many preterm children eventually catch up, early monitoring is important.

What the research says

A 2024 study directly compared growth rates of preterm and full-term children from birth to age 2 2. It found that preterm children had significantly lower growth rates for length and weight during the first 6 months of life, and for head circumference during the first 3 months 2. The study also measured serum levels of insulin-like growth factor 1 (IGF-1) and its binding protein (IGFBP-3), which are important for growth. These levels were significantly lower in preterm children during the first 12 months 2. The researchers noted that both biological factors (like hormone levels) and environmental factors (such as nutrition and care) influence growth rates in preterm children 2. Other research on preterm infants focuses on interventions to improve outcomes. For example, a trial of extended caffeine therapy in very preterm infants reduced intermittent hypoxia (low oxygen episodes) and lowered inflammation markers, which could support better growth 3. Another study found that starting full milk feeds from birth did not shorten hospital stays but reduced costs, suggesting it is a safe and economical feeding approach 4. These findings highlight that while preterm children initially grow slower, medical care and nutrition can help support their development.

What to ask your doctor

  • How should my preterm baby's growth be monitored in the first two years?
  • What are the normal growth milestones for a preterm baby, and when should I be concerned?
  • Could my baby benefit from extra nutritional support or supplements to improve growth?
  • Are there any specific tests (like IGF-1 levels) that might help assess my baby's growth?
  • What signs of slow growth or developmental delays should I watch for at home?

This question is drawn from common patient questions about Pediatrics and answered using cited medical research. We do not provide individualized advice.