What are the real-world results of using eptinezumab for ongoing episodic or chronic migraine attacks?
Eptinezumab is an intravenous treatment approved to prevent episodic and chronic migraine. Unlike standard preventives that work over months, real-world observations suggest it can help stop an active attack quickly. A 2026 Italian study found that pain scores dropped significantly within the first 10 to 20 minutes of the infusion 25.
What the research says
Another trial, the RESOLUTION study, looked at eptinezumab combined with patient education for people with chronic migraine and medication overuse. This 12-week study found that the drug reduced monthly migraine days and helped meet the thresholds for stopping the chronic migraine diagnosis 4.
What to ask your doctor
- How quickly might I feel relief from an ongoing migraine attack if I receive eptinezumab?
- Does eptinezumab help reduce my sensitivity to light and sound during an attack?
- Can eptinezumab help me meet the criteria to stop being classified as having chronic migraine?
- Is eptinezumab a good option for me if I also have medication overuse headache?
This question is drawn from common patient questions about Neurology and answered using cited medical research. We do not provide individualized advice.