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Scoping review protocol aims to assess IDEA toolkits for inclusive Canadian clinical trialsNew review aims to make clinical trials more inclusive in Canada

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Key Takeaway
Await results of this scoping review before applying its findings to clinical trial design.

This is a protocol for a scoping review, not a completed study. The planned review will assess existing toolkits designed to promote inclusivity, diversity, equity, and accessibility (IDEA) in clinical trials, with a contextual focus on Canada. The primary outcome is to evaluate the relevance and usability of these toolkits for supporting inclusive clinical trials in Canada. Secondary outcomes include identifying content gaps and gathering information to develop a tailored IDEA toolkit.

As this is a protocol only, no results, effect sizes, or population data are reported. The authors note that the study is a protocol for a planned review and results are not yet available. No safety data or funding information are provided.

The findings are intended to inform the development of a tailored IDEA toolkit to support equitable and representative clinical research across Canada. Clinicians and researchers should await the completed review before drawing any conclusions about the effectiveness of existing toolkits.

Clinical trials often don't reflect the diversity of the people they're meant to help. A new research protocol aims to change that by looking at existing toolkits designed to make trials more inclusive, diverse, equitable, and accessible.

The review, focused on Canada, will assess how useful and relevant these toolkits are for supporting inclusive clinical trials. It will also identify gaps in the current resources. The goal is to use this information to create a tailored toolkit that helps researchers run trials that include a wider range of people.

It's important to note that this is just a protocol, meaning the review hasn't been done yet. No results are available. The researchers have laid out their plan, but we don't know what they will find or if the toolkits actually work.

This work is still in the early stages. If successful, it could lead to better representation in clinical research, which means treatments that work for more people. But for now, it's a plan waiting to be executed.

What this means for you:
A planned review will assess tools for making clinical trials more inclusive in Canada.

Common questions

What is this review about?

This is a planned review that will look at existing toolkits designed to make clinical trials more inclusive, diverse, equitable, and accessible. The focus is on Canada. The goal is to see how useful these toolkits are and identify what's missing.

Are there any results yet?

No, not yet. This is just a protocol, which is a detailed plan for a review. The researchers have not collected or analyzed any data. Results will only be available after the review is completed.

Who will this help?

If successful, this review could help researchers in Canada run clinical trials that include a wider range of people. This means treatments could be tested on groups that are often left out, like older adults, ethnic minorities, or people in rural areas.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedJun 2026
View Original Abstract ↓
Many toolkits have been developed globally to help researchers design and conduct inclusive clinical trials, but their usability for Canada’s diverse population remains unclear. This scoping review aims to evaluate existing toolkits and assess their appropriateness in supporting inclusive clinical trials in Canada. We will conduct a comprehensive search of peer-reviewed and grey literature from April to August 2025 across multiple databases, including MEDLINE, EMBASE, CINAHL, PsycINFO, Cochrane, Scopus, and Web of Science. Search terms will combine inclusion, diversity, equity, and accessibility with terms for toolkits and clinical trials. Two independent reviewers will screen titles and abstracts using predefined inclusion and exclusion criteria, and full-text reviews will be conducted for eligible studies. Data will be extracted using a standardized form, focusing on toolkit content. We will summarize findings in a matrix and will present the extracted data in a tabular format, allowing easy comparison across toolkits. This scoping review aims to assess the relevance and usability of existing toolkits that support inclusive clinical trials, with a specific focus on their applicability to the clinical trials context. Given Canada’s diverse population, vast geography, and low participation rates among underrepresented groups, it is essential to determine whether current global resources meet local needs. The findings will help identify content gaps and inform the development of a tailored IDEA toolkit to support equitable and representative clinical research across Canada. The protocol was registered on the Open Science framework. The findings will be presented at relevant conferences, and the manuscript will be submitted to peer-reviewed journals.
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