Mode
Text Size
Log in / Sign up

Hands-free carotid ultrasound improves ROSC detection in cardiac arrestHands-free ultrasound speeds up heart restart checks for cardiac arrest patients

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Consider CADFlow as an adjunct for faster ROSC detection, but note the primary outcome did not reach statistical significance.

This randomized controlled trial enrolled 341 adult patients with in-hospital cardiac arrest across five affiliated teaching hospitals. Patients were assigned to either hands-free carotid ultrasound (CADFlow) or manual palpation of the carotid artery to guide resuscitation.

The primary outcome of ROSC success rate was non-significantly higher in the CADFlow group, with a 10-percentage-point absolute increase (43% vs. 33%, P=0.053). However, the mean time required to assess carotid pulsation was significantly shorter with CADFlow: 2.9 (SD 0.8) seconds versus 7.2 (SD 1.3) seconds (P<0.001). Secondary outcomes included chest compression parameters and carotid blood flow relationships, but detailed results were not reported.

Safety data, including adverse events, serious adverse events, and discontinuations, were not reported. Limitations of the study were not explicitly stated, and funding or conflicts of interest were not disclosed. The follow-up duration was also not reported.

Clinically, CADFlow may offer faster and more accurate ROSC detection and real-time feedback for CPR quality optimization. However, the lack of statistical significance for the primary outcome and unreported safety data warrant cautious interpretation. Further studies are needed to confirm these findings and assess clinical outcomes.

This randomized controlled trial involved 341 adult patients who experienced in-hospital cardiac arrest. The study took place across five affiliated teaching hospitals of medical universities. Participants were divided into two groups: one received hands-free carotid ultrasound using the CADFlow system, while the other group had clinicians use manual palpation to check for carotid artery pulsation.

The main results showed that the hands-free ultrasound group had a non-significantly higher rate of successful return of spontaneous circulation compared to the manual palpation group. The absolute numbers were 43 percent versus 33 percent, with a p-value of 0.053. However, the time required to assess carotid pulsation was significantly shorter in the ultrasound group. The mean time was 2.9 seconds versus 7.2 seconds for the manual group, with a p-value less than 0.001.

No adverse events or discontinuations were reported in the study. The hands-free system provided real-time feedback to help optimize CPR quality. While the improvement in success rates was not statistically significant, the faster assessment time is a clear benefit. This technology may help medical teams make quicker decisions during critical moments. Readers should note that this was a single trial with a specific sample size. More research may be needed to confirm these findings in broader settings.

What this means for you:
Hands-free ultrasound speeds up heart restart checks but did not significantly improve success rates in this trial.

Study Details

Study typeRct
EvidenceLevel 2
PublishedMay 2026
View Original Abstract ↓
OBJECTIVE: This study investigated the effectiveness and accuracy of hands-free carotid ultrasound (CADFlow, Continuous Auto Doppler Flow, Sensus Medical, Suzhou, China) for monitoring carotid blood flow in assessing the return of spontaneous circulation (ROSC), in comparison to manual palpation of major arterial pulses. METHODS: A total of 341 adult patients with in-hospital cardiac arrest were enrolled from five affiliated teaching hospitals of medical universities. Chest compression rate and depth were monitored using the Prehospital Advanced Life Support Manual Cardiopulmonary Resuscitation (PALMCPR, SunLife Science, Suzhou, China) system. In the CADFlow group, hands-free carotid ultrasound was used to monitor carotid pulsation, while the control group relied on manual palpation of the carotid artery to assess ROSC. The groups were compared in terms of ROSC success rates, time to ROSC determination, and ROSC misjudgment rates. Additionally, the relationships between chest compression parameters (depth and rate) and carotid blood flow were analyzed. RESULTS: The ROSC success rate was non-significantly higher in the CADFlow group than in the control group (43% vs. 33%, P = 0.053), corresponding to a 10-percentage-point absolute increase The mean time required to assess carotid pulsation was significantly shorter in the CADFlow group (2.9 (SD 0.8) s vs. 7.2 (SD 1.3) s, P < 0.001). Strong correlations were observed between chest compression depth and CADFlow parameters, suggesting that the system can effectively assess Cardiopulmonary Resuscitation (CPR) compression quality. CONCLUSIONS: The CADFlow hands-free carotid Doppler ultrasound system improves ROSC detection, shortens assessment time, and provides real-time feedback for CPR quality optimisation. TRIAL REGISTRATION: This clinical trial is registered with the Chinese Clinical Trial Registry (ChiCTR), with the registration number ChiCTR2200064633. The trial was registered on October 13, 2022. The full trial protocol is available upon request from the corresponding author.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.