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Meta-analysis profiles emergent surgical airways in head and neck conditions.

Meta-analysis profiles emergent surgical airways in head and neck conditions.
Photo by Richard Catabay / Unsplash
Key Takeaway
Note: Observational meta-analysis describes high complication risk for emergent surgical airways outside the OR.

This systematic review and meta-analysis pooled data from 14 observational studies, encompassing 1,011 emergent surgical airways (tracheostomy or cricothyrotomy) performed on patients with head and neck conditions. The population was predominantly male (79%, 95% CI 73.3-84.1%) with a mean age of 56.0 years (95% CI 51.5-60.5). The most common underlying cause was neoplasm (56.0%, 95% CI 37.4-73.7%), and the most frequent preceding symptom was dyspnoea (66.6%, 95% CI 44.3-85.7%).

The analysis reported a pooled mean complication rate of 16.8% (95% CI 8.8-26.6%) and an airway-related mortality rate of 0.2% (95% CI 0.0-0.8%). It found that the odds of successful decannulation were significantly increased for cases involving non-malignant tumours compared to malignant ones. Furthermore, the odds of complications were significantly increased when the procedure was performed in locations other than the operating room.

Safety and tolerability specifics were not reported. Key limitations include the observational nature of all included studies, which precludes causal inference, and the lack of reported primary outcome, follow-up duration, and comparator groups. The authors proposed a management pathway based on these associations, but clinical application requires caution due to the inherent biases in retrospective data and wide confidence intervals for several estimates.

Study Details

Study typeMeta analysis
EvidenceLevel 1
Follow-up672.0 mo
PublishedApr 2026
View Original Abstract ↓
Acute airway obstruction in patients with head and neck conditions often results in a 'can't intubate, can't oxygenate' (CICO) situation, which requires a different management approach than the airway emergency guidelines in the context of anaesthesiology. This systematic review and meta-analysis synthesized and analysed the patient demographics, causes, presentations, complications, operators, and outcomes of emergent surgical airways performed in patients with head and neck conditions, and proposed a targeted management pathway. A total of 1011 emergent surgical airways reported in 14 studies were identified, including 961 tracheostomies and 50 cricothyrotomies. The analysis of patient demographics showed that 79% of the patients were male (95% confidence interval (CI) 73.3-84.1%), and mean age was 56.0 years (95% CI 51.5-60.5 years). The most common underlying cause was neoplasm (56.0%, 95% CI 37.4-73.7%). The most common preceding symptom was dyspnoea (66.6%, 95% CI 44.3-85.7%). The pooled mean complication rate was 16.8% (95% CI 8.8-26.6%). The airway-related mortality rate was 0.2% (95% CI 0.0-0.8%). The odds of successful decannulation were significantly increased in non-malignant tumour cases compared to malignant cases. The odds of complications were significantly increased for emergent surgical airways performed in locations other than the operating room.
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