Case report details endoscopic resection for sphenoid sinus myofibroma in a 60-year-old woman

This publication is a case report with narrative review focusing on a 60-year-old female patient diagnosed with sphenoid sinus myofibroma. The intervention involved endoscopic endonasal transsphenoidal resection, with secondary outcomes including tumor excision, preservation of vital neurovascular structures, skull base reconstruction, neurological deficits, and complications. No comparator group was included in this single-patient analysis.

The reported results indicate that tumor excision was complete. The patient experienced no complications during the reported course. Neurological deficits improved significantly following the procedure. The authors note that skull base reconstruction was performed, though specific details on the reconstruction technique or materials are not provided in the text.

Limitations inherent to this study design include the small sample size of one patient and the fact that follow-up duration was not reported. Safety data regarding serious adverse events, discontinuations, and tolerability were not reported. The authors acknowledge that the rarity of the condition limits the ability to draw definitive conclusions about efficacy or safety for other patients.

Practice relevance is suggested cautiously, with the authors stating that endoscopic resection appears to be a safe and effective primary treatment for this rare condition. However, clinicians should interpret these results as preliminary observations rather than established evidence, given the absence of randomized data or larger observational cohorts.