Mode
Text Size
Log in / Sign up

Systematic review and meta-analysis of robotic versus laparoscopic surgery for rectal cancer

Systematic review and meta-analysis of robotic versus laparoscopic surgery for rectal cancer
Photo by Navy Medicine / Unsplash
Key Takeaway
Note low certainty and inconsistent effects for robotic vs laparoscopic rectal cancer surgery.

This systematic review and meta-analysis examined the comparative outcomes of robotic surgery versus laparoscopic surgery for rectal cancer. The analysis pooled data from 6121 patients across studies with a follow-up duration of 12.0 months. The primary outcome was not reported, while secondary outcomes included postoperative ileus, urinary retention, urinary function, and sexual function.

The meta-analysis indicated that urinary retention was lower in robotic surgery, though the specific effect size was not reported. In contrast, there was no significant difference observed for postoperative ileus, urinary function, or sexual function between the two surgical approaches. The authors noted that these effects were inconsistent and not sustained over time.

Significant limitations were identified, as all included studies were observational rather than randomized. Publication bias may have influenced the finding of lower urinary retention in robotic surgery. The authors conclude that effects were inconsistent, not sustained, and clinically modest, warranting cautious interpretation of the results.

Study Details

Study typeMeta analysis
Sample sizen = 6,121
EvidenceLevel 1
Follow-up12.0 mo
PublishedDec 2026
View Original Abstract ↓
BACKGROUND: Robotic and laparoscopic approaches are widely used for rectal cancer surgery. Although robotic systems provide enhanced visualization and dexterity, it remains unclear whether these advantages improve postoperative urinary and sexual function. METHODS: MEDLINE, Embase, Web of Science, and CENTRAL (2000-2025) were searched for studies comparing robotic and laparoscopic rectal cancer surgery. Outcomes included postoperative ileus, urinary retention, and urinary and sexual function. Random-effects meta-analysis was performed using RevMan. Study quality was assessed with MINORS, and certainty of evidence with GRADE. Publication bias was evaluated using funnel plots and Egger's test. RESULTS: Forty-four observational studies (6,121 patients) were included. Robotic surgery was associated with lower urinary retention, though this may reflect publication bias. No significant difference was found in postoperative ileus. Subgroup analyses at 3, 6, and 12 months showed no significant differences in urinary or sexual function. Although pooled results slightly favored robotic surgery, these effects were inconsistent, not sustained, and clinically modest. CONCLUSION: Robotic surgery may reduce urinary retention but shows no consistent functional superiority over laparoscopy. Outcomes at key follow-up points are comparable. As all studies were observational, evidence certainty is low, and findings should be interpreted cautiously.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.