Case report on laparoscopic excision of retroperitoneal mixed type unicentric Castleman disease

This publication is a case report describing the management of a 52-year-old female with retroperitoneal mixed type unicentric Castleman disease. The scope is limited to a single patient who underwent laparoscopic excision of the retroperitoneal mass. The authors report that postoperative recovery was uneventful and pathological examination confirmed the diagnosis of mixed type unicentric Castleman disease, with absolute numbers of 1 for the confirmed diagnosis.

The report does not include a comparator group, pooled effect sizes, or statistical analyses. No adverse events, serious adverse events, discontinuations, or tolerability issues were reported. The authors note that the patient remains under close follow-up surveillance.

A key limitation is the single-case design, which precludes generalization of findings. The authors acknowledge that retroperitoneal mixed type unicentric Castleman disease is clinically uncommon and possesses distinctive histopathological features, and they emphasize that awareness of this entity needs to be heightened. Practice relevance is restrained to noting the rarity of the condition and the role of surgical excision in this specific case.