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MCID for AOFAS Ankle Hindfoot Scale estimated at 4.1 to 7.8 points after ankle fracture surgeryStudy estimates meaningful improvement score for ankle fracture patients after surgery

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Key Takeaway
Consider AOFAS score changes of 4.1-7.8 points as potentially clinically relevant after ankle fracture surgery.

This multicenter randomized controlled trial aimed to determine the minimal clinically important difference (MCID) for the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle Hindfoot Scale. The study enrolled 148 patients with surgically treated unstable ankle fractures and followed them for 12 months. Median AOFAS scores improved significantly from 73.0 at 3 months to 85.0 at 12 months postoperatively (p < 0.001).

The primary outcome was the MCID for the AOFAS score, calculated using multiple methods. Anchor-based methods produced MCID estimates of 7.1 for the 3- to 6-month interval and 7.8 for the 6- to 12-month interval using the mean change method, and 0.5 and 5.5 for the same intervals using ROC curve analysis. Distribution-based methods yielded estimates of 9.2 at 3 months, 8.2 at 6 months, and 7.1 at 12 months. The minimal detectable change (MDC) was 3.5 at 3 months, 2.8 at 6 months, and 4.1 at 12 months.

Safety and tolerability data were not reported. Key limitations include the inherent uncertainty in MCID estimation, as different calculation methods produced varying results. The study did not evaluate a specific surgical or rehabilitation intervention. The practice relevance is that a change in AOFAS score between 4.1 and 7.8 points may be considered clinically relevant at the 1-year follow-up, but clinicians should recognize the methodological variability in these estimates.

Researchers wanted to understand what change in a standard ankle function score actually matters to patients recovering from surgery. They followed 148 people who had surgery for unstable ankle fractures at multiple centers for one year after their operation. The study used a common ankle assessment tool called the AOFAS Ankle Hindfoot Scale.

The main goal was to find the 'minimal clinically important difference' (MCID) – the smallest change in score that patients would notice as meaningful improvement. Using different calculation methods, they estimated this meaningful change falls between approximately 4 and 8 points on the 100-point scale over the first year. Patients' median scores improved from 73 at 3 months to 85 at 12 months after surgery.

It's important to know this study didn't test any specific treatment or rehabilitation method. The different calculation methods produced slightly different estimates, so the exact MCID number isn't certain. These results are specific to this particular ankle scale and to patients with surgically treated unstable fractures, and may not apply to other conditions or measurement tools.

For patients and doctors, this research provides a helpful reference point for understanding what score changes might reflect real patient-noticed improvement during recovery. It doesn't tell us which treatments work best, but helps interpret how patients are doing when using this specific measurement scale.

What this means for you:
A change of 4-8 points on a common ankle scale may signal meaningful improvement after fracture surgery.

Study Details

Study typeRct
Sample sizen = 148
EvidenceLevel 2
Follow-up12.0 mo
PublishedApr 2026
View Original Abstract ↓
BACKGROUD: The American Orthopaedic Foot and Ankle Society (AOFAS) Ankle Hindfoot Scale is frequently used as a patient-reported outcome measure (PROM) to evaluate recovery trajectories following foot and ankle injuries. This study aimed to determine the minimal clinically important difference (MCID) for the AOFAS score in patients with surgically treated unstable ankle fractures. METHODS: Data were obtained from the ROutine versus on DEmand removal Of the syndesmotic stabilisation screw (RODEO) trial, a multicenter randomized controlled trial evaluating the management of syndesmotic screw fixation following ankle fracture surgery. Eligible patients completed the AOFAS scale at 3, 6, and 12 months postoperatively. The MCID was calculated using both anchor-based approaches (mean change, receiver operating characteristic [ROC] analysis) and distribution-based approaches (minimal detectable change [MDC] and 0.5 standard deviation). RESULTS: A total of 148 patients were included, with a mean age of 47 years, and a male predominance of 63.5%. Median AOFAS scores improved significantly over time, rising from 73.0 at 3 months to 85.0 at 12 months postoperatively ( < 0.001). The MCID for the anchor-based mean change method was calculated to be 7.1 for the 3- to 6-month interval and 7.8 for the 6- to 12-month interval. ROC curve analysis indicated MCID values of 0.5 and 5.5 for these intervals, respectively. Distribution-based MCIDs were 9.2 at 3 months, 8.2 at 6 months, and 7.1 at 12 months. The MDC was 3.5 at 3 months, 2.8 at 6 months, and 4.1 at 12 months. CONCLUSIONS: Despite the extended recovery period, often up to 12 months, following surgical stabilization of unstable ankle fractures with syndesmotic injury, the AOFAS remains one of the most utilized PROMs in this context. Based on these findings, a change in score between 4.1 and 7.8 points should be considered clinically relevant at the 1-year follow-up.
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