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Surgical exploration resolved recurrent hemarthrosis in a patient with total knee arthroplasty.

Surgical exploration resolved recurrent hemarthrosis in a patient with total knee arthroplasty.
Photo by Nathan Rimoux / Unsplash
Key Takeaway
Note that surgical exploration may resolve recurrent hemarthrosis after TKA when angiography is negative or embolization is not feasible.

This case report details the management of a 69-year-old woman presenting with recurrent hemarthrosis after total knee arthroplasty. The patient underwent surgical exploration which included ligation, synovectomy, and spacer exchange. Angiography was negative, and embolization was not performed, leading to the decision for surgical intervention to identify occult bleeding sources or mechanical instability.

At two-year follow-up, the patient achieved complete symptom resolution and restored joint function. No adverse events, serious adverse events, discontinuations, or specific tolerability issues were reported in this single case. The study design is a case report with a literature review, involving a sample size of one patient.

Key limitations include the lack of a control group, the absence of statistical analysis, and the inherent constraints of a single-patient report. Statistical significance and confidence intervals were not reported. The certainty of the evidence is low due to the study phase and design.

In the setting of negative angiography or inability to perform embolization, surgical exploration may play a critical role in identifying occult bleeding sources, mechanical instability, and soft-tissue pathology in patients with recurrent hemarthrosis after total knee arthroplasty. However, this practice relevance is based on a single case and should be interpreted with caution.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
BackgroundRecurrent hemarthrosis following total knee arthroplasty (TKA) is an uncommon but challenging complication. While angiographic intervention is typically effective, some cases require surgical intervention.Case presentationWe report a 69-year-old woman who developed recurrent, non-traumatic hemarthrosis of the left knee 11 months after bilateral total knee arthroplasty. Diagnostic digital subtraction angiography (DSA) demonstrated an abnormal angiographic blush in the suspected branch of the lateral inferior genicular artery, raising suspicion of a possible pseudoaneurysm but without definitive diagnostic features. No active contrast extravasation was observed during angiography, and therefore transcatheter arterial embolization was not performed at that time. Surgical exploration revealed synovial hyperplasia, flexion instability, and pulsatile bleeding from a small artery at the posterolateral superior aspect of the knee joint. Ligation, synovectomy, and spacer exchange were performed.OutcomeThe patient experienced complete symptom resolution and restored joint function during a two-year follow-up.ConclusionThis case underscores that recurrent hemarthrosis after total knee arthroplasty may be multifactorial. In the setting of negative angiography or inability to perform embolization, surgical exploration plays a critical role in identifying occult bleeding sources, mechanical instability, and soft-tissue pathology.
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