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Structured training accelerates proficiency in pulsed Thulium laser enucleation for benign prostatic enlargement.

Structured training accelerates proficiency in pulsed Thulium laser enucleation for benign prostatic…
Photo by Navy Medicine / Unsplash
Key Takeaway
Consider that prior HoLEP experience may accelerate proficiency in ThuLEP within structured training programs.

This prospective analysis evaluated the learning curves associated with pulsed Thulium laser enucleation of the prostate (ThuLEP) among a cohort of three surgeons possessing varying levels of experience in HoLEP. The study population consisted of the first 100 consecutive ThuLEP procedures performed by these individuals. The primary objective was to assess how experience level influenced the acquisition of proficiency in this specific laser technique.

Regarding the main results, postoperative functional outcomes were comparable across all groups regardless of the surgeon's experience level. However, the learning curve analysis indicated that experienced surgeons demonstrated a steeper learning curve compared to others. Specifically, the highly experienced surgeon achieved proficiency approximately twice as quickly as the moderately experienced surgeon. Furthermore, performance plateaus in enucleation efficiency and enucleation time were reached roughly twice as quickly by the highly experienced surgeon. Additionally, the highly experienced surgeon required only about half the laser energy (kJ) compared to the moderately experienced counterpart.

Safety and tolerability data were not reported in this analysis. The study noted that the feasibility and safety of training for ThuLEP were feasible and safe when conducted within a structured training program. No adverse events, serious adverse events, discontinuations, or specific tolerability metrics were provided in the available data. Key limitations regarding the study design, setting, or funding were not reported in the input data.

The clinical relevance of these findings lies in the observation that prior experience in HoLEP may correlate with faster proficiency acquisition in ThuLEP when structured training is utilized. However, because the evidence is observational and specific safety metrics were not reported, these results should be interpreted with caution. Clinicians should recognize that while functional outcomes were consistent, the speed of proficiency acquisition varied significantly based on prior surgical experience.

Study Details

Study typeCohort
EvidenceLevel 3
PublishedApr 2026
View Original Abstract ↓
ObjectivesThis study aims to assess the learning curves associated with pulsed Thulium laser enucleation of the prostate (ThuLEP) among three surgeons with varying levels of experience in Holmium laser enucleation of the prostate (HoLEP) as a treatment for lower urinary tract symptoms (LUTS) secondary to benign prostatic enlargement, with pulsed ThuLEP being one of the newest systems for the surgical treatment of male LUTS.MethodsWe conducted a prospective analysis of the first 100 consecutive ThuLEP procedures performed by three surgeons with varying levels of HoLEP experience: one highly experienced (>1,000 prior HoLEP surgeries), one moderately experienced (>200 prior HoLEP surgeries), and one novice surgeon (with no prior HoLEP surgeries) undergoing a structured training program. The evaluation focused on perioperative characteristics, functional results, and safety outcomes.ResultsWhile postoperative functional outcomes were comparable across all groups, experienced surgeons demonstrated a steeper learning curve. The highly experienced surgeon achieved proficiency approximately twice as quickly as the moderately experienced one. Surgeons with prior HoLEP experience reached a performance plateau in enucleation efficiency (g/min) and enucleation time (min) roughly twice as quickly, while requiring only about half the laser energy (kJ). Training a HoLEP-inexperienced surgeon in ThuLEP proved both feasible and safe when conducted within a structured training program.ConclusionsPulsed ThuLEP shows a learning curve comparable to HoLEP for inexperienced surgeons when performed following a structured training program. Switching lasers is safe and feasible for surgeons already experienced in HoLEP.
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