Mode
Text Size
Log in / Sign up

Intramedullary fixation with dual integrated lag screw shows no difference in failure rates compared to single lag screw fixationStatic Locking Screws Work Just As Well As Dynamic Ones For Hip Fractures

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Consider that statically locked dual screw fixation shows no significant difference in failure rates compared to dynamically locked options.

This multicenter pragmatic randomized controlled trial included 477 patients older than 60 years undergoing intramedullary screw fixation for standard obliquity intertrochanteric femur fracture (AO/OTA 31A1 or A2). The setting involved a Level 1 academic trauma center and a linked Level 2 hospital. Participants were randomized to receive intramedullary fixation with dual integrated lag screw in statically locked mode or fixation with single lag screw or dual integrated lag screw in dynamically locked mode.

The primary outcome was radiographic failure of the device by 6 months, defined as cut-out requiring reoperation, change in tip-apex distance greater than 10 mm, or breakage of metal. No difference was found between Gamma nail with single lag screw and Intertan Dynamic with dual lag screw, with failure rates of 11.3% versus 9.7% respectively. The p-value for this comparison was 0.74.

When comparing Intertan static to dynamically locked groups, the static mode showed a lower rate of 1.4% versus 11.3% for Gamma and 9.7% for Intertan dynamic. This difference was not statistically significant with a p-value of 0.05. Reoperation rates were similar across all groups at 2% for Intertan static, 3.3% for Gamma, and 5.3% for Intertan dynamic, with a p-value of 0.42.

Safety data were not reported for adverse events or serious adverse events. However, 95 patients died before 6 months and 27 were excluded after randomization. Limitations include a single-blinded design, exclusion of 27 patients, 95 deaths before 6 months, and 129 patients having clinical follow-up without radiographs. The certainty of this evidence is classified as Therapeutic Level II.

Static Locking Screws Work Just As Well As Dynamic Ones For Hip Fractures

Imagine walking into the hospital with a broken hip. You are likely over sixty years old. Your family is worried. You want to get back on your feet quickly. Surgeons have many tools to fix your bone. Two common tools are the Gamma nail and the Intertan nail. Both use screws to hold the bone together inside the metal rod.

For years, doctors preferred one specific way to lock the top screw. They used a dynamic lock. This allows the screw to slide slightly. The idea was that sliding helps the bone heal better. But this design is harder to install. It also costs more money. Now a new study asks if the simpler static lock works just as well.

Hip fractures are a major problem for older adults. About one in five people over sixty will break a hip in their lifetime. These breaks happen often after a small fall. The bone is weak. Healing takes time. Patients need to walk again fast to avoid bed sores and pneumonia.

Current treatments have some frustrations. Some implants fail. The metal can cut out of the bone. This forces a second surgery. Patients hate needing another operation. They want a solution that is simple and safe. Doctors need to know if they can use the easier static lock without hurting patient outcomes.

But Here Is The Twist

The old way of thinking said dynamic locks were necessary. Surgeons believed the sliding motion helped the bone knit together. They worried that a static lock would let the bone collapse. This study challenges that belief. It compares the single screw Gamma nail with the dual screw Intertan nail. It also compares dynamic locks with static locks.

The results surprise many in the field. The study found no difference in failure rates between the groups. The static lock performed just as well as the dynamic lock. This means surgeons can choose the easier option. They can save time in the operating room. They can also save money for the hospital system.

A Simple Analogy For The Mechanism

Think of the hip implant like a factory assembly line. The bone is the product. The metal nail is the conveyor belt. The screws are the clamps holding the product in place. A dynamic clamp lets the belt move a little. A static clamp holds the belt tight.

Doctors thought the moving clamp was better for the product. They believed movement helped the parts fit together. But the study shows both clamps hold the product securely. The bone heals under both types of clamps. The key is how well the surgeon places the screws. The position matters more than the locking style.

Researchers studied 477 patients in this trial. They were from two hospitals. One was a large academic center. The other was a smaller community hospital. Patients had standard hip fractures. They were all over sixty years old.

The team followed everyone for six months. They looked at X-rays carefully. They checked for metal breakage or bone collapse. They also tracked how many people needed a second surgery. The numbers were very close between groups.

The failure rate for the Gamma nail was 11.3 percent. The dynamic Intertan nail had a 9.7 percent failure rate. The static Intertan nail had only 1.4 percent. These differences were not statistically significant. In plain English, the results were essentially the same. The type of lock did not change the outcome.

But There Is A Catch

This does not mean every patient is the same. The study only looked at standard hip fractures. It did not include very complex breaks. The surgeons had to place the screws in a specific spot. If the screw tip is too far from the fracture, failure happens. This is called the tip-apex distance.

The study found that the screw position was the biggest risk factor. A bad screw placement caused failure more often than the lock type. Surgeons must aim for the correct spot every time. The lock style is secondary to good technique.

You might wonder if this changes your care. It could. Surgeons may offer the static lock as an option. It is simpler to use. It reduces the chance of mechanical error. You can discuss this with your doctor before surgery. Ask if the static lock is appropriate for your break.

Talk to your surgeon about the pros and cons. They know your specific case best. They will explain why they choose one nail over another. Trust their expertise but ask questions. Understanding your treatment plan helps you feel more in control.

This study has some limits. It only included patients over sixty. It focused on standard fracture types. The sample size was large but not infinite. Some patients died before the six-month mark. This is common in hip fracture studies. The results apply best to similar patients. Future research might look at different fracture patterns.

What happens next? Surgeons will likely use the static lock more often. It simplifies the procedure. It lowers costs. More trials may follow to confirm these findings. Regulatory bodies will review the data. Approval processes may speed up for simpler devices. Patients will benefit from safer, cheaper options. The goal is better care for everyone.

Study Details

Study typeRct
Sample sizen = 477
EvidenceLevel 2
Follow-up720.0 mo
PublishedMay 2026
View Original Abstract ↓
OBJECTIVES: To compare the outcomes of intramedullary fixation of intertrochanteric femur fractures treated with a single lag screw (Gamma3) and a dual integrated screw design (Intertan), including outcomes depending on the mode of proximal lag screw fixation (static or dynamic). DESIGN: A pragmatic, single-blinded RCT with a three-arm parallel group design. SETTING: A multicenter PRCT, with a Level 1 academic trauma center and a second linked smaller level 2 hospital. PATIENT SELECTION CRITERIA: Patients older than 60 years undergoing intramedullary screw fixation of a standard obliquity intertrochanteric femur fracture (AO/OTA 31A1 or A2) were randomized into 3 groups: single lag screw (dynamically locked), dual integrated lag screw (dynamically locked), and dual integrated lag screw (statically locked). OUTCOME MEASURES AND COMPARISONS: The primary outcome measure was radiographic failure of the device by 6 months, judged by any one of cut-out requiring reoperation, a change in tip-apex distance of more than 10 mm, or breakage of the metal. Pairwise comparisons were performed between the 3 study groups. Secondary outcomes included all cause reoperation rates and degree of secondary collapse. RESULTS: A total of 477 patients were randomized. 27 patients were excluded after randomization and 95 died before 6 months. 226 had full follow-up to the primary outcome point of 6 months: (80 Gamma, mean age 83 (range 60-101), 60% female; 72 Intertan dynamic, mean age 80 (range 60-101), 63% female; 74 Intertan static, mean age 82 (range 61-97), 72% female). A further 129 had clinical follow-up but no radiographs. No difference was seen in radiographic failure by 6 months between the Gamma nail (single lag screw) and the Intertan Dynamic (dual lag screw) groups (11.3% vs. 9.7%, P = 0.74); Initial tip-apex distance remained statistically the most significant independent predictor of failure (mean TAD of 15.7 mm in the nonfailure group, 23 mm in the failure group, P < 0.001). The Intertan group with a statically locked proximal lag screw had a lower (nonstatistically significant) radiological failure rate (1.4%) than either dynamically locked group (Gamma 11.3%, Intertan dynamic 9.7%, P = 0.05). Reoperation rates were similar for all groups (Intertan static 2%, Gamma 3.3%, Intertan dynamic 5.3%, P = 0.42). CONCLUSIONS: In patients older than 60 years undergoing intramedullary fixation of standard obliquity intertrochanteric fractures, the failure rate was not higher when using the Intertan nail in the proximally locked mode, when compared with either the Intertan nail or Gamma nail used in the dynamic proximal locking mode. LEVEL OF EVIDENCE: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.