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Reverse shoulder arthroplasty with 155° distalization yields better tuberosity healing than 135° lateralization in proximal humerus fracturesDoes a different shoulder implant angle affect bone healing after a bad break?

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Key Takeaway
Consider 155° distalization for better tuberosity healing, but note functional outcomes were similar regardless of healing status.

This randomized controlled trial enrolled 79 patients aged 65 years or older with Neer 3- or 4-part proximal humerus fractures or displaced Neer 2-part fractures with osteoporosis and/or rotator cuff tears. Patients received reverse total shoulder arthroplasty with either a 155° stem with 2.5 mm of distalization or a 135° stem with 4 mm of lateralization, both using the Univers Revers Total Shoulder System. Follow-up occurred at 6, 12, and 24 months postoperatively.

The primary outcome of greater tuberosity nonhealing occurred in 3 patients (7.9%) in the 155° distalized group versus 12 patients (31.6%) in the 135° lateralized group, representing a relative risk of 4.0 (95% CI: 1.23-13.05, P = .022). Secondary outcomes including range of motion, visual analog scale pain scores, Constant-Murley scores, and Quick-DASH scores showed no significant differences between groups (P > .050).

Notably, among cases with nonhealed greater tuberosities, external rotation was significantly lower in the 155° distalized configuration (-17° ± 6) compared to the 135° lateralized configuration (15° ± 19, P = .006). Within the 155° distalized group, nonhealed tuberosities were associated with substantially reduced external rotation (-17° ± 6) compared to healed cases (20° ± 18, P = .006).

Safety and tolerability data were not reported. The study was powered a priori and included 2-year follow-up with healing assessments by two independent shoulder surgeons. However, the clinical setting was not reported, and funding sources and conflicts of interest were not disclosed. While the randomized design supports causal inference for the primary healing outcome, the similar functional results between groups despite different healing rates suggest healing may have limited influence on overall functional outcomes in this population.

When an older adult suffers a severe shoulder fracture, surgeons often use a special joint replacement called a reverse total shoulder arthroplasty. A key part of the surgery is reattaching a piece of bone called the greater tuberosity, which is crucial for shoulder movement. A new study asked whether the angle of the implant's stem affects how well that bone heals.

The trial compared two implant angles in 76 patients who were followed for two years. It found that using a 155-degree stem led to better bone healing than a 135-degree stem. Specifically, 12 patients in the 135-degree group had non-healing compared to only 3 in the 155-degree group. However, this difference in healing didn't translate to better overall function—patients in both groups reported similar levels of pain, range of motion, and ability to use their arm.

There was one notable twist: in the few cases where the bone didn't heal in the 155-degree group, those patients had significantly worse ability to rotate their arm outward. The study was relatively small, and we don't have details on safety events or potential side effects. The results suggest that while one implant angle might promote better bone healing on an X-ray, what matters most to patients—their pain and function—wasn't clearly different between the two approaches.

What this means for you:
Implant angle affected bone healing, but not patients' pain or function after a severe shoulder fracture.

Study Details

Study typeRct
Sample sizen = 78
EvidenceLevel 2
Follow-up780.0 mo
PublishedApr 2026
View Original Abstract ↓
BACKGROUND: Controversy remains regarding whether humeral neck shaft angle influences tuberosity healing in reverse total shoulder arthroplasty for proximal humerus fracture (PHF). This study aimed to compare the tuberosity healing rates between reverse total shoulder arthroplasty using a lateralized and a distalized configuration of the Univers Revers Total Shoulder System for PHFs. The secondary objective was to evaluate functional outcomes based on stem inclination and tuberosity healing status. METHODS: This randomized controlled trial enrolled patients ≥65 years with a Neer 3- or 4-part PHF or a displaced Neer 2-part PHF with osteoporosis and/or a rotator cuff tear. Patients were randomized into 2 groups: 135° stem with 4 mm of lateralization or 155° stem with 2.5 mm of distalization. An a priori power analysis determined a sample size of 78 patients to detect a 15% difference in tuberosity healing between groups with statistical significance. Healing of the tuberosities was assessed by 2 independent shoulder surgeons on radiographs at 6, 12, and 24 months postoperatively. Range of motion (ROM) and patient-reported outcomes (PROs) were compared. PROs included the visual analog scale for pain, Constant-Murley score, and Quick-Disabilities of the Arm, Shoulder and Hand. Post hoc analyses compared outcomes by greater tuberosity healing and implant configuration. RESULTS: A total of 79 patients were enrolled, and 38 in each group completed at least a 2-year follow-up. Nonhealing of the greater tuberosity occurred in 3 patients in the 155°-distalized group and 12 in the 135°-lateralized group (P = .009). The relative risk of greater tuberosity nonhealing in the 135°-lateralized group compared to the 155°-distalized group was 4.0 (95% CI: 1.23-13.05, P = .022) at 24 months. ROM and PROs were similar between groups (P > .050). In nonhealed greater tuberosity cases, the 155°-distalized configuration showed significantly lower external rotation than the 135°-lateralized configuration (-17° ± 6 vs. 15° ± 19, P = .006). No significant differences in ROM and PROs were found between implant types in healed cases (P > .050). Within the 155°-distalized group, nonhealed greater tuberosity was linked to reduced external rotation compared to healed greater tuberosity (-17° ± 6 vs. 20° ± 18, P = .006), while ROM and PROs were comparable in the 135° group regardless of healing status (P > .050). CONCLUSION: Tuberosity healing with the Univers Revers Total Shoulder System was more frequent with the 155°-distalized configuration, although functional outcomes were comparable to those achieved with the 135°-lateralized design. While successful tuberosity healing was critical to optimize shoulder rotation in the 155°-distalized group, healing had minimal influence on functional outcomes in the 135°-lateralized group.
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