Researchers analyzed data regarding muscle thickness in people living with cystic fibrosis. They used ultrasound technology to measure the quadriceps, which are the large muscles in the front of the thigh. The study found that these patients had a significant reduction in muscle thickness and cross-sectional area compared to healthy individuals.
The results also showed a moderate link between these ultrasound measurements and other health markers. These included lung function, fat-free mass index, and overall muscle strength. This suggests that measuring muscle size with ultrasound may help doctors track how well a patient is doing physically.
It is important to note that this evidence comes from a meta-analysis with some limitations. The data was varied across different studies, and many of the original studies had small sample sizes. While the findings show a clear link between muscle loss and cystic fibrosis, more research is needed to confirm how often ultrasound should be used in daily clinical care.