Prospective cohort study links NETosis markers to postoperative frailty in advanced ovarian cancer patients.
Do blood markers predict weakness after ovarian cancer surgery?
This prospective cohort study evaluated 189 advanced ovarian cancer patients to assess neutrophil extracellular trap markers. Significant di…
Three specific blood markers linked to inflammation can predict weakness in women recovering from advanced ovarian cancer surgery.
Retrospective cohort of 162 HLH patients shows combined therapy improves survival over monotherapy
Study links certain factors to survival in patients with hemophagocytic lymphohistiocytosis
This retrospective cohort study analyzed 162 patients with hemophagocytic lymphohistiocytosis (HLH) diagnosed across four medical centers. T…
Survival rates for hemophagocytic lymphohistiocytosis patients improved when combined therapy regimens were used instead of single treatment…
Retrospective cohort links IINS and RLR to survival in esophageal cancer surgery patients.
New blood markers may help predict survival after esophageal cancer surgery
This retrospective cohort study evaluated 660 esophageal cancer patients who underwent radical surgery. The inflammation–immunity–nutrition …
New blood markers that measure inflammation and immunity outperform standard staging to predict survival after esophageal cancer surgery.
Gene expression programs associated with survival and recurrence in early-stage lung adenocarcinoma patients
Why Your Lung Cancer Risk Is Not The Same As Your Neighbor's
This retrospective cohort study evaluated gene expression programs in early-stage (IA/IB) lung adenocarcinoma patients. The analysis utilize…
Hidden immune signals in early lung cancer act like a weather forecast, predicting who will stay well and who faces a quick return of the di…
VEXAS Syndrome Clinical Features and Treatment Outcomes in a Chinese Cohort of 16 Patients
Small study links UBA1 gene variants to blood and inflammatory issues in China
This retrospective cohort study of 16 Chinese patients describes main clinical features and treatment responses in VEXAS syndrome. Constitut…
A specific genetic change called a UBA1 variant was found in 81 percent of patients in China with blood disorders and inflammation affecting…
Severe heat stroke correlates with longer hospital stays and higher oxidative stress markers compared to mild cases.
Why Your Body Fights Heat Stroke
This prospective cohort study included 49 patients with heat stroke (34 mild and 15 severe cases) and healthy volunteers. Severe cases demon…
Severe heat stroke disables a key body defense switch, letting rust damage organs and causing patients to stay in the hospital much longer.
Combined neutrophil-to-lymphocyte ratio predicts progression-free survival in metastatic cervical cancer patients treated with immune checkpoint inhibitors.
A Simple Blood Test May Predict Cervical Cancer Treatment Success
This retrospective cohort analysis evaluated 148 individuals with metastatic or recurrent cervical cancer treated with immune checkpoint inh…
A simple blood test ratio may predict who responds best to immunotherapy for advanced cervical cancer, helping doctors tailor treatment with…
Serplulimab with FOLFOX showed disease control in AFP-producing gastric adenocarcinoma with liver metastases.
Rare Stomach Cancer Shrinks After New Combo Treatment
This case report and literature review describes a 67-year-old man with AFP-producing gastric adenocarcinoma and liver metastases treated wi…
A rare stomach cancer that spread to the liver shrank dramatically when doctors combined standard chemotherapy with a newer immune-boosting …
STAT1 and IL-7 show diagnostic potential for ovarian carcinoma subtypes in cohort study
Two Tiny Signals Could Help Doctors Tell Apart Two Ovarian Cancers
A cohort study analyzed transcriptome data from 68 patients with high-grade and low-grade serous ovarian carcinoma. STAT1 and IL-7 demonstra…
Two tiny gene signals may help doctors distinguish between two ovarian cancer types when biopsy results are unclear, guiding the right treat…
EBV DNA positivity links to MS risk genes in a cross-ancestry study of 617,186 participants.
A Common Virus May Hold the Key to MS — Here's Why
This cross-ancestry genome-wide association study analyzed 617,186 individuals to investigate the relationship between Epstein-Barr virus (E…
A virus almost everyone carries may quietly flip immune switches that set off multiple sclerosis by altering how B cells signal to T cells.
Observational study identifies distinct immunophenotypic signatures in ME/CFS and long COVID compared to healthy controls.
Two Look-Alike Illnesses May Finally Have Separate Fingerprints
This observational study analyzed peripheral blood mononuclear cells from 207 participants with myalgic encephalomyelitis/chronic fatigue sy…
For the first time, scientists can tell two confusing, often-mixed-up illnesses apart by looking at specific immune cells in the blood.
Review discusses ACSL4 metabolic switch potential in hepatocellular carcinoma therapy strategies
Review suggests metabolic switch concept may guide future liver cancer treatments
This mini-review examines the role of ACSL4 as a metabolic switch rather than a static oncogenic factor in hepatocellular carcinoma. The aut…
Viewing a liver cancer protein as a metabolic switch could guide new therapies that boost a specific cell death process to fight tumors.