Review of CAR-T cell therapy for pancreatic ductal adenocarcinoma reports no specific outcomes or safety data.
First CAR-T for Pancreatic Cancer Approved
This narrative review addresses the application of CAR-T cell therapy for pancreatic ductal adenocarcinoma. However, the source explicitly s…
For the first time, a new drug approved for pancreatic cancer uses immune cells to attack solid tumors instead of just blood cancers.
Meta-analysis links long-term glucocorticoid use and SLE duration to high osteoporosis prevalence in patients.
Lupus Patients Face Hidden Bone Loss Risk
This systematic review and meta-analysis evaluated 59 studies involving patients with systemic lupus erythematosus (SLE) to assess bone heal…
Bone loss affects 1 in 6 lupus patients, a hidden risk often overlooked due to the disease and its treatments.
Narrative review examines immune modulation strategies for beta-cell replacement in type 1 diabetes
Can changing the immune system help replace damaged cells in Type 1 diabetes?
This narrative review explores immune modulation strategies for beta-cell replacement, including graft-intrinsic immune engineering, local g…
New strategies aim to stop the immune system from attacking insulin cells, offering a potential path to replace damaged tissue in Type 1 dia…
Narrative review explores immune monitoring for relapse prediction after AML stem cell transplant
Can better immune monitoring help predict relapse in leukemia patients after stem cell transplants?
This narrative review examines immune monitoring methodologies for predicting relapse in acute myeloid leukemia patients after allogeneic he…
New immune monitoring tools could spot leukemia relapse risks earlier than standard tests after stem cell transplants, helping doctors tailo…
Systematic review synthesizes immune and genetic factors in African SARS-CoV-2 populations
Why Africa saw milder COVID-19
This narrative synthesis reviews 40 studies from African settings regarding SARS-CoV-2 infection. The authors describe widespread pre-existi…
Africa saw milder COVID-19 because unique genes and immune defenses helped people fight the virus without getting severely sick.
Review of ISG15 pathway targeting for inflammatory and cardiovascular diseases
A Tiny Protein That Fuels Your Inflammation
This narrative review examines the potential of targeting the ISG15 pathway to treat inflammatory diseases, including skin, cardiovascular, …
Understanding this protein could lead to better medicines for skin, heart, and brain diseases.
Budesonide-glycopyrronium-formoterol fumarate dihydrate improved lung function and reduced severe exacerbations versus budesonide-formoterol in inadequately controlled asthma.
New Asthma Drug Cuts Attacks Without Recent Crisis
This phase 3 randomised, double-blind, double-dummy, parallel-group trial evaluated budesonide-glycopyrronium-formoterol fumarate dihydrate …
A new asthma combo therapy improves breathing and lowers severe flare-up risk for patients who haven't had a recent emergency room visit.
Home-based e-based exercise protocol feasibility study for patients with multiple sclerosis and comorbidities
Working Out From Home Could Slow Multiple Sclerosis Progression
This protocol describes a home-based e-based physical exercise program for patients with multiple sclerosis (pwMS) with and without comorbid…
A new trial tests if twice-weekly online resistance exercise from home can improve walking ability and reduce disease activity in people wit…
Natural and synthetic compounds suppress inflammasome activation in NLRP3-driven pathologies
Your body has a built-in alarm system. It wakes up when you get a sore throat or a fever. But sometimes, this alarm gets stuck in the "on" position. That stuck alarm causes chronic pain and swelling. Scientists are finally learning how to turn it off.
This systematic review examined molecular mechanisms involving natural compounds like oridonin and pristimerin, alongside synthetic inhibito…
A hidden protein key inside your cells triggers the stuck alarm that causes chronic pain and swelling, and scientists now know how to stop i…
Peri- and postmenopausal hormonal changes may exacerbate asthma, rhinitis, cough, allergies, hypersensitivity, anaphylaxis, and angioedema.
Menopause Changes Allergy Rules for Women
This systematic review examines the association between declining and fluctuating estrogen and progesterone levels and various allergic and …
Menopause can worsen allergies like hay fever and asthma because dropping estrogen levels make your immune system more reactive to triggers.
AQST-109 sublingual film shows faster time-to-peak concentration than epinephrine autoinjectors in healthy adults.
The Allergy Shot That Goes Under Your Tongue Instead
A phase 3 RCT in healthy adults compared AQST-109 sublingual film to intramuscular epinephrine. AQST-109 had a faster time-to-maximum plasma…
A dissolving film under the tongue delivers epinephrine faster than an EpiPen, offering a needle-free option for severe allergy emergencies.
Occupational toxic particle exposure linked to increased pulmonary sarcoidosis risk in meta-analysis
The Dusts and Fumes Linked to a Strange Lung Disease
This systematic review and meta-analysis evaluated 13 studies published between 2000 and 2025 to assess occupational exposures as risk facto…
A review of 13 studies found that specific workplace dusts and chemicals are linked to sarcoidosis, a mysterious lung disease that leaves ti…