Narrative review discusses renal risks in inflammatory bowel disease patients
Kidney risks for people with inflammatory bowel disease remain unclear and need more study
This narrative review examines renal complications in individuals with inflammatory bowel disease. The authors highlight that causal pathway…
People with inflammatory bowel disease face kidney risks, but current evidence relies on animal studies and lacks human proof.
Consolidation immunotherapy shows no survival benefit over induction alone in stage III non-small cell lung cancer
Adding immunotherapy after chemo may not help stage III lung cancer
This retrospective cohort study evaluated 196 patients with stage III non-small cell lung cancer across 4 hospitals. Patients received induc…
Stage III lung cancer patients saw no clear survival gain when immunotherapy was added after chemo and radiation.
Single-center study finds 42.70% allergen sensitization rate in children in Kashi Prefecture
Kids in Kashi face rising allergy risks year-round
This single-center cross-sectional retrospective study evaluated 2,124 children in Kashi Prefecture, China. Overall sensitization to common …
More than 4 in 10 kids in western China show signs of allergy sensitivities, even without symptoms, pointing to hidden risks from dust, pets…
Web-based tool improves phenotype capture for Common Variable Immunodeficiency in UK cohort
New Tool Maps Rare Immune Disease Patterns To Guide Treatment
This cohort study of 526 adults with Common Variable Immunodeficiency implemented a web-based Phenotype Capture Tool with clinician training…
A new tool now maps rare immune disease traits with high accuracy, helping doctors match patients to better treatments.
Meta-analysis shows pharmaceutical care improves asthma and COPD management outcomes in 4173 patients
Pharmacist care improves asthma and COPD control and reduces hospital visits
This meta-analysis evaluated pharmaceutical care interventions versus original treatment only in 4173 asthma or COPD patients. The analysis …
A review of 4173 patients found that pharmacist care significantly improved inhaler use, medication adherence, and asthma control while lowe…
Systematic review on allergic rhinitis links environmental exposures and microbiome changes
Researchers find environment and microbes shape allergy risk
This systematic review synthesizes evidence on environmental exposures and the microbiome in allergic rhinitis. It finds that air pollutants…
Air pollution, early antibiotics, and farm life may change your nasal microbes, raising or lowering allergy risk, a new review suggests.
Systematic review identifies 16 mRNA vaccine antigens for pancreatic cancer immunotherapy
New mRNA vaccine targets show promise for pancreatic cancer treatment
This systematic review evaluates 16 mRNA vaccine candidate antigens for pancreatic cancer. ADAM9 and PAK2 showed high expression and associa…
A review of mRNA vaccine candidates found specific targets that could help fight pancreatic cancer, though challenges remain before patients…
Mini-review explores oxidized mannan-conjugated MOG peptide for multiple sclerosis immunotherapy
New MS Treatment Could Teach Immune System To Stop Attack
This mini-review summarizes preclinical evidence on oxidized mannan-conjugated MOG peptide (OM-MOG35-55) for multiple sclerosis. It highligh…
A new treatment for multiple sclerosis may teach the immune system to stop attacking nerves without shutting down protection or causing majo…
Narrative review discusses eosinophil abundance associations with lung cancer prognosis and immunotherapy response
High eosinophil counts in lung cancer tumors may signal better responses to immune therapy.
This narrative review examines eosinophil abundance in tumor tissues and peripheral blood among lung cancer patients. Authors report associa…
Elevated eosinophil counts in lung cancer patients often link to improved responses to immune checkpoint inhibitors, though their exact role…
Systematic review and meta-analysis of ENA seropositivity in ANA-IIF-negative connective tissue disease populations
A Negative ANA Test Can Still Miss Autoimmune Disease, Study Finds
This systematic review and meta-analysis evaluated the frequency of extractable nuclear antigen (ENA) seropositivity among 28,552 ANA-IIF-ne…
A negative ANA test doesn't always rule out autoimmune disease, with 14% of negative cases still showing other key antibodies.
Narrative review outlines miRNA-based strategies and challenges in pancreatic ductal adenocarcinoma management.
Tiny RNA tricks could help immunotherapy fight pancreatic cancer
This narrative review examines miRNA-based strategies within the context of pancreatic ductal adenocarcinoma treatment options available tod…
MicroRNAs may help immunotherapy work in hard-to-treat pancreatic cancer by reshaping the tumor environment.
Narrative review explores pattern recognition receptor signaling roles in pediatric otitis media management.
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This narrative review examines pattern recognition receptor signaling, including TLRs, NLRs, RLRs, and CLRs, within pediatric otitis media. …
Smarter immune targeting could stop recurring ear infections in children without relying on heavy antibiotic use or surgery.