High NEK6 expression linked to poor colorectal cancer prognosis and glycolytic subtype dominance
New Target Found to Stop Colon Cancer From Feeding Itself
This cohort study identified three malignant colorectal cancer subtypes, with the Glycolysis-C1 subtype exhibiting a high-glycolytic state. …
A newly mapped cancer sugar pathway reveals NEK6 as a target that could starve colon tumors and improve treatment.
Multimodal fusion model predicts pathological complete response in 262 breast cancer patients receiving neoadjuvant therapy.
New MRI and Blood Test Combo Predicts Breast Cancer Treatment Success Early
This cohort study evaluated a multimodal fusion model integrating deep learning features from longitudinal DCE-MRI, peripheral blood inflamm…
A smart mix of early MRI scans and blood markers now predicts if breast cancer treatment will work, helping doctors personalize care sooner.
Retrospective Cohort Finds Elevated NLR and PLR Associated with Complications and Survival in Hepatocellular Carcinoma
Post-surgery blood test predicts liver cancer survival better than surgery type alone
This retrospective multicenter cohort study evaluated 74 hepatocellular carcinoma patients undergoing curative hepatectomy or orthotopic liv…
A simple blood test taken months after liver surgery can predict survival better than knowing just how the operation was done.
Elevated hs-CRP associates with airflow limitation and PRISm in 335 adult liver transplant recipients.
High blood inflammation markers raise risk of poor lung health in liver transplant patients
This cohort study of 335 adult liver transplant recipients found that elevated inflammatory markers, specifically hs-CRP >3 mg/L, were assoc…
High blood inflammation markers may signal worse lung function in liver transplant patients, a link doctors have never studied before.
PD-L1-armored CAR-T followed by allo-HSCT yields 7-year remission in refractory B-cell ALL
New Leukemia Treatment Keeps Adult Patient Cancer Free For Seven Years
This retrospective observational analysis of a single clinical case describes an adult patient with early-relapsed, chemorefractory B-cell a…
A new dual-targeted therapy helped an adult with tough leukemia stay cancer-free for seven years after standard treatments failed.
Narrative review covers adoptive cell therapy modalities for ovarian cancer.
Cell therapy could stop ovarian cancer from coming back
This narrative review examines adoptive cell therapy (ACT) modalities, including tumor-infiltrating lymphocytes (TILs), chimeric antigen rec…
New immune cell treatments show promise for fighting ovarian cancer when standard drugs stop working.
Narrative review on ICIs in patients with viral infections and solid tumors
Cancer Immunotherapy Works Differently in Viral Infections
This narrative review synthesizes evidence on immune checkpoint inhibitors in patients with viral infections and solid tumors. It highlights…
Cancer immunotherapy can still work—and sometimes even control viruses like hepatitis or HIV—but doctors must watch for dangerous flare-ups.
Cadonilimab plus chemotherapy shows 72.5% ORR in 51 patients with cervical cancer.
New Cervical Cancer Drug Shrinks Tumors In Early Real World Tests
This prospective observational cohort study enrolled 51 patients with cervical cancer receiving cadonilimab (≥2 cycles) with chemotherapy, w…
A new cervical cancer drug shows promising results in early real-world tests, shrinking tumors for most patients while keeping side effects …
Narrative review suggests adjuvant pembrolizumab benefits selected high-risk renal cell carcinoma patients.
Old cancer drugs failed, but one new drug saves high-risk kidney patients today.
This narrative review evaluates adjuvant therapies for renal cell carcinoma, including cytokine-based immunotherapy, VEGF-targeted agents, a…
Doctors finally have a powerful new tool to stop kidney cancer from coming back after surgery, but it only works for specific patients.
Comprehensive review of ocular toxicity risks across all currently approved antibody-drug conjugates
Cancer drugs may harm your vision without warning
This comprehensive review synthesizes evidence regarding ocular toxicity associated with all currently approved antibody-drug conjugates (AD…
Popular cancer drugs can hurt your eyes, yet doctors often miss these side effects until vision suffers significantly.
Narrative review explores immunopathological framework for complicated intra-abdominal infection and intra-abdominal sepsis
Abdominal Infections Turn Deadly in Hours — Here’s Why
This narrative review examines the compartment-oriented immunopathological framework as a conceptual alternative to traditionally source con…
A hidden immune switch in the belly can trap infection — or unleash life-threatening sepsis, depending on timing and health
Systematic review on tertiary lymphoid structures in hepatocellular carcinoma
These immune clusters may predict liver cancer treatment success.
This systematic review synthesizes evidence on tertiary lymphoid structures in hepatocellular carcinoma. It describes their formation, class…
Tiny immune clusters found near liver tumors could help doctors predict if immunotherapy will save lives before treatment starts.