Intranasal ketamine shows similar pain relief to IV opioids for renal colic in ED meta-analysis
Intranasal ketamine and IV opioids show similar pain relief for kidney stones
A meta-analysis of 4 RCTs including 454 patients with renal colic found no significant differences in pain scores at 5, 15, or 30 minutes be…
Nasal ketamine and IV opioids provide equal pain relief for kidney stones, with no difference in side effects or need for extra medication.
Ketorolac shows early analgesic advantage for post-endodontic pain at 6 hours in meta-analysis
Which pain reliever works best after a root canal? Ketorolac may help most in the first 6 hours.
A systematic review and meta-analysis of 7 studies in patients undergoing root canal therapy found ketorolac provided statistically signific…
Ketorolac offers the best pain relief in the first six hours after a root canal, reducing the need for extra rescue doses compared to other …
Study Buddy Intervention Fails to Improve Retention in Rural PWUD Longitudinal Research
Study buddy approach did not improve retention in rural drug use research
A randomized controlled trial of 739 rural people who use drugs (PWUD) in the US found that adding a participant-referred 'study buddy' inte…
Asking rural people who use drugs to recruit a 'study buddy' did not improve their chances of staying in long-term health research compared …
Pain catastrophizing predicts tDCS response patterns in knee osteoarthritis pain
Why does brain stimulation help some knee pain patients but not others?
A secondary analysis of 60 participants with knee osteoarthritis from a randomized trial used machine learning to identify predictors of res…
Knee pain patients who fear their pain the most often fail to benefit from brain stimulation therapy, while those with lower initial pain le…
Anodal tDCS of left motor cortex reduces experimental thermal pain in healthy adults
Can a gentle brain zap turn down the dial on pain?
A triple-blind, randomized crossover trial in 50 healthy adults found anodal transcranial direct current stimulation (tDCS) of the left moto…
Gentle brain stimulation can significantly reduce pain in healthy adults, but the opposite type of stimulation actually made the pain feel w…
Mobilization with movement reduces pain and disability in knee osteoarthritis meta-analysis
Mobilization therapy shows promise for reducing knee osteoarthritis pain and disability
A meta-analysis of 2 RCTs in individuals with knee osteoarthritis found mobilization with movement (MWM) significantly reduced pain (Hedges'…
A hands-on therapy called mobilization with movement significantly reduced pain and improved daily function for people with knee osteoarthri…