High sFlt-1 levels correlate with increased PPCM risk in postpartum women
High sFlt-1 Levels Linked to Risk of Heart Failure
This meta-analysis evaluates the association between circulating sFlt-1 and peripartum cardiomyopathy (PPCM) risk. Findings indicate that hi…
New data shows a link between high sFlt-1 levels and heart muscle damage in women after giving birth, especially those with pre-eclampsia.
Bedtime antihypertensive dosing shows no cardiovascular benefit over morning dosing
Bedtime vs. Morning Blood Pressure Meds: No Clear Winner
A meta-analysis of randomized trials compared bedtime versus morning administration of antihypertensives. No evidence of a difference in maj…
Taking blood pressure medication at bedtime did not reduce heart attacks, strokes, or deaths more than morning dosing in a large analysis of…
Incidental arrhythmia findings on ambulatory ECG vary widely in adults without prior atrial fibrillation
Hidden heart rhythm problems found in up to 96% of adults
This systematic review and meta-analysis of 136,344 community-based adults without prior atrial fibrillation found that the prevalence of in…
A review of 136,344 adults found hidden heart rhythm issues in up to 96% of people without known atrial fibrillation.
Network meta-analysis reveals resistance training offers largest LVEF gains for adult heart failure patients compared to other exercise types
Resistance training shows greatest heart function boost in network analysis
A network meta-analysis of 3,519 adult heart failure patients found resistance training yielded the greatest improvement in left ventricular…
A network meta-analysis of 3,519 heart failure patients found resistance training improved heart function more than other exercise types, wi…
Microcirculatory dysfunction during cardiac surgery remains heterogeneous and inconclusive in current clinical evidence
Microcirculation in Cardiac Surgery: What We Know and What Remains Unclear
This narrative review examines microcirculatory dysfunction in patients undergoing cardiac surgery with cardiopulmonary bypass. The authors …
A review of cardiac surgery research shows mixed results on microcirculation, with many gaps between lab findings and patient care.
Conduction system pacing improves LVEF and reduces HF hospitalization vs biventricular pacing in heart failure
Conduction system pacing shows promise for heart failure patients
This systematic review and meta-analysis of 7,019 adult HF patients (LVEF ≤ 50%) found that conduction system pacing (CSP) was associated wi…
A meta-analysis of 7,019 heart failure patients suggests conduction system pacing may improve heart function and reduce hospitalizations com…
FDA Approves Furosemide for Edema and Hypertension
FDA approves furosemide to treat fluid buildup and high blood pressure.
The FDA approved furosemide for edema associated with congestive heart failure, cirrhosis, and renal disease, and for hypertension in adults…
The FDA has approved furosemide, a diuretic (water pill), to treat fluid retention in adults and children with heart failure, liver disease,…
Evolocumab reduces cardiovascular events in diabetes without known atherosclerosis
Evolocumab cuts heart events in high-risk diabetes patients
This prespecified subgroup analysis of a phase 3 RCT evaluated evolocumab added to statin therapy in 3655 high-risk patients with type 2 dia…
Adding evolocumab to statins reduced heart attacks and strokes by about 30% in high-risk diabetes patients without known heart disease.
Systematic review suggests modest risk reduction with SGLT2 inhibitors or ARNIs added to standard therapy in severe heart failure
Moderate evidence supports adding SGLT2 inhibitors to heart failure treatment
This systematic review and network meta-analysis evaluated adding SGLT2 inhibitors or angiotensin receptor-neprilysin inhibitors to neurohor…
A large analysis suggests adding SGLT2 inhibitors may lower risk of death or hospitalization for heart failure, though caution is advised.
HEART score sensitivity 0.96 vs GRACE 0.88 for 30-day MACE in ED chest pain
HEART score better than GRACE at spotting heart attack risk in emergency room patients
This systematic review and meta-analysis of 14,862 ED patients with acute chest pain compared the HEART and GRACE scores for predicting 30-d…
A large review shows the HEART score is better at finding people with heart attacks than the GRACE score, helping doctors safely discharge l…
Natriuresis-guided diuretic protocols improve fluid removal and shorten hospital stays for acute decompensated heart failure patients compared to standard care approaches in this meta-analysis review
Trial shows natriuresis-guided diuretics help heart failure patients
This systematic review and meta-analysis of 831 patients found that natriuresis-guided diuretic protocols significantly enhanced fluid remov…
A review of 831 patients finds that guiding diuretics by sodium output can increase urine output and shorten hospital stays for acute heart …
Laparoscopic hysteroscopic tubal lavage triggers cardiac arrest from torsade de pointes in a patient with acquired long QT syndrome
Laparoscopy linked to rare heart rhythm issue in one patient
This case report describes a 38-year-old female with acquired long QT syndrome who experienced cardiac arrest due to torsade de pointes afte…
A rare heart rhythm problem appeared after a common gynecologic surgery in a young woman. Her heart rate slowed and electrical signals stret…