This week's Diabetes & Endocrinology digest · 2026-W18
This Week in Diabetes & Endocrinology: Weight Loss Agents and Renal Outcomes
CPAP Most Effective for Apnea-Hypopnea Index, GLP-1 RAs Improve Weight in OSA
CPAP and weight-loss drugs show different benefits for sleep apnea patients
This network meta-analysis of 3964 adults with obstructive sleep apnea found that CPAP produced the largest reduction in apnea-hypopnea inde…
A large analysis found CPAP best for breathing control, while weight-loss drugs improved body weight and blood sugar levels in sleep apnea p…
Ecnoglutide Reduces HbA1c and Body Weight in Type 2 Diabetes: Meta-Analysis
New diabetes drug cuts sugar and weight in adults with Type 2 Diabetes
A meta-analysis of 1643 adults with type 2 diabetes found that ecnoglutide significantly reduced HbA1c (MD -0.44, 95% CI -0.55 to -0.33) and…
A large review shows ecnoglutide lowers blood sugar and body weight in adults with Type 2 Diabetes. It also has an acceptable safety profile…
SMS Text Messaging Lifestyle Programs Show No Significant Benefit for Prediabetes
SMS lifestyle programs show no clear benefit for prediabetes outcomes in this meta-analysis
This systematic review and meta-analysis of 4632 adults with prediabetes found that SMS text messaging-delivered lifestyle programs did not …
A large review of text message health programs found no significant improvement in weight or diabetes risk for adults with prediabetes.
Reversion of Prediabetes to Normoglycemia Linked to 68% Lower Diabetes Risk
Reversing prediabetes cuts diabetes risk by 68 percent in a massive study
A meta-analysis of 535,066 participants with prediabetes found that reversion to normoglycemia was associated with a 68% lower risk of incid…
Reversing prediabetes to normal blood sugar levels lowers the risk of developing diabetes by 68 percent in people with the condition.
Intensive lifestyle intervention improves health-related quality of life in patients with obesity
Greater weight loss linked to better quality of life in obesity patients
This randomized controlled trial enrolled 803 patients with obesity across eighteen primary care clinics. Participants received a 24-month i…
A large trial shows that losing more weight is associated with better quality of life, though some racial differences were noted.
Systematic review and meta-analysis finds elevated magnetic sphincter augmentation erosion after sleeve gastrectomy
Magnetic sphincter augmentation erosion risk is higher after sleeve gastrectomy
This systematic review and meta-analysis of 287 patients found that magnetic sphincter augmentation (MSA) erosion after laparoscopic sleeve …
A meta-analysis shows patients with sleeve gastrectomy have a higher erosion rate after magnetic sphincter augmentation compared to nonbaria…
Meta-analysis: Postoperative oral antibiotics reduce cellulitis after cesarean in obese women
Adding two antibiotics may lower cellulitis risk for obese women having C-sections
This systematic review and meta-analysis of 1144 obese women undergoing cesarean delivery found that adding postoperative oral cephalexin an…
A large review found adding oral cephalexin and metronidazole to standard care significantly reduced cellulitis in obese women after C-secti…
A 1-month nudge-based dietary intervention increased daily step counts by 1105 steps at 3 months in adults with type 2 diabetes.
Small diet changes might boost steps for a short time in diabetes care
This cluster-randomised controlled trial enrolled 204 adults aged 18-59 years with type 2 diabetes across 12 primary healthcare centres in B…
A simple diet plan helped people with diabetes walk more for three months but the extra steps did not stick in the long run
Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
Oral sodium butyrate helps overweight adults without diabetes lose weight
This 12-week proof-of-concept RCT in 46 overweight adults (23 with type 2 diabetes) found that oral sodium butyrate 1875 mg/day led to great…
A new trial shows oral sodium butyrate helps adults without diabetes lose more weight than a placebo over three months.
Network meta-analysis suggests tirzepatide and surgery improve MASH resolution versus standard care in adults with obesity
Weight-loss drugs and surgery may clear fatty liver disease in adults with high BMI
This systematic review and network meta-analysis evaluates interventions for metabolic dysfunction-associated steatotic liver disease and st…
A new analysis suggests tirzepatide, semaglutide, and surgery might help resolve fatty liver disease without worsening scarring in adults wi…
Meta-analysis finds GLP-1RA plus SGLT2i reduces UACR in type 2 diabetes with kidney disease
Combining two diabetes drugs protects kidneys better than using just one alone
This systematic review and meta-analysis of 1974 adults with type 2 diabetes and diabetic kidney disease found that combination therapy with…
Combining two common diabetes drugs offers better kidney protection than taking just one alone for people with type 2 diabetes
Systematic review and meta-analysis shows small BMI reduction in preschoolers with screen-time interventions
Screen-time programs slightly lower BMI in preschoolers but diet habits stay the same
This systematic review and meta-analysis evaluated screen-time-focused interventions for preschool children aged 2 to 6 years. Approximately…
A review of 2800 preschoolers found small BMI drops with screen-time limits, yet diet behaviors showed no consistent improvement.