NTIS subtypes and thyroid antibodies associated with higher in-hospital mortality in sepsis cohort
Thyroid Antibodies Signal Higher Death Risk in Sepsis
A retrospective cohort study of 871 sepsis patients at a Shanghai tertiary hospital found non-thyroidal illness syndrome (NTIS) was independ…
Thyroid antibodies found in sepsis patients signal a higher risk of death, offering doctors a critical warning sign beyond standard infectio…
Neighborhood Socioenvironmental Burden Associated with Pre-Transplant Variables in Liver Transplant Recipients
Your Neighborhood Could Be Shaping Your Transplant Journey
A single-center retrospective analysis of 2,030 liver transplant recipients in Houston found that a higher Environmental Justice Index score…
Where you live may not determine your transplant outcome, but it can spotlight the extra hurdles you face getting to the operating room.
Higher TG/HDL-C ratio associated with lower BMD in older adults at high elevation
High Altitude Fat Ratio Linked to Weaker Bones
This retrospective cross-sectional study evaluated 650 older adults residing in high-elevation regions. It assessed the association between …
A specific fat ratio in your blood may signal weaker bones for seniors living high up.
FDA Approves Dapagliflozin Tablets (dapagliflozin) for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
FDA approves a diabetes drug that also helps protect the heart in certain adults.
The FDA has approved dapagliflozin tablets to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and establ…
A new diabetes tablet now helps control blood sugar while also lowering the risk of heart failure hospitalization for adults with heart dise…
FDA Approves Dapagliflozin Tablets (dapagliflozin) for Type 2 Diabetes and Heart Failure Risk Reduction
FDA approves a new pill for type 2 diabetes that also helps protect the heart.
The FDA has approved dapagliflozin tablets for two indications in adults with type 2 diabetes mellitus: to improve glycemic control and to r…
A new FDA-approved pill for type 2 diabetes now helps lower blood sugar while also reducing the risk of hospitalization for heart failure.
FDA Approves Dapagliflozin and Metformin Hydrochloride Extended-Release Tablets for Type 2 Diabetes and Related Risks
FDA approves a new once-daily pill for type 2 diabetes that may also help protect the heart and kidneys.
The FDA has approved dapagliflozin and metformin hydrochloride extended-release tablets as an adjunct to diet and exercise to improve glycem…
A new once-daily pill for type 2 diabetes may protect the heart and kidneys from serious problems like heart attacks and worsening kidney di…
PPARα rs6008845 genotype modifies fenofibrate benefit for vascular events in type 2 diabetes
Genetic variant linked to diabetes risks and fenofibrate benefits in FIELD study
This RCT substudy of 8,159 adults with type 2 diabetes examined the PPARα rs6008845 genotype and fenofibrate treatment. Participants carryin…
A specific gene variant increases diabetes complication risks, but fenofibrate treatment benefits remain consistent across all genetic group…
Meta-analysis finds 23% subthreshold depression prevalence in patients with diabetes mellitus
Subthreshold depression affects about one in four people with diabetes mellitus
A systematic review and meta-analysis of 33 studies including 255,371 patients with diabetes found a pooled prevalence of subthreshold depre…
About one in four people with diabetes has subthreshold depression, a condition that raises complication risks and lowers quality of life wi…
Systemic inflammation mediates links between sleep, obesity, and musculoskeletal pain but not consistently for psychological factors.
Systemic inflammation links sleep and obesity to pain, but psychological factors differ
This systematic review analyzed twenty-one articles examining systemic inflammation as a mediator between lifestyle or psychological factors…
Systemic inflammation connects sleep problems and obesity to pain, but psychological factors appear to interact differently rather than acti…
Systematic review of 2025 RCTs identifies new standards of care across genitourinary cancers
New standards of care established for bladder, kidney, prostate, testicular, and penile cancers in 2025.
A systematic review and meta-analysis of 40 phase II/III RCTs in patients with bladder, kidney, prostate, testicular, and penile cancers fou…
New 2025 standards of care for bladder, kidney, prostate, testicular, and penile cancers now emphasize biomarker-driven strategies and immun…
Extended overnight fasting improves nighttime blood pressure dipping in overweight/obese adults
Extended overnight fasting improved nighttime blood pressure dipping in a small group of overweight adults.
A randomized parallel-arm controlled trial in 39 overweight/obese participants (36-75 years) found that extended overnight fasting (13-16 ho…
Overnight fasting until three hours before sleep improved nighttime blood pressure dipping and heart rate in overweight adults.
NoSAS score diagnostic accuracy for obstructive sleep apnea screening
NoSAS score shows mixed accuracy for screening obstructive sleep apnea across severity levels
This systematic review and meta-analysis evaluated the diagnostic accuracy of the Neck Circumference, Obesity, Snoring, Age, and Sex (NoSAS)…
The NoSAS score misses many severe sleep apnea cases, catching only 82% of them while failing to rule out half of those without the conditio…