Single-cell sequencing reveals T cell clonal patterns in healthy donors and ulcerative colitis patients
T Cells Move Freely in Colon, Not Just in Blood
This observational study analyzed 333,088 T cells from healthy donors and ulcerative colitis (UC) patients using single-cell T cell receptor…
T cells in the colon travel freely across the gut, not just in the blood, reshaping how we understand immune health in conditions like ulcer…
Meta-analysis finds exercise training reduces intrahepatic lipids and improves metabolic markers in NAFLD
Which Workout Melts Liver Fat Fastest? New Rankings Are In
A systematic review and meta-analysis of 1,880 adults with NAFLD found exercise training significantly reduced intrahepatic lipids (SMD: -0.…
A fresh look at 38 trials shows exercise reliably trims liver fat and improves blood sugar, with HIIT leading the pack.
Hepatitis E vaccine linked to elevated spontaneous abortion risk when given 31-60 days before pregnancy
A Vaccine's Hidden Risk Window for Early Pregnancy Loss
An RCT in women vaccinated during or shortly before pregnancy found an elevated risk of spontaneous abortion (Relative Risk 4.3) in HEV239 r…
A Hepatitis E vaccine given one to two months before pregnancy is linked to a higher risk of miscarriage, forcing doctors to rethink timing …
Blood group B alleles associated with increased MIS-C risk in Italian children cohort study
Why Blood Type B May Raise One Rare COVID Risk in Kids
A cohort study of 18 Italian children with MIS-C or Kawasaki-like disease found blood group B alleles conferred increased risk (OR 2.9).
A small study suggests that blood type and inherited immune differences may help explain which children get the rare post-COVID inflammatory…
Machine learning models show moderate to high accuracy for predicting variceal bleeding in cirrhosis patients
New AI Tool Catches Bleeding Risks Early
A systematic review and meta-analysis of 21 studies involving 7,011 cirrhosis patients found machine learning models achieved pooled c-indic…
An AI tool now spots bleeding risks in liver disease earlier than current methods, helping doctors catch dangerous vein swelling before it t…
SBRT plus PD-1 inhibitor and lenvatinib improved PFS in oligoprogressive HCC patients
Radiation Plus Immune Drugs Stops Liver Cancer Growth
This prospective Phase 2 study evaluated stereotactic body radiation therapy (SBRT) combined with continued first-line PD-1 inhibitor-based …
Combining targeted radiation with ongoing immune therapy can restart cancer control in patients whose disease was slowly spreading again.
Phase 2 trial of JNJ-73763989-based regimen shows no HBsAg seroclearance at primary endpoint in HBeAg-positive CHB
New combo lowers hepatitis B virus levels
A phase 2 trial in 54 treatment-naïve, HBeAg-positive chronic hepatitis B patients tested a regimen of JNJ-73763989 ± bersacapavir with nucl…
A new drug combination successfully lowered virus levels in many patients, though clearing the virus completely happened in only about one o…
Vitamin D supplementation associated with improved metabolic markers in patients with Metabolic-Associated Fatty Liver Disease
A Simple Vitamin May Help Your Body Manage a Fatty Liver
This systematic review and meta-analysis evaluated 21 studies involving patients with Metabolic-Associated Fatty Liver Disease (MAFLD) recei…
Vitamin D supplements improved blood sugar, cholesterol, and liver health in people with fatty liver disease, offering a simple add-on to he…
Wearable monitoring characterizes autonomic dysfunction in hypermobile Ehlers-Danlos syndrome compared to healthy controls
Wearable Watch Could End Years of Waiting for hEDS Diagnosis
This prospective cohort study enrolled 30 individuals with hypermobile Ehlers-Danlos syndrome (hEDS) and 28 healthy controls.
A smartwatch can spot the hidden physical changes of hypermobile Ehlers-Danlos Syndrome (hEDS) much faster than current methods.
Nurse-assisted outpatient follow-up reduces 30-day readmissions but not mortality in decompensated cirrhosis
Nurse Care Cuts Hospital Returns for Liver Patients
A meta-analysis of 668 patients with decompensated liver cirrhosis found nurse-assisted outpatient follow-up significantly reduced 30-day re…
Adding nurses to liver care teams significantly cuts 30-day hospital readmissions and improves outcomes for patients with advanced liver dis…
Laparoscopic hemihepatectomy shows higher costs but better QALYs than open approach in European trial
Laparoscopic surgery costs more upfront but may offer better value for some liver patients
A phase 3 randomized controlled trial of 332 patients undergoing hemihepatectomy at 16 European centers found laparoscopic surgery had highe…
Laparoscopic liver surgery costs more upfront but delivers better long-term value and quality of life for patients.
Network meta-analysis finds pegozafermin, OCA, and resmetirom outperform placebo for MASLD fibrosis improvement
New Liver Treatments Show Real Promise in Reversing Scarring
A systematic review and network meta-analysis of 10,119 adult patients with MASLD found pegozafermin, obeticholic acid (OCA), and resmetirom…
For the first time, doctors have clear evidence that new medications can help reverse the dangerous liver scarring caused by common fatty li…