Rituximab exposure is associated with serum sickness in patients with multiple sclerosis, nephrotic syndrome, or immune thrombocytopenia.
Can taking Rituximab cause a severe allergic reaction that returns if you take it again?
This retrospective review analyzed 39 published case reports of patients with rituximab-induced serum sickness (RISS). The study describes c…
Taking Rituximab can trigger a delayed allergic reaction that returns in most patients if the drug is given again, so doctors must use extre…
Phase I trial of regorafenib plus ipilimumab and nivolumab shows 27.6% response in MSS colorectal cancer
Who Really Responds to a Stubborn Colon Cancer Combo?
A phase I trial in 29 patients with microsatellite-stable metastatic colorectal cancer tested the combination of regorafenib, ipilimumab, an…
A three-drug combo helped some patients with stubborn colon cancer, and immune markers now predict who will benefit most.
Single-cell sequencing reveals T cell clonal patterns in healthy donors and ulcerative colitis patients.
T Cells Move Freely in Colon, Not Just in Blood
This observational study analyzed 333,088 T cells from healthy donors and ulcerative colitis (UC) patients using single-cell T cell receptor…
T cells in the colon travel freely across the gut, not just in the blood, reshaping how we understand immune health in conditions like ulcer…
Meta-analysis finds exercise training reduces intrahepatic lipids and improves metabolic markers in NAFLD
Which Workout Melts Liver Fat Fastest? New Rankings Are In
A systematic review and meta-analysis of 1,880 adults with NAFLD found exercise training significantly reduced intrahepatic lipids (SMD: -0.…
A fresh look at 38 trials shows exercise reliably trims liver fat and improves blood sugar, with HIIT leading the pack.
Hepatitis E vaccine linked to elevated spontaneous abortion risk when given 31-60 days before pregnancy
A Vaccine's Hidden Risk Window for Early Pregnancy Loss
An RCT in women vaccinated during or shortly before pregnancy found an elevated risk of spontaneous abortion (Relative Risk 4.3) in HEV239 r…
A Hepatitis E vaccine given one to two months before pregnancy is linked to a higher risk of miscarriage, forcing doctors to rethink timing …
Blood group B alleles associated with increased MIS-C risk in Italian children cohort study
Why Blood Type B May Raise One Rare COVID Risk in Kids
A cohort study of 18 Italian children with MIS-C or Kawasaki-like disease found blood group B alleles conferred increased risk (OR 2.9). All…
A small study suggests that blood type and inherited immune differences may help explain which children get the rare post-COVID inflammatory…
Machine learning models show moderate to high accuracy for predicting variceal bleeding in cirrhosis patients
New AI Tool Catches Bleeding Risks Early
A systematic review and meta-analysis of 21 studies involving 7,011 cirrhosis patients found machine learning models achieved pooled c-indic…
An AI tool now spots bleeding risks in liver disease earlier than current methods, helping doctors catch dangerous vein swelling before it t…
SBRT plus PD-1 inhibitor and lenvatinib improved PFS in oligoprogressive HCC patients.
Radiation Plus Immune Drugs Stops Liver Cancer Growth
This prospective Phase 2 study evaluated stereotactic body radiation therapy (SBRT) combined with continued first-line PD-1 inhibitor-based …
Combining targeted radiation with ongoing immune therapy can restart cancer control in patients whose disease was slowly spreading again.
Phase 2 trial of JNJ-73763989-based regimen shows no HBsAg seroclearance at primary endpoint in HBeAg-positive CHB
New combo lowers hepatitis B virus levels
A phase 2 trial in 54 treatment-naïve, HBeAg-positive chronic hepatitis B patients tested a regimen of JNJ-73763989 ± bersacapavir with nucl…
A new drug combination successfully lowered virus levels in many patients, though clearing the virus completely happened in only about one o…
Vitamin D supplementation associated with improved metabolic markers in patients with Metabolic-Associated Fatty Liver Disease.
A Simple Vitamin May Help Your Body Manage a Fatty Liver
This systematic review and meta-analysis evaluated 21 studies involving patients with Metabolic-Associated Fatty Liver Disease (MAFLD) recei…
Vitamin D supplements improved blood sugar, cholesterol, and liver health in people with fatty liver disease, offering a simple add-on to he…
Wearable monitoring characterizes autonomic dysfunction in hypermobile Ehlers-Danlos syndrome compared to healthy controls.
Wearable Watch Could End Years of Waiting for hEDS Diagnosis
This prospective cohort study enrolled 30 individuals with hypermobile Ehlers-Danlos syndrome (hEDS) and 28 healthy controls. Participants w…
A smartwatch can spot the hidden physical changes of hypermobile Ehlers-Danlos Syndrome (hEDS) much faster than current methods.
Nurse-assisted outpatient follow-up reduces 30-day readmissions but not mortality in decompensated cirrhosis
Nurse Care Cuts Hospital Returns for Liver Patients
A meta-analysis of 668 patients with decompensated liver cirrhosis found nurse-assisted outpatient follow-up significantly reduced 30-day re…
Adding nurses to liver care teams significantly cuts 30-day hospital readmissions and improves outcomes for patients with advanced liver dis…