Review examines reference gene selection methods for qRT-PCR normalization in cancer research
Review examines gene analysis methods for cancer research and precision medicine
A systematic review describes the progression of traditional and advanced reference gene selection methods for qRT-PCR normalization and the…
Accurate cancer research depends on picking the right reference genes, and new tools now help scientists choose them for better precision me…
Combined tumor markers and CT imaging show high sensitivity for solitary pulmonary nodule malignancy
Study finds combining blood tests and CT scans may help assess lung nodule cancer risk
A retrospective cohort study of 110 patients with solitary pulmonary nodules found that combining serum tumor markers (CEA, NSE, CA-125, CYF…
Combining blood tests and CT scans correctly identified 96.9% of cancerous lung nodules, outperforming either test alone in spotting maligna…
Prime editing therapy shows early neutrophil activity in two patients with p47-deficient CGD
Early trial shows gene editing therapy may restore immune function in two patients with rare disease
A Phase 1 trial in two participants with p47-deficient chronic granulomatous disease (CGD) found that autologous CD34+ cell therapy using pr…
Two patients with a rare immune disorder regained the ability to fight infections after receiving a new gene editing therapy that fixed thei…
Extended goal-directed fluid therapy shows no benefit for complications after esophagectomy in single-center trial
Does personalized fluid therapy after esophageal cancer surgery reduce complications?
A single-center, single-blind RCT of 100 patients undergoing esophagectomy found that extended, individualized goal-directed fluid therapy d…
Personalized fluid therapy after esophageal cancer surgery did not reduce complications, despite higher fluid intake and medication use in p…
Meta-analysis identifies two genomic loci associated with antidepressant non-response in 135,471 individuals
Why do antidepressants fail for some people? New genetic clues emerge
A genome-wide association meta-analysis of 135,471 individuals prescribed antidepressants identified two novel genomic loci associated with …
Millions struggle to find working antidepressants, but new genetic data reveals why some fail and suggests other drug options for treatment …