Review of solitary plasmacytoma radiotherapy outcomes in Indian tertiary care
Rare Bone Tumor Treatment Shows Long-Term Success with Radiotherapy
This retrospective audit review from a tertiary care center in eastern India summarizes outcomes for 46 patients with solitary plasmacytoma …
A new look at real-world patients shows radiation therapy can control this rare cancer for over nine years.
Observational study identifies PF4-dependent antibodies in ELISA-negative HIT patients via functional testing
Could stopping blood thinners because of a false negative test actually harm you?
This observational research article with an animal component evaluates PF4-dependent platelet-activating antibodies in ELISA-negative patien…
Standard blood tests for a dangerous clotting disorder missed six patients, leading doctors to stop life-saving medicine and causing new clo…
AMH Levels in Pediatric Cancer Patients Before and After Treatment
Could a simple blood test tell you if cancer treatment will hurt your future fertility?
This prospective cohort study evaluated anti-mullerian hormone (AMH) levels in 74 girls with pediatric cancer. Age-adjusted AMH was 79% lowe…
A simple blood test measuring egg counts drops 79% after cancer treatment, offering early warning for young girls facing chemotherapy.
FDA Approves Rytelo (telomerase inhibitor oligonucleotide) for transfusion-dependent anemia in low- to intermediate-1 risk MDS
FDA approves new drug called Rytelo for certain blood disorder patients who need frequent transfusions.
Rytelo is approved for adult patients with low- to intermediate-1 risk myelodysplastic syndromes (MDS) who have transfusion-dependent anemia…
FDA approves Rytelo to help adults with low-risk blood disorders who need frequent transfusions after other treatments fail.
Meta-analysis finds non-clotting factor therapies reduce bleeding in congenital hemophilia
Can new therapies help people with hemophilia bleed less and live better?
This meta-analysis of 6 RCTs (397 participants) synthesizes evidence on non-clotting factor therapies for bleed prevention in congenital hem…
For people with hemophilia, frequent bleeding can disrupt daily life and cause pain. A review of studies suggests that newer preventive ther…
Ianalumab plus eltrombopag extends time to treatment failure in primary ITP adults.
Study tests ianalumab plus eltrombopag for adults with immune thrombocytopenia
This phase 3 randomized, double-blind trial in 152 adults with primary ITP and insufficient response to glucocorticoids found that ianalumab…
Adding ianalumab to standard therapy helped more adults with immune thrombocytopenia stay stable and avoid treatment failure compared to pla…
Phase 2 trial tests single-dose IV iron isomaltoside in severe aortic stenosis with iron deficiency
Early study suggests iron treatment may help heart function in severe aortic stenosis patients.
This Phase 2, double-blind, randomized, placebo-controlled trial tested a single intravenous dose of iron isomaltoside versus placebo in pat…
Treating iron deficiency may improve exercise capacity and reduce fatigue in people with severe aortic stenosis, according to early trial re…
Meta-analysis of HSCT with treosulfan in Ataxia Telangiectasia patients shows mixed survival outcomes and significant toxicities.
A Teen With a Rare Disease Beat Leukemia After a Risky Transplant
This systematic review and meta-analysis evaluated hematopoietic stem cell transplantation (HSCT) using treosulfan in 16 patients with Ataxi…
A 16-year-old with a rare genetic disease survived leukemia after a tailored stem cell transplant, offering new hope for others with this fr…
BR regimen shows survival outcomes in newly diagnosed Waldenstroms Macroglobulinemia patients
A Rare Blood Cancer With an 8-Year Survival: What Real-World Data Shows
This single-center retrospective analysis evaluated 89 newly diagnosed Waldenstroms Macroglobulinemia patients treated with the BR regimen. …
New real-world data shows patients with the rare blood cancer Waldenstrom's macroglobulinemia live a median of over 8 years after diagnosis.
Biomarkers and clinical factors show statistical associations with sepsis-induced coagulopathy in 37,459 patients.
Your Blood May Signal a Deadly Clotting Crisis Before It Strikes
This systematic review and meta-analysis evaluated 37,459 patients to assess the association between various biomarkers and clinical factors…
Blood markers like glycocalyx degradation and low fibrinogen can predict deadly clotting in sepsis patients early, potentially saving lives …
Interim FDG PET predicts outcomes in large B-cell lymphoma, with DS 5 indicating highest risk.
Mid-Treatment Scan Predicts Lymphoma Outcomes Better Than Expected
A meta-analysis of 44 studies in large B-cell lymphoma patients found that interim FDG PET (iPET) had sensitivity of 0.78 and specificity of…
A PET scan halfway through lymphoma treatment predicts survival outcomes with striking accuracy, offering a powerful tool to personalize car…
Systematic review validates iPSC-derived organoids as models for ALS pathology compared to traditional 2D or animal models.
Scientists Grow Tiny ALS Brains in Labs — What It Could Mean
This systematic review evaluated in vitro organoid models derived from human-specific neural and neuromuscular subtypes for Amyotrophic Late…
For the first time, scientists can watch ALS unfold in human tissue grown outside the body — which could speed up the search for treatments …