Modelling analysis review estimates TB cases and deaths averted by screening in ten Asian countries.
A $12 Billion Plan to Save Millions from Tuberculosis
This modelling analysis review evaluates the epidemiological impact and cost implications of scaling up tuberculosis screening across ten hi…
AI scans in communities could save millions of lives by finding silent tuberculosis cases in ten high-risk Asian countries before they sprea…
Observational cohort study on SARS-CoV-2 evolution in immunocompromised patients
Long COVID Virus Changes Shape Inside Severely Ill Patients, Study Finds
This observational cohort study analyzed longitudinal SARS-CoV-2 genomes from 91 immunocompromised patients with COVID-19. It found that sev…
When the virus lingers too long in very sick patients, it changes in unpredictable ways, highlighting the need for stronger treatments.
Observational serological model in Malawi shows rapid SARS-CoV-2 antibody waning and urban-rural differences
Malawi Study Rewrites Rules of COVID Immunity
This observational study used serological modelling to reconstruct SARS-CoV-2 infection histories in unvaccinated Malawian adults. It found …
In Malawi, natural immunity fades fast, with antibodies dropping to 5% after one year, so vaccines remain essential for lasting protection.
Selective Decontamination of the Digestive Tract showed no mortality benefit over standard care in mechanically ventilated patients.
A Common ICU Infection Strategy Fails Its Biggest Test
This randomized trial involving 9,289 critically ill patients across 26 ICUs in Australia and Canada evaluated Selective Decontamination of …
A massive ICU trial found that wiping out gut bacteria in ventilated patients reduced infections but did not save more lives.
Narrative review explores psychobiotics and lifestyle changes for chronic constipation-depression comorbidity
Your Gut and Your Mood Are Talking — Here's What They're Saying
This narrative review examines potential strategies for managing chronic constipation and depression comorbidity, including psychobiotics, f…
Chronic constipation and depression often share a common cause: gut bacteria imbalances that disrupt the signals between your digestive syst…
Narrative review explores links between antibiotic exposure and obesity or metabolic phenotypes
Your Gut Bacteria Remember Every Antibiotic You've Ever Taken
This narrative review examines potential associations between antibiotic exposure and obesity or metabolic phenotypes. The authors discuss v…
Antibiotics may alter your gut bacteria for months or years, potentially raising obesity risk, especially if taken early in life.
Narrative review examines lung microbiome and mucosal IgA in chronic inflammatory lung diseases
Your Lungs Have Their Own Microbiome — and It Affects Your Immune Defenses
This narrative review explores the interplay between the lung microbiome and mucosal immunoglobulin A system in chronic inflammatory lung di…
The lung's microbiome and immune protein IgA work together to protect health, and their breakdown drives chronic lung diseases like asthma a…
Adjuvanted RSV vaccine shows efficacy against RSV disease in older adults with comorbidities
One RSV Shot Protects High-Risk Older Adults for Three Full Seasons
This post-hoc analysis of a phase 3 trial evaluated an adjuvanted RSVPreF3 dose in medically stable adults aged 60 and older with underlying…
One RSV shot cuts illness risk by 63% to 75% for older adults with COPD, asthma, diabetes, or obesity over three full seasons.
Phase Ia trial of RH5.1 protein with Matrix-M adjuvant in malaria-naive UK adults showed safety and similar immunogenicity across two booster regimens.
A Malaria Vaccine Candidate Holds Strong — Even With a Smaller Booster Dose
This Phase Ia clinical trial evaluated the safety and immunogenicity of RH5.1 soluble protein with Matrix-M adjuvant in malaria-naive UK adu…
A malaria vaccine candidate produced strong immune responses even when the final booster dose was cut in half, potentially helping extend va…
Random forest model predicts pediatric varicella encephalitis with excellent performance in a retrospective analysis.
A Simple Checklist Could Catch the Most Dangerous Chickenpox Complication Early
This retrospective analysis evaluated a random forest model for predicting pediatric varicella encephalitis in 201 children. The model demon…
A new AI tool predicts dangerous chickenpox brain complications in kids with 95% accuracy using just six simple symptoms like rash duration …
Monoclonal stool antigen test shows high accuracy for H. pylori detection in chronic atrophic gastritis patients.
A Simple Stool Test Spots a Dangerous Stomach Bug Without a Scope
This prospective primary care study evaluated 287 patients with chronic atrophic gastritis (CAG) using a monoclonal stool antigen test (SAT)…
A simple stool test spots dangerous stomach bugs in people with chronic gastritis, performing even better when the stomach is most at risk.
EBNA1 SeroStrip-HT shows high accuracy for nasopharyngeal carcinoma risk assessment in a nested case-control study.
A Blood Test May Spot a Rare Cancer Years Before Symptoms Appear
This nested case-control study evaluated the EBNA1 SeroStrip-HT in prospective cohorts from Singapore and Shanghai, China. Among 20 pre-diag…
A simple blood test can spot a rare throat cancer up to four years before symptoms appear, giving doctors time to treat it early.