Serum cutoff values for MPXV antigens established in a DRC cohort of 134 individuals.
How Scientists Are Learning to Read Mpox Immunity in the Hardest-Hit Places
This cohort study of 134 individuals in the Democratic Republic of the Congo established antigen-specific serological cutoff values to diffe…
A new three-antigen blood test can identify past mpox infections in Central Africa, helping track immunity in the hardest-hit regions.
Hypervirulent Klebsiella pneumoniae linked to higher abscess risk and longer hospital stays in bloodstream infections
The "Super" Bacteria Causing Hospital Infections Doctors Struggle to Clear
A retrospective cohort study of 207 K. pneumoniae bloodstream infection episodes at a Japanese tertiary hospital found that hypervirulent st…
A specific aggressive form of hospital bacteria causes abscesses in patients six times more often than the common strain and doubles their h…
Methodological review assesses phenotypes for classifying respiratory viruses in English health data
How Doctors Track RSV, Flu, and COVID When Tests Aren't Always Done
This methodological review evaluates phenotypes for classifying respiratory viruses like RSV, influenza, and COVID-19 in English coded healt…
Coded health records can now identify RSV, flu, and COVID-19 outbreaks without lab tests, helping public health agencies track disease trend…
Cross-sectional study in South Benin finds metronidazole prescribing linked to symptoms
A Common Antibiotic Is Being Widely Prescribed — but Is It Always the Right Call?
A register-based cross-sectional study of 2,200 medical visits in South Benin primary care found metronidazole prescribing was associated wi…
In Benin, a common gut infection antibiotic is prescribed in nearly one in five clinic visits, raising urgent questions about whether it is …
Review describes scalable testing workflow for emerging infectious diseases
Frequent Testing Beat Lockdowns at Stopping Viral Spread
This after-action report review synthesizes a scalable workflow for specimen collection, analysis, and reporting during the COVID-19 pandemi…
Frequent testing with same-day results stopped viral spread better than lockdowns, proving rapid monitoring protects communities when new vi…
Review of WGS-enabled IPC surveillance for CPE transmission in a London hospital trust
Hospital Superbugs Are Spreading Undetected — and a DNA Tool Is Changing That
This retrospective review evaluated WGS-enabled infection prevention and control surveillance in a large tertiary care hospital trust in Lon…
Hospitals miss most dangerous germ transmissions, but a new DNA tool detects outbreaks up to 47 days earlier and saves millions annually.
Development and validation study of TranScrub qPCR assay for scrub typhus diagnosis
A Deadly Fever Is Being Missed Worldwide — A New Test May Finally Catch It
This primary research article describes the development and validation of the TranScrub qPCR assay for diagnosing scrub typhus in patients w…
A new genetic test catches scrub typhus with 91% accuracy, helping doctors diagnose this deadly fever that often mimics other illnesses and …
Review of genomic surveillance finds concurrent Mpox subclade circulation across Africa
Mpox Is Spreading in Ways Scientists Didn't See Coming
This review synthesizes genomic surveillance data from 24 African Union Member States, covering 3,450 high-quality MPXV virus whole genomes.…
Mpox is spreading across Africa in surprising ways, with different strains jumping from animals to people or spreading quietly between human…
Narrative review on sepsis and the microbiome, highlighting unresolved causality and variability.
Could your sepsis treatment be missing a key clue about your unique biology?
This narrative review synthesizes current evidence on the microbiome in sepsis. The authors highlight unresolved causality, inter-individual…
Sepsis treatment risks vary by biology because gut bacteria and genes drive inflammation, yet doctors currently lack tools to predict who wi…
Phase 1 cohort study assesses prophylactic pDNA vaccine safety and immunogenicity in healthy adults.
Early study of a COVID-19 DNA vaccine in healthy adults showed no serious safety issues.
This Phase 1 cohort study enrolled 42 eligible healthy subjects to evaluate a prophylactic COVID-19 pDNA vaccine compared to placebo (Saline…
A new COVID-19 DNA vaccine showed no serious safety issues in healthy adults after six months of monitoring.
MAIT cell frequency decreased in sepsis-related liver injury, with altered phenotype and function in murine models
Liver cells get help from immune defenders during sepsis
This observational cohort study in patients with sepsis-related liver injury (SRLI) and murine models found significantly decreased peripher…
During sepsis, immune defenders actually protect the liver instead of causing damage, offering new hope for patients losing liver function.
Biofilm-driven chronic rhinosinusitis: review reframes recalcitrance as immune and ecological dysregulation
A narrative review discusses chronic rhinosinusitis without reporting new study data or results.
This narrative review reframes treatment-recalcitrant chronic rhinosinusitis (CRS) as a biofilm-driven disorder in which microbial communiti…
This document is a narrative review about chronic rhinosinusitis, a condition involving long-term inflammation of the nasal sinuses. It does…