Review of Spatial AI combining multi-omics with deep learning for cancer biomarkers
Can AI read the hidden maps of cancer cells to find new ways to fight disease?
This narrative review examines the application of Spatial AI, specifically combining high-resolution spatial multi-omics with deep learning …
Cancer resistance hides in cell neighborhoods, not just individual cells, so new AI maps reveal how tumors organize defenses to block treatm…
tNGS in pediatric LRTIs shows higher Mycoplasma pneumoniae detection in severe vs non-severe CAP
A new test found more germs in severe pediatric pneumonia cases than mild ones.
A retrospective, single-center cohort study of 2,299 children with suspected lower respiratory tract infections found that targeted next-gen…
A new test found that severe pediatric pneumonia cases carry more germs than mild ones, revealing a link between specific microbial signatur…
Insulin administration associated with lower 28-day mortality in non-diabetic sepsis patients.
Insulin Might Help Sepsis Patients Survive Longer
This retrospective cohort study of 11,289 non-diabetic patients with sepsis found insulin administration was associated with reduced 28-day …
Insulin therapy was linked to a 37% lower risk of death in non-diabetic sepsis patients, though it extended hospital stays.
Plasma hyaluronic acid levels predict ARDS and intubation in adult COVID-19 patients.
Could a simple blood test help predict who needs breathing support for COVID-19?
This retrospective single-center cohort study evaluated plasma hyaluronic acid (HA) levels in 502 adult patients with COVID-19. HA demonstra…
High levels of a specific blood substance linked to severe lung trouble could help doctors spot who needs breathing support for COVID-19 soo…
Machine learning model aids early risk stratification for carbapenem-resistant Pseudomonas aeruginosa infection.
New tool helps identify resistant bacteria early in hospital patients
This retrospective cohort study evaluated a clinico-laboratory machine-learning model based on routine complete blood count parameters in pa…
A new tool uses routine blood tests to predict dangerous antibiotic resistance in hospital patients before final lab results arrive.
Whole-genome sequencing of 108 CRKP isolates from South China reveals ST11 dominance and emerging hvCRKP
Genomic analysis reveals resistance patterns in carbapenem-resistant Klebsiella pneumoniae from South China hospitals
This retrospective molecular epidemiology study characterized 108 carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates from multiple h…
Genomic analysis of South China hospitals found a new KPC-12 variant in carbapenem-resistant bacteria, alongside mutations that make these g…
Meta-analysis of antiretroviral therapy virologic suppression in HIV-positive pregnant and lactating women in Africa
New review shows HIV treatment success varies by age and adherence
This systematic review and meta-analysis evaluated virologic suppression among 304,883 HIV-positive pregnant and lactating women in Africa. …
In Africa, HIV treatment success for women varies by age and medicine adherence, with only 60.92% reaching the ideal undetectable viral load…
Pre-infection symptoms and functional status associated with long COVID risk in 65,464 U.S. adults
Did you know older age and female sex increase long COVID risk?
This retrospective cohort study of 65,464 U.S. adults with a history of COVID-19 enrolled in the All of Us Research Program examined the ris…
Older age, female sex, and lower mental health before infection raise long COVID risk, while having more pre-existing symptoms also increase…
Narrative review examines TCM herbal extracts and formulas regarding cholestatic liver injury
Your Gut Holds The Key To Liver Health
This narrative review synthesizes existing literature on the association between Traditional Chinese Medicine (TCM) herbal extracts and form…
Unbalanced gut bacteria disrupt bile flow and trigger liver inflammation, but Traditional Chinese Medicine strategies may restore balance an…
Narrative review discusses extracellular vesicles versus traditional nanocarriers for drug and vaccine delivery
Review compares extracellular vesicles to traditional nanocarriers for drug delivery
This narrative review examines the potential of extracellular vesicles (EVs) compared to traditional nanocarriers like lipid nanoparticles f…
Tiny natural particles called extracellular vesicles show promise as next-generation carriers for delivering medicines and vaccines into the…
HIV status and ART exposure associated with altered skin microbiome diversity and composition in Indonesia.
Does HIV change the bacteria living on your skin, and does treatment help?
This prospective observational study in Indonesia enrolled 244 participants, including people living with HIV, HIV-ART-naïve individuals, an…
HIV changes the bacteria living on your skin, and treatment helps bring those levels closer to normal.
Meta-analysis of 7,750 saliva samples validates non-invasive disease prediction models for nasopharyngeal carcinoma, colorectal cancer, and PLHIV.
Spit Test Could Predict Multiple Diseases
This meta-analysis reviewed public 16S saliva data from 22 cohorts involving 7,750 samples to assess multi-disease prediction models. The au…
A simple spit test might soon predict multiple diseases at once, offering a non-invasive way to check for serious health conditions without …