Alpha-glucosidase inhibitors like acarbose show anti-virulence activity against Candida albicans in vitro.
Could common diabetes drugs help stop fungal infections from building tough protective shields?
This systematic review evaluated alpha-glucosidase inhibitors, particularly acarbose, as selective antifungal inhibitors against Candida alb…
A common diabetes drug called acarbose may help break down the tough shields that hide dangerous fungal infections from treatment.
Systematic review examines pulmonary co-infection with M. septicum and M. nivoides
When One Lung Infection Is Really Two Sneaky Cousins
A systematic review of a pulmonary co-infection case and 19 additional M. septicum cases found both M. septicum and M. nivoides acted as cau…
Two nearly identical bacteria hiding in one lung infection may be evolving to become more aggressive while current lab tests miss them.
Systematic review of Mycobacterium riyadhense infection in 69 cases shows common presentations and drug susceptibility patterns.
A rare infection hits lungs and bones: what doctors need to know about treating Mycobacterium riyadhense.
A systematic review and meta-analysis of 69 immunocompetent and immunocompromised patients with Mycobacterium riyadhense infection found pne…
A rare lung and bone infection called Mycobacterium riyadhense often resists standard drugs, leaving doctors without agreed-upon treatment p…
Vaccines show protective effects against rotavirus and pneumococcal disease in sub-Saharan African children.
Vaccine Results Might Be Wrong Without These Factors
This systematic review and meta-analysis of 64 studies assessed vaccine effectiveness in children under five years in sub-Saharan Africa. Ro…
Vaccine studies in Africa often miss other health changes happening at the same time, which can make shots look more effective than they rea…
Relaxation of COVID-19 NPIs in Nanjing children showed high pathogen detection rates with preschoolers having the highest burden.
When COVID rules lifted, did kids get sicker or just catch more common bugs?
This retrospective cohort study examined 7,473 children (≤18 years) presenting with acute respiratory tract infections in a tertiary hospita…
After COVID rules lifted, common cold viruses and bacteria caused most children's breathing issues, with young kids facing the highest risk …
Streptococcus agalactiae is a predominant cause of prosthetic joint infections in adults with specific risk factors.
Hidden Bacteria: Why Your Diabetes Risks Bone Infections
This retrospective cohort study analyzed 1,454 adults in a West Region registry to identify risk factors for Streptococcus agalactiae bone a…
A hidden bacteria called S. agalactiae is the top cause of slow-healing bone infections in people with diabetes, obesity, or poor blood flow…
mNGS testing shows higher pathogen detection than culture in complex skin infections
A DNA-Reading Test Is Finding Infections That Standard Lab Cultures Miss
A retrospective cohort study of 69 patients with complex SSTIs found mNGS testing demonstrated significantly higher pathogen detection rates…
A new DNA test found infections in 83% of skin cases where standard lab cultures came back negative, helping doctors target the right bacter…
Peg-IFN-alpha treatment in HBeAg-negative chronic hepatitis B yields virological and serological responses.
New Blood Test Predicts Hep B Drug Success
This prospective cohort study evaluated HBeAg-negative chronic hepatitis B patients treated with pegylated interferon alpha over 48 weeks. V…
A new blood test checks specific genes to predict if hepatitis B patients will respond to treatment before wasting months on ineffective med…
One-stage revision shows comparable infection control to two-stage revision in chronic periprosthetic joint infection.
One Surgery Could Fix Your Joint Infection
This retrospective cohort study evaluated chronic periprosthetic joint infection (PJI) patients undergoing one-stage versus two-stage revisi…
One surgery for joint infections works as well as the standard two-stage process, letting patients recover faster without the long wait.
Pooled Xpert MTB/RIF Ultra testing shows high specificity but reduced sensitivity compared to individual testing in Vietnamese adults with presumptive tuberculosis.
Could testing TB samples in groups save money while still catching most cases?
This cross-sectional study evaluated pooled versus individual Xpert MTB/RIF Ultra testing among 2,396 adults with presumptive tuberculosis i…
Testing tuberculosis samples in groups saved over $14,000 and cut test kit use by nearly half while still catching most infections.
In Haiti, mosquito exposure linked to elevated IgG antibodies against specific salivary peptides in a low-transmission setting.
Mosquito Spit Is Becoming a Malaria Early Warning
This observational study enrolled 348 participants in Grand Anse, Haiti, to assess immune responses to Anopheles salivary peptides. Results …
A simple blood test now reveals how often people in Haiti have been bitten by malaria mosquitoes, helping health workers track invisible dis…
Antibiotic-resistant E. coli found on Welsh meat shows links to sheep but not human infections.
Your Dinner Meat May Carry Resistant Germs. Should You Worry?
This observational study assessed antibiotic-resistant Escherichia coli on beef and lamb steaks purchased from independent butchers in Wales…
A Welsh study found antibiotic-resistant germs on butcher meat, but the bugs rarely matched those causing human infections, suggesting limit…