Autoantibodies neutralizing type I interferons linked to severe COVID-19 pneumonia in myasthenia gravis patients
A Hidden Immune Flaw Makes COVID Far More Dangerous for Some Patients
An international cohort study of 85 unvaccinated, untreated SARS-CoV-2-infected MG patients found that those with autoantibodies neutralizin…
Doctors have discovered why some people with a common nerve disease face a terrifying risk from COVID-19, pointing to a simple way to keep t…
In Blantyre, Malawi, 17.4% of 2895 adolescents and adults aged 10-40 years had positive QuantiFERON-TB Gold Plus responses.
A Simple Blood Test Could Now Reveal Your Hidden Tuberculosis Risk
This community-based survey assessed quantitative interferon gamma release assay responses in 2895 adolescents and adults aged 10-40 years i…
Doctors may soon use a common test to pinpoint who is most likely to spread tuberculosis, allowing for smarter prevention.
Lake travel and occupational activities sustain Schistosoma mansoni infection risk in Ugandan villages near Lake Victoria.
Why a Deadly Parasite Won’t Let Go, Even When Villages Get Clean
This cross-sectional study assessed 585 individuals aged 1 to 91 years in five Ugandan villages near Lake Victoria. Routine travel to the la…
To finally stop a persistent parasitic disease, health programs may need to look beyond village borders and target the daily routines that k…
Cross-sectional analysis links SP resistance polymorphisms to gametocyte carriage in Mozambican malaria isolates.
Malaria Resistance in Mozambique Is Rising Fast
This cross-sectional molecular analysis examined 100 P. falciparum isolates from Mozambican pregnant women at delivery. Results indicate tha…
Malaria parasites in Mozambique are becoming resistant to the main pregnancy drug, increasing the risk of low birth weight and stillbirth fo…
Ultra-sensitive PCR on residual DBS shows 7.7% P. falciparum prevalence in Rwandan adults.
A Hidden Malaria Surge is Hiding in Plain Sight. Here’s the Truth.
This observational cross-sectional analysis examined residual dried blood spots from the 2019-20 Demographic and Health Surveys in Rwanda. A…
A new way of testing shows malaria is both more common and declining faster in Rwanda than we thought, offering a clearer map to finally bea…
Observational study finds 2024-2025 flu vaccine associated with reduced hospitalization and severe outcomes
The Flu Shot Didn't Stop Every Case — But It Halved the Worst Ones
An observational test-negative study in adults hospitalized with acute respiratory illness at 26 U.S. centers found the 2024-2025 seasonal i…
A large real-world study from 26 U.S. hospitals found that vaccinated adults were roughly half as likely to land in the ICU or die from flu …
HHBayes package enables simulation of household respiratory virus transmission and intervention effects
New Tool Makes Viral Spread in Homes Easier to Study
A software development study describes HHBayes, an open-source R package for simulating and analyzing household transmission data using Baye…
A new tool lets scientists simulate how viruses spread in homes, accounting for age differences and how vaccines change infection risks.
Willingness for new TB vaccine is 77% overall, higher in adolescents than adults in southern Mozambique.
A New TB Vaccine is Coming. Will People Actually Take It?
This mixed methods study surveyed 151 adults, adolescents, and caregivers in southern Mozambique regarding willingness to receive a new tube…
In places hit hardest by tuberculosis, most people are ready to say "yes" to a new vaccine that could save lives.
Interpretation of effective reproduction number R=1 as a stability threshold frequently fails and misclassifies complex dynamics.
Why R=1 is a Dangerous Lie
This study examines the interpretation of the effective reproduction number (R) as a stability threshold for infectious disease spread. Find…
A single average number hides dangerous virus signals, making outbreaks look stable when they are actually growing or shrinking.
Identical interventions yielded divergent epidemic suppression outcomes in computational models despite indistinguishable standard indicators.
Why High Infection Numbers Don't Always Mean You Need Stricter Rules
This computational modeling study compared pairs of epidemics with indistinguishable standard indicators against pairs with larger indicator…
Standard infection numbers can hide how well a specific plan will actually work, meaning two outbreaks looking identical might need very dif…
FDA Approves Cefepime for Injection and Dextrose Injection (cefepime) for Moderate to Severe Pneumonia and Other Infections
The FDA approved a new ready-to-use version of an antibiotic called cefepime for serious infections.
The FDA approved cefepime in a dextrose injection formulation for intravenous treatment of moderate to severe pneumonia, febrile neutropenia…
The FDA approved a ready-to-use antibiotic for serious infections like pneumonia and urinary tract infections in hospitalized patients.
Intravaginal vitamin C may increase short-term cure and prevent recurrence of bacterial vaginosis
Intravaginal Vitamin C May Help Treat Bacterial Vaginosis in Nonpregnant Patients
A meta-analysis of 1,107 nonpregnant patients found intravaginal vitamin C (250 mg daily for 6 days) was associated with higher short-term c…
Intravaginal vitamin C cured 66% of bacterial vaginosis patients in short-term trials, outperforming placebo and showing promise against sta…